AR240920A2 - "un procedimiento para la preparacion de nuevos derivados de quinolina". - Google Patents
"un procedimiento para la preparacion de nuevos derivados de quinolina".Info
- Publication number
- AR240920A2 AR240920A2 AR30028485A AR30028485A AR240920A2 AR 240920 A2 AR240920 A2 AR 240920A2 AR 30028485 A AR30028485 A AR 30028485A AR 30028485 A AR30028485 A AR 30028485A AR 240920 A2 AR240920 A2 AR 240920A2
- Authority
- AR
- Argentina
- Prior art keywords
- preparation
- quinoline derivatives
- same
- compositions containing
- therapeutic compositions
- Prior art date
Links
- 229940027991 antiseptic and disinfectant quinoline derivative Drugs 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title 1
- 125000002943 quinolinyl group Chemical class N1=C(C=CC2=CC=CC=C12)* 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
- ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical compound CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 2
- BWHMMNNQKKPAPP-UHFFFAOYSA-L potassium carbonate Chemical compound [K+].[K+].[O-]C([O-])=O BWHMMNNQKKPAPP-UHFFFAOYSA-L 0.000 abstract 2
- SMWDFEZZVXVKRB-UHFFFAOYSA-N Quinoline Chemical class N1=CC=CC2=CC=CC=C21 SMWDFEZZVXVKRB-UHFFFAOYSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000003784 fluoroethyl group Chemical group [H]C([H])(F)C([H])([H])* 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical group 0.000 abstract 1
- 229910000027 potassium carbonate Inorganic materials 0.000 abstract 1
- 235000015320 potassium carbonate Nutrition 0.000 abstract 1
- 238000010992 reflux Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
- C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Quinoline Compounds (AREA)
Abstract
UN PROCEDIMIENTO PARA LA PREPARACION DE NUEVOS DERIVADOS DE QUINOLINA DE FORMULA I, DONDE R REPRESENTA C2H5, C2H4F,CH2-O-CH2OH,CH2; EL PROCESO SE BASA EN HACER REACCIONAR, DURANTE 12-24 HORAS, A 70-95OC, EN DIMETILFORMAMIDA, LA 1,4-DIHIDRO-3-ETOXICARBONIL-6,8-DIFLUORO-4OXO-QUINOLINA CON 2 A 5 MOLES DE UN COMPUESTO DE FORMULA RX, DONDE R TIENE LOS SIGNIFICADOS YA INDICADOS Y X ES HALOGENO, EN PRESENCIA DE K2CO3; E HIDROLIZAR A CONTINUACION EL 3-ETER OBTENIDO CON HC1 BAJO CONDICIONES DE REFLUJO.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB848412094A GB8412094D0 (en) | 1984-05-11 | 1984-05-11 | Quinoline derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AR240920A1 AR240920A1 (es) | 1991-03-27 |
| AR240920A2 true AR240920A2 (es) | 1991-03-27 |
Family
ID=10560821
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AR300284A AR240920A1 (es) | 1984-05-11 | 1985-05-03 | "un procedimiento para la preparacion de nuevos derivados de quinolina". |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US4782068A (es) |
| JP (1) | JPS60246370A (es) |
| AR (1) | AR240920A1 (es) |
| AT (1) | AT391314B (es) |
| BE (1) | BE902337A (es) |
| CA (1) | CA1291136C (es) |
| CH (1) | CH664363A5 (es) |
| DE (1) | DE3516938A1 (es) |
| DK (1) | DK163826C (es) |
| DZ (1) | DZ779A1 (es) |
| ES (1) | ES543014A0 (es) |
| FI (1) | FI82688C (es) |
| FR (2) | FR2563995B1 (es) |
| GB (2) | GB8412094D0 (es) |
| HK (1) | HK57288A (es) |
| IE (1) | IE58304B1 (es) |
| IT (1) | IT1200472B (es) |
| LU (1) | LU85876A1 (es) |
| MA (1) | MA20427A1 (es) |
| NL (1) | NL8501309A (es) |
| NO (1) | NO167025C (es) |
| OA (1) | OA08030A (es) |
| PT (1) | PT80433B (es) |
| SE (1) | SE463152B (es) |
| SG (1) | SG23388G (es) |
| ZA (1) | ZA853268B (es) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2049652B1 (es) * | 1992-09-16 | 1994-10-01 | Genesis Para La Investigacion | Procedimiento para la preparacion de un acido quinolin carboxilico. |
| RU2206564C1 (ru) * | 2002-03-07 | 2003-06-20 | Общество с ограниченной ответственностью "Поливит" | Способ получения этилового эфира 6-фтор-7-хлор-1,4-дигидро-4-оксо-3-хинолинкарбоновой кислоты |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4146625A (en) * | 1976-07-16 | 1979-03-27 | E. I. Du Pont De Nemours And Company | Quinolonecarboxylic acids for control of bacterial diseases in plants |
| US4264604A (en) * | 1977-07-01 | 1981-04-28 | Ciba-Geigy Corporation | Quinolonecarboxylic acid derivatives as bactericides |
| JPS5630964A (en) * | 1979-08-22 | 1981-03-28 | Kyorin Pharmaceut Co Ltd | Novel substituted quinolinecarboxylic acid and its preparation |
| JPS5653656A (en) * | 1979-10-05 | 1981-05-13 | Tanabe Seiyaku Co Ltd | Quinoline derivative and its preparation |
| DE3142854A1 (de) * | 1981-10-29 | 1983-05-11 | Bayer Ag, 5090 Leverkusen | 1-cyclopropyl-6-fluor-1,4-dihydro-4-oxo-7-piperazino-chinolin-3-carbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel |
-
1984
- 1984-05-11 GB GB848412094A patent/GB8412094D0/en active Pending
-
1985
- 1985-04-30 GB GB08510975A patent/GB2163742B/en not_active Expired
- 1985-05-01 ZA ZA853268A patent/ZA853268B/xx unknown
- 1985-05-02 BE BE0/214951A patent/BE902337A/fr not_active IP Right Cessation
- 1985-05-02 LU LU85876A patent/LU85876A1/fr unknown
- 1985-05-03 AR AR300284A patent/AR240920A1/es active
- 1985-05-06 CH CH1912/85A patent/CH664363A5/fr not_active IP Right Cessation
- 1985-05-06 FI FI851774A patent/FI82688C/fi not_active IP Right Cessation
- 1985-05-06 MA MA20651A patent/MA20427A1/fr unknown
- 1985-05-08 NL NL8501309A patent/NL8501309A/nl not_active Application Discontinuation
- 1985-05-08 DZ DZ850095A patent/DZ779A1/fr active
- 1985-05-09 CA CA000481189A patent/CA1291136C/en not_active Expired - Lifetime
- 1985-05-09 SE SE8502310A patent/SE463152B/sv not_active IP Right Cessation
- 1985-05-10 ES ES543014A patent/ES543014A0/es active Granted
- 1985-05-10 FR FR8507074A patent/FR2563995B1/fr not_active Expired
- 1985-05-10 PT PT80433A patent/PT80433B/pt not_active IP Right Cessation
- 1985-05-10 NO NO851868A patent/NO167025C/no unknown
- 1985-05-10 OA OA58592A patent/OA08030A/xx unknown
- 1985-05-10 DE DE19853516938 patent/DE3516938A1/de active Granted
- 1985-05-10 JP JP60098200A patent/JPS60246370A/ja active Granted
- 1985-05-10 IT IT20655/85A patent/IT1200472B/it active
- 1985-05-10 DK DK207985A patent/DK163826C/da not_active IP Right Cessation
- 1985-05-10 IE IE116185A patent/IE58304B1/en not_active IP Right Cessation
- 1985-05-10 FR FR8507075A patent/FR2564094B1/fr not_active Expired
- 1985-05-13 AT AT0143885A patent/AT391314B/de not_active IP Right Cessation
-
1987
- 1987-03-04 US US07/022,620 patent/US4782068A/en not_active Expired - Fee Related
-
1988
- 1988-04-08 SG SG233/88A patent/SG23388G/en unknown
- 1988-07-28 HK HK572/88A patent/HK57288A/xx not_active IP Right Cessation
Also Published As
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