DK118083B - Analogifremgangsmåde til fremstilling af 7-(aminoacylamido)-cephalosporansyrederivater. - Google Patents

Analogifremgangsmåde til fremstilling af 7-(aminoacylamido)-cephalosporansyrederivater.

Info

Publication number
DK118083B
DK118083B DK319163AA DK319163A DK118083B DK 118083 B DK118083 B DK 118083B DK 319163A A DK319163A A DK 319163AA DK 319163 A DK319163 A DK 319163A DK 118083 B DK118083 B DK 118083B
Authority
DK
Denmark
Prior art keywords
aminoacylamido
preparation
acid derivatives
cephalosporanic acid
analogous process
Prior art date
Application number
DK319163AA
Other languages
English (en)
Inventor
W Wall
M Fatherley
B Boothroyd
Original Assignee
Glaxo Lab Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Lab Ltd filed Critical Glaxo Lab Ltd
Publication of DK118083B publication Critical patent/DK118083B/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • C07D501/32—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by an araliphatic carboxylic acid, which is substituted on the aliphatic radical by hetero atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
DK319163AA 1962-07-20 1963-07-05 Analogifremgangsmåde til fremstilling af 7-(aminoacylamido)-cephalosporansyrederivater. DK118083B (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2803962 1962-07-20

Publications (1)

Publication Number Publication Date
DK118083B true DK118083B (da) 1970-07-06

Family

ID=10269280

Family Applications (1)

Application Number Title Priority Date Filing Date
DK319163AA DK118083B (da) 1962-07-20 1963-07-05 Analogifremgangsmåde til fremstilling af 7-(aminoacylamido)-cephalosporansyrederivater.

Country Status (8)

Country Link
AT (1) AT257038B (da)
CH (1) CH441323A (da)
DE (1) DE1445822C3 (da)
DK (1) DK118083B (da)
ES (1) ES289733A1 (da)
FR (1) FR3065M (da)
NL (1) NL142164B (da)
SE (1) SE334891B (da)

Also Published As

Publication number Publication date
ES289733A1 (es) 1963-12-01
FR3065M (fr) 1965-01-18
NL142164B (nl) 1974-05-15
DE1445822C3 (de) 1973-12-13
DE1445822B2 (de) 1973-05-24
CH441323A (de) 1967-08-15
SE334891B (da) 1971-05-10
DE1445822A1 (de) 1969-04-17
AT257038B (de) 1967-09-25

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