ATA294786A - Verfahren zur herstellung des hydrochlorids von (2s,3s)-3-acetoxy-5-(2-(n,n-dimethylaminoethyl) -2-(4-methoxyphenyl)-2,3-dihydro-1,5-benzothiazepin-4(5h)-on - Google Patents

Verfahren zur herstellung des hydrochlorids von (2s,3s)-3-acetoxy-5-(2-(n,n-dimethylaminoethyl) -2-(4-methoxyphenyl)-2,3-dihydro-1,5-benzothiazepin-4(5h)-on

Info

Publication number: ATA294786A
Authority: AT; Austria
Prior art keywords: benzothiazepine; acetoxy; dimethylaminoethyl; methoxyphenyl; dihydro
Prior art date: 1985-11-06

Application number

AT862947A

Other languages

English (en)

Other versions

AT393837B (de

Inventor

Tibor Dipl Chem Ing Dr Gizur

Kalman Dipl Chem Ing Harsanyi

Zsuzsanna Dipl Chem Ing Aracs

Jozsef Dipl Chem Ing D Felmeri

Katalin Berki

Aniko Demeter

Ferenc Dr Trischler

Zsuzsanna Vincze

Original Assignee

Richter Gedeon Vegyeszet

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-11-06

Filing date

1986-11-05

Publication date

1991-06-15

1986-11-05 Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet

1991-06-15 Publication of ATA294786A publication Critical patent/ATA294786A/de

1991-12-27 Application granted granted Critical

1991-12-27 Publication of AT393837B publication Critical patent/AT393837B/de

Links

FCUYSFJBRKOICB-UHFFFAOYSA-N 2-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-3,5-dihydro-1,5-benzothiazepin-4-one Chemical compound C1=CC(OC)=CC=C1C1(CCN(C)C)SC2=CC=CC=C2NC(=O)C1 FCUYSFJBRKOICB-UHFFFAOYSA-N 0.000 title 1
VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D281/02—Seven-membered rings
- C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
- C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D281/10—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Cardiology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Heart & Thoracic Surgery (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

AT0294786A 1985-11-06 1986-11-05 Verfahren zur herstellung des hydrochlorids von (2s,3s)-3-acetoxy-5-(2-(n,n-dimethylaminoethyl) -2-(4-methoxyphenyl)-2,3-dihydro-1,5-benzothiaz pin-4(5h)-on AT393837B (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
HU854264A HU195795B (en)	1985-11-06	1985-11-06	Process for preparing (2s,3s)-3-acetoxy-5-(n,n-dimethyl-amino-ethyl)-2-(h-methoxy-phenyl)-2,3-dihydro-1,5-benzothiazepin-h(5h)-one

Publications (2)

Publication Number	Publication Date
ATA294786A true ATA294786A (de)	1991-06-15
AT393837B AT393837B (de)	1991-12-27

Family

ID=10967486

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT0294786A AT393837B (de)	1985-11-06	1986-11-05	Verfahren zur herstellung des hydrochlorids von (2s,3s)-3-acetoxy-5-(2-(n,n-dimethylaminoethyl) -2-(4-methoxyphenyl)-2,3-dihydro-1,5-benzothiaz pin-4(5h)-on

Country Status (6)

Country	Link
JP (1)	JPS62108872A (de)
AT (1)	AT393837B (de)
BE (1)	BE905704A (de)
CA (1)	CA1309714C (de)
ES (1)	ES2001146A6 (de)
HU (1)	HU195795B (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS6450872A (en) *	1987-08-21	1989-02-27	Tanabe Seiyaku Co	Production of 1,5-benzothiazepine derivative
IT1226301B (it) *	1988-07-26	1990-12-27	Zambon Spa	Processo per la preparazione di intermedi per la sintesi del diltiazem.

1985
- 1985-11-06 HU HU854264A patent/HU195795B/hu not_active IP Right Cessation
1986
- 1986-11-05 CA CA000522187A patent/CA1309714C/en not_active Expired - Lifetime
- 1986-11-05 ES ES8602911A patent/ES2001146A6/es not_active Expired
- 1986-11-05 JP JP61263630A patent/JPS62108872A/ja active Granted
- 1986-11-05 AT AT0294786A patent/AT393837B/de not_active IP Right Cessation
- 1986-11-05 BE BE0/217372A patent/BE905704A/fr not_active IP Right Cessation

Also Published As

Publication number	Publication date
ES2001146A6 (es)	1988-04-16
AT393837B (de)	1991-12-27
HUT42767A (en)	1987-08-28
CA1309714C (en)	1992-11-03
JPS62108872A (ja)	1987-05-20
HU195795B (en)	1988-07-28
JPH0354939B2 (de)	1991-08-21
BE905704A (fr)	1987-03-02

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Legal Events

Date	Code	Title	Description
1995-05-15	EIH	Change in the person of patent owner
2006-02-15	ELJ	Ceased due to non-payment of the annual fee