ATE39920T1 - Cyclopentylether, verfahren zu ihrer herstellung und ihre pharmazeutische anwendung. - Google Patents

Cyclopentylether, verfahren zu ihrer herstellung und ihre pharmazeutische anwendung.

Info

Publication number
ATE39920T1
ATE39920T1 AT85302830T AT85302830T ATE39920T1 AT E39920 T1 ATE39920 T1 AT E39920T1 AT 85302830 T AT85302830 T AT 85302830T AT 85302830 T AT85302830 T AT 85302830T AT E39920 T1 ATE39920 T1 AT E39920T1
Authority
AT
Austria
Prior art keywords
sub
production
pharmaceutical application
cyclopentyl ether
sup
Prior art date
Application number
AT85302830T
Other languages
English (en)
Inventor
Eric William Collington
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Application granted granted Critical
Publication of ATE39920T1 publication Critical patent/ATE39920T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/753—Unsaturated compounds containing a keto groups being part of a ring containing ether groups, groups, groups, or groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/56—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
    • C07C45/57—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom
    • C07C45/58—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom in three-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
    • C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00—Compounds having —CHO groups
    • C07C47/20—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms
    • C07C47/277—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/613—Unsaturated compounds containing a keto groups being part of a ring polycyclic
    • C07C49/617—Unsaturated compounds containing a keto groups being part of a ring polycyclic a keto group being part of a condensed ring system
    • C07C49/623—Unsaturated compounds containing a keto groups being part of a ring polycyclic a keto group being part of a condensed ring system having two rings
    • C07C49/627—Unsaturated compounds containing a keto groups being part of a ring polycyclic a keto group being part of a condensed ring system having two rings the condensed ring system containing seven carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT85302830T 1984-04-24 1985-04-23 Cyclopentylether, verfahren zu ihrer herstellung und ihre pharmazeutische anwendung. ATE39920T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB848410396A GB8410396D0 (en) 1984-04-24 1984-04-24 Carbocyclic compounds
EP85302830A EP0160495B1 (de) 1984-04-24 1985-04-23 Cyclopentylether, Verfahren zu ihrer Herstellung und ihre pharmazeutische Anwendung

Publications (1)

Publication Number Publication Date
ATE39920T1 true ATE39920T1 (de) 1989-01-15

Family

ID=10559964

Family Applications (1)

Application Number Title Priority Date Filing Date
AT85302830T ATE39920T1 (de) 1984-04-24 1985-04-23 Cyclopentylether, verfahren zu ihrer herstellung und ihre pharmazeutische anwendung.

Country Status (10)

Country Link
US (1) US4837363A (de)
EP (1) EP0160495B1 (de)
JP (1) JPS60252459A (de)
AT (1) ATE39920T1 (de)
AU (1) AU588526B2 (de)
CA (1) CA1248527A (de)
DE (1) DE3567453D1 (de)
DK (1) DK180985A (de)
GB (1) GB8410396D0 (de)
ZA (1) ZA853016B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4824993A (en) * 1984-04-23 1989-04-25 Glaxo Group Limited Cyclopentyl ethers and their preparation and pharmaceutical formulation
GB8510277D0 (en) * 1985-04-23 1985-05-30 Glaxo Group Ltd Carbocyclic compounds
GB8625321D0 (en) * 1986-10-22 1986-11-26 Glaxo Group Ltd Chemical compounds
GB8625326D0 (en) * 1986-10-22 1986-11-26 Glaxo Group Ltd Medicaments
GB8625322D0 (en) * 1986-10-22 1986-11-26 Glaxo Group Ltd Chemical compounds
JP2696933B2 (ja) * 1987-06-16 1998-01-14 日産化学工業株式会社 置換環状ケトン及び置換環状エノン並びにそれらの製造法
US5231208A (en) * 1987-06-16 1993-07-27 Nissan Chemical Industries, Ltd. Substituted cyclic ketones, substituted cyclic enones, and process for producing the same
US5227505A (en) * 1987-06-16 1993-07-13 Nissan Chemical Industries, Ltd. Substituted cyclic ketones, substituted cyclic enones, and process for producing the same
US5254708A (en) * 1987-06-16 1993-10-19 Nissan Chemical Industries, Ltd. Substituted cyclic ketones, substituted cyclic enones, and process for producing the same
WO1999032441A1 (en) * 1997-12-22 1999-07-01 Alcon Laboratories, Inc. 13-oxa prostaglandins for the treatment of glaucoma and ocular hypertension
US7868045B2 (en) 2006-09-06 2011-01-11 Sucampo Ag Method for promoting gastrointestinal bicarbonate secretion

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4271314A (en) * 1979-11-28 1981-06-02 G. D. Searle & Co. 4,5-Unsaturated prostanoic acid derivatives
GB2082176B (en) * 1980-08-12 1984-07-11 Sanofi Sa Heteroprostaglandin derivatives and processes for preparing them
HU184950B (en) * 1981-04-14 1984-11-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing new 13-oxa-prostacyclin derivatives
JPS595154A (ja) * 1982-06-30 1984-01-12 Ono Pharmaceut Co Ltd プロスタグランジンｄ類似化合物
US4499296A (en) * 1983-11-14 1985-02-12 G. D. Searle & Co. Omega cycloalkyl prostaglandins

Also Published As

Publication number Publication date
DK180985D0 (da) 1985-04-23
CA1248527A (en) 1989-01-10
GB8410396D0 (en) 1984-05-31
DE3567453D1 (en) 1989-02-16
ZA853016B (en) 1985-12-24
US4837363A (en) 1989-06-06
AU588526B2 (en) 1989-09-21
AU4163185A (en) 1985-10-31
EP0160495A2 (de) 1985-11-06
EP0160495A3 (en) 1986-08-27
JPS60252459A (ja) 1985-12-13
DK180985A (da) 1985-10-25
EP0160495B1 (de) 1989-01-11

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee