AR036066A2 - Metodo para suministrar una droga a un ojo humano - Google Patents

Metodo para suministrar una droga a un ojo humano

Info

Publication number
AR036066A2
AR036066A2 ARP030101032A ARP030101032A AR036066A2 AR 036066 A2 AR036066 A2 AR 036066A2 AR P030101032 A ARP030101032 A AR P030101032A AR P030101032 A ARP030101032 A AR P030101032A AR 036066 A2 AR036066 A2 AR 036066A2
Authority
AR
Argentina
Prior art keywords
drug
human eye
sclera
eye
cannula
Prior art date
Application number
ARP030101032A
Other languages
English (en)
Original Assignee
Alcon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Inc filed Critical Alcon Inc
Publication of AR036066A2 publication Critical patent/AR036066A2/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A61F9/0017Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0058Additional features; Implant or prostheses properties not otherwise provided for
    • A61F2250/0067Means for introducing or releasing pharmaceutical products into the body

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Prostheses (AREA)

Abstract

Un método para suministrar una droga a un ojo humano que comprende: insertar la cánula por debajo de la cápsula de Tenon y por encima de la esclera del ojo humano en un punto posterior al limbo del ojo, dicha cánula comprende una porción distal que tiene un radio de curvatura sustancialmente igual al radio de curvatura de la esclera de dicho ojo; e inyectar una droga a través de dicha cánula para formar un depot de droga sobre la superficie externa de dicha esclera, comprendiendo dicha droga un agente farmacéuticamente activo seleccionado del grupo formado por 4,9(11)-pregnadien-17alfa,21-diol-3,20-diona-21-acetato.
ARP030101032A 1999-10-21 2003-03-25 Metodo para suministrar una droga a un ojo humano AR036066A2 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US16166099P 1999-10-21 1999-10-21

Publications (1)

Publication Number Publication Date
AR036066A2 true AR036066A2 (es) 2004-08-11

Family

ID=22582174

Family Applications (4)

Application Number Title Priority Date Filing Date
ARP000105478A AR026075A1 (es) 1999-10-21 2000-10-18 Una canula para distribucion sub-tenon de una droga
ARP030101032A AR036066A2 (es) 1999-10-21 2003-03-25 Metodo para suministrar una droga a un ojo humano
ARP030101036A AR039133A2 (es) 1999-10-21 2003-03-25 Canula
ARP030101031A AR036065A2 (es) 1999-10-21 2003-03-25 Un metodo para suministrar una droga en el ojo humano

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ARP000105478A AR026075A1 (es) 1999-10-21 2000-10-18 Una canula para distribucion sub-tenon de una droga

Family Applications After (2)

Application Number Title Priority Date Filing Date
ARP030101036A AR039133A2 (es) 1999-10-21 2003-03-25 Canula
ARP030101031A AR036065A2 (es) 1999-10-21 2003-03-25 Un metodo para suministrar una droga en el ojo humano

Country Status (15)

Country Link
US (1) US6413245B1 (es)
EP (2) EP1221918B1 (es)
JP (1) JP2003511204A (es)
AR (4) AR026075A1 (es)
AT (1) ATE290837T1 (es)
AU (1) AU775149B2 (es)
BR (1) BR0014930B1 (es)
CA (1) CA2383572C (es)
DE (1) DE60018777T2 (es)
ES (1) ES2240180T3 (es)
HK (1) HK1049438B (es)
MX (1) MXPA02002376A (es)
PT (1) PT1221918E (es)
TW (1) TW467740B (es)
WO (1) WO2001028473A1 (es)

Families Citing this family (188)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6936053B1 (en) * 1998-07-02 2005-08-30 Jeffrey N. Weiss Ocular implant needle
KR20020035476A (ko) * 1999-04-26 2002-05-11 지엠피 비젼 솔루션즈 인코포레이티드 측로 장치 및 녹내장 치료 방법
US7943162B2 (en) * 1999-10-21 2011-05-17 Alcon, Inc. Drug delivery device
CA2369149A1 (en) * 2000-02-02 2001-08-09 Meditsinsky Nauchno-Issledovatelsky Oftalmologichesky Tsentr "Novy Vzgjyad" Kourenkov's cannula used for a method for an operation of refractory-correlating eximer-laser intrastromal keratectomy (reik)
US7431710B2 (en) 2002-04-08 2008-10-07 Glaukos Corporation Ocular implants with anchors and methods thereof
DE60217679T2 (de) 2001-07-23 2007-10-25 Alcon Inc. Vorrichtung zur freisetzung eines ophthalmischen arzneimittels
EP1385452B1 (en) * 2001-07-23 2006-09-13 Alcon, Inc. Ophthalmic drug delivery device
JP4892800B2 (ja) * 2001-08-24 2012-03-07 株式会社ジェイ・エム・エス 薬液注入用針管、および該薬液注入用針管を装着した注射器
US7153316B1 (en) 2001-11-09 2006-12-26 Mcdonald Marguerite B Surgical instruments and method for corneal reformation
US6802829B2 (en) * 2001-11-16 2004-10-12 Infinite Vision, Llc Spray device
WO2003068253A1 (en) * 2002-02-14 2003-08-21 Merck Patent Gmbh Methods and compositions for the treatment of eye diseases
JP2004041492A (ja) * 2002-07-12 2004-02-12 Scitec Kk 医療用針
DE10238310A1 (de) * 2002-08-21 2004-03-04 Erich Jaeger Gmbh Elektrodenanordnung
EP1539066B1 (en) * 2002-09-17 2012-11-07 Iscience Surgical Corporation Apparatus surgical bypass of aqueous humor
CA2689424A1 (en) * 2002-09-29 2004-04-08 Surmodics, Inc. Methods for treatment and/or prevention of retinal disease
US7141048B1 (en) * 2002-10-17 2006-11-28 Alcon, Inc. Vitreoretinal instrument
US7285107B1 (en) 2002-10-17 2007-10-23 Alcon, Inc. Vitreoretinal instrument
ZA200505990B (en) * 2003-02-20 2006-12-27 Alcon Inc Formulations of glucocorticoids to treat pathologic ocular angiogenesis
MXPA05008561A (es) * 2003-02-20 2005-11-04 Alcon Inc Uso de esteroides para tratar personas que sufren de trastornos oculares.
US20040199130A1 (en) * 2003-04-03 2004-10-07 Chornenky Victor I. Apparatus and method for treatment of macular degeneration
WO2004112772A1 (en) * 2003-06-13 2004-12-29 Alcon, Inc. Formulations of non-steroidal anti-inflammatory agents to treat pathologic ocular angiogenesis
JP2007521274A (ja) * 2003-06-20 2007-08-02 アルコン,インコーポレイテッド 複数成分の組み合わせを用いる加齢性黄斑変性の処置
KR20060082792A (ko) * 2003-07-10 2006-07-19 알콘, 인코퍼레이티드 안과용 약물 전달 장치
DE10337863A1 (de) 2003-08-18 2005-03-17 Merck Patent Gmbh Verwendung von Chromen-4-on-Derivaten
CA2536185C (en) * 2003-08-20 2012-06-26 Santen Pharmaceutical Co., Ltd. Drug delivery system by administrating fine particles to sub-tenon
JP4869930B2 (ja) * 2003-08-26 2012-02-08 ヴィスタ サイエンティフィック エルエルシー 眼科薬物供給装置
JP2007505932A (ja) 2003-09-18 2007-03-15 マクサイト, インコーポレイテッド 経強膜送達
US20050098470A1 (en) * 2003-11-12 2005-05-12 Davis Michael J. Kit for administration of a drug
US20090148527A1 (en) * 2007-12-07 2009-06-11 Robinson Michael R Intraocular formulation
WO2005107664A2 (en) * 2004-04-29 2005-11-17 Iscience Interventional Corporation Apparatus and method for surgical enhancement of aqueous humor drainage
US20080058704A1 (en) * 2004-04-29 2008-03-06 Michael Hee Apparatus and Method for Ocular Treatment
WO2006002366A2 (en) * 2004-06-24 2006-01-05 Surmodics, Inc. Biodegradable ocular devices, methods and systems
US20060110428A1 (en) 2004-07-02 2006-05-25 Eugene Dejuan Methods and devices for the treatment of ocular conditions
US20060047250A1 (en) * 2004-08-30 2006-03-02 Hickingbotham Dyson W Fluid delivery device
US7402156B2 (en) 2004-09-01 2008-07-22 Alcon, Inc. Counter pressure device for ophthalmic drug delivery
US7226435B2 (en) * 2004-10-14 2007-06-05 Alcon, Inc. Drug delivery device
EP1819325A2 (en) * 2004-12-22 2007-08-22 Alcon, Inc. Device for ophthalmic drug delivery
US8663639B2 (en) 2005-02-09 2014-03-04 Santen Pharmaceutical Co., Ltd. Formulations for treating ocular diseases and conditions
WO2006086750A1 (en) 2005-02-09 2006-08-17 Macusight, Inc. Liquid formulations for treatment of diseases or conditions
WO2006088134A1 (ja) * 2005-02-18 2006-08-24 Santen Pharmaceutical Co., Ltd. ステロイド化合物の副作用軽減または回避方法
JP2006257080A (ja) * 2005-02-18 2006-09-28 Santen Pharmaceut Co Ltd ステロイド化合物の副作用軽減または回避方法
US20100196509A1 (en) 2005-02-28 2010-08-05 Jonathan Braun Methods for Diagnosis and Treatment of Endometrial Cancer
CN101180086A (zh) * 2005-04-08 2008-05-14 苏尔莫迪克斯公司 用于经视网膜下递送的持续释放植入物
US8318906B2 (en) 2005-04-15 2012-11-27 The Regents Of The University Of California EMP2 antibodies and their therapeutic uses
US20070038174A1 (en) * 2005-08-09 2007-02-15 Hopkins Mark A Ophthalmic injector system
US20070060887A1 (en) * 2005-08-22 2007-03-15 Marsh David A Ophthalmic injector
US20070134244A1 (en) * 2005-10-14 2007-06-14 Alcon, Inc. Combination treatment for pathologic ocular angiogenesis
WO2007052662A1 (ja) * 2005-10-31 2007-05-10 Terumo Kabushiki Kaisha 穿刺器具、投与器具及び穿刺方法
US7611492B2 (en) * 2005-11-10 2009-11-03 Terumo Kabushiki Kaisha Puncture device
US20070156096A1 (en) * 2005-11-10 2007-07-05 Terumo Kabushiki Kaisha Puncture device
KR20080087814A (ko) * 2005-12-22 2008-10-01 알콘 리서치, 리미티드 보체 인자 h의 위험 변이체가 있는 환자에서 연령 관련황반변성의 예방 및 치료를 위한 c3-전환효소 저해제
US8492400B2 (en) 2006-02-09 2013-07-23 Santen Pharmaceutical Co., Ltd. Stable formulations, and methods of their preparation and use
US20070202186A1 (en) 2006-02-22 2007-08-30 Iscience Interventional Corporation Apparatus and formulations for suprachoroidal drug delivery
CN101443004B (zh) 2006-03-23 2013-03-06 参天制药株式会社 用于与血管通透性有关的疾病或病症的制剂
US8197435B2 (en) * 2006-05-02 2012-06-12 Emory University Methods and devices for drug delivery to ocular tissue using microneedle
US20210393436A1 (en) * 2006-05-02 2021-12-23 Emory University Methods and devices for drug delivery to ocular tissue using microneedle
US20070270750A1 (en) * 2006-05-17 2007-11-22 Alcon, Inc. Drug delivery device
US7871399B2 (en) * 2006-05-17 2011-01-18 Alcon Research, Ltd. Disposable ophthalmic injection device
US7862540B2 (en) * 2006-05-17 2011-01-04 Alcon Research, Ltd. Ophthalmic injection device using shape memory alloy
US7811252B2 (en) * 2006-05-17 2010-10-12 Alcon Research, Ltd. Dosage control device
US7887521B2 (en) * 2006-05-17 2011-02-15 Alcon Research, Ltd. Ophthalmic injection system
US20070270768A1 (en) * 2006-05-17 2007-11-22 Bruno Dacquay Mechanical Linkage Mechanism For Ophthalmic Injection Device
US7674243B2 (en) * 2006-05-17 2010-03-09 Alcon Inc. Ophthalmic injection device using piezoelectric array
US20070268340A1 (en) * 2006-05-17 2007-11-22 Bruno Dacquay Ophthalmic Injection System and Method Using Piezoelectric Array
US20080097379A1 (en) * 2006-09-26 2008-04-24 Alcon Manufacturing, Ltd. Ophthalmic injection method
US20080125712A1 (en) * 2006-09-26 2008-05-29 Alcon Manufacturing, Ltd. Ophthalmic injection system
US20080097390A1 (en) * 2006-09-27 2008-04-24 Alcon Manufacturing, Ltd. Spring actuated delivery system
BRMU8602090Y8 (pt) * 2006-10-05 2021-06-22 Hexsel Doris disposição aplicada a cânula para preenchimentos cutâneos
US9022970B2 (en) 2006-10-16 2015-05-05 Alcon Research, Ltd. Ophthalmic injection device including dosage control device
ATE490752T1 (de) * 2006-10-16 2010-12-15 Alcon Res Ltd Universelle aufladbare baugruppe mit eingeschränkter wiederverwendbarkeit für ein ophthalmisches handstück
BRPI0717644A2 (pt) * 2006-10-16 2013-11-12 Alcon Res Ltd Método de operação de peça manual oftálmica com extremidade descartável.
US20080281292A1 (en) * 2006-10-16 2008-11-13 Hickingbotham Dyson W Retractable Injection Port
US8969415B2 (en) * 2006-12-01 2015-03-03 Allergan, Inc. Intraocular drug delivery systems
US20080265343A1 (en) * 2007-04-26 2008-10-30 International Business Machines Corporation Field effect transistor with inverted t shaped gate electrode and methods for fabrication thereof
RU2009144142A (ru) * 2007-04-30 2011-06-10 Алькон Рисерч, Лтд. (Us) Лечение возрастной дегенерации желтого пятна с применением ингибиторов фактора d комплемента
US20090018512A1 (en) * 2007-07-13 2009-01-15 Charles Steven T Pneumatically-Powered Ophthalmic Injector
US20090018548A1 (en) * 2007-07-13 2009-01-15 Charles Steven T Pneumatically-Powered Intraocular Lens Injection Device with Removable Cartridge
US7740619B2 (en) * 2007-08-01 2010-06-22 Alcon Research, Ltd. Spring driven ophthalmic injection device with safety actuator lockout feature
