ATA254886A - Verfahren zur herstellung von neuen mitomycin-c-analogen - Google Patents

Verfahren zur herstellung von neuen mitomycin-c-analogen

Info

Publication number: ATA254886A
Authority: AT; Austria
Prior art keywords: analogs; producing new; mitomycin; new mitomycin; producing
Prior art date: 1985-09-23

Application number

AT0254886A

Other languages

English (en)

Other versions

AT394725B (de

Original Assignee

Bristol Myers Squibb Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-09-23

Filing date

1986-09-23

Publication date

1991-11-15

1986-09-23 Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co

1991-11-15 Publication of ATA254886A publication Critical patent/ATA254886A/de

1992-06-10 Application granted granted Critical

1992-06-10 Publication of AT394725B publication Critical patent/AT394725B/de

Links

NWIBSHFKIJFRCO-WUDYKRTCSA-N Mytomycin Chemical class C1N2C(C(C(C)=C(N)C3=O)=O)=C3[C@@H](COC(N)=O)[C@@]2(OC)[C@@H]2[C@H]1N2 NWIBSHFKIJFRCO-WUDYKRTCSA-N 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyridine Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

AT0254886A 1985-09-23 1986-09-23 Verfahren zur herstellung von neuen mitomycin-c-analogen AT394725B (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US06/781,076 US4866180A (en)	1984-02-24	1985-09-23	Amino disulfide thiol exchange products

Publications (2)

Publication Number	Publication Date
ATA254886A true ATA254886A (de)	1991-11-15
AT394725B AT394725B (de)	1992-06-10

Family

ID=25121607

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT0254886A AT394725B (de)	1985-09-23	1986-09-23	Verfahren zur herstellung von neuen mitomycin-c-analogen

Country Status (10)

Country	Link
US (1)	US4866180A (de)
KR (1)	KR940006629B1 (de)
AT (1)	AT394725B (de)
CA (1)	CA1288106C (de)
ES (1)	ES2001978A6 (de)
FI (1)	FI863776L (de)
GR (1)	GR862416B (de)
LU (1)	LU86600A1 (de)
PT (1)	PT83418B (de)
ZA (1)	ZA866297B (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5175303A (en) *	1990-03-08	1992-12-29	Bristol-Myers Squibb Company	Preparation of 7-(diphenylmethyl)oxy-9A-methoxymitosane
US5629427A (en) *	1993-08-26	1997-05-13	Peterson; Dwight M.	2,7-diaminomitosene analogues
ATE427948T1 (de) *	2001-04-24	2009-04-15	Purdue Research Foundation	Folat-mimetika und deren folatrezeptorbindende konjugate
EP1504010B1 (de) *	2002-05-15	2009-03-25	Endocyte, Inc.	Vitamin-mitomycin-konjugate
EP2517730A3 (de)	2003-01-27	2013-01-02	Endocyte, Inc.	Vitaminrezeptorbindende Wirkstofffreisetzungskonjugate
US8288557B2 (en) *	2004-07-23	2012-10-16	Endocyte, Inc.	Bivalent linkers and conjugates thereof
JP5289935B2 (ja) *	2005-03-16	2013-09-11	エンドサイト，インコーポレイテッド	プテロイン酸およびその結合体の合成と精製
EP2382995A3 (de) *	2005-08-19	2013-09-25	Endocyte, Inc.	Ligandenkonjugate von Vincaalkaloiden, Analoga und Derivaten
US8465724B2 (en) *	2005-08-19	2013-06-18	Endocyte, Inc.	Multi-drug ligand conjugates
US20100104626A1 (en) *	2007-02-16	2010-04-29	Endocyte, Inc.	Methods and compositions for treating and diagnosing kidney disease
CN101678124A (zh) *	2007-03-14	2010-03-24	恩多塞特公司	结合配体连接的微管溶素递药缀合物
CN101784565B (zh) *	2007-06-25	2014-12-10	恩多塞特公司	含有亲水性间隔区接头的共轭物
US9877965B2 (en)	2007-06-25	2018-01-30	Endocyte, Inc.	Vitamin receptor drug delivery conjugates for treating inflammation
CA2703491C (en)	2007-10-25	2017-06-13	Endocyte, Inc.	Tubulysins and processes for preparing
WO2013126797A1 (en)	2012-02-24	2013-08-29	Purdue Research Foundation	Cholecystokinin b receptor targeting for imaging and therapy
US20140080175A1 (en)	2012-03-29	2014-03-20	Endocyte, Inc.	Processes for preparing tubulysin derivatives and conjugates thereof
AU2013331440A1 (en)	2012-10-16	2015-04-30	Endocyte, Inc.	Drug delivery conjugates containing unnatural amino acids and methods for using

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3660578A (en) *	1957-04-06	1972-05-02	Kyowa Hakko Kogyo Kk	Mitomycin c
NL129868C (de) *	1963-06-07
DE1570029A1 (de) *	1964-07-09	1970-04-09	Kyowa Hakko Kogyo Kk	Verfahren zur Herstellung von Mitosanverbindungen
US3420846A (en) *	1964-08-25	1969-01-07	Kyowa Hakko Kogyo Kk	7-substituted mitomycin a
US3332944A (en) *	1964-11-02	1967-07-25	American Cyanamid Co	Antibiotic derivatives of mitomycins a, b, c and porfiromycin
JPS5439098A (en) *	1977-08-31	1979-03-24	Kyowa Hakko Kogyo Co Ltd	Mitomycin c derivatives
US4268676A (en) *	1979-12-05	1981-05-19	University Patents, Inc.	Mitomycin analogs
GB2093643A (en) *	1981-02-17	1982-09-02	Standard Telephones Cables Ltd	DC-to-DC converter
DE116208T1 (de) *	1982-12-07	1985-02-28	Kyowa Hakko Kogyo Co., Ltd., Tokio/Tokyo	Mitomycin-analoge.
US4803212A (en) *	1983-04-11	1989-02-07	Bristol-Myers Company	Amino disulfides
JPS60255789A (ja) *	1984-06-01	1985-12-17	Kyowa Hakko Kogyo Co Ltd	マイトマイシン誘導体，その製造法および抗腫瘍剤

1985
- 1985-09-23 US US06/781,076 patent/US4866180A/en not_active Expired - Fee Related
1986
- 1986-08-20 CA CA000516372A patent/CA1288106C/en not_active Expired - Fee Related
- 1986-08-20 ZA ZA866297A patent/ZA866297B/xx unknown
- 1986-09-18 FI FI863776A patent/FI863776L/fi not_active Application Discontinuation
- 1986-09-22 PT PT83418A patent/PT83418B/pt not_active IP Right Cessation
- 1986-09-22 GR GR862416A patent/GR862416B/el unknown
- 1986-09-22 ES ES8602078A patent/ES2001978A6/es not_active Expired
- 1986-09-22 LU LU86600A patent/LU86600A1/fr unknown
- 1986-09-23 KR KR1019860007921A patent/KR940006629B1/ko not_active Expired - Fee Related
- 1986-09-23 AT AT0254886A patent/AT394725B/de not_active IP Right Cessation

Also Published As

Publication number	Publication date
GR862416B (en)	1987-01-26
KR870003111A (ko)	1987-04-15
ES2001978A6 (es)	1988-07-01
US4866180A (en)	1989-09-12
FI863776A7 (fi)	1987-03-24
PT83418A (en)	1986-10-01
KR940006629B1 (ko)	1994-07-23
CA1288106C (en)	1991-08-27
LU86600A1 (fr)	1987-04-02
ZA866297B (en)	1987-04-29
FI863776L (fi)	1987-03-24
AT394725B (de)	1992-06-10
FI863776A0 (fi)	1986-09-18
PT83418B (pt)	1989-05-12

Similar Documents

Publication	Publication Date	Title
ATA20485A (de)	1990-08-15	Verfahren zur herstellung von neuen tetrahydrocarbazol-derivaten
ATA28687A (de)	1991-09-15	Verfahren zur herstellung von neuen dichloranilinderivaten
ATA193185A (de)	1991-09-15	Verfahren zur herstellung von neuen substituierten benzamiden
ATA254886A (de)	1991-11-15	Verfahren zur herstellung von neuen mitomycin-c-analogen
AT382156B (de)	1987-01-26	Verfahren zur herstellung von neuen cyclischen 9'-thiapeptidergotalkaloiden
AT382638B (de)	1987-03-25	Verfahren zur herstellung von neuen trehaloselipiden
ATA206483A (de)	1991-12-15	Verfahren zur herstellung von neuen mitosanderivaten
ATA125383A (de)	1986-05-15	Verfahren zur herstellung von neuen benzoazacycloalkyl-spiro-imidazolidinen
AT386197B (de)	1988-07-11	Verfahren zur herstellung von neuen indolderivaten
ATA5985A (de)	1990-03-15	Verfahren zur herstellung von neuen 8alpha-acylaminoergolinen
ATA144987A (de)	1990-11-15	Verfahren zur herstellung von neuen anthracyclinglykosiden
ATA53886A (de)	1993-01-15	Verfahren zur herstellung von chlordioxid
AT385035B (de)	1988-02-10	Verfahren zur herstellung von neuen ergolinderivaten
ATA273486A (de)	1992-09-15	Verfahren zur herstellung von neuen dichloranilinderivaten
AT384218B (de)	1987-10-12	Verfahren zur herstellung von neuen chinazolin-derivaten
ATA258985A (de)	1991-11-15	Verfahren zur herstellung von neuen substituierten 7-oxomitosanen
ATA298586A (de)	1989-11-15	Verfahren zur herstellung von neuen anthracyclinglykosiden
ATA313686A (de)	1993-06-15	Verfahren zur herstellung von neuen carbapenemderivaten
AT386407B (de)	1988-08-25	Verfahren zur herstellung von neuen n-sulfamyl -3-halogenpropionamidinen
ATA52285A (de)	1988-11-15	Verfahren zur herstellung von neuen diazepinoindolen
ATA284985A (de)	1992-02-15	Verfahren zur herstellung von neuen carbapenemderivaten
ATA230583A (de)	1990-11-15	Verfahren zur herstellung von neuen saeurederivaten
AT386408B (de)	1988-08-25	Verfahren zur herstellung von neuen thioalkanoyl- carnitinen
ATA223986A (de)	1991-07-15	Verfahren zur herstellung von neuen dihydropyridinderivaten
ATA168486A (de)	1989-11-15	Verfahren zur herstellung von neuen 2-halogen-nicergolinen

Legal Events

Date	Code	Title	Description
1999-07-15	ELJ	Ceased due to non-payment of the annual fee