ATA10882A - Verfahren zur herstellung von neuen 6betahydroxyalkylpenicillansaeurederivaten - Google Patents

Verfahren zur herstellung von neuen 6betahydroxyalkylpenicillansaeurederivaten

Info

Publication number: ATA10882A
Authority: AT; Austria
Prior art keywords: derivatives; producing new; producing; new
Prior art date: 1979-10-22

Application number

AT0010882A

Other languages

English (en)

Other versions

AT374479B (de

Inventor

Michael Stephen Kellogg

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1979-10-22

Filing date

1982-01-13

Publication date

1983-09-15

1982-01-13 Application filed by Pfizer filed Critical Pfizer

1982-01-13 Priority to AT0010882A priority Critical patent/AT374479B/de

1983-09-15 Publication of ATA10882A publication Critical patent/ATA10882A/de

1984-04-25 Application granted granted Critical

1984-04-25 Publication of AT374479B publication Critical patent/AT374479B/de

Links

238000004519 manufacturing process Methods 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D499/04—Preparation
- C07D499/08—Modification of a carboxyl radical directly attached in position 2, e.g. esterification
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D499/21—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a nitrogen atom directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D499/44—Compounds with an amino radical acylated by carboxylic acids, attached in position 6
- C07D499/74—Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with carbocyclic rings directly attached to the carboxamido radical

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Oncology (AREA)
Pharmacology & Pharmacy (AREA)
Communicable Diseases (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Catalysts (AREA)

AT0010882A 1979-10-22 1982-01-13 Verfahren zur herstellung von neuen 6betahydroxyalkylpenicillansaeurederivaten AT374479B (de)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
AT0010882A AT374479B (de)	1979-10-22	1982-01-13	Verfahren zur herstellung von neuen 6betahydroxyalkylpenicillansaeurederivaten

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US06/086,864 US4287181A (en)	1979-10-22	1979-10-22	Derivatives of 6β-hydroxyalkylpenicillanic acids as β-lactamase inhibitors
AT0518580A AT369372B (de)	1979-10-22	1980-10-20	Verfahren zur herstellung von neuen 6beta-hydroxyalkylpenicillansaeurederivaten
AT0010882A AT374479B (de)	1979-10-22	1982-01-13	Verfahren zur herstellung von neuen 6betahydroxyalkylpenicillansaeurederivaten

Publications (2)

Publication Number	Publication Date
ATA10882A true ATA10882A (de)	1983-09-15
AT374479B AT374479B (de)	1984-04-25

Family

ID=22201393

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
AT0518580A AT369372B (de)	1979-10-22	1980-10-20	Verfahren zur herstellung von neuen 6beta-hydroxyalkylpenicillansaeurederivaten
AT0010882A AT374479B (de)	1979-10-22	1982-01-13	Verfahren zur herstellung von neuen 6betahydroxyalkylpenicillansaeurederivaten

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
AT0518580A AT369372B (de)	1979-10-22	1980-10-20	Verfahren zur herstellung von neuen 6beta-hydroxyalkylpenicillansaeurederivaten

Country Status (38)

Country	Link
US (1)	US4287181A (de)
JP (2)	JPS5665892A (de)
KR (1)	KR840000797B1 (de)
AR (1)	AR227164A1 (de)
AT (2)	AT369372B (de)
AU (1)	AU519578B2 (de)
BE (1)	BE885812A (de)
BG (2)	BG38639A3 (de)
CA (2)	CA1144159A (de)
CH (2)	CH646175A5 (de)
CS (2)	CS219291B2 (de)
DD (1)	DD154542A5 (de)
DE (1)	DE3039504C2 (de)
DK (1)	DK389480A (de)
ES (1)	ES496166A0 (de)
FI (1)	FI71156C (de)
FR (1)	FR2467852A1 (de)
GB (3)	GB2061930B (de)
GR (1)	GR70714B (de)
GT (1)	GT198065892A (de)
HU (1)	HU183236B (de)
IE (3)	IE51027B1 (de)
IL (1)	IL61307A (de)
IN (1)	IN154918B (de)
IT (1)	IT1149259B (de)
LU (1)	LU82880A1 (de)
MX (1)	MX6094E (de)
NL (1)	NL183358C (de)
NO (1)	NO159019C (de)
NZ (1)	NZ195307A (de)
PH (5)	PH16219A (de)
PL (2)	PL129534B1 (de)
PT (1)	PT71946B (de)
RO (2)	RO81225B (de)
SE (1)	SE451455B (de)
SU (2)	SU1122227A3 (de)
YU (2)	YU41743B (de)
ZA (1)	ZA806452B (de)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IE49770B1 (en) *	1979-05-21	1985-12-11	Leo Pharm Prod Ltd	6beta-halopenicillanic acid derivatives
GB2076812A (en) *	1980-05-22	1981-12-09	Ciba Geigy Ag	Penam-dioxide compounds, processes for their manufacture, and their use
US4444687A (en) *	1981-06-08	1984-04-24	Bristol-Myers Company	2β-Chloromethyl-2α-methylpenam-3α-carboxylic acid sulfone methylene diol mixed esters
ZA826687B (en) *	1981-09-14	1983-07-27	Pfizer	Beta-lactamase inhibiting 2-beta-substituted-2-alpha-methyl 5(r)penam-3-alpha-carboxylic acid 1,1-dioxides and intermediates therefor
US4351840A (en) *	1981-09-18	1982-09-28	Pfizer Inc.	Antibacterial esters of resorcinol with ampicillin and penicillanic acid 1,1-dioxide derivatives
JPS58109490A (ja) *	1981-12-21	1983-06-29	Sankyo Co Ltd	ペニシリン誘導体
US4427678A (en)	1982-01-11	1984-01-24	Pfizer Inc.	6-Aminomethylpenicillanic acid 1,1-dioxide derivatives as beta-lactamase inhibitors
RO87705A (ro) *	1982-01-11	1985-10-31	Pfizer Inc,Us	Procedeu pentru prepararea unor derivati ai acidului 6-aminoalchilpenicilanic 1,1-dioxid
US4452796A (en) *	1982-06-14	1984-06-05	Pfizer Inc.	6-Aminoalkylpenicillanic acid 1,1-dioxides as beta-lactamase inhibitors
US4377590A (en) *	1982-05-10	1983-03-22	Pfizer Inc.	Derivatives of ampicillin and amoxicillin with beta-lactamase inhibitors
US4502990A (en) *	1983-06-06	1985-03-05	Pfizer Inc.	Process for 6-(aminomethyl)penicillanic acid 1,1-dioxide and derivatives thereof
US4588527A (en) *	1983-06-06	1986-05-13	Pfizer Inc.	Process for preparing penicillanic acid 1,1-dioxide derivatives
US4536393A (en) *	1983-06-06	1985-08-20	Pfizer Inc.	6-(Aminomethyl)penicillanic acid 1,1-dioxide esters and intermediates therefor
US4499017A (en) *	1983-06-06	1985-02-12	Pfizer Inc.	Beta-lactamase inhibiting 6-(alkoxyamino-methyl) penicillanic acid 1,1-dioxide and derivatives
US4502988A (en) *	1983-08-08	1985-03-05	Eli Lilly And Company	Oxidation process
US4826833A (en) *	1984-01-30	1989-05-02	Pfizer Inc.	6-(Substituted)methylene-penicillanic and 6-(substituted)hydroxymethylpenicillanic acids and derivatives thereof
