AR073923A1 - Pirido( 4,3-b) indoles que contienen restos rigidos - Google Patents

Pirido( 4,3-b) indoles que contienen restos rigidos

Info

Publication number: AR073923A1
Authority: AR; Argentina
Prior art keywords: substituted; unsubstituted; independently; halo; alkoxy
Prior art date: 2008-10-31

Application number

ARP090104220A

Other languages

English (en)

Spanish (es)

Inventor

Rajendra Parasmal Jain

Sarvajit Chakravarty

David T Hung

Andrew Asher Protter

David T Ung

Marco Giorgetti

Andrew Ahser Protter

Original Assignee

Medivation Technologies Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2008-10-31

Filing date

2009-10-30

Publication date

2010-12-09

2009-10-30 Application filed by Medivation Technologies Inc filed Critical Medivation Technologies Inc

2010-12-09 Publication of AR073923A1 publication Critical patent/AR073923A1/es

Links

150000002475 indoles Chemical class 0.000 title 1
-1 perhaloalkyl Chemical group 0.000 abstract 10
125000004209 (C1-C8) alkyl group Chemical group 0.000 abstract 7
125000003545 alkoxy group Chemical group 0.000 abstract 7
125000001475 halogen functional group Chemical group 0.000 abstract 7
125000000753 cycloalkyl group Chemical group 0.000 abstract 6
125000001072 heteroaryl group Chemical group 0.000 abstract 6
125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 5
125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 5
125000004648 C2-C8 alkenyl group Chemical group 0.000 abstract 4
OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical group [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 4
125000004442 acylamino group Chemical group 0.000 abstract 4
125000003118 aryl group Chemical group 0.000 abstract 4
229910052799 carbon Inorganic materials 0.000 abstract 4
125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 4
125000005102 carbonylalkoxy group Chemical group 0.000 abstract 4
125000004093 cyano group Chemical group *C#N 0.000 abstract 4
125000000623 heterocyclic group Chemical group 0.000 abstract 4
125000004423 acyloxy group Chemical group 0.000 abstract 3
125000000266 alpha-aminoacyl group Chemical group 0.000 abstract 3
150000001875 compounds Chemical class 0.000 abstract 3
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 3
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 3
125000006552 (C3-C8) cycloalkyl group Chemical group 0.000 abstract 2
125000002252 acyl group Chemical group 0.000 abstract 2
125000000304 alkynyl group Chemical group 0.000 abstract 2
125000003710 aryl alkyl group Chemical group 0.000 abstract 2
125000004104 aryloxy group Chemical group 0.000 abstract 2
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
229910052739 hydrogen Inorganic materials 0.000 abstract 2
239000001257 hydrogen Substances 0.000 abstract 2
125000003107 substituted aryl group Chemical group 0.000 abstract 2
125000004001 thioalkyl group Chemical group 0.000 abstract 2
150000003573 thiols Chemical class 0.000 abstract 2
125000004649 C2-C8 alkynyl group Chemical group 0.000 abstract 1
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
208000028017 Psychotic disease Diseases 0.000 abstract 1
125000005121 aminocarbonylalkoxy group Chemical group 0.000 abstract 1
208000010877 cognitive disease Diseases 0.000 abstract 1
125000000392 cycloalkenyl group Chemical group 0.000 abstract 1
150000002431 hydrogen Chemical group 0.000 abstract 1
230000001404 mediated effect Effects 0.000 abstract 1
230000001537 neural effect Effects 0.000 abstract 1
239000002858 neurotransmitter agent Substances 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
239000012453 solvate Substances 0.000 abstract 1
230000001225 therapeutic effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Psychiatry (AREA)
Hospice & Palliative Care (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

ARP090104220A 2008-10-31 2009-10-30 Pirido( 4,3-b) indoles que contienen restos rigidos AR073923A1 (es)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date
US11051908P	2008-10-31	2008-10-31
US17396009P	2009-04-29	2009-04-29
US24515009P	2009-09-23	2009-09-23

Publications (1)

Publication Number	Publication Date
AR073923A1 true AR073923A1 (es)	2010-12-09

Family

ID=42129313

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ARP090104220A AR073923A1 (es)	2008-10-31	2009-10-30	Pirido( 4,3-b) indoles que contienen restos rigidos

Country Status (10)

Country	Link
US (3)	US8907097B2 (2)
EP (1)	EP2346332A4 (2)
JP (2)	JP5588991B2 (2)
CN (1)	CN102271508B (2)
AR (1)	AR073923A1 (2)
AU (1)	AU2009308706C1 (2)
BR (1)	BRPI0919948A2 (2)
CA (1)	CA2742320A1 (2)
TW (1)	TWI477503B (2)
WO (1)	WO2010051501A1 (2)

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2009
- 2009-10-30 AU AU2009308706A patent/AU2009308706C1/en not_active Ceased
- 2009-10-30 WO PCT/US2009/062869 patent/WO2010051501A1/en not_active Ceased
- 2009-10-30 EP EP09824199A patent/EP2346332A4/en not_active Withdrawn
- 2009-10-30 CN CN200980153434.2A patent/CN102271508B/zh not_active Expired - Fee Related
- 2009-10-30 AR ARP090104220A patent/AR073923A1/es unknown
- 2009-10-30 CA CA2742320A patent/CA2742320A1/en not_active Abandoned
- 2009-10-30 BR BRPI0919948-9A patent/BRPI0919948A2/pt not_active IP Right Cessation
- 2009-10-30 JP JP2011534826A patent/JP5588991B2/ja not_active Expired - Fee Related
- 2009-10-30 US US12/610,217 patent/US8907097B2/en not_active Expired - Fee Related
- 2009-10-30 TW TW098137048A patent/TWI477503B/zh not_active IP Right Cessation
2013
- 2013-03-08 US US13/791,544 patent/US8906925B2/en not_active Expired - Fee Related
2014
- 2014-04-21 JP JP2014087277A patent/JP2014133759A/ja not_active Withdrawn
- 2014-11-03 US US14/531,915 patent/US9458155B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
EP2346332A1 (en)	2011-07-27
AU2009308706C1 (en)	2016-01-21
US20150051218A1 (en)	2015-02-19
AU2009308706B2 (en)	2015-09-03
JP2012507566A (ja)	2012-03-29
JP2014133759A (ja)	2014-07-24
TW201022264A (en)	2010-06-16
US8906925B2 (en)	2014-12-09
AU2009308706A1 (en)	2010-05-06
HK1164057A1 (en)	2012-09-21
EP2346332A4 (en)	2012-08-08
CN102271508A (zh)	2011-12-07
CN102271508B (zh)	2015-04-29
WO2010051501A1 (en)	2010-05-06
US9458155B2 (en)	2016-10-04
JP5588991B2 (ja)	2014-09-10
US20100216814A1 (en)	2010-08-26
US8907097B2 (en)	2014-12-09
US20130190322A1 (en)	2013-07-25
BRPI0919948A2 (pt)	2015-08-25
CA2742320A1 (en)	2010-05-06
TWI477503B (zh)	2015-03-21

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