AR080466A1 - Enriquecimiento selectivo de anticuerpos - Google Patents

Enriquecimiento selectivo de anticuerpos

Info

Publication number
AR080466A1
AR080466A1 ARP110100705A ARP110100705A AR080466A1 AR 080466 A1 AR080466 A1 AR 080466A1 AR P110100705 A ARP110100705 A AR P110100705A AR P110100705 A ARP110100705 A AR P110100705A AR 080466 A1 AR080466 A1 AR 080466A1
Authority
AR
Argentina
Prior art keywords
binding
selective enrichment
antibodies
protein
target protein
Prior art date
Application number
ARP110100705A
Other languages
English (en)
Inventor
Philine Dobberthien
Maria-Katharina Hoyer
Michael Dieterle
Dorothee Ambrosius
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of AR080466A1 publication Critical patent/AR080466A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/30—Extraction; Separation; Purification by precipitation
    • C07K1/32—Extraction; Separation; Purification by precipitation as complexes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
    • C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Un procedimiento para el enriquecimiento selectivo de inmunoglobulinas u otras proteínas que contienen un dominio Fc (proteína diana), con las etapas: e. proporcionar una solucion que contiene la proteína diana; f. incorporar una proteína de union de Fc con exactamente dos sitios de union en condiciones que posibilitan una union; g. separar el precipitado de la fase líquida; h. liberar la union de la proteína diana con la proteína de union de Fc.
ARP110100705A 2010-03-05 2011-03-04 Enriquecimiento selectivo de anticuerpos AR080466A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP10155647 2010-03-05

Publications (1)

Publication Number Publication Date
AR080466A1 true AR080466A1 (es) 2012-04-11

Family

ID=42470646

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP110100705A AR080466A1 (es) 2010-03-05 2011-03-04 Enriquecimiento selectivo de anticuerpos

Country Status (11)

Country Link
US (3) US20120071637A1 (es)
EP (1) EP2542567B1 (es)
JP (1) JP5917417B2 (es)
KR (1) KR101855714B1 (es)
CN (1) CN102791728B (es)
AR (1) AR080466A1 (es)
AU (1) AU2011222991B2 (es)
CA (1) CA2791918C (es)
SG (1) SG183920A1 (es)
TW (1) TW201144325A (es)
WO (1) WO2011107518A1 (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11566082B2 (en) 2014-11-17 2023-01-31 Cytiva Bioprocess R&D Ab Mutated immunoglobulin-binding polypeptides
CN106084062B (zh) * 2015-04-28 2021-04-02 荣昌生物制药（烟台）有限公司 桥连的双特异性融合蛋白
DK3455244T3 (da) * 2016-05-11 2022-06-07 Cytiva Bioprocess R & D Ab Muterede immunoglobulin-bindende polypeptider
US10513537B2 (en) 2016-05-11 2019-12-24 Ge Healthcare Bioprocess R&D Ab Separation matrix
WO2017194592A1 (en) 2016-05-11 2017-11-16 Ge Healthcare Bioprocess R&D Ab Method of storing a separation matrix
US10654887B2 (en) 2016-05-11 2020-05-19 Ge Healthcare Bio-Process R&D Ab Separation matrix
WO2017194593A1 (en) 2016-05-11 2017-11-16 Ge Healthcare Bioprocess R&D Ab Method of cleaning and/or sanitizing a separation matrix
US10703774B2 (en) 2016-09-30 2020-07-07 Ge Healthcare Bioprocess R&D Ab Separation method
US10889615B2 (en) 2016-05-11 2021-01-12 Cytiva Bioprocess R&D Ab Mutated immunoglobulin-binding polypeptides
US10730908B2 (en) 2016-05-11 2020-08-04 Ge Healthcare Bioprocess R&D Ab Separation method
JP7031934B2 (ja) 2016-05-11 2022-03-08 サイティバ・バイオプロセス・アールアンドディ・アクチボラグ 分離マトリックス
US12448411B2 (en) 2016-09-30 2025-10-21 Cytiva Bioprocess R&D Ab Separation method
EP3604341A4 (en) * 2017-03-31 2020-12-09 Kaneka Corporation AFFINITY DISSOCIATION MATRIX FOR IMMUNOLOGICAL PURIFICATION PURPOSES
EP3823994A4 (en) * 2018-07-19 2022-04-20 Ab Studio Inc. Novel systems for screening internalizing antibody and uses thereof
WO2019160397A2 (ko) 2019-05-09 2019-08-22 엘지전자 주식회사 세탁물 처리장치 및 세탁물 처리방법

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2096953A1 (en) * 1990-11-26 1992-05-27 Anthony Atkinson Immunoglobulin-binding proteins and recombinant dna molecules coding therefor
JP2584697B2 (ja) * 1991-08-23 1997-02-26 オリエンタル酵母工業株式会社 ＩｇＧ精製用組換え型プロテインＡ
WO1995006125A1 (en) * 1993-08-23 1995-03-02 Applied Immune Sciences, Inc. CHIMERIC RECEPTOR CONTAINING ONE IgG BINDING DOMAIN OF BOTH PROTEIN A AND PROTEIN G
US6949244B1 (en) 1995-12-20 2005-09-27 The Board Of Trustees Of The University Of Kentucky Murine monoclonal anti-idiotype antibody 11D10 and methods of use thereof
SE9901379D0 (sv) 1999-04-19 1999-04-19 Pharmacia & Upjohn Ab Receptor structures
US20040077017A1 (en) * 2001-01-12 2004-04-22 Amelie Karlstrom Detection methods
US7709209B2 (en) * 2002-03-25 2010-05-04 Ge Healthcare Bio-Sciences Ab Protein ligands
CA2515213A1 (en) * 2003-02-11 2004-08-26 University Of Washington Stimuli-responsive polymer conjugates and related methods
IL157086A0 (en) 2003-07-24 2004-02-08 Guy Patchornik Multivalent ligand complexes
WO2006065208A1 (en) 2004-12-14 2006-06-22 Ge Healthcare Bio-Sciences Ab Purification of immunoglobulins
US8728828B2 (en) * 2004-12-22 2014-05-20 Ge Healthcare Bio-Sciences Ab Purification of immunoglobulins
ZA200710330B (en) * 2005-06-17 2009-12-30 Wyeth Corp Methods of purifying FC region containing proteins
CN101287503A (zh) * 2005-08-03 2008-10-15 Rq生物科技有限公司 用于诊断IgA和IgM介导的肾脏疾病的方法和组合物
JP4481260B2 (ja) * 2006-03-16 2010-06-16 株式会社カネカ 抗体結合性ペプチド
WO2008039141A1 (en) * 2006-09-29 2008-04-03 Ge Healthcare Bio-Sciences Ab Chromatography ligand comprising domain c from staphyloccocus aureus protein a for antibody isolation
DK2102239T3 (da) * 2006-11-30 2012-05-29 Res Dev Foundation Forbedrede immunoglobulin-biblioteker
EP2099932A4 (en) 2006-12-06 2009-11-18 Repligen Corp NUCLEIC ACIDS ENCODING THE RECOMBINANT PROTEIN A
DK2220107T3 (en) 2007-11-12 2017-02-13 Chreto Aps Double affinity polypeptide for purification
US8592555B2 (en) * 2008-08-11 2013-11-26 Emd Millipore Corporation Immunoglobulin-binding proteins with improved specificity
EP2389386A4 (en) * 2009-01-12 2013-11-06 Ge Healthcare Bio Sciences Ab affinity chromatography

Also Published As

Publication number Publication date
CN102791728B (zh) 2015-04-01
KR20130004476A (ko) 2013-01-10
WO2011107518A1 (de) 2011-09-09
US20140128578A1 (en) 2014-05-08
JP2013521258A (ja) 2013-06-10
US20210107937A1 (en) 2021-04-15
US20120071637A1 (en) 2012-03-22
AU2011222991B2 (en) 2015-07-16
CA2791918A1 (en) 2011-09-09
KR101855714B1 (ko) 2018-05-10
JP5917417B2 (ja) 2016-05-11
CN102791728A (zh) 2012-11-21
EP2542567A2 (de) 2013-01-09
SG183920A1 (en) 2012-10-30
EP2542567B1 (de) 2020-02-12
TW201144325A (en) 2011-12-16
AU2011222991A1 (en) 2012-09-20
US10894806B2 (en) 2021-01-19
CA2791918C (en) 2019-11-19

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