EP0150984B1 (de) *	1984-01-30	1991-09-11	Pfizer Inc.	6-(substituierte) Methylen-Penicillansäure und 6-(substituierte) Hydroxymethyl-Penicillansäure und deren Derivate
DD247677A5 (de) *	1984-01-30	1987-07-15	��@��Kk��	Verfahren zur herstellung von 6-(subst.)-methylenpenicillan- und 6-(subst.)-hydroxymehtylpenicillansaeure und deren derivaten
US5015473A (en) *	1984-01-30	1991-05-14	Pfizer Inc.	6-(substituted)methylenepenicillanic and 6-(substituted)hydroxymethylpenicillanic acids and derivatives thereof
US4503040A (en) *	1984-02-27	1985-03-05	Pfizer Inc.	6-(Aminoacyloxymethyl)penicillanic acid 1,1-dioxides as beta-lactamase inhibitors
US4847247A (en) *	1984-07-30	1989-07-11	Merck & Co., Inc.	Penicillin derivatives as anti-inflammatory and antidegenerative agents
US4590073A (en) *	1984-10-22	1986-05-20	Pfizer Inc.	6-substituted penicillanic acid 1,1-dioxide compounds
US4591459A (en) *	1984-12-03	1986-05-27	Pfizer Inc.	Intermediates for 6-(aminoacyloxymethyl) penicillanic acid 1,1-dioxides
US4675186A (en)	1985-04-18	1987-06-23	Pfizer Inc.	6-(1-acyl-1-hydroxymethyl)penicillanic acid derivatives
US4762921A (en) *	1985-04-18	1988-08-09	Pfizer Inc.	6-(1-acyl-1-hydroxymethyl)penicillanic acid derivatives
US4613462A (en) *	1985-07-02	1986-09-23	Pfizer, Inc.	6-substituted penicillanic acid 1,1-dioxide compounds
US4782050A (en) *	1987-01-27	1988-11-01	Pfizer Inc.	6-beta(substituted)-(S)-hydroxymethylpenicillanic acids and derivatives thereof
EP0276942B1 (de) *	1987-01-27	1992-04-01	Pfizer Inc.	6-Beta(substituierte)-(S)-hydroxymethylpenicillansäure und deren Derivate
US6395726B1 (en)	1999-01-26	2002-05-28	American Cyanamid Company	3,6-disubstituted penam sulfone derivatives
PA8579701A1 (es) *	2002-08-23	2005-05-24	Pfizer Prod Inc	Profarmaco inhibidor de beta-lactamasa
JP2006526612A (ja) *	2003-06-05	2006-11-24	ファイザー・プロダクツ・インク	ベータ−ラクタマーゼ阻害剤・プロドラッグ
JP5300713B2 (ja) *	2007-03-09	2013-09-25	大塚化学株式会社	６−ヒドロキシエチルペナム化合物の製造方法
CN109422765B (zh) *	2017-09-05	2020-08-28	香港理工大学深圳研究院	C类β-内酰胺酶抑制剂及其制备方法和应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5749555B2 (de) *	1973-04-04	1982-10-22
US4207323A (en) *	1975-11-21	1980-06-10	Merck & Co., Inc.	6-Substituted methyl penicillins, derivatives and analogues thereof
US4053468A (en) *	1976-02-25	1977-10-11	Smithkline Corporation	Process for preparing 7-oxo cephalosporins and 6-oxo penicillins
US4093625A (en) *	1976-08-09	1978-06-06	Massachusetts Institute Of Technology	6-Sulfur analogs of penicillins and cephalosporins
US4123539A (en) *	1977-12-29	1978-10-31	Merck & Co., Inc.	6-Ethylpenicillanic acid
US4272439A (en) *	1978-06-02	1981-06-09	Schering Corporation	6-(Substituted-hydroxymethylene penams)
JPS5598186A (en) *	1979-01-10	1980-07-25	Beecham Group Ltd	Manufacture of penicillin derivative
GB2076812A (en) *	1980-05-22	1981-12-09	Ciba Geigy Ag	Penam-dioxide compounds, processes for their manufacture, and their use

