AR036204A1 - Proceso para la produccion de quinazolinas y compuestos utiles en dicho proceso - Google Patents
Proceso para la produccion de quinazolinas y compuestos utiles en dicho procesoInfo
- Publication number
- AR036204A1 AR036204A1 ARP020102914A ARP020102914A AR036204A1 AR 036204 A1 AR036204 A1 AR 036204A1 AR P020102914 A ARP020102914 A AR P020102914A AR P020102914 A ARP020102914 A AR P020102914A AR 036204 A1 AR036204 A1 AR 036204A1
- Authority
- AR
- Argentina
- Prior art keywords
- alkyl
- formula
- heteroatom selected
- compound
- alkoxy
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 8
- 238000000034 method Methods 0.000 title abstract 5
- JWVCLYRUEFBMGU-UHFFFAOYSA-N quinazoline Chemical compound N1=CN=CC2=CC=CC=C21 JWVCLYRUEFBMGU-UHFFFAOYSA-N 0.000 title 1
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 6
- 125000005842 heteroatom Chemical group 0.000 abstract 6
- 229910052760 oxygen Inorganic materials 0.000 abstract 6
- 229910052717 sulfur Inorganic materials 0.000 abstract 6
- 125000002373 5 membered heterocyclic group Chemical group 0.000 abstract 5
- 125000004070 6 membered heterocyclic group Chemical group 0.000 abstract 5
- 125000004122 cyclic group Chemical group 0.000 abstract 4
- 125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 3
- 229910052736 halogen Inorganic materials 0.000 abstract 3
- 150000002367 halogens Chemical class 0.000 abstract 3
- 150000003839 salts Chemical class 0.000 abstract 3
- 239000012453 solvate Substances 0.000 abstract 3
- 125000001153 fluoro group Chemical group F* 0.000 abstract 2
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 2
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 125000004191 (C1-C6) alkoxy group Chemical group 0.000 abstract 1
- 125000001963 4 membered heterocyclic group Chemical group 0.000 abstract 1
- 125000003341 7 membered heterocyclic group Chemical group 0.000 abstract 1
- 206010004446 Benign prostatic hyperplasia Diseases 0.000 abstract 1
- 208000004403 Prostatic Hyperplasia Diseases 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/57—Nitriles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Urology & Nephrology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pyridine Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0118752.5A GB0118752D0 (en) | 2001-08-01 | 2001-08-01 | Process for the production of quinazolines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR036204A1 true AR036204A1 (es) | 2004-08-18 |
Family
ID=9919612
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP020102914A AR036204A1 (es) | 2001-08-01 | 2002-07-31 | Proceso para la produccion de quinazolinas y compuestos utiles en dicho proceso |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US7026479B2 (cs) |
| EP (1) | EP1412331B1 (cs) |
| JP (1) | JP2005501054A (cs) |
| KR (1) | KR20040019097A (cs) |
| CN (1) | CN1533378A (cs) |
| AP (1) | AP1299A (cs) |
| AR (1) | AR036204A1 (cs) |
| AT (1) | ATE323677T1 (cs) |
| BR (1) | BR0211670A (cs) |
| CA (1) | CA2451075A1 (cs) |
| CZ (1) | CZ2004151A3 (cs) |
| DE (1) | DE60210778T2 (cs) |
| DO (1) | DOP2002000443A (cs) |
| EG (1) | EG23204A (cs) |
| ES (1) | ES2260457T3 (cs) |
| GB (1) | GB0118752D0 (cs) |
| HN (1) | HN2002000197A (cs) |
| HU (1) | HUP0401573A3 (cs) |
| IL (1) | IL158998A0 (cs) |
| MX (1) | MXPA04000978A (cs) |
| PA (1) | PA8550301A1 (cs) |
| PE (1) | PE20030346A1 (cs) |
| PL (1) | PL368520A1 (cs) |
| RU (1) | RU2261861C1 (cs) |
| UY (1) | UY27399A1 (cs) |
| WO (1) | WO2003011829A1 (cs) |
| ZA (1) | ZA200309043B (cs) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2280003B1 (en) | 2002-07-15 | 2014-04-02 | Symphony Evolution, Inc. | Process for preparing receptor-type kinase modulators |
| EP2392565B1 (en) | 2003-09-26 | 2014-03-19 | Exelixis, Inc. | c-Met modulators and methods of use |
| NZ550796A (en) * | 2004-05-06 | 2010-07-30 | Warner Lambert Co | 4-phenylamino-quinazolin-6-yl-amides |
| RU2450004C2 (ru) * | 2006-08-04 | 2012-05-10 | Мерц Фарма Гмбх Унд Ко. Кгаа | Замещенные пиразолопиримидины, способ их получения и их применение в качестве лекарственного средства |
| RS52754B2 (sr) | 2009-01-16 | 2022-08-31 | Exelixis Inc | Malat so n-(4- {[6,7-bis(metiloksi)hinolin-4-il]oksi}fenil-n'- (4-fluorofenil) ciklopropan-1,1-dikarboksamid-a, i njeni kristalni oblici za lečenje karcinoma |
| KR101913109B1 (ko) | 2009-03-18 | 2018-10-31 | 리스버로직스 코퍼레이션 | 신규한 소염제 |
| IN2012DN00352A (cs) * | 2009-06-16 | 2015-08-21 | Bikam Pharmaceuticals Inc | |
| UA108618C2 (uk) | 2009-08-07 | 2015-05-25 | Застосування c-met-модуляторів в комбінації з темозоломідом та/або променевою терапією для лікування раку | |
| JP6126118B2 (ja) * | 2011-11-30 | 2017-05-10 | ビカム ファーマスーティカルス，インコーポレイテッド | オプシン結合性リガンド、組成物、及び使用方法 |
| KR101532570B1 (ko) * | 2012-10-15 | 2015-06-30 | 리스버로직스 코퍼레이션 | 벤즈아미드 화합물의 합성에 유용한 화합물 |
| JP6903585B2 (ja) | 2015-03-13 | 2021-07-14 | レスバーロジックス コーポレイション | 補体関連疾患の治療のための組成物および治療方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8719378D0 (en) * | 1987-08-15 | 1987-09-23 | Pfizer Ltd | Antiarrythmic agents |
| WO1998030562A1 (en) * | 1997-01-09 | 1998-07-16 | Terumo Kabushiki Kaisha | Novel amide derivatives and intermediates for the synthesis thereof |
| GB9700504D0 (en) * | 1997-01-11 | 1997-02-26 | Pfizer Ltd | Pharmaceutical compounds |
-
2001
- 2001-08-01 GB GBGB0118752.5A patent/GB0118752D0/en not_active Ceased
-
2002
- 2002-07-11 PA PA20028550301A patent/PA8550301A1/es unknown
- 2002-07-19 WO PCT/IB2002/002872 patent/WO2003011829A1/en not_active Ceased
- 2002-07-19 ES ES02745749T patent/ES2260457T3/es not_active Expired - Lifetime
- 2002-07-19 PL PL02368520A patent/PL368520A1/xx not_active Application Discontinuation
- 2002-07-19 MX MXPA04000978A patent/MXPA04000978A/es active IP Right Grant
- 2002-07-19 KR KR10-2004-7001513A patent/KR20040019097A/ko not_active Ceased
- 2002-07-19 CA CA002451075A patent/CA2451075A1/en not_active Abandoned
- 2002-07-19 AT AT02745749T patent/ATE323677T1/de not_active IP Right Cessation
- 2002-07-19 RU RU2004102692/04A patent/RU2261861C1/ru not_active IP Right Cessation
- 2002-07-19 HU HU0401573A patent/HUP0401573A3/hu unknown
- 2002-07-19 DE DE60210778T patent/DE60210778T2/de not_active Expired - Fee Related
- 2002-07-19 BR BR0211670-7A patent/BR0211670A/pt not_active IP Right Cessation
- 2002-07-19 CN CNA028143256A patent/CN1533378A/zh active Pending
- 2002-07-19 CZ CZ2004151A patent/CZ2004151A3/cs unknown
- 2002-07-19 JP JP2003517021A patent/JP2005501054A/ja active Pending
- 2002-07-19 US US10/199,755 patent/US7026479B2/en not_active Expired - Fee Related
- 2002-07-19 IL IL15899802A patent/IL158998A0/xx unknown
- 2002-07-19 EP EP02745749A patent/EP1412331B1/en not_active Expired - Lifetime
- 2002-07-23 DO DO2002000443A patent/DOP2002000443A/es unknown
- 2002-07-26 PE PE2002000678A patent/PE20030346A1/es not_active Application Discontinuation
- 2002-07-29 HN HN2002000197A patent/HN2002000197A/es unknown
- 2002-07-29 UY UY27399A patent/UY27399A1/es not_active Application Discontinuation
- 2002-07-29 EG EG2002070853A patent/EG23204A/xx active
- 2002-07-31 AR ARP020102914A patent/AR036204A1/es unknown
- 2002-08-01 AP APAP/P/2002/002602A patent/AP1299A/en active
-
2003
- 2003-11-20 ZA ZA200309043A patent/ZA200309043B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PL368520A1 (en) | 2005-04-04 |
| ATE323677T1 (de) | 2006-05-15 |
| JP2005501054A (ja) | 2005-01-13 |
| MXPA04000978A (es) | 2004-04-20 |
| AP1299A (en) | 2004-09-06 |
| AP2002002602A0 (en) | 2002-09-30 |
| DE60210778D1 (de) | 2006-05-24 |
| CN1533378A (zh) | 2004-09-29 |
| EP1412331A1 (en) | 2004-04-28 |
| WO2003011829A1 (en) | 2003-02-13 |
| US20030100753A1 (en) | 2003-05-29 |
| CA2451075A1 (en) | 2003-02-13 |
| DOP2002000443A (es) | 2003-02-15 |
| GB0118752D0 (en) | 2001-09-26 |
| EG23204A (en) | 2004-07-31 |
| KR20040019097A (ko) | 2004-03-04 |
| DE60210778T2 (de) | 2007-01-04 |
| BR0211670A (pt) | 2004-07-13 |
| HUP0401573A3 (en) | 2005-06-28 |
| HN2002000197A (es) | 2003-02-27 |
| IL158998A0 (en) | 2004-05-12 |
| CZ2004151A3 (cs) | 2005-01-12 |
| PA8550301A1 (es) | 2003-09-05 |
| PE20030346A1 (es) | 2003-04-05 |
| RU2261861C1 (ru) | 2005-10-10 |
| ES2260457T3 (es) | 2006-11-01 |
| ZA200309043B (en) | 2004-11-22 |
| HUP0401573A2 (hu) | 2005-01-28 |
| US7026479B2 (en) | 2006-04-11 |
| RU2004102692A (ru) | 2005-07-10 |
| UY27399A1 (es) | 2003-02-28 |
| EP1412331B1 (en) | 2006-04-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |