LU86600A1 - Produits d'echange entre un aminodisulfure et un thiol - Google Patents

Produits d'echange entre un aminodisulfure et un thiol Download PDF

Info

Publication number
LU86600A1
LU86600A1 LU86600A LU86600A LU86600A1 LU 86600 A1 LU86600 A1 LU 86600A1 LU 86600 A LU86600 A LU 86600A LU 86600 A LU86600 A LU 86600A LU 86600 A1 LU86600 A1 LU 86600A1
Authority
LU
Luxembourg
Prior art keywords
compound
identified
compound according
amino
substituted
Prior art date
Application number
LU86600A
Other languages
English (en)
French (fr)
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of LU86600A1 publication Critical patent/LU86600A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
LU86600A 1985-09-23 1986-09-22 Produits d'echange entre un aminodisulfure et un thiol LU86600A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US78107685 1985-09-23
US06/781,076 US4866180A (en) 1984-02-24 1985-09-23 Amino disulfide thiol exchange products

Publications (1)

Publication Number Publication Date
LU86600A1 true LU86600A1 (fr) 1987-04-02

Family

ID=25121607

Family Applications (1)

Application Number Title Priority Date Filing Date
LU86600A LU86600A1 (fr) 1985-09-23 1986-09-22 Produits d'echange entre un aminodisulfure et un thiol

Country Status (10)

Country Link
US (1) US4866180A (de)
KR (1) KR940006629B1 (de)
AT (1) AT394725B (de)
CA (1) CA1288106C (de)
ES (1) ES2001978A6 (de)
FI (1) FI863776A7 (de)
GR (1) GR862416B (de)
LU (1) LU86600A1 (de)
PT (1) PT83418B (de)
ZA (1) ZA866297B (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5175303A (en) * 1990-03-08 1992-12-29 Bristol-Myers Squibb Company Preparation of 7-(diphenylmethyl)oxy-9A-methoxymitosane
US5629427A (en) * 1993-08-26 1997-05-13 Peterson; Dwight M. 2,7-diaminomitosene analogues
EP1389209B1 (de) * 2001-04-24 2009-04-08 Purdue Research Foundation Folat-mimetika und deren folatrezeptorbindende konjugate
KR20040106547A (ko) 2002-05-15 2004-12-17 엔도사이트, 인코포레이티드 비타민-마이토마이신 공액체
US7601332B2 (en) 2003-01-27 2009-10-13 Endocyte, Inc. Vitamin receptor binding drug delivery conjugates
CN101098854B (zh) 2004-07-23 2012-12-05 恩多塞特公司 二价连接体及其轭合物
CN101175757B (zh) * 2005-03-16 2012-11-14 恩多塞特公司 蝶酸及其缀合物的合成和纯化
JP2009504783A (ja) * 2005-08-19 2009-02-05 エンドサイト，インコーポレイテッド ビンカアルカロイド、類似体および誘導体のリガンド結合体
RU2470668C2 (ru) * 2005-08-19 2012-12-27 Эндосайт, Инк. Конъюгаты лиганда с несколькими лекарственными средствами
US20100104626A1 (en) * 2007-02-16 2010-04-29 Endocyte, Inc. Methods and compositions for treating and diagnosing kidney disease
CN104127878A (zh) * 2007-03-14 2014-11-05 恩多塞特公司 结合配体连接的微管溶素递药缀合物
BRPI0812970A2 (pt) * 2007-06-25 2019-09-24 Endocyte Inc conjugados contendo espaçadores hidrofílicos
US9877965B2 (en) 2007-06-25 2018-01-30 Endocyte, Inc. Vitamin receptor drug delivery conjugates for treating inflammation
EP2209374B1 (de) 2007-10-25 2014-12-03 Endocyte, Inc. Tubulysine und verfahren zu ihrer herstellung
WO2013126797A1 (en) 2012-02-24 2013-08-29 Purdue Research Foundation Cholecystokinin b receptor targeting for imaging and therapy
US20140080175A1 (en) 2012-03-29 2014-03-20 Endocyte, Inc. Processes for preparing tubulysin derivatives and conjugates thereof
EA201590622A1 (ru) 2012-10-16 2015-10-30 Эндосайт, Инк. Конъюгаты для доставки лекарственного средства, содержащие не встречающиеся в природе аминокислоты, и способы применения

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3660578A (en) * 1957-04-06 1972-05-02 Kyowa Hakko Kogyo Kk Mitomycin c
NL129868C (de) * 1963-06-07
DE1570029A1 (de) * 1964-07-09 1970-04-09 Kyowa Hakko Kogyo Kk Verfahren zur Herstellung von Mitosanverbindungen
US3420846A (en) * 1964-08-25 1969-01-07 Kyowa Hakko Kogyo Kk 7-substituted mitomycin a
US3332944A (en) * 1964-11-02 1967-07-25 American Cyanamid Co Antibiotic derivatives of mitomycins a, b, c and porfiromycin
JPS5439098A (en) * 1977-08-31 1979-03-24 Kyowa Hakko Kogyo Co Ltd Mitomycin c derivatives
US4268676A (en) * 1979-12-05 1981-05-19 University Patents, Inc. Mitomycin analogs
GB2093643A (en) * 1981-02-17 1982-09-02 Standard Telephones Cables Ltd DC-to-DC converter
EP0116208B1 (de) * 1982-12-07 1988-03-30 Kyowa Hakko Kogyo Co., Ltd. Mitomycin-Analoge
US4803212A (en) * 1983-04-11 1989-02-07 Bristol-Myers Company Amino disulfides
JPS60255789A (ja) * 1984-06-01 1985-12-17 Kyowa Hakko Kogyo Co Ltd マイトマイシン誘導体，その製造法および抗腫瘍剤

Also Published As

Publication number Publication date
US4866180A (en) 1989-09-12
FI863776L (fi) 1987-03-24
AT394725B (de) 1992-06-10
ZA866297B (en) 1987-04-29
KR870003111A (ko) 1987-04-15
PT83418B (pt) 1989-05-12
ES2001978A6 (es) 1988-07-01
GR862416B (en) 1987-01-26
PT83418A (en) 1986-10-01
ATA254886A (de) 1991-11-15
CA1288106C (en) 1991-08-27
FI863776A0 (fi) 1986-09-18
KR940006629B1 (ko) 1994-07-23
FI863776A7 (fi) 1987-03-24

Similar Documents

Publication Publication Date Title
EP0116208B1 (de) Mitomycin-Analoge
EP0280741B1 (de) Mitomycin-derivate
US4866180A (en) Amino disulfide thiol exchange products
HK1001329B (en) Mitomycin derivatives
US6306849B1 (en) Selected derivatives of K-252a
LU84843A1 (fr) Amidines
HK131897A (en) Disulfur analogs of LL-E33288 antitumor agents
LU85295A1 (fr) Aminodisulfures
US4814445A (en) Process for preparing mitomycin analogs
LU85711A1 (fr) Acylaminomitosanes
CA1291293C (en) Substituted 7-oxomitosanes
JP2991348B2 (ja) ７−（ジフェニルメチル）オキシ−９ａ−メトキシマイトサン並びにその製造及び使用
FR2517680A1 (fr) Derives n-(vinblastinoyl-23) d'acides amines, leur preparation et leur application therapeutique
BE899380A (fr) Aminodisulfures.
US4927943A (en) Substituted 7-oxomitosanes
US5106840A (en) Method of preparing n-oxo-tetrahydro-beta-carbolines
LU86411A1 (fr) Procede de preparation de derives n7-amidino-substitutes de la mitomycine c.
US5318975A (en) 5-pyrimdineamine derivatives
EP0272063B1 (de) Mitomycinderivate
EP0294828B1 (de) Mitomycinanaloge, Verfahren zu ihrer Herstellung und pharmazeutische Zubereitungen
BE896963A (fr) Amidines
EP0412015B1 (de) Derivate von N-(Vincristinyl-23) und N-(Noranhydro-5-vinblastinyl-23) von Amino-1-methylphosphonsäure, ihre Verfahren zur Herstellung und sie enthaltende pharmazeutische Zusammensetzungen
CA1204770A (en) Fluorinated diaminoalkene derivatives
US5099016A (en) Substituted 7-oxomitosanes
US5097036A (en) Substituted 7-oxomitosanes