ATA254886A - Verfahren zur herstellung von neuen mitomycin-c-analogen - Google Patents

Verfahren zur herstellung von neuen mitomycin-c-analogen

Info

Publication number: ATA254886A
Authority: AT; Austria
Prior art keywords: analogs; producing new; mitomycin; new mitomycin; producing
Prior art date: 1985-09-23

Application number

AT0254886A

Other languages

English (en)

Other versions

AT394725B (de

Original Assignee

Bristol Myers Squibb Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-09-23

Filing date

1986-09-23

Publication date

1991-11-15

1986-09-23 Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co

1991-11-15 Publication of ATA254886A publication Critical patent/ATA254886A/de

1992-06-10 Application granted granted Critical

1992-06-10 Publication of AT394725B publication Critical patent/AT394725B/de

Links

NWIBSHFKIJFRCO-WUDYKRTCSA-N Mytomycin Chemical class C1N2C(C(C(C)=C(N)C3=O)=O)=C3[C@@H](COC(N)=O)[C@@]2(OC)[C@@H]2[C@H]1N2 NWIBSHFKIJFRCO-WUDYKRTCSA-N 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyridine Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

AT0254886A 1985-09-23 1986-09-23 Verfahren zur herstellung von neuen mitomycin-c-analogen AT394725B (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US06/781,076 US4866180A (en)	1984-02-24	1985-09-23	Amino disulfide thiol exchange products

Publications (2)

Publication Number	Publication Date
ATA254886A true ATA254886A (de)	1991-11-15
AT394725B AT394725B (de)	1992-06-10

Family

ID=25121607

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT0254886A AT394725B (de)	1985-09-23	1986-09-23	Verfahren zur herstellung von neuen mitomycin-c-analogen

Country Status (10)

Country	Link
US (1)	US4866180A (de)
KR (1)	KR940006629B1 (de)
AT (1)	AT394725B (de)
CA (1)	CA1288106C (de)
ES (1)	ES2001978A6 (de)
FI (1)	FI863776A7 (de)
GR (1)	GR862416B (de)
LU (1)	LU86600A1 (de)
PT (1)	PT83418B (de)
ZA (1)	ZA866297B (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5175303A (en) *	1990-03-08	1992-12-29	Bristol-Myers Squibb Company	Preparation of 7-(diphenylmethyl)oxy-9A-methoxymitosane
US5629427A (en) *	1993-08-26	1997-05-13	Peterson; Dwight M.	2,7-diaminomitosene analogues
ATE427948T1 (de)	2001-04-24	2009-04-15	Purdue Research Foundation	Folat-mimetika und deren folatrezeptorbindende konjugate
CA2484640C (en) *	2002-05-15	2012-01-17	Endocyte, Inc.	Vitamin-mitomycin conjugates
WO2004069159A2 (en)	2003-01-27	2004-08-19	Endocyte, Inc.	Vitamin receptor binding drug delivery conjugates
CN101098854B (zh) *	2004-07-23	2012-12-05	恩多塞特公司	二价连接体及其轭合物
CN101175757B (zh) *	2005-03-16	2012-11-14	恩多塞特公司	蝶酸及其缀合物的合成和纯化
BRPI0615354A2 (pt) *	2005-08-19	2011-05-17	Endocyte, Inc.	conjugado de liberação de fármaco de ligação de receptor, composição farmacêutica que o compreende, bem como seu uso
EP2382995A3 (de) *	2005-08-19	2013-09-25	Endocyte, Inc.	Ligandenkonjugate von Vincaalkaloiden, Analoga und Derivaten
US20100104626A1 (en) *	2007-02-16	2010-04-29	Endocyte, Inc.	Methods and compositions for treating and diagnosing kidney disease
AU2008224988A1 (en) *	2007-03-14	2008-09-18	Endocyte, Inc.	Binding ligand linked drug delivery conjugates of tubulysins
US9877965B2 (en)	2007-06-25	2018-01-30	Endocyte, Inc.	Vitamin receptor drug delivery conjugates for treating inflammation
CN101784565B (zh)	2007-06-25	2014-12-10	恩多塞特公司	含有亲水性间隔区接头的共轭物
CN101909441B (zh)	2007-10-25	2015-05-13	恩多塞特公司	微管蛋白抑制剂及其制备方法
US10080805B2 (en)	2012-02-24	2018-09-25	Purdue Research Foundation	Cholecystokinin B receptor targeting for imaging and therapy
US20140080175A1 (en)	2012-03-29	2014-03-20	Endocyte, Inc.	Processes for preparing tubulysin derivatives and conjugates thereof
BR112015008365A2 (pt)	2012-10-16	2017-07-04	Endocyte Inc	composto da fórmula b-l(d)x, ou um sal farmaceuticamente aceitável do mesmo, composição farmacêutica, uso de um composto, composição de forma de dosagem unitária ou dose unitária, composição para tratar um câncer em um paciente, e método para tratar um câncer em um paciente

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3660578A (en) *	1957-04-06	1972-05-02	Kyowa Hakko Kogyo Kk	Mitomycin c
NL129868C (de) *	1963-06-07
DE1570029A1 (de) *	1964-07-09	1970-04-09	Kyowa Hakko Kogyo Kk	Verfahren zur Herstellung von Mitosanverbindungen
US3420846A (en) *	1964-08-25	1969-01-07	Kyowa Hakko Kogyo Kk	7-substituted mitomycin a
US3332944A (en) *	1964-11-02	1967-07-25	American Cyanamid Co	Antibiotic derivatives of mitomycins a, b, c and porfiromycin
JPS5439098A (en) *	1977-08-31	1979-03-24	Kyowa Hakko Kogyo Co Ltd	Mitomycin c derivatives
US4268676A (en) *	1979-12-05	1981-05-19	University Patents, Inc.	Mitomycin analogs
GB2093643A (en) *	1981-02-17	1982-09-02	Standard Telephones Cables Ltd	DC-to-DC converter
EP0116208B1 (de) *	1982-12-07	1988-03-30	Kyowa Hakko Kogyo Co., Ltd.	Mitomycin-Analoge
US4803212A (en) *	1983-04-11	1989-02-07	Bristol-Myers Company	Amino disulfides
JPS60255789A (ja) *	1984-06-01	1985-12-17	Kyowa Hakko Kogyo Co Ltd	マイトマイシン誘導体，その製造法および抗腫瘍剤

1985
- 1985-09-23 US US06/781,076 patent/US4866180A/en not_active Expired - Fee Related
1986
- 1986-08-20 ZA ZA866297A patent/ZA866297B/xx unknown
- 1986-08-20 CA CA000516372A patent/CA1288106C/en not_active Expired - Fee Related
- 1986-09-18 FI FI863776A patent/FI863776A7/fi not_active Application Discontinuation
- 1986-09-22 PT PT83418A patent/PT83418B/pt not_active IP Right Cessation
- 1986-09-22 GR GR862416A patent/GR862416B/el unknown
- 1986-09-22 ES ES8602078A patent/ES2001978A6/es not_active Expired
- 1986-09-22 LU LU86600A patent/LU86600A1/fr unknown
- 1986-09-23 AT AT0254886A patent/AT394725B/de not_active IP Right Cessation
- 1986-09-23 KR KR1019860007921A patent/KR940006629B1/ko not_active Expired - Fee Related

Also Published As

Publication number	Publication date
CA1288106C (en)	1991-08-27
ZA866297B (en)	1987-04-29
PT83418B (pt)	1989-05-12
FI863776A0 (fi)	1986-09-18
FI863776L (fi)	1987-03-24
LU86600A1 (fr)	1987-04-02
KR870003111A (ko)	1987-04-15
KR940006629B1 (ko)	1994-07-23
FI863776A7 (fi)	1987-03-24
ES2001978A6 (es)	1988-07-01
AT394725B (de)	1992-06-10
PT83418A (en)	1986-10-01
US4866180A (en)	1989-09-12
GR862416B (en)	1987-01-26

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Legal Events

Date	Code	Title	Description
1999-07-15	ELJ	Ceased due to non-payment of the annual fee