AR052155A1 - Compuestos organicos - Google Patents
Compuestos organicosInfo
- Publication number
- AR052155A1 AR052155A1 ARP050105195A ARP050105195A AR052155A1 AR 052155 A1 AR052155 A1 AR 052155A1 AR P050105195 A ARP050105195 A AR P050105195A AR P050105195 A ARP050105195 A AR P050105195A AR 052155 A1 AR052155 A1 AR 052155A1
- Authority
- AR
- Argentina
- Prior art keywords
- pharmaceutically acceptable
- water
- insoluble
- animal
- human
- Prior art date
Links
- 150000002894 organic compounds Chemical class 0.000 title 1
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 abstract 6
- 229920001169 thermoplastic Polymers 0.000 abstract 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- 241001465754 Metazoa Species 0.000 abstract 2
- 239000013543 active substance Substances 0.000 abstract 2
- 239000002671 adjuvant Substances 0.000 abstract 2
- 239000007943 implant Substances 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 206010072064 Exposure to body fluid Diseases 0.000 abstract 1
- 239000012736 aqueous medium Substances 0.000 abstract 1
- 230000000975 bioactive effect Effects 0.000 abstract 1
- 210000001124 body fluid Anatomy 0.000 abstract 1
- 239000010839 body fluid Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 238000013270 controlled release Methods 0.000 abstract 1
- 238000012377 drug delivery Methods 0.000 abstract 1
- 238000011065 in-situ storage Methods 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 239000004416 thermosoftening plastic Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
Composicion que comprende un polímero termoplástico, un agente modificador de la velocidad y un agente biologicamente activo, util como implante de administracion de fármacos de liberacion lenta en el cuerpo de un ser humano o animal que se puede administrar en forma líquida en el cuerpo. Reivindicacion 1: Una composicion para formar un implante in situ dentro del cuerpo mediante la exposicion a los fluidos corporales, adecuada para una liberacion controlada del material bioactivo, que comprende un polímero termoplástico, biodegradable, farmacéuticamente aceptable, que es insoluble en un medio acuoso o en los fluidos corporales de un ser humano o animal, un solvente orgánico biodegradable, insoluble en agua o apenas soluble en agua, farmacéuticamente aceptable, un adyuvante biocompatible soluble en agua y farmacéuticamente aceptable y un agente biologicamente activo, caracterizado porque la cantidad en peso de dicho solvente es superior a la de dicho polímero termoplástico y porque el adyuvante se selecciona del grupo que comprende etanol, glicerol y glicerol formal.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP04029498 | 2004-12-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR052155A1 true AR052155A1 (es) | 2007-03-07 |
Family
ID=34927750
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP050105195A AR052155A1 (es) | 2004-12-14 | 2005-12-12 | Compuestos organicos |
Country Status (16)
| Country | Link |
|---|---|
| JP (1) | JP5372378B2 (es) |
| KR (1) | KR101304160B1 (es) |
| CN (1) | CN101056617B (es) |
| AR (1) | AR052155A1 (es) |
| AT (1) | ATE389386T1 (es) |
| AU (1) | AU2005315823B2 (es) |
| BR (1) | BRPI0519022A2 (es) |
| CA (1) | CA2585779C (es) |
| DE (1) | DE602005005522T2 (es) |
| ES (1) | ES2301084T3 (es) |
| MX (1) | MX2007007099A (es) |
| NZ (1) | NZ554904A (es) |
| RU (1) | RU2394558C2 (es) |
| TW (1) | TWI369218B (es) |
| WO (1) | WO2006063794A1 (es) |
| ZA (1) | ZA200703506B (es) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8852638B2 (en) | 2005-09-30 | 2014-10-07 | Durect Corporation | Sustained release small molecule drug formulation |
| ES2562878T3 (es) | 2007-05-25 | 2016-03-08 | Indivior Uk Limited | Formulaciones de liberación sostenida de compuestos de risperidona |
| CN101159064B (zh) | 2007-11-29 | 2010-09-01 | 腾讯科技（深圳）有限公司 | 画像生成系统以及按照图像生成画像的方法 |
| US10588855B2 (en) | 2008-05-12 | 2020-03-17 | University Of Utah Research Foundation | Intraocular drug delivery device and associated methods |
| US9877973B2 (en) | 2008-05-12 | 2018-01-30 | University Of Utah Research Foundation | Intraocular drug delivery device and associated methods |
| US10064819B2 (en) | 2008-05-12 | 2018-09-04 | University Of Utah Research Foundation | Intraocular drug delivery device and associated methods |
| JP6543431B2 (ja) * | 2013-10-10 | 2019-07-10 | ユニバーシティー オブ ユタ リサーチ ファウンデーションＵｎｉｖｅｒｓｉｔｙ ｏｆ Ｕｔａｈ Ｒｅｓｅａｒｃｈ Ｆｏｕｎｄａｔｉｏｎ | 眼内薬物送達デバイスおよび付随する方法 |
| HUE065367T2 (hu) * | 2017-04-13 | 2024-05-28 | Ceva Sante Animale | Parazitafertõzések kezelésére használható injektálható anyag |
| CN112336682B (zh) * | 2020-09-28 | 2022-07-08 | 浙江大学 | 具有缓控释药物作用的可注射复合载体与组合物及制备方法 |
| WO2024003291A1 (en) | 2022-06-30 | 2024-01-04 | Virbac | Deslorelin use in chemical castration of a non-human mammal related to pk/pd interaction |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4938763B1 (en) * | 1988-10-03 | 1995-07-04 | Atrix Lab Inc | Biodegradable in-situ forming implants and method of producing the same |
| US5324519A (en) * | 1989-07-24 | 1994-06-28 | Atrix Laboratories, Inc. | Biodegradable polymer composition |
| JP4642946B2 (ja) * | 1996-12-20 | 2011-03-02 | アルザ コーポレイション | ゲル組成物および方法 |
| BR9907968B1 (pt) * | 1998-02-23 | 2009-12-01 | composição de polìmeros com memória de formato biodegradáveis e artigos compreendendo a mesma. | |
| PT1063942E (pt) * | 1998-03-19 | 2004-10-29 | Merck & Co Inc | Composicoes polimericas liquidas para libertacao controlada de substancias bioactivas |
| US7128927B1 (en) * | 1998-04-14 | 2006-10-31 | Qlt Usa, Inc. | Emulsions for in-situ delivery systems |
| JP4317606B2 (ja) * | 1998-09-18 | 2009-08-19 | サンスター株式会社 | 固体粒子形成用組成物 |
| RU2355385C2 (ru) * | 2002-11-06 | 2009-05-20 | Алза Корпорейшн | Композиции пролонгированного действия с контролируемым высвобождением |
| JP2007525429A (ja) * | 2003-03-11 | 2007-09-06 | キューエルティー ユーエスエー，インコーポレイテッド． | 細胞スケジュール依存性抗癌剤のための処方 |
-
2005
- 2005-12-12 TW TW094143807A patent/TWI369218B/zh not_active IP Right Cessation
- 2005-12-12 AR ARP050105195A patent/AR052155A1/es unknown
- 2005-12-13 CN CN2005800386792A patent/CN101056617B/zh not_active Expired - Fee Related
- 2005-12-13 WO PCT/EP2005/013377 patent/WO2006063794A1/en not_active Ceased
- 2005-12-13 NZ NZ554904A patent/NZ554904A/en not_active IP Right Cessation
- 2005-12-13 ES ES05815330T patent/ES2301084T3/es not_active Expired - Lifetime
- 2005-12-13 JP JP2007545931A patent/JP5372378B2/ja not_active Expired - Fee Related
- 2005-12-13 RU RU2007126759/15A patent/RU2394558C2/ru not_active IP Right Cessation
- 2005-12-13 AT AT05815330T patent/ATE389386T1/de not_active IP Right Cessation
- 2005-12-13 CA CA2585779A patent/CA2585779C/en not_active Expired - Fee Related
- 2005-12-13 DE DE602005005522T patent/DE602005005522T2/de not_active Expired - Lifetime
- 2005-12-13 AU AU2005315823A patent/AU2005315823B2/en not_active Ceased
- 2005-12-13 BR BRPI0519022-3A patent/BRPI0519022A2/pt not_active IP Right Cessation
- 2005-12-13 MX MX2007007099A patent/MX2007007099A/es active IP Right Grant
- 2005-12-13 KR KR1020077013264A patent/KR101304160B1/ko not_active Expired - Fee Related
-
2007
- 2007-05-02 ZA ZA200703506A patent/ZA200703506B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ZA200703506B (en) | 2008-09-25 |
| DE602005005522D1 (de) | 2008-04-30 |
| JP5372378B2 (ja) | 2013-12-18 |
| DE602005005522T2 (de) | 2009-04-16 |
| ATE389386T1 (de) | 2008-04-15 |
| AU2005315823B2 (en) | 2009-06-04 |
| TW200635616A (en) | 2006-10-16 |
| NZ554904A (en) | 2009-11-27 |
| RU2007126759A (ru) | 2009-01-27 |
| RU2394558C2 (ru) | 2010-07-20 |
| CA2585779A1 (en) | 2006-06-22 |
| TWI369218B (en) | 2012-08-01 |
| CA2585779C (en) | 2014-01-28 |
| JP2008523131A (ja) | 2008-07-03 |
| WO2006063794A1 (en) | 2006-06-22 |
| MX2007007099A (es) | 2007-06-22 |
| CN101056617B (zh) | 2012-07-11 |
| KR20070092964A (ko) | 2007-09-14 |
| BRPI0519022A2 (pt) | 2008-12-23 |
| ES2301084T3 (es) | 2008-06-16 |
| KR101304160B1 (ko) | 2013-09-04 |
| CN101056617A (zh) | 2007-10-17 |
| AU2005315823A1 (en) | 2006-06-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |