AT257038B - Verfahren zur Herstellung von Aminoacylanalogen von Cephalosporin C - Google Patents
Verfahren zur Herstellung von Aminoacylanalogen von Cephalosporin CInfo
- Publication number
- AT257038B AT257038B AT579463A AT579463A AT257038B AT 257038 B AT257038 B AT 257038B AT 579463 A AT579463 A AT 579463A AT 579463 A AT579463 A AT 579463A AT 257038 B AT257038 B AT 257038B
- Authority
- AT
- Austria
- Prior art keywords
- aminoacyl
- cephalosporin
- analogs
- preparation
- aminoacyl analogs
- Prior art date
Links
- HOKIDJSKDBPKTQ-GLXFQSAKSA-N cephalosporin C Chemical compound S1CC(COC(=O)C)=C(C(O)=O)N2C(=O)[C@@H](NC(=O)CCC[C@@H](N)C(O)=O)[C@@H]12 HOKIDJSKDBPKTQ-GLXFQSAKSA-N 0.000 title 2
- 125000000266 alpha-aminoacyl group Chemical group 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
- A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
- C07D501/32—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by an araliphatic carboxylic acid, which is substituted on the aliphatic radical by hetero atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB2803962 | 1962-07-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AT257038B true AT257038B (de) | 1967-09-25 |
Family
ID=10269280
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT579463A AT257038B (de) | 1962-07-20 | 1963-07-19 | Verfahren zur Herstellung von Aminoacylanalogen von Cephalosporin C |
Country Status (8)
| Country | Link |
|---|---|
| AT (1) | AT257038B (de) |
| CH (1) | CH441323A (de) |
| DE (1) | DE1445822C3 (de) |
| DK (1) | DK118083B (de) |
| ES (1) | ES289733A1 (de) |
| FR (1) | FR3065M (de) |
| NL (1) | NL142164B (de) |
| SE (1) | SE334891B (de) |
-
1963
- 1963-07-05 DK DK319163AA patent/DK118083B/da unknown
- 1963-07-06 ES ES0289733A patent/ES289733A1/es not_active Expired
- 1963-07-10 NL NL63295124A patent/NL142164B/xx unknown
- 1963-07-11 FR FR941091A patent/FR3065M/fr active Active
- 1963-07-15 DE DE1445822A patent/DE1445822C3/de not_active Expired
- 1963-07-18 CH CH897463A patent/CH441323A/de unknown
- 1963-07-19 SE SE08036/63A patent/SE334891B/xx unknown
- 1963-07-19 AT AT579463A patent/AT257038B/de active
Also Published As
| Publication number | Publication date |
|---|---|
| ES289733A1 (es) | 1963-12-01 |
| FR3065M (fr) | 1965-01-18 |
| NL142164B (nl) | 1974-05-15 |
| DE1445822C3 (de) | 1973-12-13 |
| DE1445822B2 (de) | 1973-05-24 |
| DK118083B (da) | 1970-07-06 |
| CH441323A (de) | 1967-08-15 |
| SE334891B (de) | 1971-05-10 |
| DE1445822A1 (de) | 1969-04-17 |
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