1979
- 1979-10-22 US US06/086,864 patent/US4287181A/en not_active Expired - Lifetime
1980
- 1980-09-12 DK DK389480A patent/DK389480A/da not_active Application Discontinuation
- 1980-10-08 IN IN736/DEL/80A patent/IN154918B/en unknown
- 1980-10-11 GR GR63135A patent/GR70714B/el unknown
- 1980-10-16 GB GB33342A patent/GB2061930B/en not_active Expired
- 1980-10-17 GT GT198065892A patent/GT198065892A/es unknown
- 1980-10-20 AT AT0518580A patent/AT369372B/de not_active IP Right Cessation
- 1980-10-20 IL IL61307A patent/IL61307A/xx unknown
- 1980-10-20 YU YU2676/80A patent/YU41743B/xx unknown
- 1980-10-20 CS CS807098A patent/CS219291B2/cs unknown
- 1980-10-20 JP JP14677480A patent/JPS5665892A/ja active Granted
- 1980-10-20 DE DE3039504A patent/DE3039504C2/de not_active Expired
- 1980-10-20 SE SE8007354A patent/SE451455B/sv not_active IP Right Cessation
- 1980-10-20 CA CA000362762A patent/CA1144159A/en not_active Expired
- 1980-10-20 PH PH24748A patent/PH16219A/en unknown
- 1980-10-20 AR AR282932A patent/AR227164A1/es active
- 1980-10-20 NZ NZ195307A patent/NZ195307A/en unknown
- 1980-10-21 PL PL1980227420A patent/PL129534B1/pl unknown
- 1980-10-21 PL PL1980235907A patent/PL129638B1/pl unknown
- 1980-10-21 IE IE293/85A patent/IE51027B1/en unknown
- 1980-10-21 IE IE2229/85A patent/IE51028B1/en unknown
- 1980-10-21 NO NO803136A patent/NO159019C/no unknown
- 1980-10-21 AU AU63548/80A patent/AU519578B2/en not_active Ceased
- 1980-10-21 ZA ZA00806452A patent/ZA806452B/xx unknown
- 1980-10-21 BE BE0/202544A patent/BE885812A/fr not_active IP Right Cessation
- 1980-10-21 PT PT71946A patent/PT71946B/pt unknown
- 1980-10-21 IE IE2174/80A patent/IE51026B1/en unknown
- 1980-10-21 HU HU802552A patent/HU183236B/hu not_active IP Right Cessation
- 1980-10-21 FI FI803311A patent/FI71156C/fi not_active IP Right Cessation
- 1980-10-21 SU SU802999190A patent/SU1122227A3/ru active
- 1980-10-21 KR KR1019800004041A patent/KR840000797B1/ko not_active Expired
- 1980-10-21 FR FR8022477A patent/FR2467852A1/fr active Granted
- 1980-10-21 BG BG061372A patent/BG38639A3/xx unknown
- 1980-10-21 BG BG049416A patent/BG35189A3/xx unknown
- 1980-10-21 IT IT25488/80A patent/IT1149259B/it active
- 1980-10-21 MX MX809112U patent/MX6094E/es unknown
- 1980-10-22 RO RO102404A patent/RO81225B/ro unknown
- 1980-10-22 DD DD80224691A patent/DD154542A5/de unknown
- 1980-10-22 NL NLAANVRAGE8005810,A patent/NL183358C/xx not_active IP Right Cessation
- 1980-10-22 LU LU82880A patent/LU82880A1/fr unknown
- 1980-10-22 ES ES496166A patent/ES496166A0/es active Granted
- 1980-10-22 CH CH788180A patent/CH646175A5/fr not_active IP Right Cessation
- 1980-10-22 RO RO108549A patent/RO86176B/ro unknown
1981
- 1981-06-05 CS CS814222A patent/CS219292B2/cs unknown
- 1981-08-26 SU SU813325756A patent/SU1026654A3/ru active
- 1981-11-06 PH PH26450A patent/PH17458A/en unknown
- 1981-11-06 PH PH26451A patent/PH18316A/en unknown
- 1981-11-06 PH PH26448A patent/PH17315A/en unknown
- 1981-11-06 PH PH26449A patent/PH17317A/en unknown
1982
- 1982-01-13 AT AT0010882A patent/AT374479B/de not_active IP Right Cessation
- 1982-12-17 CA CA000418062A patent/CA1163924A/en not_active Expired
1983
- 1983-03-21 YU YU671/83A patent/YU42075B/xx unknown
- 1983-06-21 GB GB08316830A patent/GB2129421B/en not_active Expired
- 1983-06-21 GB GB08316829A patent/GB2128986B/en not_active Expired
1984
- 1984-03-06 CH CH1089/84A patent/CH647242A5/fr not_active IP Right Cessation
1986
- 1986-02-06 JP JP61024914A patent/JPS61178988A/ja active Pending

