NO20005497D0 - Heterocykliske derivater som inhiberer faktor Xa - Google Patents
Heterocykliske derivater som inhiberer faktor XaInfo
- Publication number
- NO20005497D0 NO20005497D0 NO20005497A NO20005497A NO20005497D0 NO 20005497 D0 NO20005497 D0 NO 20005497D0 NO 20005497 A NO20005497 A NO 20005497A NO 20005497 A NO20005497 A NO 20005497A NO 20005497 D0 NO20005497 D0 NO 20005497D0
- Authority
- NO
- Norway
- Prior art keywords
- heterocyclic derivatives
- inhibit factor
- relates
- antithrombotic
- anticoagulant
- Prior art date
Links
- 125000000623 heterocyclic group Chemical group 0.000 title abstract 3
- 108010074860 Factor Xa Proteins 0.000 title 1
- 230000002429 anti-coagulating effect Effects 0.000 abstract 2
- 230000002785 anti-thrombosis Effects 0.000 abstract 2
- 239000003146 anticoagulant agent Substances 0.000 abstract 2
- 238000004519 manufacturing process Methods 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 241001465754 Metazoa Species 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9809351.1A GB9809351D0 (en) | 1998-05-02 | 1998-05-02 | Heterocyclic derivatives |
| GBGB9903337.5A GB9903337D0 (en) | 1999-02-16 | 1999-02-16 | Heterocyclic derivatives |
| PCT/GB1999/001308 WO1999057113A1 (en) | 1998-05-02 | 1999-04-27 | Heterocyclic derivatives which inhibit factor xa |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO20005497D0 true NO20005497D0 (no) | 2000-11-01 |
| NO20005497L NO20005497L (no) | 2000-12-21 |
| NO320893B1 NO320893B1 (no) | 2006-02-06 |
Family
ID=26313572
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20005497A NO320893B1 (no) | 1998-05-02 | 2000-11-01 | Heterocykliske derivater som inhiberer faktor Xa og anvendelse derav, samt farmasoytisk sammensetning. |
Country Status (22)
| Country | Link |
|---|---|
| US (2) | US6753331B1 (no) |
| EP (2) | EP1528061A1 (no) |
| JP (1) | JP2002513790A (no) |
| KR (1) | KR20010043246A (no) |
| CN (1) | CN1133634C (no) |
| AT (1) | ATE282610T1 (no) |
| AU (1) | AU754453B2 (no) |
| BR (1) | BR9910179A (no) |
| CA (1) | CA2331042A1 (no) |
| DE (1) | DE69921994T2 (no) |
| EE (1) | EE200000527A (no) |
| ES (1) | ES2232131T3 (no) |
| HU (1) | HUP0101712A3 (no) |
| IL (1) | IL139406A (no) |
| NO (1) | NO320893B1 (no) |
| NZ (1) | NZ507835A (no) |
| PL (1) | PL343706A1 (no) |
| PT (1) | PT1082321E (no) |
| SI (1) | SI1082321T1 (no) |
| SK (1) | SK16512000A3 (no) |
| TR (1) | TR200003200T2 (no) |
| WO (1) | WO1999057113A1 (no) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL115420A0 (en) | 1994-09-26 | 1995-12-31 | Zeneca Ltd | Aminoheterocyclic derivatives |
| GB9902989D0 (en) * | 1999-02-11 | 1999-03-31 | Zeneca Ltd | Heterocyclic derivatives |
| GB9914342D0 (en) * | 1999-06-19 | 1999-08-18 | Zeneca Ltd | Compound |
| GB9917344D0 (en) * | 1999-07-24 | 1999-09-22 | Zeneca Ltd | Novel salt |
| TWI290136B (en) | 2000-04-05 | 2007-11-21 | Daiichi Seiyaku Co | Ethylenediamine derivatives |
