AR036048A1 - Compuesto de piperazina; composiciones farmaceuticas formuladas con dicho compuesto y uso de las sales difumarato de dicho compuesto, en la preparacion de composiciones farmaceuticas para el tratamiento de trastornos tromboticos - Google Patents

Compuesto de piperazina; composiciones farmaceuticas formuladas con dicho compuesto y uso de las sales difumarato de dicho compuesto, en la preparacion de composiciones farmaceuticas para el tratamiento de trastornos tromboticos

Info

Publication number
AR036048A1
AR036048A1 ARP020102199A ARP020102199A AR036048A1 AR 036048 A1 AR036048 A1 AR 036048A1 AR P020102199 A ARP020102199 A AR P020102199A AR P020102199 A ARP020102199 A AR P020102199A AR 036048 A1 AR036048 A1 AR 036048A1
Authority
AR
Argentina
Prior art keywords
compound
pharmaceutical compositions
crystallization
treatment
difumarate
Prior art date
Application number
ARP020102199A
Other languages
English (en)
Spanish (es)
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/GB2001/002553 external-priority patent/WO2001096323A1/en
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of AR036048A1 publication Critical patent/AR036048A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ARP020102199A 2001-06-12 2002-06-11 Compuesto de piperazina; composiciones farmaceuticas formuladas con dicho compuesto y uso de las sales difumarato de dicho compuesto, en la preparacion de composiciones farmaceuticas para el tratamiento de trastornos tromboticos AR036048A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/GB2001/002553 WO2001096323A1 (en) 2000-06-13 2001-06-12 Serine protease inhibitors
US33929501P 2001-12-12 2001-12-12

Publications (1)

Publication Number Publication Date
AR036048A1 true AR036048A1 (es) 2004-08-04

Family

ID=41210812

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP020102199A AR036048A1 (es) 2001-06-12 2002-06-11 Compuesto de piperazina; composiciones farmaceuticas formuladas con dicho compuesto y uso de las sales difumarato de dicho compuesto, en la preparacion de composiciones farmaceuticas para el tratamiento de trastornos tromboticos

Country Status (13)

Country Link
US (1) US20040162295A1 (de)
EP (1) EP1397348B1 (de)
JP (1) JP2004534062A (de)
AR (1) AR036048A1 (de)
AT (1) ATE305452T1 (de)
AU (1) AU2002348501A1 (de)
DE (1) DE60206376T2 (de)
ES (1) ES2248618T3 (de)
MY (1) MY137876A (de)
PE (1) PE20030198A1 (de)
SV (1) SV2003001085A (de)
TW (1) TWI257389B (de)
WO (1) WO2002100847A2 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60224805T2 (de) 2001-07-26 2009-01-22 Eli Lilly And Co., Indianapolis 1-glycinyl-4-(1-methylpiperidin-4-yl)piperazine und -piperidine als faktor-xa-antagonisten
BR0308870A (pt) 2002-04-01 2005-01-04 Lilly Co Eli Composto, composição farmacêutica, processo para preparar um composto, uso de um composto, e método para tratar um distúrbio trombótico em um paciente
KR100849242B1 (ko) * 2004-06-30 2008-07-29 일라이 릴리 앤드 캄파니 1(인돌-6-카르보닐-ｄ-페닐글리시닐)-4-(1-메틸피페리딘-4-일) 피페라진 ｄ-타르트레이트
WO2006011955A1 (en) * 2004-06-30 2006-02-02 Eli Lilly And Company 1 (indole-6-carbonyl-d-phenylglycinyl) -4- (1-methylpiperidin-4-yl) piperazine d-tartrate
DE102007028407A1 (de) 2007-06-20 2008-12-24 Bayer Healthcare Ag Substituierte Oxazolidinone und ihre Verwendung
DE102007028319A1 (de) 2007-06-20 2008-12-24 Bayer Healthcare Ag Substituierte Oxazolidinone und ihre Verwendung
DE102007028406A1 (de) 2007-06-20 2008-12-24 Bayer Healthcare Ag Substituierte Oxazolidinone und ihre Verwendung
WO2014012859A1 (en) * 2012-07-19 2014-01-23 Boehringer Ingelheim International Gmbh Fumaric acid salt of 9-[4-(3-chloro-2-fluoro-phenylamino)-7-methoxy- chinazolin-6-yloxy]-1,4-diaza-spiro[5.5]undecan-5-one, its use as medicament and the preparation thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003502314A (ja) * 1999-06-14 2003-01-21 イーライ・リリー・アンド・カンパニー 化合物
GB0030304D0 (en) * 2000-12-13 2001-01-24 Lilly Co Eli Compounds

Also Published As

Publication number Publication date
MY137876A (en) 2009-03-31
US20040162295A1 (en) 2004-08-19
DE60206376D1 (de) 2006-02-09
PE20030198A1 (es) 2003-03-12
EP1397348B1 (de) 2005-09-28
DE60206376T2 (de) 2006-06-22
ES2248618T3 (es) 2006-03-16
WO2002100847A2 (en) 2002-12-19
AU2002348501A1 (en) 2002-12-23
JP2004534062A (ja) 2004-11-11
EP1397348A2 (de) 2004-03-17
WO2002100847A3 (en) 2003-08-21
SV2003001085A (es) 2003-03-18
ATE305452T1 (de) 2005-10-15
TWI257389B (en) 2006-07-01

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