Also Published As

Publication number	Publication date
JPS6135197B2 (de)	1986-08-12
SE8007354L (sv)	1981-04-23
PL129638B1 (en)	1984-05-31
MX6094E (es)	1984-11-12
NO159019C (no)	1988-11-23
IE51027B1 (en)	1986-09-17
RO86176A (ro)	1985-03-15
GB2128986A (en)	1984-05-10
AT369372B (de)	1982-12-27
YU42075B (en)	1988-04-30
GB2129421B (en)	1984-11-14
DD154542A5 (de)	1982-03-31
GB2061930A (en)	1981-05-20
IN154918B (de)	1984-12-22
IE852229L (en)	1981-04-22
JPS61178988A (ja)	1986-08-11
SE451455B (sv)	1987-10-12
JPS5665892A (en)	1981-06-03
PH16219A (en)	1983-08-09
PL235907A1 (de)	1982-09-13
AR227164A1 (es)	1982-09-30
YU267680A (en)	1983-09-30
IE51028B1 (en)	1986-09-17
IE802174L (en)	1981-04-22
SU1122227A3 (ru)	1984-10-30
GB8316829D0 (en)	1983-07-27
BE885812A (fr)	1981-04-21
PT71946A (en)	1980-11-01
NO159019B (no)	1988-08-15
GT198065892A (es)	1982-04-10
DE3039504C2 (de)	1984-10-11
PT71946B (en)	1981-08-31
PL129534B1 (en)	1984-05-31
FI71156B (fi)	1986-08-14
LU82880A1 (fr)	1981-06-04
PH17458A (en)	1984-08-29
GB2061930B (en)	1984-06-13
ES8204437A1 (es)	1982-05-01
YU41743B (en)	1987-12-31
IE51026B1 (en)	1986-09-17
CH646175A5 (fr)	1984-11-15
NL183358B (nl)	1988-05-02
NO803136L (no)	1981-04-23
SU1026654A3 (ru)	1983-06-30
ZA806452B (en)	1981-10-28
PH18316A (en)	1985-05-29
CA1144159A (en)	1983-04-05
NZ195307A (en)	1984-08-24
IT1149259B (it)	1986-12-03
AT374479B (de)	1984-04-25
CA1163924A (en)	1984-03-20
HU183236B (en)	1984-04-28
BG38639A3 (en)	1986-01-15
GB8316830D0 (en)	1983-07-27
BG35189A3 (en)	1984-02-15
DK389480A (da)	1981-04-23
RO81225A (ro)	1983-02-15
US4287181A (en)	1981-09-01
IE850293L (en)	1981-04-22
ES496166A0 (es)	1982-05-01
FR2467852B1 (de)	1983-10-07
CS219292B2 (en)	1983-03-25
FI803311L (fi)	1981-04-23
IL61307A (en)	1984-03-30
NL8005810A (nl)	1981-04-24
IL61307A0 (en)	1980-12-31
GB2129421A (en)	1984-05-16
AU519578B2 (en)	1981-12-10
PL227420A1 (de)	1982-08-30
FI71156C (fi)	1986-11-24
GB2128986B (en)	1985-06-19
PH17317A (en)	1984-07-20
FR2467852A1 (fr)	1981-04-30
RO81225B (ro)	1983-02-28
CS219291B2 (en)	1983-03-25
CH647242A5 (fr)	1985-01-15
AU6354880A (en)	1981-04-30
DE3039504A1 (de)	1981-04-30
GR70714B (de)	1983-01-18
IT8025488A0 (it)	1980-10-21
PH17315A (en)	1984-07-20
ATA518580A (de)	1982-05-15
KR830004309A (ko)	1983-07-09
RO86176B (ro)	1985-03-31
NL183358C (nl)	1988-10-03
KR840000797B1 (ko)	1984-06-12
YU67183A (en)	1984-02-29

