AR032240A1 - Una composicion de vacuna profilactica y terapeutica que comprenden proteinas de envoltura purificadas de virus de hepatitis c - Google Patents
Una composicion de vacuna profilactica y terapeutica que comprenden proteinas de envoltura purificadas de virus de hepatitis cInfo
- Publication number
- AR032240A1 AR032240A1 ARP020100104A ARP020100104A AR032240A1 AR 032240 A1 AR032240 A1 AR 032240A1 AR P020100104 A ARP020100104 A AR P020100104A AR P020100104 A ARP020100104 A AR P020100104A AR 032240 A1 AR032240 A1 AR 032240A1
- Authority
- AR
- Argentina
- Prior art keywords
- protein
- proteins
- therapeutic vaccine
- compilition
- profilactic
- Prior art date
Links
- 102000004169 proteins and genes Human genes 0.000 title abstract 2
- 108090000623 proteins and genes Proteins 0.000 title abstract 2
- 229940021747 therapeutic vaccine Drugs 0.000 title abstract 2
- 241000711557 Hepacivirus Species 0.000 title 1
- 239000000203 mixture Substances 0.000 abstract 3
- 101710125507 Integrase/recombinase Proteins 0.000 abstract 2
- 101710185720 Putative ethidium bromide resistance protein Proteins 0.000 abstract 2
- 238000010494 dissociation reaction Methods 0.000 abstract 2
- 230000005593 dissociations Effects 0.000 abstract 2
- 101710091045 Envelope protein Proteins 0.000 abstract 1
- 101710188315 Protein X Proteins 0.000 abstract 1
- 102100021696 Syncytin-1 Human genes 0.000 abstract 1
- 239000002671 adjuvant Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 230000002934 lysing effect Effects 0.000 abstract 1
- 238000012544 monitoring process Methods 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 238000004393 prognosis Methods 0.000 abstract 1
- 230000000069 prophylactic effect Effects 0.000 abstract 1
- 229940021993 prophylactic vaccine Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/24011—Poxviridae
- C12N2710/24111—Orthopoxvirus, e.g. vaccinia virus, variola
- C12N2710/24141—Use of virus, viral particle or viral elements as a vector
- C12N2710/24143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
- C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Gastroenterology & Hepatology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Una composicion de vacuna profiláctica y terapéutica que comprende una cantidad efectiva de: al menos una proteína de envoltura purificada recombinante oligomérica específica o simple del HCV seleccionada de una proteína E1, una proteína E2 y partes de dichas proteínas E1 y E2; y de manera opcional un adyuvante farmacéuticamente aceptable. Dichas composiciones están caracterizadas en que al lisar las células huésped transformadas para aislar la proteína que se expresa de forma recombinante, se realiza una disociacion de enlace de bisulfuro o paso de reduccion con un agente de disociacion de enlace de bisulfuro. Además estas composiciones que comprenden dichos péptidos utiles para el pronostico y monitoreo de la efectividad clínica y/o resultado clínico del tratamiento del HCV
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US26066901P | 2001-01-11 | 2001-01-11 | |
| US31576801P | 2001-08-30 | 2001-08-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR032240A1 true AR032240A1 (es) | 2003-10-29 |
Family
ID=26948130
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP020100104A AR032240A1 (es) | 2001-01-11 | 2002-01-14 | Una composicion de vacuna profilactica y terapeutica que comprenden proteinas de envoltura purificadas de virus de hepatitis c |
Country Status (16)
| Country | Link |
|---|---|
| EP (1) | EP1463753A2 (es) |
| KR (1) | KR20020089371A (es) |
| CN (1) | CN1547588A (es) |
| AR (1) | AR032240A1 (es) |
| AU (1) | AU2002238502B2 (es) |
| BR (1) | BR0203518A (es) |
| CA (1) | CA2400643A1 (es) |
| CZ (1) | CZ20032164A3 (es) |
| HU (1) | HUP0302416A2 (es) |
| IL (1) | IL151033A0 (es) |
| MX (1) | MXPA02008886A (es) |
| NO (1) | NO20024325L (es) |
| PL (1) | PL363175A1 (es) |
| RU (1) | RU2313363C2 (es) |
| TR (1) | TR200202169T1 (es) |
| WO (1) | WO2002055548A2 (es) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4261195B2 (ja) | 2001-04-24 | 2009-04-30 | イノジェネティックス・ナムローゼ・フェンノートシャップ | 酵母のコア−グリコシル化されたｈｃｖエンベロープタンパク質の発現 |
| AU2003283365A1 (en) * | 2002-11-08 | 2004-06-07 | Innogenetics N.V. | HCV vaccine compositions comprising E1 and NS3 peptides |
| EP1561470A1 (en) * | 2003-06-20 | 2005-08-10 | Innogenetics N.V. | HCV vaccines comprising the envelope-1 (E1) protein or the corresponding DNA and at least one antiviral agent |
| KR20060087574A (ko) * | 2003-09-22 | 2006-08-02 | 가부시키가이샤 그린 펩티드 | Ｃ형 간염 바이러스 유래 펩티드 |
| CN100365124C (zh) * | 2005-10-27 | 2008-01-30 | 云南大学 | 一段丙型肝炎病毒特异性cDNA序列的应用 |
| CN115980352A (zh) * | 2022-12-30 | 2023-04-18 | 宁波博肽生物技术有限公司 | 一种hcv抗原包被预处理剂、抗原包被方法及检测试剂盒 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1996004385A2 (en) * | 1994-07-29 | 1996-02-15 | Innogenetics N.V. | Purified hepatitis c virus envelope proteins for diagnostic and therapeutic use |
-
2002
- 2002-01-11 PL PL02363175A patent/PL363175A1/xx unknown
- 2002-01-11 EP EP02704649A patent/EP1463753A2/en not_active Withdrawn
- 2002-01-11 TR TR2002/02169T patent/TR200202169T1/xx unknown
- 2002-01-11 IL IL15103302A patent/IL151033A0/xx unknown
- 2002-01-11 CZ CZ20032164A patent/CZ20032164A3/cs unknown
- 2002-01-11 RU RU2002121632/15A patent/RU2313363C2/ru not_active IP Right Cessation
- 2002-01-11 CN CNA028006097A patent/CN1547588A/zh active Pending
- 2002-01-11 BR BR0203518-9A patent/BR0203518A/pt not_active IP Right Cessation
- 2002-01-11 WO PCT/EP2002/000219 patent/WO2002055548A2/en not_active Ceased
- 2002-01-11 HU HU0302416A patent/HUP0302416A2/hu unknown
- 2002-01-11 AU AU2002238502A patent/AU2002238502B2/en not_active Ceased
- 2002-01-11 KR KR1020027011431A patent/KR20020089371A/ko not_active Abandoned
- 2002-01-11 CA CA002400643A patent/CA2400643A1/en not_active Abandoned
- 2002-01-11 MX MXPA02008886A patent/MXPA02008886A/es active IP Right Grant
- 2002-01-14 AR ARP020100104A patent/AR032240A1/es unknown
- 2002-09-10 NO NO20024325A patent/NO20024325L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| TR200202169T1 (tr) | 2004-06-21 |
| PL363175A1 (en) | 2004-11-15 |
| IL151033A0 (en) | 2003-04-10 |
| HUP0302416A2 (hu) | 2003-10-28 |
| WO2002055548A8 (en) | 2002-10-31 |
| AU2002238502B9 (en) | 2002-07-24 |
| BR0203518A (pt) | 2002-12-17 |
| WO2002055548A3 (en) | 2004-08-05 |
| RU2313363C2 (ru) | 2007-12-27 |
| MXPA02008886A (es) | 2003-04-25 |
| NO20024325L (no) | 2002-11-11 |
| WO2002055548A2 (en) | 2002-07-18 |
| AU2002238502B2 (en) | 2007-09-06 |
| AU2002238502A1 (en) | 2002-07-24 |
| RU2002121632A (ru) | 2004-03-20 |
| EP1463753A2 (en) | 2004-10-06 |
| KR20020089371A (ko) | 2002-11-29 |
| CZ20032164A3 (cs) | 2003-10-15 |
| CA2400643A1 (en) | 2002-07-18 |
| NO20024325D0 (no) | 2002-09-10 |
| CN1547588A (zh) | 2004-11-17 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Wiktor et al. | Antigenic properties of rabies virus components | |
| ES2174957T3 (es) | Proteinas purificadas de envoltura de virus de la hepatitis c para uso diagnostico y terapeutico. | |
| PT1090033E (pt) | Particulas de proteinas de envelope do hcv: utilizacao para vacinacao | |
| MXPA02011545A (es) | Virus del sindrome respiratorio y reproductor porcino (peesv), vacuna recombinante para el virus de la viruela. | |
| EA200300318A1 (ru) | Пептидомиметические ингибиторы протеазы | |
| BR0312474A (pt) | Partìcula viral adjuvante | |
| DE60039715D1 (de) | Hcv-impfstoff zusammensetzungen | |
| NO20044897L (no) | Hepatitt C virus inhibitorer | |
| JP2003528887A5 (es) | ||
| WO2002086100A3 (en) | Expression of core-glycosylated hcv envelope proteins in yeast | |
| CL2020000295A1 (es) | Métodos de terapia génica del factor viii (fviii) | |
| MXPA05005202A (es) | Vacuna. | |
| MXPA04005891A (es) | Proteinas envolventes del virus de hepatitis c purificadas para diagnostico y uso terapeutico. | |
| BR0206995A (pt) | Tratamento do vìrus da hepatite b | |
| SE9903031D0 (sv) | Peptide mixture and vaccine against a chronic viral infection | |
| LU et al. | Preparation and development of equine hyperimmune globulin F (ab′) 2 against severe acute respiratory syndrome coronavirus 1 | |
| EP1797112A4 (en) | INHIBITORS OF HEPATITIS C VIRUS | |
| WO2004041853A3 (en) | Hcv vaccine compositions comprising e1 and ns3 peptides | |
| TR200202169T1 (tr) | Tanı ve tedavide kullanım için pürifiye hepatit C virüsü zarf proteinleri. | |
| AR041515A1 (es) | Vacuna a dna contra el virus de papiloma humano | |
| ATE430167T1 (de) | Humaner rekombinanter antikörper gegen das hepatitis c (hcv) nichtstrukturelles ns3 protein, nukleinsäure und deren verwendungen | |
| RU2004104357A (ru) | Вакцинный состав, потенцированный комбинацией днк и антигена | |
| ECSP003414A (es) | Peptidos macrociclicos activos frente al virus de la hepatitis c | |
| JP2004525885A5 (es) |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |