ATE232089T1 - Implantierbare wiederauffüllbare vorrichtung mit gesteuerter freisetzung zur verabreichung von arzneistoffen unmittelbar an einen inneren teil des körpers - Google Patents

Implantierbare wiederauffüllbare vorrichtung mit gesteuerter freisetzung zur verabreichung von arzneistoffen unmittelbar an einen inneren teil des körpers

Info

Publication number
ATE232089T1
ATE232089T1 AT95939752T AT95939752T ATE232089T1 AT E232089 T1 ATE232089 T1 AT E232089T1 AT 95939752 T AT95939752 T AT 95939752T AT 95939752 T AT95939752 T AT 95939752T AT E232089 T1 ATE232089 T1 AT E232089T1
Authority
AT
Austria
Prior art keywords
controlled release
internal part
administering drugs
refillable device
release implantable
Prior art date
Application number
AT95939752T
Other languages
English (en)
Inventor
Paul Ashton
Roy A Patchell
Jon Cooper
Byron A Young
Original Assignee
Univ Kentucky Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Kentucky Res Found filed Critical Univ Kentucky Res Found
Application granted granted Critical
Publication of ATE232089T1 publication Critical patent/ATE232089T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0085Brain, e.g. brain implants; Spinal cord
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/02Access sites
    • A61M39/0208Subcutaneous access sites for injecting or removing fluids

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Psychology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Anesthesiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Absorbent Articles And Supports Therefor (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT95939752T 1994-11-10 1995-11-09 Implantierbare wiederauffüllbare vorrichtung mit gesteuerter freisetzung zur verabreichung von arzneistoffen unmittelbar an einen inneren teil des körpers ATE232089T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33924694A 1994-11-10 1994-11-10
PCT/US1995/014319 WO1996014834A1 (en) 1994-11-10 1995-11-09 Implantable refillable controlled release device to deliver drugs directly to an internal portion of the body

Publications (1)

Publication Number Publication Date
ATE232089T1 true ATE232089T1 (de) 2003-02-15

Family

ID=23328150

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95939752T ATE232089T1 (de) 1994-11-10 1995-11-09 Implantierbare wiederauffüllbare vorrichtung mit gesteuerter freisetzung zur verabreichung von arzneistoffen unmittelbar an einen inneren teil des körpers

Country Status (11)

Country Link
US (1) US5836935A (de)
EP (1) EP0788351B1 (de)
JP (1) JP3251294B2 (de)
AT (1) ATE232089T1 (de)
AU (1) AU708529B2 (de)
CA (1) CA2204789C (de)
DE (1) DE69529572T2 (de)
DK (1) DK0788351T3 (de)
ES (1) ES2191719T3 (de)
PT (1) PT788351E (de)
WO (1) WO1996014834A1 (de)

Families Citing this family (312)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6117643A (en) * 1997-11-25 2000-09-12 Ut Battelle, Llc Bioluminescent bioreporter integrated circuit
US6485514B1 (en) * 1997-12-12 2002-11-26 Supergen, Inc. Local delivery of therapeutic agents
US6183461B1 (en) 1998-03-11 2001-02-06 Situs Corporation Method for delivering a medication
US8177762B2 (en) 1998-12-07 2012-05-15 C. R. Bard, Inc. Septum including at least one identifiable feature, access ports including same, and related methods
EP1137451A4 (de) * 1998-12-07 2003-05-21 Std Mfg Inc Implantierbarer gefässzugang
US20010041870A1 (en) * 1999-03-09 2001-11-15 Edward M. Gillis Implantable device for access to a treatment site
WO2000066204A1 (en) * 1999-04-30 2000-11-09 University Of Southern California Implantable microbolus infusion pump
US6139535A (en) * 1999-05-27 2000-10-31 Situs Corporation Method and apparatus for placement and activation of a medical device within a body cavity
US6464628B1 (en) 1999-08-12 2002-10-15 Obtech Medical Ag Mechanical anal incontinence
US6471635B1 (en) 2000-02-10 2002-10-29 Obtech Medical Ag Anal incontinence disease treatment with controlled wireless energy supply
US6416777B1 (en) * 1999-10-21 2002-07-09 Alcon Universal Ltd. Ophthalmic drug delivery device
US7943162B2 (en) * 1999-10-21 2011-05-17 Alcon, Inc. Drug delivery device
DE60040876D1 (de) 1999-10-21 2009-01-02 Alcon Inc Medikamentenzuführeinrichtung
WO2001028473A1 (en) 1999-10-21 2001-04-26 Alcon Universal Ltd. Sub-tenon drug delivery
US6361522B1 (en) 1999-10-21 2002-03-26 Cardiac Pacemakers, Inc. Drug delivery system for implantable cardiac device
US6283949B1 (en) 1999-12-27 2001-09-04 Advanced Cardiovascular Systems, Inc. Refillable implantable drug delivery pump
EP1253880B1 (de) 2000-02-10 2005-09-14 Potencia Medical AG Kontrollierte harninkontinenzbehandlung
DE60135257D1 (de) 2000-02-10 2008-09-18 Potencia Medical Ag Mechanische Vorrichtung zur Impotenzbehandlung
EP1255513B1 (de) 2000-02-14 2005-05-25 Potencia Medical AG Penisprothese
US20090209831A1 (en) * 2000-06-28 2009-08-20 Nexgen Medical Systems, Incorporated Imaging methods for visualizing implanted living cells
US7369890B2 (en) 2000-11-02 2008-05-06 Cardiac Pacemakers, Inc. Technique for discriminating between coordinated and uncoordinated cardiac rhythms
US6409698B1 (en) 2000-11-27 2002-06-25 John N. Robinson Perforate electrodiffusion pump
KR20030005167A (ko) * 2000-11-30 2003-01-17 다이셀 가가꾸 고교 가부시끼가이샤 전사 시트
IL156367A0 (en) * 2000-12-14 2004-01-04 Control Delivery Sys Inc Implantable refillable and ported controlled release drug delivery device
US6689117B2 (en) 2000-12-18 2004-02-10 Cardiac Pacemakers, Inc. Drug delivery system for implantable medical device
DE10105592A1 (de) 2001-02-06 2002-08-08 Achim Goepferich Platzhalter zur Arzneistofffreigabe in der Stirnhöhle
US6726678B1 (en) * 2001-02-22 2004-04-27 Isurgical, Llc Implantable reservoir and system for delivery of a therapeutic agent
US6997914B2 (en) * 2001-04-02 2006-02-14 Horizon Medical Products, Inc. Implantable access port
JP2004536631A (ja) 2001-05-03 2004-12-09 マサチューセッツ・アイ・アンド・イア・インファーマリー 移植可能な薬物送達デバイスおよびその使用
ATE506929T1 (de) 2001-06-12 2011-05-15 Univ Johns Hopkins Med Reservoirvorrichtung für die intraokulare arzneimittelabgabe
US7209783B2 (en) * 2001-06-15 2007-04-24 Cardiac Pacemakers, Inc. Ablation stent for treating atrial fibrillation
US7493162B2 (en) 2001-06-15 2009-02-17 Cardiac Pacemakers, Inc. Pulmonary vein stent for treating atrial fibrillation
PL204644B1 (pl) 2001-07-23 2010-01-29 Alcon Okulistyczne urządzenie do podawania leków
DE60214697T2 (de) * 2001-07-23 2007-09-13 Alcon Inc. Vorrichtung zur freisetzung eines ophthalmischen arzneimittels
WO2003020172A1 (en) * 2001-08-29 2003-03-13 De Carvalho Ricardo A P An implantable and sealable system for unidirectional delivery of therapeutic agents to targeted tissues
US7749528B2 (en) * 2001-08-29 2010-07-06 Ricardo Azevedo Pontes De Carvalho Implantable and sealable medical device for unidirectional delivery of therapeutic agents to tissues
US7340303B2 (en) 2001-09-25 2008-03-04 Cardiac Pacemakers, Inc. Evoked response sensing for ischemia detection
US6758828B2 (en) 2001-12-10 2004-07-06 Regents Of The University Of Minnesota Catheter for cell delivery in tissue
EP1478348A4 (de) * 2002-02-01 2008-06-18 Cleveland Clinic Foundation Mikroinfusionsvorrichtung
WO2003068049A2 (en) * 2002-02-13 2003-08-21 Kuchta, John Controlled cerebrospinal infusion and shunt system
US7236821B2 (en) * 2002-02-19 2007-06-26 Cardiac Pacemakers, Inc. Chronically-implanted device for sensing and therapy
US20030229333A1 (en) * 2002-02-22 2003-12-11 Control Delivery Systems, Inc. Methods for treating otic disorders
AU2003218127B2 (en) * 2002-03-11 2007-07-12 Alcon, Inc. Implantable drug delivery system
US20030176797A1 (en) * 2002-03-12 2003-09-18 Fernando Anzellini Thrombust; implantable delivery system sensible to self diagnosis of acute myocardial infarction for thrombolysis in the first minutes of chest pain
US8926573B2 (en) * 2002-04-02 2015-01-06 Angiodynamics, Inc. Implantable access port
US9636174B2 (en) 2002-04-08 2017-05-02 Medtronic Ardian Luxembourg S.A.R.L. Methods for therapeutic renal neuromodulation
US20140018880A1 (en) 2002-04-08 2014-01-16 Medtronic Ardian Luxembourg S.A.R.L. Methods for monopolar renal neuromodulation
US7617005B2 (en) 2002-04-08 2009-11-10 Ardian, Inc. Methods and apparatus for thermally-induced renal neuromodulation
US7620451B2 (en) 2005-12-29 2009-11-17 Ardian, Inc. Methods and apparatus for pulsed electric field neuromodulation via an intra-to-extravascular approach
US6978174B2 (en) 2002-04-08 2005-12-20 Ardian, Inc. Methods and devices for renal nerve blocking
US7653438B2 (en) 2002-04-08 2010-01-26 Ardian, Inc. Methods and apparatus for renal neuromodulation
US9308043B2 (en) 2002-04-08 2016-04-12 Medtronic Ardian Luxembourg S.A.R.L. Methods for monopolar renal neuromodulation
US7756583B2 (en) 2002-04-08 2010-07-13 Ardian, Inc. Methods and apparatus for intravascularly-induced neuromodulation
US8145316B2 (en) 2002-04-08 2012-03-27 Ardian, Inc. Methods and apparatus for renal neuromodulation
US8774913B2 (en) 2002-04-08 2014-07-08 Medtronic Ardian Luxembourg S.A.R.L. Methods and apparatus for intravasculary-induced neuromodulation
US8131371B2 (en) 2002-04-08 2012-03-06 Ardian, Inc. Methods and apparatus for monopolar renal neuromodulation
US8347891B2 (en) 2002-04-08 2013-01-08 Medtronic Ardian Luxembourg S.A.R.L. Methods and apparatus for performing a non-continuous circumferential treatment of a body lumen
US9308044B2 (en) 2002-04-08 2016-04-12 Medtronic Ardian Luxembourg S.A.R.L. Methods for therapeutic renal neuromodulation
US7853333B2 (en) 2002-04-08 2010-12-14 Ardian, Inc. Methods and apparatus for multi-vessel renal neuromodulation
US8150519B2 (en) 2002-04-08 2012-04-03 Ardian, Inc. Methods and apparatus for bilateral renal neuromodulation
US20060206150A1 (en) 2002-04-08 2006-09-14 Ardian, Inc. Methods and apparatus for treating acute myocardial infarction
US8145317B2 (en) 2002-04-08 2012-03-27 Ardian, Inc. Methods for renal neuromodulation
US20070135875A1 (en) 2002-04-08 2007-06-14 Ardian, Inc. Methods and apparatus for thermally-induced renal neuromodulation
US8774922B2 (en) 2002-04-08 2014-07-08 Medtronic Ardian Luxembourg S.A.R.L. Catheter apparatuses having expandable balloons for renal neuromodulation and associated systems and methods
US20080213331A1 (en) 2002-04-08 2008-09-04 Ardian, Inc. Methods and devices for renal nerve blocking
US20070129761A1 (en) 2002-04-08 2007-06-07 Ardian, Inc. Methods for treating heart arrhythmia
US7162303B2 (en) 2002-04-08 2007-01-09 Ardian, Inc. Renal nerve stimulation method and apparatus for treatment of patients
GB2389791B (en) * 2002-04-30 2006-12-13 Steven Gill Implantable drug delivery pump
US6568177B1 (en) * 2002-06-04 2003-05-27 Ford Global Technologies, Llc Method for rapid catalyst heating
US7089055B2 (en) 2002-06-28 2006-08-08 Cardiac Pacemakers, Inc. Method and apparatus for delivering pre-shock defibrillation therapy
US20070184089A1 (en) * 2002-07-15 2007-08-09 Alcon, Inc. Non-Polymeric Lipophilic Pharmaceutical Implant Compositions for Intraocular Use
ES2295647T3 (es) 2002-07-15 2008-04-16 Alcon, Inc. Composiciones de implante farmaceuticas lipofilas, no polimeras, para uso intraocular.
US8317816B2 (en) 2002-09-30 2012-11-27 Acclarent, Inc. Balloon catheters and methods for treating paranasal sinuses
US20040064110A1 (en) 2002-10-01 2004-04-01 Peter Forsell Injection port
US7615070B2 (en) * 2002-10-11 2009-11-10 Spineco, Inc. Electro-stimulation and medical delivery device
US20040073221A1 (en) 2002-10-11 2004-04-15 Spineco, Inc., A Corporation Of Ohio Electro-stimulation and medical delivery device
US8574204B2 (en) 2002-10-21 2013-11-05 Angiodynamics, Inc. Implantable medical device for improved placement and adherence in the body
US6657038B1 (en) 2002-11-01 2003-12-02 General Electric Company Method for making copolycarbonates
US7072711B2 (en) 2002-11-12 2006-07-04 Cardiac Pacemakers, Inc. Implantable device for delivering cardiac drug therapy
US7627373B2 (en) 2002-11-30 2009-12-01 Cardiac Pacemakers, Inc. Method and apparatus for cell and electrical therapy of living tissue
US7596408B2 (en) 2002-12-09 2009-09-29 Medtronic, Inc. Implantable medical device with anti-infection agent
US20040176818A1 (en) 2002-12-09 2004-09-09 Wahlstrand Carl D. Modular implantable medical device
CA2508124A1 (en) * 2002-12-19 2004-07-08 Alza Corporation Stable, non-aqueous, single-phase gels and formulations thereof for delivery from an implantable device
US7731947B2 (en) * 2003-11-17 2010-06-08 Intarcia Therapeutics, Inc. Composition and dosage form comprising an interferon particle formulation and suspending vehicle
US9445901B2 (en) * 2003-03-12 2016-09-20 Deger C. Tunc Prosthesis with sustained release analgesic
DE602004012081T2 (de) 2003-03-31 2009-03-19 Intarcia Therapeutics, Inc., Emeryville Osmotische pumpe mit mitteln zum ableiten des innendrucks
NZ542867A (en) * 2003-03-31 2009-02-28 Durect Corp Non-aqueous single phase vehicles and formulations utilizing such vehicles involving a polymer
CA2520766A1 (en) * 2003-03-31 2004-10-21 Alza Corporation Osmotic delivery system and method for decreasing start-up times for osmotic delivery systems
US7263401B2 (en) 2003-05-16 2007-08-28 Medtronic, Inc. Implantable medical device with a nonhermetic battery
US7317947B2 (en) 2003-05-16 2008-01-08 Medtronic, Inc. Headset recharger for cranially implantable medical devices
JP2007526019A (ja) * 2003-07-10 2007-09-13 アルコン,インコーポレイティド 眼科用薬物送達デバイス
US7320675B2 (en) 2003-08-21 2008-01-22 Cardiac Pacemakers, Inc. Method and apparatus for modulating cellular metabolism during post-ischemia or heart failure
US8070785B2 (en) 2003-09-16 2011-12-06 Spineco, Inc. Bone anchor prosthesis and system
WO2005032524A2 (en) 2003-09-30 2005-04-14 Alza Corporation Osmotically driven active agent delivery device providing an ascending release profile
US7840263B2 (en) 2004-02-27 2010-11-23 Cardiac Pacemakers, Inc. Method and apparatus for device controlled gene expression
DE602005018174D1 (de) * 2004-03-02 2010-01-21 Infusion Systems Llc Vorrichtung zur automatischen modifizierung des ab
US9089258B2 (en) 2004-04-21 2015-07-28 Acclarent, Inc. Endoscopic methods and devices for transnasal procedures
US7803150B2 (en) 2004-04-21 2010-09-28 Acclarent, Inc. Devices, systems and methods useable for treating sinusitis
US7361168B2 (en) 2004-04-21 2008-04-22 Acclarent, Inc. Implantable device and methods for delivering drugs and other substances to treat sinusitis and other disorders
US20060063973A1 (en) 2004-04-21 2006-03-23 Acclarent, Inc. Methods and apparatus for treating disorders of the ear, nose and throat
US7720521B2 (en) 2004-04-21 2010-05-18 Acclarent, Inc. Methods and devices for performing procedures within the ear, nose, throat and paranasal sinuses
US7559925B2 (en) 2006-09-15 2009-07-14 Acclarent Inc. Methods and devices for facilitating visualization in a surgical environment
US8894614B2 (en) 2004-04-21 2014-11-25 Acclarent, Inc. Devices, systems and methods useable for treating frontal sinusitis
US7410480B2 (en) 2004-04-21 2008-08-12 Acclarent, Inc. Devices and methods for delivering therapeutic substances for the treatment of sinusitis and other disorders
US9554691B2 (en) 2004-04-21 2017-01-31 Acclarent, Inc. Endoscopic methods and devices for transnasal procedures
US9101384B2 (en) 2004-04-21 2015-08-11 Acclarent, Inc. Devices, systems and methods for diagnosing and treating sinusitis and other disorders of the ears, Nose and/or throat
US8764729B2 (en) 2004-04-21 2014-07-01 Acclarent, Inc. Frontal sinus spacer
US7654997B2 (en) 2004-04-21 2010-02-02 Acclarent, Inc. Devices, systems and methods for diagnosing and treating sinusitus and other disorders of the ears, nose and/or throat
US8702626B1 (en) 2004-04-21 2014-04-22 Acclarent, Inc. Guidewires for performing image guided procedures
US20190314620A1 (en) 2004-04-21 2019-10-17 Acclarent, Inc. Apparatus and methods for dilating and modifying ostia of paranasal sinuses and other intranasal or paranasal structures
US9399121B2 (en) 2004-04-21 2016-07-26 Acclarent, Inc. Systems and methods for transnasal dilation of passageways in the ear, nose or throat
US7462175B2 (en) 2004-04-21 2008-12-09 Acclarent, Inc. Devices, systems and methods for treating disorders of the ear, nose and throat
US20070167682A1 (en) 2004-04-21 2007-07-19 Acclarent, Inc. Endoscopic methods and devices for transnasal procedures
US20060004323A1 (en) 2004-04-21 2006-01-05 Exploramed Nc1, Inc. Apparatus and methods for dilating and modifying ostia of paranasal sinuses and other intranasal or paranasal structures
US8932276B1 (en) 2004-04-21 2015-01-13 Acclarent, Inc. Shapeable guide catheters and related methods
US20070208252A1 (en) 2004-04-21 2007-09-06 Acclarent, Inc. Systems and methods for performing image guided procedures within the ear, nose, throat and paranasal sinuses
US8146400B2 (en) 2004-04-21 2012-04-03 Acclarent, Inc. Endoscopic methods and devices for transnasal procedures
US8747389B2 (en) 2004-04-21 2014-06-10 Acclarent, Inc. Systems for treating disorders of the ear, nose and throat
US9351750B2 (en) 2004-04-21 2016-05-31 Acclarent, Inc. Devices and methods for treating maxillary sinus disease
US7419497B2 (en) 2004-04-21 2008-09-02 Acclarent, Inc. Methods for treating ethmoid disease
US8864787B2 (en) 2004-04-21 2014-10-21 Acclarent, Inc. Ethmoidotomy system and implantable spacer devices having therapeutic substance delivery capability for treatment of paranasal sinusitis
US10188413B1 (en) 2004-04-21 2019-01-29 Acclarent, Inc. Deflectable guide catheters and related methods
US7596399B2 (en) 2004-04-29 2009-09-29 Medtronic, Inc Implantation of implantable medical device
US20050245984A1 (en) 2004-04-30 2005-11-03 Medtronic, Inc. Implantable medical device with lubricious material
US20050266087A1 (en) * 2004-05-25 2005-12-01 Gunjan Junnarkar Formulations having increased stability during transition from hydrophobic vehicle to hydrophilic medium
US7764995B2 (en) 2004-06-07 2010-07-27 Cardiac Pacemakers, Inc. Method and apparatus to modulate cellular regeneration post myocardial infarct
US7811266B2 (en) * 2004-07-13 2010-10-12 Std Med, Inc. Volume reducing reservoir insert for an infusion port
FR2873016B1 (fr) * 2004-07-15 2006-09-29 Pierre Marcel Bourgogne Protheses vasculaires artificielles delivrant en permanence des produits actifs empechant toute stenose, thrombose, proliferation cellulaire, etc.. d'acces aise permanent pour toute intervention
EP2583717B1 (de) 2004-07-28 2019-02-20 Medtronic Ardian Luxembourg S.à.r.l. Verfahren und Vorrichtungen für die Nierennervenblockade
US8246569B1 (en) 2004-08-17 2012-08-21 California Institute Of Technology Implantable intraocular pressure drain
US7567841B2 (en) 2004-08-20 2009-07-28 Cardiac Pacemakers, Inc. Method and apparatus for delivering combined electrical and drug therapies
WO2006031397A1 (en) * 2004-09-14 2006-03-23 Spineco, Inc. Implant device
US7937143B2 (en) 2004-11-02 2011-05-03 Ardian, Inc. Methods and apparatus for inducing controlled renal neuromodulation
US7981065B2 (en) 2004-12-20 2011-07-19 Cardiac Pacemakers, Inc. Lead electrode incorporating extracellular matrix
US8874204B2 (en) 2004-12-20 2014-10-28 Cardiac Pacemakers, Inc. Implantable medical devices comprising isolated extracellular matrix
JP2008526461A (ja) * 2005-01-19 2008-07-24 センティネル・グループ・エルエルシー 薬剤送達システム及び方法
CA2594963A1 (en) * 2005-01-24 2006-07-27 Neurosystec Corporation Apparatus and method for delivering therapeutic and/or other agents to the inner ear and to other tissues
US11246913B2 (en) 2005-02-03 2022-02-15 Intarcia Therapeutics, Inc. Suspension formulation comprising an insulinotropic peptide
WO2006083761A2 (en) 2005-02-03 2006-08-10 Alza Corporation Solvent/polymer solutions as suspension vehicles
US8029482B2 (en) 2005-03-04 2011-10-04 C. R. Bard, Inc. Systems and methods for radiographically identifying an access port
US9474888B2 (en) 2005-03-04 2016-10-25 C. R. Bard, Inc. Implantable access port including a sandwiched radiopaque insert
US7947022B2 (en) 2005-03-04 2011-05-24 C. R. Bard, Inc. Access port identification systems and methods
US7785302B2 (en) 2005-03-04 2010-08-31 C. R. Bard, Inc. Access port identification systems and methods
US20110077579A1 (en) * 2005-03-24 2011-03-31 Harrison William V Cochlear implant with localized fluid transport
EP1896117B1 (de) 2005-04-27 2011-01-12 C.R.Bard, Inc. Spritzenpumpesystem zur Injektion von Kontrastmittel in einer intravenösen Leitung
US8147455B2 (en) 2005-04-27 2012-04-03 C. R. Bard, Inc. Infusion apparatuses and methods of use
US10307581B2 (en) 2005-04-27 2019-06-04 C. R. Bard, Inc. Reinforced septum for an implantable medical device
US20060258994A1 (en) * 2005-05-12 2006-11-16 Avery Robert L Implantable delivery device for administering pharmacological agents to an internal portion of a body
US20060280655A1 (en) * 2005-06-08 2006-12-14 California Institute Of Technology Intravascular diagnostic and therapeutic sampling device
US8951225B2 (en) 2005-06-10 2015-02-10 Acclarent, Inc. Catheters with non-removable guide members useable for treatment of sinusitis
US20070073250A1 (en) * 2005-07-08 2007-03-29 Schneiter James A Implantable port
US20070027105A1 (en) * 2005-07-26 2007-02-01 Alza Corporation Peroxide removal from drug delivery vehicle
CN101267779A (zh) 2005-07-27 2008-09-17 福罗里达大学研究基金会有限公司 使用热休克治疗眼睛疾病
US8114113B2 (en) 2005-09-23 2012-02-14 Acclarent, Inc. Multi-conduit balloon catheter
US7790671B2 (en) * 2005-10-07 2010-09-07 Codman & Shurtleff, Inc. Implantable pump for protein delivery for obesity control by drug infusion into the brain
US7616990B2 (en) 2005-10-24 2009-11-10 Cardiac Pacemakers, Inc. Implantable and rechargeable neural stimulator
WO2007064752A2 (en) 2005-11-29 2007-06-07 Smithkline Beecham Corporation Treatment of ocular neovascular disorders such as macular degeneration, angiod streaks, uveitis and macular edema
EP2319558B1 (de) * 2006-03-14 2014-05-21 University Of Southern California Mems-Vorrichtung zur Wirkstofffreisetzung
US9084901B2 (en) 2006-04-28 2015-07-21 Medtronic, Inc. Cranial implant
US8267905B2 (en) 2006-05-01 2012-09-18 Neurosystec Corporation Apparatus and method for delivery of therapeutic and other types of agents
US8190389B2 (en) 2006-05-17 2012-05-29 Acclarent, Inc. Adapter for attaching electromagnetic image guidance components to a medical device
AU2007266475B2 (en) 2006-05-30 2009-12-03 Intarcia Therapeutics, Inc. Two-piece, internal-channel osmotic delivery system flow modulator
US7803148B2 (en) * 2006-06-09 2010-09-28 Neurosystec Corporation Flow-induced delivery from a drug mass
CA2657380A1 (en) * 2006-07-20 2008-01-24 Neurosystec Corporation Devices, systems and methods for ophthalmic drug delivery
JP5048773B2 (ja) 2006-08-09 2012-10-17 インターシア セラピューティクス,インコーポレイティド 浸透圧式デリバリーシステム及びピストンアセンブリー
US9820688B2 (en) 2006-09-15 2017-11-21 Acclarent, Inc. Sinus illumination lightwire device
US9642986B2 (en) 2006-11-08 2017-05-09 C. R. Bard, Inc. Resource information key for an insertable medical device
US9265912B2 (en) 2006-11-08 2016-02-23 C. R. Bard, Inc. Indicia informative of characteristics of insertable medical devices
GB0623395D0 (en) 2006-11-23 2007-01-03 Renishaw Plc Port
US8439687B1 (en) 2006-12-29 2013-05-14 Acclarent, Inc. Apparatus and method for simulated insertion and positioning of guidewares and other interventional devices
US7813811B2 (en) 2007-02-08 2010-10-12 Neuropace, Inc. Refillable reservoir lead systems
US7844345B2 (en) * 2007-02-08 2010-11-30 Neuropace, Inc. Drug eluting lead systems
AU2008244523B2 (en) 2007-04-23 2012-02-16 Intarcia Therapeutics, Inc. Suspension formulations of insulinotropic peptides and uses thereof
US8118757B2 (en) 2007-04-30 2012-02-21 Acclarent, Inc. Methods and devices for ostium measurement
US8485199B2 (en) 2007-05-08 2013-07-16 Acclarent, Inc. Methods and devices for protecting nasal turbinate during surgery
US9265577B2 (en) 2007-05-18 2016-02-23 The Johns Hopkins University Methods and systems for providing planning and dispensation of research and/or treatment for brain disease
EP2164559B1 (de) 2007-06-20 2017-10-25 Medical Components, Inc. Venenzugangsöffnung mit geformten und/oder röntgenopaken indizien
US9610432B2 (en) 2007-07-19 2017-04-04 Innovative Medical Devices, Llc Venous access port assembly with X-ray discernable indicia
MX2010000703A (es) 2007-07-19 2010-07-29 Medical Components Inc Ensamble de puerto de acceso venoso con indicaciones que se distinguen para rayos x.
CA2701644A1 (en) * 2007-10-05 2009-04-09 Angiodynamics, Inc. Dual reservoir implantable access port
EP4681769A3 (de) 2007-10-11 2026-03-18 Implantica Patent Ltd. Vorrichtung zur steuerung des flusses in einem körperorgan
US8696543B2 (en) 2007-10-11 2014-04-15 Kirk Promotion Ltd. Method for controlling flow of intestinal contents in a patient's intestines
US8992409B2 (en) 2007-10-11 2015-03-31 Peter Forsell Method for controlling flow in a bodily organ
US8795153B2 (en) 2007-10-11 2014-08-05 Peter Forsell Method for treating female sexual dysfunction
US9579496B2 (en) 2007-11-07 2017-02-28 C. R. Bard, Inc. Radiopaque and septum-based indicators for a multi-lumen implantable port
US10206821B2 (en) 2007-12-20 2019-02-19 Acclarent, Inc. Eustachian tube dilation balloon with ventilation path
JP5542691B2 (ja) 2007-12-20 2014-07-09 ユニバーシティ オブ サザン カリフォルニア 治療薬を送達するための装置および方法
PL2240220T3 (pl) * 2008-01-03 2016-09-30 Wszczepialne urządzenia do podawania leków i aparaty do napełniania urządzeń
WO2009092067A2 (en) * 2008-01-18 2009-07-23 Neurosystec Corporation Valveless impedance pump drug delivery systems
DK2240155T3 (da) 2008-02-13 2012-09-17 Intarcia Therapeutics Inc Indretninger, formuleringer og fremgangsmåder til levering af flere gavnlige midler
US8182432B2 (en) 2008-03-10 2012-05-22 Acclarent, Inc. Corewire design and construction for medical devices
US9623174B2 (en) * 2008-05-08 2017-04-18 Minipumps, Llc Implantable pumps and cannulas therefor
EP2323716B1 (de) * 2008-05-08 2015-03-04 MiniPumps, LLC Arzneiabgabepumpen
US9849238B2 (en) 2008-05-08 2017-12-26 Minipumps, Llc Drug-delivery pump with intelligent control
CN102202706A (zh) * 2008-05-08 2011-09-28 迷你泵有限责任公司 可植入药物传送装置与用于填充该装置的设备和方法
KR101653180B1 (ko) 2008-07-30 2016-09-01 아클라런트, 인코포레이션 부비 개구 탐지기 장치 및 방법
KR101643907B1 (ko) 2008-09-18 2016-07-29 아클라런트, 인코포레이션 귀, 코 및 인후의 장애를 치료하기 위한 방법 및 장치
EP3120896A1 (de) 2008-10-10 2017-01-25 Kirk Promotion LTD. System, vorrichtung und verfahren zur behandlung einer patientin mit sexueller dysfunktion
WO2010042046A1 (en) 2008-10-10 2010-04-15 Milux Holding S.A. Apparatus, system and operation method for the treatment of female sexual dysfunction
ES2906416T3 (es) 2008-10-31 2022-04-18 Bard Inc C R Sistemas y métodos para identificar una vía de acceso
US9393432B2 (en) 2008-10-31 2016-07-19 Medtronic, Inc. Non-hermetic direct current interconnect
US11890443B2 (en) 2008-11-13 2024-02-06 C. R. Bard, Inc. Implantable medical devices including septum-based indicators
US8932271B2 (en) 2008-11-13 2015-01-13 C. R. Bard, Inc. Implantable medical devices including septum-based indicators
US8652129B2 (en) 2008-12-31 2014-02-18 Medtronic Ardian Luxembourg S.A.R.L. Apparatus, systems, and methods for achieving intravascular, thermally-induced renal neuromodulation
US8623395B2 (en) 2010-01-29 2014-01-07 Forsight Vision4, Inc. Implantable therapeutic device
CN104887389B (zh) 2009-01-29 2017-06-23 弗赛特影像4股份有限公司 后段给药
US20100241155A1 (en) 2009-03-20 2010-09-23 Acclarent, Inc. Guide system with suction
US8435290B2 (en) 2009-03-31 2013-05-07 Acclarent, Inc. System and method for treatment of non-ventilating middle ear by providing a gas pathway through the nasopharynx
US7978742B1 (en) 2010-03-24 2011-07-12 Corning Incorporated Methods for operating diode lasers
US8632511B2 (en) 2009-05-06 2014-01-21 Alcon Research, Ltd. Multiple thermal sensors in a multiple processor environment for temperature control in a drug delivery device
USD629503S1 (en) 2009-05-08 2010-12-21 Sean Caffey Implantable drug-delivery pump
IN2012DN00352A (de) 2009-06-16 2015-08-21 Bikam Pharmaceuticals Inc
US8715244B2 (en) 2009-07-07 2014-05-06 C. R. Bard, Inc. Extensible internal bolster for a medical device
EP2467797B1 (de) 2009-08-18 2017-07-19 MiniPumps, LLC Elektrolytische arzneimittelverabreichungspumpe mit adaptiver steuerung
US20110066072A1 (en) * 2009-09-11 2011-03-17 Drexel University Intracranial pressure sensor
SMT201700583T1 (it) 2009-09-28 2018-01-11 Intarcia Therapeutics Inc Instaurazione e/o terminazione rapida di erogazione di farmaci in modo sostanzialmente stazionario
WO2011039648A1 (en) 2009-09-30 2011-04-07 Glaxo Wellcome Manufacturing Pte Ltd. Methods of administration and treatment
JP2013509422A (ja) 2009-10-30 2013-03-14 シーエヌエス セラピューティクス,インク. 改良されたニュールツリン分子
CN102612343B (zh) 2009-11-17 2015-11-25 C·R·巴德股份有限公司 包括锚定装置和标识部分的包覆模制的进入端口
US8377034B2 (en) 2009-12-04 2013-02-19 Std Med, Inc. Vascular access port
US8177747B2 (en) 2009-12-22 2012-05-15 Alcon Research, Ltd. Method and apparatus for drug delivery
WO2013022801A1 (en) 2011-08-05 2013-02-14 Forsight Vision4, Inc. Small molecule delivery with implantable therapeutic device
GB201002370D0 (en) 2010-02-12 2010-03-31 Renishaw Ireland Ltd Percutaneous drug delivery apparatus
US8038650B2 (en) * 2010-02-22 2011-10-18 Microsert Ltd. Slow release liquid drug delivery device
AU2011248625B2 (en) 2010-04-26 2017-01-05 Pangu Biopharma Limited Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of cysteinyl-tRNA synthetase
CN103096911B (zh) 2010-04-27 2018-05-29 Atyr 医药公司 与异亮氨酰-tRNA合成酶的蛋白片段相关的治疗、诊断和抗体组合物的创新发现
CN103097524B (zh) 2010-04-28 2016-08-03 Atyr医药公司 与丙氨酰-tRNA合成酶的蛋白片段相关的治疗、诊断和抗体组合物的创新发现
CA2797374C (en) 2010-04-29 2021-02-16 Pangu Biopharma Limited Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of asparaginyl trna synthetases
CN103118693B (zh) 2010-04-29 2017-05-03 Atyr 医药公司 与缬氨酰‑tRNA合成酶的蛋白片段相关的治疗、诊断和抗体组合物的创新发现
US9068177B2 (en) 2010-04-29 2015-06-30 Atyr Pharma, Inc Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of glutaminyl-tRNA synthetases
WO2011140135A2 (en) 2010-05-03 2011-11-10 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of methionyl-trna synthetases
CN103096925A (zh) 2010-05-03 2013-05-08 Atyr医药公司 与精氨酰-tRNA合成酶的蛋白片段相关的治疗、诊断和抗体组合物的创新发现
ES2623805T3 (es) 2010-05-03 2017-07-12 Atyr Pharma, Inc. Descubrimiento innovador de composiciones terapéuticas, de diagnóstico y de anticuerpos relacionadas con fragmentos de proteínas de fenilalanil-alfa-ARNt sintetasas
AU2011248101B2 (en) 2010-05-04 2016-10-20 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of p38 multi-tRNA synthetase complex
US8945541B2 (en) 2010-05-14 2015-02-03 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of phenylalanyl-beta-tRNA synthetases
EP2575857B1 (de) 2010-06-01 2018-01-24 aTyr Pharma, Inc. Innovative erkennung therapeutischer, diagnostischer und antikörperhaltiger zusammensetzungen in zusammenhang mit proteinfragmenten von lysyl-trna-synthetasen
CN103118695B (zh) 2010-07-12 2016-08-03 Atyr医药公司 与甘氨酰-tRNA合成酶的蛋白片段相关的治疗、诊断和抗体组合物的发现
US9492315B2 (en) 2010-08-05 2016-11-15 Forsight Vision4, Inc. Implantable therapeutic device
AU2011285548B2 (en) 2010-08-05 2014-02-06 Forsight Vision4, Inc. Combined drug delivery methods and apparatus
ES2888906T3 (es) 2010-08-05 2022-01-10 Forsight Vision4 Inc Aparato inyector para la administración de fármacos
US9029506B2 (en) 2010-08-25 2015-05-12 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of tyrosyl-tRNA synthetases
US9155492B2 (en) 2010-09-24 2015-10-13 Acclarent, Inc. Sinus illumination lightwire device
WO2012061153A1 (en) 2010-10-25 2012-05-10 Medtronic Ardian Luxembourg S.A.R.L. Devices, systems and methods for evaluation and feedback of neuromodulation treatment
US20140031769A1 (en) 2010-11-19 2014-01-30 Forsight Vision4, Inc. Therapeutic agent formulations for implanted devices
USD682416S1 (en) 2010-12-30 2013-05-14 C. R. Bard, Inc. Implantable access port
USD676955S1 (en) 2010-12-30 2013-02-26 C. R. Bard, Inc. Implantable access port
US20120208755A1 (en) 2011-02-16 2012-08-16 Intarcia Therapeutics, Inc. Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers
US10286146B2 (en) 2011-03-14 2019-05-14 Minipumps, Llc Implantable drug pumps and refill devices therefor
US9919099B2 (en) 2011-03-14 2018-03-20 Minipumps, Llc Implantable drug pumps and refill devices therefor
US9603997B2 (en) 2011-03-14 2017-03-28 Minipumps, Llc Implantable drug pumps and refill devices therefor
WO2012131583A2 (en) 2011-03-27 2012-10-04 Microsert Ltd. Miniature implanted drug delivery devices and inserter systems for introducing such devices
WO2012174064A1 (en) 2011-06-14 2012-12-20 Bikam Pharmaceuticals, Inc. Opsin-binding ligands, compositions and methods of use
EP4249059B1 (de) 2011-06-28 2025-07-30 ForSight Vision4, Inc. Vorrichtung zum sammeln einer flüssigkeitsprobe aus einer reservoirkammer einer therapeutischen vorrichtung für das auge
PT2755600T (pt) 2011-09-16 2021-04-19 Forsight Vision4 Inc Aparelhos de troca de fluidos
CA2856703A1 (en) 2011-10-19 2013-04-25 Bikam Pharmaceuticals, Inc. Opsin-binding ligands, compositions and methods of use
US8685106B2 (en) 2011-11-15 2014-04-01 Abraham Lin Method of a pharmaceutical delivery system for use within a joint replacement
AU2012346214B2 (en) 2011-11-30 2017-09-14 Bikam Pharmaceuticals, Inc. Opsin-binding ligands, compositions and methods of use
JP6322142B2 (ja) 2011-12-01 2018-05-09 ビカム ファーマスーティカルス,インコーポレイテッド オプシン結合性リガンド、組成物、及び使用方法
WO2013116061A1 (en) 2012-02-03 2013-08-08 Forsight Vision4, Inc. Insertion and removal methods and apparatus for therapeutic devices
CN104271062B (zh) 2012-03-08 2017-07-07 美敦力Af卢森堡有限责任公司 采用神经调节装置的生物标志物取样和相关系统及方法
WO2013134548A2 (en) 2012-03-08 2013-09-12 Medtronic Ardian Luxembourg S.A.R.L. Ovarian neuromodulation and associated systems and methods
US9707339B2 (en) 2012-03-28 2017-07-18 Angiodynamics, Inc. High flow rate dual reservoir port system
US9713704B2 (en) 2012-03-29 2017-07-25 Bradley D. Chartrand Port reservoir cleaning system and method
US8761717B1 (en) 2012-08-07 2014-06-24 Brian K. Buchheit Safety feature to disable an electronic device when a wireless implantable medical device (IMD) is proximate
GB201217606D0 (en) 2012-10-02 2012-11-14 Renishaw Plc Neurosurgical device and method
US20140110296A1 (en) 2012-10-19 2014-04-24 Medtronic Ardian Luxembourg S.A.R.L. Packaging for Catheter Treatment Devices and Associated Devices, Systems, and Methods
US9205242B2 (en) 2012-11-19 2015-12-08 Angiodynamics, Inc. Port septum with integral valve
CA2897197C (en) 2013-01-15 2022-06-07 The Regents Of The University Of Colorado, A Body Corporate Lacrimal system drug delivery device
EP2968113B8 (de) 2013-03-14 2020-10-28 Forsight Vision4, Inc. Systeme zur verzögerten intraokularen abgabe schwerlöslicher verbindungen aus einem implantat mit einem portabgabesystem
US9629684B2 (en) 2013-03-15 2017-04-25 Acclarent, Inc. Apparatus and method for treatment of ethmoid sinusitis
US9433437B2 (en) 2013-03-15 2016-09-06 Acclarent, Inc. Apparatus and method for treatment of ethmoid sinusitis
EP2978393B1 (de) 2013-03-28 2023-12-27 ForSight Vision4, Inc. Augenimplantat zur abgabe von therapeutischen substanzen
US10166321B2 (en) 2014-01-09 2019-01-01 Angiodynamics, Inc. High-flow port and infusion needle systems
US10194979B1 (en) 2014-03-28 2019-02-05 Medtronic Ardian Luxembourg S.A.R.L. Methods for catheter-based renal neuromodulation
US9980766B1 (en) 2014-03-28 2018-05-29 Medtronic Ardian Luxembourg S.A.R.L. Methods and systems for renal neuromodulation
US10194980B1 (en) 2014-03-28 2019-02-05 Medtronic Ardian Luxembourg S.A.R.L. Methods for catheter-based renal neuromodulation
US9764124B2 (en) 2014-03-31 2017-09-19 Versago Vascular Access, Inc. Vascular access port
US10369345B2 (en) 2014-03-31 2019-08-06 Versago Vascular Access, Inc. Medical access port, systems and methods of use thereof
JP6568200B2 (ja) 2014-04-03 2019-08-28 ヴェルサゴ ヴァスキュラー アクセス インコーポレイテッド ニードルのニードル先端部の取り付け並びに取り外し装置
KR102416726B1 (ko) 2014-07-15 2022-07-05 포사이트 비젼4, 인크. 안구 이식물 전달 디바이스 및 방법
US9474756B2 (en) 2014-08-08 2016-10-25 Forsight Vision4, Inc. Stable and soluble formulations of receptor tyrosine kinase inhibitors, and methods of preparation thereof
US9889085B1 (en) 2014-09-30 2018-02-13 Intarcia Therapeutics, Inc. Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c
US10500091B2 (en) 2014-11-10 2019-12-10 Forsight Vision4, Inc. Expandable drug delivery devices and methods of use
CA2971434A1 (en) 2014-12-18 2016-06-23 Versago Vascular Access, Inc. Devices, systems and methods for removal and replacement of a catheter for an implanted access port
JP6837971B2 (ja) 2014-12-18 2021-03-03 ヴェルサゴ ヴァスキュラー アクセス インコーポレイテッド カテーテル開通性システム及び方法
DE102015100224A1 (de) * 2015-01-09 2016-07-14 Aesculap Ag Implantierbares Medikamentenapplikationssystem
US10925639B2 (en) 2015-06-03 2021-02-23 Intarcia Therapeutics, Inc. Implant placement and removal systems
CA2992455A1 (en) 2015-07-14 2017-01-19 Versago Vascular Access, Inc. Medical access ports, transfer devices and methods of use thereof
KR101693350B1 (ko) * 2015-07-29 2017-01-06 이창윤 체결 구조를 가지는 뇌실 약물 주입 기구
CA3005238A1 (en) 2015-11-20 2017-05-26 Forsight Vision4, Inc. Porous structures for extended release drug delivery devices
CA3006042A1 (en) 2015-11-23 2017-06-01 The Regents Of The University Of Colorado, A Body Corporate Lacrimal system for drug delivery
US11617680B2 (en) 2016-04-05 2023-04-04 Forsight Vision4, Inc. Implantable ocular drug delivery devices
KR20240037175A (ko) 2016-05-16 2024-03-21 인타르시아 세라퓨틱스 인코포레이티드 글루카곤-수용체 선택적 폴리펩티드 및 이들의 이용 방법
WO2017201255A1 (en) * 2016-05-20 2017-11-23 The Regents Of The University Of Colorado, A Body Corporate Lacrimal drug delivery device
USD860451S1 (en) 2016-06-02 2019-09-17 Intarcia Therapeutics, Inc. Implant removal tool
USD840030S1 (en) 2016-06-02 2019-02-05 Intarcia Therapeutics, Inc. Implant placement guide
MX2019008006A (es) 2017-01-03 2019-08-29 Intarcia Therapeutics Inc Metodos que comprenden la administracion continua de un agonista del receptor de glp-1 y la co-administracion de un farmaco.
US10744313B2 (en) 2017-07-27 2020-08-18 University Of Utah Research Foundation Therapeutic delivery device
JP7314155B2 (ja) 2017-11-21 2023-07-25 フォーサイト・ビジョン4・インコーポレーテッド 膨張可能ポート送達システムのための流体交換装置及びその使用方法
WO2019126306A1 (en) 2017-12-21 2019-06-27 Versago Vascular Access, Inc. Medical access ports, transfer devices and methods of use thereof
US10493233B1 (en) * 2018-06-05 2019-12-03 Duke University Bi-directional access to tumors
USD933219S1 (en) 2018-07-13 2021-10-12 Intarcia Therapeutics, Inc. Implant removal tool and assembly
CN110292705A (zh) * 2019-06-27 2019-10-01 山东科技大学 一种远程遥控侧脑室给药系统
BR112022013784A2 (pt) 2020-01-13 2022-10-11 Durect Corp Sistemas de distribuição de fármacos de liberação prolongada com impurezas reduzidas e métodos relacionados
EP4110316A4 (de) 2020-02-26 2024-08-28 Case Western Reserve University Zusammensetzungen und verfahren zur behandlung von fehlgefalteten protein-okular-erkrankungen
RU2748544C1 (ru) * 2020-08-31 2021-05-26 Общество С Ограниченной Ответственностью "Международный Центр Медицинских Исследований И Разработок" (Ооо "Мц Миир") Способ осуществления прицельного малоинвазивного доступа для клеточных трансплантаций в костный регенерат
EP3978065A1 (de) * 2020-10-02 2022-04-06 Heraeus Medical GmbH Implantat zur lokalen wirkstofffreisetzung
US12310928B2 (en) 2020-11-16 2025-05-27 University Of Utah Research Foundation Enthesis healing
CN112472976B (zh) * 2020-11-24 2022-04-01 昆明医科大学 一种治疗脑胶质瘤的双球囊贮液装置
CA3203561A1 (en) 2021-01-12 2022-07-21 Adrian Neil Verity Sustained release drug delivery systems and related methods
USD1033637S1 (en) 2022-01-24 2024-07-02 Forsight Vision4, Inc. Fluid exchange device
WO2024006844A1 (en) * 2022-07-01 2024-01-04 Genentech, Inc. Implantable and refillable drug delivery reservoir system with porous metal frit for sustained intracerebroventricular delivery and methods of use

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3310051A (en) * 1963-12-10 1967-03-21 Rudolf R Schulte Surgical reservoir for implantation beneath the skin
CH557178A (de) * 1972-08-10 1974-12-31 Siemens Ag Geraet fuer die zufuehrung von medikamenten.
GB1567889A (en) * 1977-04-12 1980-05-21 Nippon Kayaku Kk Orally administrable anti-tumour compositions for enhancing absorption of antitumour agent into a gastrointestinal tomour site
DE3138320A1 (de) * 1981-09-25 1983-04-14 Siemens AG, 1000 Berlin und 8000 München Zur implantation in einen lebenden koerper vorgesehenes infusionsgeraet
US4568331A (en) * 1983-10-17 1986-02-04 Marcus Fischer Disposable medicine dispensing device
US4816016A (en) * 1984-03-16 1989-03-28 Pudenz-Schulte Medical Research Corp. Subcutaneous infusion reservoir and pump system
US4761158A (en) * 1984-03-16 1988-08-02 Pudenz-Schulte Medical Research Corp. Subcutaneous infusion reservoir and pump system
US4588394A (en) * 1984-03-16 1986-05-13 Pudenz-Schulte Medical Research Corp. Infusion reservoir and pump system
US4681560A (en) * 1984-03-16 1987-07-21 Pudenz-Schulte Medical Research Corp. Subcutaneous infusion reservoir and pump system
US4687468A (en) * 1984-10-01 1987-08-18 Cook, Incorporated Implantable insulin administration device
IN165717B (de) * 1986-08-07 1989-12-23 Battelle Memorial Institute
US4871352A (en) * 1987-12-07 1989-10-03 Controlled Release Technologies, Inc. Self-regulated therapeutic agent delivery system and method
AU3566989A (en) * 1988-05-16 1989-12-12 Terumo Kabushiki Kaisha Subcutaneously implanted catheter assembly
US4857053A (en) * 1988-08-29 1989-08-15 Dalton Michael J Matrix septum
US5011472A (en) * 1988-09-06 1991-04-30 Brown University Research Foundation Implantable delivery system for biological factors
US4969871A (en) * 1989-02-15 1990-11-13 Alza Corporation Intravenous system for delivering a beneficial agent
US5051257A (en) * 1989-05-09 1991-09-24 Pietronigro Dennis D Antineoplastic solution and method for treating neoplasms
US5139023A (en) * 1989-06-02 1992-08-18 Theratech Inc. Apparatus and method for noninvasive blood glucose monitoring
US5116493A (en) * 1989-08-25 1992-05-26 W. R. Grace & Co.-Conn. Artificial pancreatic perfusion device with reseedable matrix
US5180820A (en) * 1989-08-30 1993-01-19 Barde Yves Alain Brain-derived neurotrophic factor
US5229500A (en) * 1989-08-30 1993-07-20 Regeneron Pharmaceuticals, Inc. Brain derived neurotrophic factor
US5041107A (en) * 1989-10-06 1991-08-20 Cardiac Pacemakers, Inc. Electrically controllable, non-occluding, body implantable drug delivery system
CA2111978A1 (en) * 1991-06-28 1993-01-07 Patrick Aebischer Renewable neural implant device and method

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DE69529572T2 (de) 2003-06-18
DE69529572D1 (de) 2003-03-13
DK0788351T3 (da) 2003-05-26
AU4144996A (en) 1996-06-06
CA2204789A1 (en) 1996-05-23
JP3251294B2 (ja) 2002-01-28
EP0788351A1 (de) 1997-08-13
EP0788351B1 (de) 2003-02-05
JPH10508774A (ja) 1998-09-02
CA2204789C (en) 2002-11-12
ES2191719T3 (es) 2003-09-16
WO1996014834A1 (en) 1996-05-23
EP0788351A4 (de) 1998-03-11
US5836935A (en) 1998-11-17
AU708529B2 (en) 1999-08-05
PT788351E (pt) 2003-06-30

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