| GB0012448D0 (en) | 2000-05-24 | 2000-07-12 | Astrazeneca Ab | New process |
| CN100408099C (zh) * | 2000-11-09 | 2008-08-06 | 阿斯特拉曾尼卡有限公司 | 含有嵌段共聚物的口服药物组合物 |
| GB0104752D0 (en) * | 2001-02-27 | 2001-04-18 | Astrazeneca Ab | Pharmaceutical compositions |
| WO2003000657A1 (en) | 2001-06-20 | 2003-01-03 | Daiichi Pharmaceutical Co., Ltd. | Diamine derivatives |
| EP1569912B1 (en) | 2002-12-03 | 2015-04-29 | Pharmacyclics, Inc. | 2-(2-hydroxybiphenyl-3-yl)-1h-benzoimidazole-5-carboxamidine derivatives as factor viia inhibitors |
| WO2004108671A1 (en) * | 2003-06-06 | 2004-12-16 | Suven Life Sciences Limited | Substituted indoles with serotonin receptor affinity, process for their preparation and pharmaceutical compositions containing them |
| WO2005012293A1 (ja) * | 2003-08-01 | 2005-02-10 | Nippon Soda Co., Ltd. | フェニルアゾール化合物、製造法および抗酸化薬 |
| SE0400014D0 (sv) * | 2004-01-08 | 2004-01-08 | Astrazeneca Ab | Heterocyclic derivatives |
| WO2007008145A1 (en) * | 2005-07-08 | 2007-01-18 | Astrazeneca Ab | Heterocyclic sulfonamide derivatives as inhibitors of factor xa |
| WO2007008144A1 (en) * | 2005-07-08 | 2007-01-18 | Astrazeneca Ab | Heterocyclic sulfonamide derivatives as inhibitors of factor xa |
| US20080214495A1 (en) * | 2005-07-08 | 2008-09-04 | Astrazeneca Ab | Heterocyclic Sulfonamide Derivatives as Inhibitors of Factor Xa |
| US20080221063A1 (en) * | 2005-07-08 | 2008-09-11 | Astrazeneca Ab | Heterocyclic Sulfonamide Derivatives As Inhibitors Of Factor Xa |
| MD3762368T2 (ro) | 2018-03-08 | 2022-07-31 | Incyte Corp | Compuși diol aminopirazină ca inhibitori ai PI3K-Y |
| US11046658B2 (en) | 2018-07-02 | 2021-06-29 | Incyte Corporation | Aminopyrazine derivatives as PI3K-γ inhibitors |
| BR112021026410A2 (pt) | 2019-07-01 | 2022-02-08 | Tonix Pharma Ltd | Anticorpos anti-cd154 e usos dos mesmos |
| JP2024503625A (ja) | 2021-01-06 | 2024-01-26 | トニックス ファーマ リミテッド | 改変された抗ｃｄ１５４抗体により免疫寛容を誘導する方法 |
| WO2025248134A1 (en) | 2024-05-31 | 2025-12-04 | Tonix Pharma Limited | Treatment methods comprising administration of modified cd154 antibodies |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL115420A0 (en) * | 1994-09-26 | 1995-12-31 | Zeneca Ltd | Aminoheterocyclic derivatives |
| AU1335897A (en) * | 1995-12-21 | 1997-07-17 | Du Pont Merck Pharmaceutical Company, The | Isoxazoline, isothiazoline and pyrazoline factor xa inhibitors |
| GB9602166D0 (en) * | 1996-02-02 | 1996-04-03 | Zeneca Ltd | Aminoheterocyclic derivatives |
| GB9602294D0 (en) | 1996-02-05 | 1996-04-03 | Zeneca Ltd | Heterocyclic compounds |
| UA56197C2 (uk) * | 1996-11-08 | 2003-05-15 | Зенека Лімітед | Гетероциклічні похідні |
| WO1998054164A1 (en) * | 1997-05-30 | 1998-12-03 | Takeda Chemical Industries, Ltd. | Sulfonamide derivatives, their production and use |
| GB9715894D0 (en) * | 1997-07-29 | 1997-10-01 | Zeneca Ltd | Heterocyclic derivatives |
| DE19743435A1 (de) * | 1997-10-01 | 1999-04-08 | Merck Patent Gmbh | Benzamidinderivate |
-
1999
- 1999-04-27 AU AU36206/99A patent/AU754453B2/en not_active Ceased
- 1999-04-27 DE DE69921994T patent/DE69921994T2/de not_active Expired - Lifetime
- 1999-04-27 CN CNB99808218XA patent/CN1133634C/zh not_active Expired - Fee Related
- 1999-04-27 HU HU0101712A patent/HUP0101712A3/hu unknown
- 1999-04-27 CA CA002331042A patent/CA2331042A1/en not_active Abandoned
- 1999-04-27 PT PT99918178T patent/PT1082321E/pt unknown
- 1999-04-27 TR TR2000/03200T patent/TR200003200T2/xx unknown
- 1999-04-27 EP EP04022155A patent/EP1528061A1/en not_active Withdrawn
- 1999-04-27 WO PCT/GB1999/001308 patent/WO1999057113A1/en not_active Ceased
- 1999-04-27 PL PL99343706A patent/PL343706A1/xx not_active Application Discontinuation
- 1999-04-27 IL IL13940699A patent/IL139406A/en not_active IP Right Cessation
- 1999-04-27 AT AT99918178T patent/ATE282610T1/de not_active IP Right Cessation
- 1999-04-27 US US09/674,559 patent/US6753331B1/en not_active Expired - Fee Related
- 1999-04-27 NZ NZ507835A patent/NZ507835A/xx unknown
- 1999-04-27 SI SI9930725T patent/SI1082321T1/xx unknown
- 1999-04-27 SK SK1651-2000A patent/SK16512000A3/sk unknown
- 1999-04-27 BR BR9910179-3A patent/BR9910179A/pt not_active Application Discontinuation
- 1999-04-27 JP JP2000547083A patent/JP2002513790A/ja active Pending
- 1999-04-27 EP EP99918178A patent/EP1082321B1/en not_active Expired - Lifetime
- 1999-04-27 KR KR1020007012193A patent/KR20010043246A/ko not_active Ceased
- 1999-04-27 ES ES99918178T patent/ES2232131T3/es not_active Expired - Lifetime
- 1999-04-27 EE EEP200000527A patent/EE200000527A/xx unknown
-
2000
- 2000-11-01 NO NO20005497A patent/NO320893B1/no unknown
-
2004
- 2004-04-06 US US10/817,960 patent/US20040266759A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| ATE282610T1 (de) | 2004-12-15 |
| JP2002513790A (ja) | 2002-05-14 |
| IL139406A0 (en) | 2001-11-25 |
| ES2232131T3 (es) | 2005-05-16 |
| CN1308631A (zh) | 2001-08-15 |
| HUP0101712A3 (en) | 2003-01-28 |
| CN1133634C (zh) | 2004-01-07 |
| SK16512000A3 (sk) | 2001-05-10 |
| IL139406A (en) | 2004-07-25 |
| US6753331B1 (en) | 2004-06-22 |
| CA2331042A1 (en) | 1999-11-11 |
| DE69921994D1 (de) | 2004-12-23 |
| HK1034711A1 (en) | 2001-11-02 |
| NZ507835A (en) | 2003-01-31 |
| SI1082321T1 (en) | 2005-06-30 |
| BR9910179A (pt) | 2001-01-09 |
| TR200003200T2 (tr) | 2001-02-21 |
| AU754453B2 (en) | 2002-11-14 |
| NO20005497L (no) | 2000-12-21 |
| EP1082321A1 (en) | 2001-03-14 |
| AU3620699A (en) | 1999-11-23 |
| EE200000527A (et) | 2002-02-15 |
| EP1082321B1 (en) | 2004-11-17 |
| US20040266759A1 (en) | 2004-12-30 |
| PL343706A1 (en) | 2001-08-27 |
| PT1082321E (pt) | 2005-03-31 |
| NO320893B1 (no) | 2006-02-06 |
| HUP0101712A2 (hu) | 2001-11-28 |
| DE69921994T2 (de) | 2005-12-01 |
| WO1999057113A1 (en) | 1999-11-11 |
| EP1528061A1 (en) | 2005-05-04 |
| KR20010043246A (ko) | 2001-05-25 |
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