Legal Events

Date	Code	Title
1985-05-15	UEP	Publication of translation of european patent specification
1987-12-15	EEFA	Change of the company name
1992-03-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
ATA10882A (de)	1983-09-15	Verfahren zur herstellung von neuen 6betahydroxyalkylpenicillansaeurederivaten
AT375078B (de)	1984-06-25	Verfahren zur herstellung von neuen indolizinderivaten
AT380259B (de)	1986-05-12	Verfahren zur herstellung von neuen peptidamiden
ATA427680A (de)	1983-12-15	Verfahren zur herstellung von neuen 6-pyridazinonen
AT368509B (de)	1982-10-25	Verfahren zur herstellung von neuen 3-vinylcephalosporinen
AT369375B (de)	1982-12-27	Verfahren zur herstellung von neuen 3-vinylcephalosporin-derivaten
AT373259B (de)	1984-01-10	Verfahren zur herstellung von neuen 1oxadethiacephalosporin-derivaten
AT380255B (de)	1986-05-12	Verfahren zur herstellung von neuen benzo-as-triazin-derivaten
AT373595B (de)	1984-02-10	Verfahren zur herstellung von neuen chinazolinen
AT368511B (de)	1982-10-25	Verfahren zur herstellung von neuen cephalosporinantibiotika
AT374798B (de)	1984-05-25	Verfahren zur herstellung von neuen aminoisochinolinderivaten
AT370725B (de)	1983-04-25	Verfahren zur herstellung von neuen 16-methoxy-16-methyl-prostaglandin-e1-derivaten
AT372077B (de)	1983-08-25	Verfahren zur herstellung von neuen benzylidenderivaten
AT372947B (de)	1983-11-25	Verfahren zur herstellung von neuen trans-6oxodecahydrochinolinen
AT369378B (de)	1982-12-27	Verfahren zur herstellung von neuen 3-thiovinyl-cephalosporinderivaten
AT374481B (de)	1984-04-25	Verfahren zur herstellung von neuen 3-thiovinylcephalosporinderivaten
AT378534B (de)	1985-08-26	Verfahren zur herstellung von neuen ergopeptinderivaten
AT375648B (de)	1984-08-27	Verfahren zur herstellung von neuen carbostyrilderivaten
AT374167B (de)	1984-03-26	Verfahren zur herstellung von neuen naphthacenderivaten
AT374480B (de)	1984-04-25	Verfahren zur herstellung von neuen 3-thiovinylcephalosporinderivaten
ATA246483A (de)	1984-02-15	Verfahren zur herstellung von neuen carbostyrilderivaten
ATA451583A (de)	1986-06-15	Verfahren zur herstellung von neuen 1-phenaethylimidazol-derivaten
ATA52583A (de)	1984-11-15	Verfahren zur herstellung von neuen ergopeptinderivaten
ATA365181A (de)	1982-07-15	Verfahren zur herstellung von neuen acylaminobenzoesaeurederivaten
ATA246583A (de)	1984-03-15	Verfahren zur herstellung von neuen carbostyrilderivaten