AR032360A1 - Compuesto derivado de acido homoiminopiperidinil hexanoico, composicion farmaceutica que lo comprende y compuestos intermediarios que se usan en su preparacion - Google Patents

Compuesto derivado de acido homoiminopiperidinil hexanoico, composicion farmaceutica que lo comprende y compuestos intermediarios que se usan en su preparacion

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Publication number
AR032360A1
AR032360A1 ARP010103682A ARP010103682A AR032360A1 AR 032360 A1 AR032360 A1 AR 032360A1 AR P010103682 A ARP010103682 A AR P010103682A AR P010103682 A ARP010103682 A AR P010103682A AR 032360 A1 AR032360 A1 AR 032360A1
Authority
AR
Argentina
Prior art keywords
pharmaceutical composition
compounds used
preparation
compound derived
hexanoic
Prior art date
Application number
ARP010103682A
Other languages
English (en)
Inventor
Donald W Hansen Jr
Mahima Trivedi
Alok Awasthi
Thaddeus Franczyk
Jeffrey S Snyder
Alan E Moormann
Ronald Keith Webber
Original Assignee
Pharmacia Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Corp filed Critical Pharmacia Corp
Publication of AR032360A1 publication Critical patent/AR032360A1/es

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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D223/06—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D223/12—Nitrogen atoms not forming part of a nitro radical
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Abstract

Compuesto derivado del ácido homoiminopiperidinil hexanoico de formulas 1 a 3 y sales del mismo aceptable para el uso farmacéutico util en la inhibicion de la isoforma inducible de la oxido nítrico sintetasa. La composicion farmacéutica que lo comprende y los compuestos intermediarios utilizados en su preparacion seleccionados del grupo de formulas del 4 a 9.
ARP010103682A 2000-08-01 2001-08-01 Compuesto derivado de acido homoiminopiperidinil hexanoico, composicion farmaceutica que lo comprende y compuestos intermediarios que se usan en su preparacion AR032360A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US22217900P 2000-08-01 2000-08-01

Publications (1)

Publication Number Publication Date
AR032360A1 true AR032360A1 (es) 2003-11-05

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ARP010103682A AR032360A1 (es) 2000-08-01 2001-08-01 Compuesto derivado de acido homoiminopiperidinil hexanoico, composicion farmaceutica que lo comprende y compuestos intermediarios que se usan en su preparacion

Country Status (11)

Country Link
US (1) US6495544B2 (es)
EP (1) EP1305293A1 (es)
JP (1) JP2004512271A (es)
AR (1) AR032360A1 (es)
AU (1) AU2001281083A1 (es)
CA (1) CA2415851A1 (es)
EA (1) EA005817B1 (es)
MX (1) MXPA03000772A (es)
NZ (1) NZ523770A (es)
PE (1) PE20030413A1 (es)
WO (1) WO2002010139A1 (es)

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US7879840B2 (en) 2005-08-25 2011-02-01 The Trustees Of Columbia University In The City Of New York Agents for preventing and treating disorders involving modulation of the RyR receptors
US7718644B2 (en) 2004-01-22 2010-05-18 The Trustees Of Columbia University In The City Of New York Anti-arrhythmic and heart failure drugs that target the leak in the ryanodine receptor (RyR2) and uses thereof
US8022058B2 (en) 2000-05-10 2011-09-20 The Trustees Of Columbia University In The City Of New York Agents for preventing and treating disorders involving modulation of the RyR receptors
US7393652B2 (en) 2000-05-10 2008-07-01 The Trustees Of Columbia University In The City Of New York Methods for identifying a chemical compound that directly enhances binding of FKBP12.6 to PKA-phosphorylated type 2 ryanodine receptor (RyR2)
KR20050004155A (ko) * 2002-05-16 2005-01-12 파마시아 코포레이션 선택적 유도성 산화질소 신타아제 억제제를 이용한 호흡기질병 및 질환의 치료 방법
US7544678B2 (en) 2002-11-05 2009-06-09 The Trustees Of Columbia University In The City Of New York Anti-arrythmic and heart failure drugs that target the leak in the ryanodine receptor (RyR2)
US7125853B2 (en) * 2003-01-07 2006-10-24 Kemin Pharma B.V.B.A. Bicyclic carbohydrate compounds useful in the treatment of infections caused by Flaviviridae sp., such as hepatitis C and bovine viral diarrhea viruses
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EA200300030A1 (ru) 2003-08-28
CA2415851A1 (en) 2002-02-07
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US6495544B2 (en) 2002-12-17
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EA005817B1 (ru) 2005-06-30
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