US7629768B2 (en) * 2007-08-03 2009-12-08 Alcon Research, Ltd. Easy cleaning C-shaped charging base
US20090036842A1 (en) * 2007-08-03 2009-02-05 Raffi Pinedjian Consumable Activation Lever For Injection Device
USD592746S1 (en) 2007-11-08 2009-05-19 Alimera Sciences Ocular implantation device
US9849027B2 (en) 2007-11-08 2017-12-26 Alimera Sciences, Inc. Ocular implantation device
US8790366B2 (en) * 2007-11-13 2014-07-29 Alcon Research, Ltd. Fan-shaped cannula for sealing ophthalmic incisions
US8608632B1 (en) * 2009-07-03 2013-12-17 Salutaris Medical Devices, Inc. Methods and devices for minimally-invasive extraocular delivery of radiation and/or pharmaceutics to the posterior portion of the eye
US9056201B1 (en) * 2008-01-07 2015-06-16 Salutaris Medical Devices, Inc. Methods and devices for minimally-invasive delivery of radiation to the eye
KR101634983B1 (ko) * 2008-01-07 2016-07-01 살루타리스 메디컬 디바이스즈, 인코퍼레이티드 눈의 후부에 대한 방사선의 전달을 위한 외안의 최소한의 수술 방법 및 장치
US10022558B1 (en) * 2008-01-07 2018-07-17 Salutaris Medical Devices, Inc. Methods and devices for minimally-invasive delivery of radiation to the eye
US8602959B1 (en) 2010-05-21 2013-12-10 Robert Park Methods and devices for delivery of radiation to the posterior portion of the eye
AU2015204094B2 (en) * 2008-01-07 2017-02-23 Salutaris Medical Devices, Inc Methods and devices for minimally-invasive extraocular delivery of radiation to the posterior portion of the eye
US9873001B2 (en) * 2008-01-07 2018-01-23 Salutaris Medical Devices, Inc. Methods and devices for minimally-invasive delivery of radiation to the eye
GB0802044D0 (en) * 2008-02-05 2008-03-12 Helica Instr Ltd Needle for opthalmic procedures
TWI607748B (zh) * 2008-04-24 2017-12-11 莎魯塔理斯醫療設備股份有限公司 用於最小侵入性眼外遞送輻射至眼睛後部之方法及裝置
US8945086B2 (en) * 2008-07-01 2015-02-03 Bruce Becker Retrobulbar needle and methods of use
US8821870B2 (en) 2008-07-18 2014-09-02 Allergan, Inc. Method for treating atrophic age related macular degeneration
WO2010019839A1 (en) 2008-08-15 2010-02-18 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Methods for using interferon gamma to absorb fluid from the subretinal space
US20100098772A1 (en) * 2008-10-21 2010-04-22 Allergan, Inc. Drug delivery systems and methods for treating neovascularization
US8702677B2 (en) * 2008-10-31 2014-04-22 Warsaw Orthopedic, Inc. Device and method for directional delivery of a drug depot
US9095506B2 (en) 2008-11-17 2015-08-04 Allergan, Inc. Biodegradable alpha-2 agonist polymeric implants and therapeutic uses thereof
AU2009322409A1 (en) 2008-12-04 2011-06-23 Sanofi Crystalline forms
AR074776A1 (es) 2008-12-18 2011-02-09 Sanofi Aventis Metodo para tratar la degeneracion macular; modulando el sistema inmunitario del paciente
USD691269S1 (en) 2009-01-07 2013-10-08 Salutaris Medical Devices, Inc. Fixed-shape cannula for posterior delivery of radiation to an eye
USD691268S1 (en) 2009-01-07 2013-10-08 Salutaris Medical Devices, Inc. Fixed-shape cannula for posterior delivery of radiation to eye
USD691270S1 (en) 2009-01-07 2013-10-08 Salutaris Medical Devices, Inc. Fixed-shape cannula for posterior delivery of radiation to an eye
USD691267S1 (en) 2009-01-07 2013-10-08 Salutaris Medical Devices, Inc. Fixed-shape cannula for posterior delivery of radiation to eye
USD642266S1 (en) 2010-08-24 2011-07-26 Marsteller Laurence J Brachytherapy device
US8425473B2 (en) 2009-01-23 2013-04-23 Iscience Interventional Corporation Subretinal access device
US20100191177A1 (en) * 2009-01-23 2010-07-29 Iscience Interventional Corporation Device for aspirating fluids
USD616088S1 (en) 2009-02-06 2010-05-18 Luca Brigatti Fixed-shaped cannula for posterior delivery of radiation to eye
USD615645S1 (en) 2009-02-06 2010-05-11 Luca Brigatti Fixed-shape cannula for posterior delivery of radiation to eye
USD616540S1 (en) 2009-02-06 2010-05-25 Luca Brigatti Fixed-shape cannula for posterior delivery of radiation to eye
USD616087S1 (en) 2009-02-06 2010-05-18 Luca Brigatti Fixed-shape cannula for posterior delivery of radiation to eye
US8372036B2 (en) 2009-05-06 2013-02-12 Alcon Research, Ltd. Multi-layer heat assembly for a drug delivery device
US10206813B2 (en) 2009-05-18 2019-02-19 Dose Medical Corporation Implants with controlled drug delivery features and methods of using same
