AT98254B - Process for the production of durable, oily emulsions of bismuth salts. - Google Patents
Process for the production of durable, oily emulsions of bismuth salts.Info
- Publication number
- AT98254B AT98254B AT98254DA AT98254B AT 98254 B AT98254 B AT 98254B AT 98254D A AT98254D A AT 98254DA AT 98254 B AT98254 B AT 98254B
- Authority
- AT
- Austria
- Prior art keywords
- durable
- production
- bismuth salts
- oily emulsions
- emulsions
- Prior art date
Links
- 239000000839 emulsion Substances 0.000 title description 6
- 150000001621 bismuth Chemical class 0.000 title description 4
- 238000004519 manufacturing process Methods 0.000 title description 2
- 238000000034 method Methods 0.000 title description 2
- 150000001622 bismuth compounds Chemical class 0.000 description 3
- 239000003960 organic solvent Substances 0.000 description 2
- 150000001875 compounds Chemical class 0.000 description 1
- 235000014113 dietary fatty acids Nutrition 0.000 description 1
- 239000002552 dosage form Substances 0.000 description 1
- 229930195729 fatty acid Natural products 0.000 description 1
- 239000000194 fatty acid Substances 0.000 description 1
- 150000004665 fatty acids Chemical class 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 238000010255 intramuscular injection Methods 0.000 description 1
- 239000007927 intramuscular injection Substances 0.000 description 1
- 238000001990 intravenous administration Methods 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 238000010254 subcutaneous injection Methods 0.000 description 1
- 239000007929 subcutaneous injection Substances 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
Landscapes
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Description
<Desc/Clms Page number 1>
Verfahren zur Herstellung von haltbaren, öligen Emulsionen von Wismutsalzen.
In neuerer Zeit haben die Wismutverbindungen in der Therapie eine erhöhte Beachtung erlangt.
Für ihre zweckmässige Anwendung sind Darreichlmgsformen erforderlich, welche diese Verbindungen gelöst oder in feinster Verteilung enthalten und sich für die intravenöse bzw. parenterale Injektion eignen. Für die subcutan und intramuskuläre Injektion erwiesen sich Emulsionen von unlöslichen Wismutverbindungen als besonders vorteilhaft.
Es wurde nun gefunden, dass man haltbare, ölige Emulsionen von Wismutsalzen durch Auflosung der Wismutsalze von Fettsäuren in geeigneten organischen Lösungsmitteln, Vermischen dieser Lösungen mit einem Öl und Abdestillieren des organischen Lösungsmittels erhält. Die auf diese Weise gewonnenen Emulsionen zeigen selbst nach längerem Stehen keine Abscheidungen. Sie enthalten die Wismutverbin- dungen stets in feinster Verteilung, welche bedingt, dass die Emulsionen leicht injizierbar sind und gut resorbiert werden.
EMI1.1
**WARNUNG** Ende DESC Feld kannt Anfang CLMS uberlappen**.
<Desc / Clms Page number 1>
Process for the production of durable, oily emulsions of bismuth salts.
In recent times the bismuth compounds have received increased attention in therapy.
For their appropriate use, dosage forms are required which contain these compounds in dissolved form or in extremely fine distribution and are suitable for intravenous or parenteral injection. Emulsions of insoluble bismuth compounds have proven particularly advantageous for subcutaneous and intramuscular injection.
It has now been found that durable, oily emulsions of bismuth salts are obtained by dissolving the bismuth salts of fatty acids in suitable organic solvents, mixing these solutions with an oil and distilling off the organic solvent. The emulsions obtained in this way show no deposits even after prolonged standing. They always contain the bismuth compounds in the finest distribution, which means that the emulsions are easy to inject and are well absorbed.
EMI1.1
** WARNING ** End of DESC field may overlap beginning of CLMS **.
Claims (1)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH98254X | 1922-11-01 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AT98254B true AT98254B (en) | 1924-10-25 |
Family
ID=4356038
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98254D AT98254B (en) | 1922-11-01 | 1923-09-19 | Process for the production of durable, oily emulsions of bismuth salts. |
Country Status (1)
| Country | Link |
|---|---|
| AT (1) | AT98254B (en) |
-
1923
- 1923-09-19 AT AT98254D patent/AT98254B/en active
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