ATA582780A - Verfahren zur herstellung von 1-(8-chinolyl)2-pyrrolidinon und dessen saeureadditionssalzen - Google Patents

Verfahren zur herstellung von 1-(8-chinolyl)2-pyrrolidinon und dessen saeureadditionssalzen

Info

Publication number
ATA582780A
ATA582780A AT0582780A AT582780A ATA582780A AT A582780 A ATA582780 A AT A582780A AT 0582780 A AT0582780 A AT 0582780A AT 582780 A AT582780 A AT 582780A AT A582780 A ATA582780 A AT A582780A
Authority
AT
Austria
Prior art keywords
chinolyl
pyrrolidinone
producing
acid addition
addition salts
Prior art date
Application number
AT0582780A
Other languages
English (en)
Other versions
AT375363B (de
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of ATA582780A publication Critical patent/ATA582780A/de
Application granted granted Critical
Publication of AT375363B publication Critical patent/AT375363B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C07D215/40—Nitrogen atoms attached in position 8
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Catalysts (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT0582780A 1979-11-30 1980-11-28 Verfahren zur herstellung von 1-(8-chinolyl)2-pyrrolidinon und dessen saeureadditionssalzen AT375363B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7941409 1979-11-30

Publications (2)

Publication Number Publication Date
ATA582780A true ATA582780A (de) 1983-12-15
AT375363B AT375363B (de) 1984-07-25

Family

ID=10509524

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0582780A AT375363B (de) 1979-11-30 1980-11-28 Verfahren zur herstellung von 1-(8-chinolyl)2-pyrrolidinon und dessen saeureadditionssalzen

Country Status (18)

Country Link
US (1) US4366158A (de)
EP (1) EP0030023A3 (de)
JP (1) JPS5699475A (de)
KR (1) KR830004293A (de)
AR (1) AR228442A1 (de)
AT (1) AT375363B (de)
AU (1) AU6495080A (de)
CA (1) CA1156235A (de)
DK (1) DK506480A (de)
ES (1) ES8203882A1 (de)
FI (1) FI803704A7 (de)
GB (1) GB2063868B (de)
GR (1) GR71918B (de)
HU (1) HU185224B (de)
IL (1) IL61580A (de)
IT (1) IT1221040B (de)
NZ (1) NZ195688A (de)
ZA (1) ZA807467B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1558582E (pt) 2003-07-22 2006-05-31 Arena Pharm Inc Derivados de diaril- e aril-heteroaril-ureia como moduladores do receptor de serotonina 5-ht2a uteis para a profilaxia e tratamento de desordens relacionadas com o mesmo
GB0507198D0 (en) * 2005-04-08 2005-05-18 Sb Pharmco Inc Process for preparing bicyclic compounds
GB0519758D0 (en) * 2005-09-28 2005-11-09 Glaxo Group Ltd Novel process
EP2508177A1 (de) 2007-12-12 2012-10-10 Glaxo Group Limited Kombinationen mit 3-phenylsulfonyl-8-piperazinyl-1yl-chinolin
WO2009123714A2 (en) 2008-04-02 2009-10-08 Arena Pharmaceuticals, Inc. Processes for the preparation of pyrazole derivatives useful as modulators of the 5-ht2a serotonin receptor
WO2010062321A1 (en) 2008-10-28 2010-06-03 Arena Pharmaceuticals, Inc. Processes useful for the preparation of 1-[3-(4-bromo-2-methyl-2h-pyrazol-3-yl)-4-methoxy-phenyl]-3-(2,4-difluoro-phenyl)-urea and crystalline forms related thereto
WO2016201373A1 (en) 2015-06-12 2016-12-15 Axovant Sciences Ltd. Diaryl and arylheteroaryl urea derivatives useful for the prophylaxis and treatment of rem sleep behavior disorder
WO2017011767A2 (en) 2015-07-15 2017-01-19 Axovant Sciences Ltd. Diaryl and arylheteroaryl urea derivatives as modulators of the 5-ht2a serotonin receptor useful for the prophylaxis and treatment of hallucinations associated with a neurodegenerative disease

Also Published As

Publication number Publication date
GB2063868A (en) 1981-06-10
GB2063868B (en) 1984-02-29
ZA807467B (en) 1982-07-28
DK506480A (da) 1981-05-31
KR830004293A (ko) 1983-07-09
ES497242A0 (es) 1982-04-01
FI803704L (fi) 1981-05-31
HU185224B (en) 1984-12-28
NZ195688A (en) 1984-09-28
AT375363B (de) 1984-07-25
GR71918B (de) 1983-08-17
IL61580A0 (en) 1980-12-31
CA1156235A (en) 1983-11-01
EP0030023A3 (de) 1981-09-02
IL61580A (en) 1984-06-29
FI803704A7 (fi) 1981-05-31
ES8203882A1 (es) 1982-04-01
JPS5699475A (en) 1981-08-10
EP0030023A2 (de) 1981-06-10
IT8050277A0 (it) 1980-11-28
AU6495080A (en) 1981-06-04
AR228442A1 (es) 1983-03-15
IT1221040B (it) 1990-06-21
US4366158A (en) 1982-12-28

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Legal Events

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ELJ Ceased due to non-payment of the annual fee