US12478503B2 (en) 2009-05-18 2025-11-25 Glaukos Corporation Implants with controlled drug delivery features and methods of using same
JP5937004B2 (ja) 2009-05-18 2016-06-22 ドーズ メディカル コーポレーションDose Medical Corporation 薬剤溶出眼内インプラント
WO2011011753A1 (en) 2009-07-23 2011-01-27 Baxter International Inc. Manufacture of factor h (fh) and fh-derivatives from plasma
RU2405575C1 (ru) * 2009-08-17 2010-12-10 Владимир Константинович Гаврилов Медицинская игла
CA2781290A1 (en) 2009-11-20 2011-05-26 Lynn K. Gordon Epithelial membrane protein-2 (emp2) and proliferative vitreoretinopathy (pvr)
US8177747B2 (en) 2009-12-22 2012-05-15 Alcon Research, Ltd. Method and apparatus for drug delivery
SI2515774T1 (sl) 2009-12-23 2014-06-30 Alcon Research, Ltd. Oftalmološka kanila troakarja z ventilom
US8529492B2 (en) 2009-12-23 2013-09-10 Trascend Medical, Inc. Drug delivery devices and methods
US8343106B2 (en) 2009-12-23 2013-01-01 Alcon Research, Ltd. Ophthalmic valved trocar vent
EP2536433B1 (en) 2010-02-19 2017-08-02 The Regents of The University of California Epithelial membrane protein 2 (emp2) binding reagents and their therapeutic uses in ocular diseases
US8772462B2 (en) 2010-05-26 2014-07-08 Baxter International Inc. Removal of serine proteases by treatment with finely divided silicon dioxide
AU2010202125B1 (en) 2010-05-26 2010-09-02 Takeda Pharmaceutical Company Limited A method to produce an immunoglobulin preparation with improved yield
JP2012020042A (ja) * 2010-07-16 2012-02-02 Japan Imposing Co Ltd 皮下注射針
CN103153316B (zh) 2010-08-05 2015-08-19 弗赛特影像4股份有限公司 组合药物递送方法和设备
EP2627292B1 (en) 2010-10-15 2018-10-10 Clearside Biomedical, Inc. Device for ocular access
US9668915B2 (en) 2010-11-24 2017-06-06 Dose Medical Corporation Drug eluting ocular implant
US10245178B1 (en) 2011-06-07 2019-04-02 Glaukos Corporation Anterior chamber drug-eluting ocular implant
US9102105B2 (en) 2011-09-13 2015-08-11 Vista Scientific Llc Method for forming an ocular drug delivery device
WO2014056895A1 (en) 2012-10-08 2014-04-17 Universität Leipzig A device for a medical treatment of a sclera
EP2916859B1 (en) 2012-11-02 2017-06-28 The U.S.A. as represented by the Secretary, Department of Health and Human Services Method of reducing adverse effects in a cancer patient undergoing treatment with a mek inhibitor
CN104994814B (zh) 2012-11-07 2020-03-24 Ip自由视觉公司 光导眼科用放射装置
WO2014159679A1 (en) 2013-03-12 2014-10-02 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Methods for using lubiprostone to absorb fluid from the subretinal space
AU2013202965B2 (en) 2013-03-15 2016-07-21 Takeda Pharmaceutical Company Limited Improved method for producing factor h from a plasma precipitation fraction
AU2013203048A1 (en) 2013-03-15 2014-10-02 Baxalta GmbH Isolation of factor h from fraction i paste
AU2014259694B2 (en) 2013-05-03 2018-11-08 Clearside Biomedical, Inc. Apparatus and methods for ocular injection
US10010447B2 (en) 2013-12-18 2018-07-03 Novartis Ag Systems and methods for subretinal delivery of therapeutic agents
US9730834B2 (en) 2013-12-20 2017-08-15 Novartis Ag Variable stiffness cannula and methods for a surgical system
US10117578B2 (en) * 2013-12-31 2018-11-06 Ip Liberty Vision Corporation Luminescent ophthalmic device
US10166143B2 (en) 2013-12-31 2019-01-01 Ip Liberty Vision Corporation Versatile light-guided ophthalmic treatment system
PL3104814T3 (pl) 2014-02-12 2021-10-11 Gyroscope Therapeutics Limited Aparat do nadnaczyniówkowego podawania środka leczniczego
CN103919642A (zh) * 2014-03-14 2014-07-16 中国人民解放军第三军医大学第一附属医院 巩膜后注射系统
EP3128966A1 (en) * 2014-04-09 2017-02-15 Universität Leipzig A device for a medical treatment of a sclera
JP6392162B2 (ja) * 2014-05-26 2018-09-19 株式会社スズキプレシオン 注入針装置及び注入器具セット
US20150342875A1 (en) 2014-05-29 2015-12-03 Dose Medical Corporation Implants with controlled drug delivery features and methods of using same
USD760381S1 (en) 2014-06-25 2016-06-28 Donald Fox Orbital injection cannula
WO2016006342A1 (ja) * 2014-07-08 2016-01-14 テルモ株式会社 注射針
US9764122B2 (en) 2014-07-25 2017-09-19 Warsaw Orthopedic, Inc. Drug delivery device and methods having an occluding member
US9775978B2 (en) 2014-07-25 2017-10-03 Warsaw Orthopedic, Inc. Drug delivery device and methods having a retaining member
US10258502B2 (en) 2014-09-18 2019-04-16 Orbit Biomedical Limited Therapeutic agent delivery device
US9867952B2 (en) * 2014-10-07 2018-01-16 N&M Surgical Advancements, LLC Delivery tool of a viscoelastic syringe assembly
EP3081198A1 (en) * 2015-04-14 2016-10-19 Eyevensys Elektroporation device for the eye with a support and with a needle electrode
US11045665B2 (en) 2015-05-06 2021-06-29 Ip Liberty Vision Corporation Light-guided ophthalmic radiation device
US10010502B2 (en) 2015-05-19 2018-07-03 Amorphex Therapeutics Llc Device that delivers a sustained low-dose of a myopia-suppressing drug, while preserving pupillary function and accommodation
US10507134B2 (en) * 2015-05-27 2019-12-17 Novartis Ag Systems and methods for pulsed posterior vitreous detachment creation
WO2017040853A1 (en) 2015-09-02 2017-03-09 Glaukos Corporation Drug delivery implants with bi-directional delivery capacity
US10182939B2 (en) 2015-09-16 2019-01-22 Novartis Ag Hydraulic injector and methods for intra-ocular lens insertion
WO2017053885A1 (en) 2015-09-25 2017-03-30 Glaukos Corporation Punctal implants with controlled drug delivery features and methods of using same
US10076650B2 (en) 2015-11-23 2018-09-18 Warsaw Orthopedic, Inc. Enhanced stylet for drug depot injector
US10478553B2 (en) 2016-03-09 2019-11-19 Orbit Biomedical Limited Apparatus for subretinal administration of therapeutic agent via a curved needle
US11318043B2 (en) 2016-04-20 2022-05-03 Dose Medical Corporation Bioresorbable ocular drug delivery device
WO2017192565A1 (en) 2016-05-02 2017-11-09 Clearside Biomedical, Inc. Systems and methods for ocular drug delivery
USD814637S1 (en) 2016-05-11 2018-04-03 Salutaris Medical Devices, Inc. Brachytherapy device
USD814638S1 (en) 2016-05-11 2018-04-03 Salutaris Medical Devices, Inc. Brachytherapy device
USD815285S1 (en) 2016-05-11 2018-04-10 Salutaris Medical Devices, Inc. Brachytherapy device
USD802755S1 (en) 2016-06-23 2017-11-14 Warsaw Orthopedic, Inc. Drug pellet cartridge
US10973681B2 (en) 2016-08-12 2021-04-13 Clearside Biomedical, Inc. Devices and methods for adjusting the insertion depth of a needle for medicament delivery
USD808529S1 (en) 2016-08-31 2018-01-23 Salutaris Medical Devices, Inc. Holder for a brachytherapy device
USD808528S1 (en) 2016-08-31 2018-01-23 Salutaris Medical Devices, Inc. Holder for a brachytherapy device
US10434261B2 (en) 2016-11-08 2019-10-08 Warsaw Orthopedic, Inc. Drug pellet delivery system and method
KR20230126745A (ko) 2016-12-07 2023-08-30 메이오 파운데이션 포 메디칼 에쥬케이션 앤드 리써치 망막 색소 상피 이식을 위해 피브린 지지체를 사용하는 방법 및 물질
JP7153650B2 (ja) 2016-12-19 2022-10-14 ニュー ワールド メディカル インコーポレイテッド 眼球治療装置、及び関連する使用方法
US11273072B2 (en) 2017-01-13 2022-03-15 Gyroscope Therapeutics Limited Suprachoroidal injection device
US11439772B2 (en) * 2017-03-17 2022-09-13 Jasperate, Inc. Hollow needle for access in non-linear path
DE102017209202A1 (de) * 2017-05-31 2018-12-06 Geuder Ag Vorrichtung zur Präparation eines menschlichen oder tierischen Gewebes für ein Einbringen eines Transplantats oder Implantats
US12285627B2 (en) 2018-10-19 2025-04-29 Colorado School Of Mines Fabrication and irradiation of a radioactive isotope skin patch
KR102729952B1 (ko) * 2019-02-08 2024-11-13 메이오 파운데이션 포 메디칼 에쥬케이션 앤드 리써치 이식 장치
US11850188B2 (en) * 2019-04-01 2023-12-26 Amo Development, Llc Corneal lenticule extraction tool
US20210338481A1 (en) * 2020-04-20 2021-11-04 Bruce B. Becker Lacrimal gland implant for drug delivery and method
US12214160B2 (en) 2021-01-25 2025-02-04 Alcon Inc. Method and apparatus for subretinal injection
CN113041019B (zh) * 2021-03-11 2022-11-22 沈健 一种房角分离器
WO2022240791A1 (en) * 2021-05-10 2022-11-17 Munim Amjad Introducer and/or cannulation needle and methods of making and using the same
EP4346720A4 (en) 2021-05-28 2025-01-01 Sight Sciences, Inc. INTRAOCULAR DEVICES, SYSTEMS AND METHODS
KR20250083528A (ko) * 2022-09-30 2025-06-10 후지필름 셀룰러 다이내믹스, 인코포레이티드 세포 조성물의 전달을 위한 장치 및 방법
WO2024091586A1 (en) * 2022-10-28 2024-05-02 Salutaris Medical Devices, Inc. Radionuclide brachytherapy source systems for ocular radiotherapy
CN121285359A (zh) * 2023-06-22 2026-01-06 爱尔康公司 用于视网膜下递送的方法和设备

Family Cites Families (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3416530A (en) 1966-03-02 1968-12-17 Richard A. Ness Eyeball medication dispensing tablet
US3439675A (en) 1966-06-14 1969-04-22 Becton Dickinson Co Deformable needle assembly
US3828777A (en) 1971-11-08 1974-08-13 Alza Corp Microporous ocular device
US4014335A (en) 1975-04-21 1977-03-29 Alza Corporation Ocular drug delivery device
US4300557A (en) 1980-01-07 1981-11-17 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Method for treating intraocular malignancies
US4327725A (en) 1980-11-25 1982-05-04 Alza Corporation Osmotic device with hydrogel driving member
US4759756A (en) 1984-09-14 1988-07-26 Baxter Travenol Laboratories, Inc. Reconstitution device
DE3672981D1 (de) * 1985-11-27 1990-08-30 Thomas C White Gewebeimplantierbare fluessigkeitsverteileinrichtung.
US5147647A (en) 1986-10-02 1992-09-15 Sohrab Darougar Ocular insert for the fornix
US5322691A (en) 1986-10-02 1994-06-21 Sohrab Darougar Ocular insert with anchoring protrusions
US4759746A (en) * 1987-05-14 1988-07-26 Straus Jeffrey G Retro-bulbar needle
US4853224A (en) 1987-12-22 1989-08-01 Visionex Biodegradable ocular implants
US4997652A (en) 1987-12-22 1991-03-05 Visionex Biodegradable ocular implants
DE3905050A1 (de) 1989-02-18 1990-08-30 Lohmann Therapie Syst Lts Therapeutisches system zur verzoegerten und gesteuerten transdermalen oder transmucosalen verabreichung von wirkstoffen (ii)
US4946450A (en) 1989-04-18 1990-08-07 Biosource Genetics Corporation Glucan/collagen therapeutic eye shields
US5817075A (en) * 1989-08-14 1998-10-06 Photogenesis, Inc. Method for preparation and transplantation of planar implants and surgical instrument therefor
US5164188A (en) 1989-11-22 1992-11-17 Visionex, Inc. Biodegradable ocular implants
US5290892A (en) 1990-11-07 1994-03-01 Nestle S.A. Flexible intraocular lenses made from high refractive index polymers
US5378475A (en) 1991-02-21 1995-01-03 University Of Kentucky Research Foundation Sustained release drug delivery devices
US5167618A (en) * 1991-02-22 1992-12-01 Kershner Robert M Capsulotomy forceps
US5127831A (en) 1991-06-03 1992-07-07 Bab Itai Flexible-end irrigation probe
US5679666A (en) 1991-11-22 1997-10-21 Alcon Laboratories, Inc. Prevention and treatment of ocular neovascularization by treatment with angiostatic steroids
US5770592A (en) 1991-11-22 1998-06-23 Alcon Laboratories, Inc. Prevention and treatment of ocular neovascularization using angiostatic steroids
AU4282793A (en) 1992-04-10 1993-11-18 State Of Oregon Acting By And Through The Oregon State Board Of Higher Education On Behalf Of The Oregon Health Sciences University A microneedle for injection of ocular blood vessels
US5178635A (en) 1992-05-04 1993-01-12 Allergan, Inc. Method for determining amount of medication in an implantable device
FR2690846B1 (fr) 1992-05-05 1995-07-07 Aiache Jean Marc Forme galenique pour administration oculaire et procede de preparation.
AU5092493A (en) 1992-09-08 1994-03-29 Allergan, Inc. Sustained release of ophthalmic drugs from a soluble polymer drug delivery vehicle
WO1995003009A1 (en) 1993-07-22 1995-02-02 Oculex Pharmaceuticals, Inc. Method of treatment of macular degeneration
US5443505A (en) 1993-11-15 1995-08-22 Oculex Pharmaceuticals, Inc. Biocompatible ocular implants
US5516522A (en) 1994-03-14 1996-05-14 Board Of Supervisors Of Louisiana State University Biodegradable porous device for long-term drug delivery with constant rate release and method of making the same
NZ283658A (en) 1994-04-04 1999-09-29 William R Freeman Compositions and treatment of increased intraocular pressure with phosphonyl-alkyloxy-pyrimidines/purines (nucleosides)
US5466233A (en) 1994-04-25 1995-11-14 Escalon Ophthalmics, Inc. Tack for intraocular drug delivery and method for inserting and removing same
AUPM897594A0 (en) 1994-10-25 1994-11-17 Daratech Pty Ltd Controlled release container
ATE232089T1 (de) 1994-11-10 2003-02-15 Univ Kentucky Res Found Implantierbare wiederauffüllbare vorrichtung mit gesteuerter freisetzung zur verabreichung von arzneistoffen unmittelbar an einen inneren teil des körpers
US5725493A (en) * 1994-12-12 1998-03-10 Avery; Robert Logan Intravitreal medicine delivery
WO1996036377A1 (en) 1995-05-14 1996-11-21 Optonol Ltd. Intraocular implant, delivery device, and method of implantation
US5773019A (en) 1995-09-27 1998-06-30 The University Of Kentucky Research Foundation Implantable controlled release device to deliver drugs directly to an internal portion of the body
US5824073A (en) * 1996-03-18 1998-10-20 Peyman; Gholam A. Macular indentor for use in the treatment of subretinal neovascular membranes
US5743274A (en) 1996-03-18 1998-04-28 Peyman; Gholam A. Macular bandage for use in the treatment of subretinal neovascular members
US5904144A (en) 1996-03-22 1999-05-18 Cytotherapeutics, Inc. Method for treating ophthalmic diseases
JP3309175B2 (ja) 1996-03-25 2002-07-29 参天製薬株式会社 タンパク性薬物含有強膜プラグ
US5797898A (en) 1996-07-02 1998-08-25 Massachusetts Institute Of Technology Microchip drug delivery devices
US5665069A (en) 1996-07-19 1997-09-09 Cumer; Patricia Lynn Pressure-directed peribulbar anesthesia delivery device
DE69827138T2 (de) 1997-08-11 2006-02-23 Allergan, Inc., Irvine Steriles Retinoid enthaltendes biodegradierbares Implantat mit verbesserter Biokompatibilität und Verfahren zu dessen Herstellung
US5902598A (en) 1997-08-28 1999-05-11 Control Delivery Systems, Inc. Sustained release drug delivery devices
US6028099A (en) 1998-03-13 2000-02-22 John Hopkins University, School Of Medicine Use of an inhibitor of the protein tyrosine kinase pathway in the treatment of choroidal neovascularization
EP1061913B1 (en) 1998-03-13 2007-06-27 The Johns Hopkins University School Of Medicine The use of a protein tyrosine inhibitor such as genistein in the treatment of diabetic retinopathy
US6309374B1 (en) 1998-08-03 2001-10-30 Insite Vision Incorporated Injection apparatus and method of using same
US6378526B1 (en) 1998-08-03 2002-04-30 Insite Vision, Incorporated Methods of ophthalmic administration
US6135984A (en) 1999-01-06 2000-10-24 Dishler; Jon G. Cannula for use in corrective laser eye surgery

Also Published As

Publication number Publication date
EP1221918A1 (en) 2002-07-17
BR0014930A (pt) 2003-07-15
BR0014930B1 (pt) 2009-01-13
WO2001028473A1 (en) 2001-04-26
TW467740B (en) 2001-12-11
ATE290837T1 (de) 2005-04-15
CA2383572C (en) 2007-12-11
PT1221918E (pt) 2005-06-30
EP1522289A2 (en) 2005-04-13
HK1049438A1 (en) 2003-05-16
MXPA02002376A (es) 2002-08-28
EP1221918B1 (en) 2005-03-16
AU7854800A (en) 2001-04-30
AU775149B2 (en) 2004-07-22
AR039133A2 (es) 2005-02-09
JP2003511204A (ja) 2003-03-25
DE60018777T2 (de) 2006-02-02
DE60018777D1 (de) 2005-04-21
ES2240180T3 (es) 2005-10-16
EP1522289A3 (en) 2008-01-23
US6413245B1 (en) 2002-07-02
HK1049438B (en) 2005-08-26
AR036065A2 (es) 2004-08-11
CA2383572A1 (en) 2001-04-26
AR026075A1 (es) 2002-12-26

Similar Documents

Publication Publication Date Title
AR036065A2 (es) Un metodo para suministrar una droga en el ojo humano
AR039132A2 (es) Metodo para administrar un agente farmaceuticamente activo al ojo teniendo dicho ojo una esclerotica, una capsula de tenon y una macula
AR039130A2 (es) Metodo de administracion de un agente farmaceuticamente activo a un ojo humano
PT1301238E (pt) Agulhas revestidas com vacina
FR12C0067I1 (fr) Implant oculaire biodegradable
ES2166829T3 (es) Composicion acuosa espumante.
WO2006014484A3 (en) Methods and devices for the treatment of ocular conditions
WO2011130639A1 (en) Method and apparatus for treating dilating the ethmoid infundibulum
BR0010869A (pt) Método para administrar um corticosteróide a um segmento posterior de um olho e dispositivo de liberação sustentada implantável
DE60044464D1 (de) Bukkale transmukosale arzneidarreichung unter verwendung einer festen lösung
AR046307A1 (es) Metodo de pretratamiento y sistema para mejorar la administracion transdermica de drogas
ATE195065T1 (de) Biologisch abbaubarer sklerastopfen
AR042917A1 (es) Dispositivo de liberacion sostenida para la administracion ocular de agentes adrenergicos y uso de agentes adrenergicos para su preparacion
WO2003008005A3 (en) Catheter and implants for the delivery of therapeutic agents to tissues
EP1325753A3 (en) Bio-compatible means for controlled drug delivery to tissue and method of use
WO2005063204A3 (en) Drug delivery device with suture ring
CO5210863A1 (es) Medicamento para el tratamiento de urgencia urinaria incre- mentada o incontinencia urinaria . . . . .
SE9901257D0 (sv) Behandling av smärta efter ledoperation
RU2000111751A (ru) Способ лечения кисты молочной железы
WO2002064108A3 (en) Delivery of biologically active agents
DE69614577D1 (de) Polyamin-antagonisten enthaltende intraokulare irrigationslösung
AR024199A1 (es) Uso de la buprenorfina en la preparacion de un disposotivo de suministro transdermico

Legal Events

Date Code Title Description
FB Suspension of granting procedure