ATA91797A - Eine das vwf-propeptid enthaltende pharmazeutische präparation - Google Patents

Eine das vwf-propeptid enthaltende pharmazeutische präparation

Info

Publication number
ATA91797A
ATA91797A AT0091797A AT91797A ATA91797A AT A91797 A ATA91797 A AT A91797A AT 0091797 A AT0091797 A AT 0091797A AT 91797 A AT91797 A AT 91797A AT A91797 A ATA91797 A AT A91797A
Authority
AT
Austria
Prior art keywords
pharmaceutical preparation
preparation containing
vwf propeptide
vwf
propeptide
Prior art date
Application number
AT0091797A
Other languages
English (en)
Other versions
AT405485B (de
Inventor
Hans-Peter Schwarz
Katalin Dr Varadi
Peter Dr Turecek
Hendrik Coenraad Hemker
Suzette Lucette Beguin
Original Assignee
Immuno Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to AT0091797A priority Critical patent/AT405485B/de
Application filed by Immuno Ag filed Critical Immuno Ag
Priority to PCT/EP1998/003090 priority patent/WO1998053848A1/en
Priority to JP50022099A priority patent/JP4335978B2/ja
Priority to ES98929378T priority patent/ES2168766T3/es
Priority to EP98929378A priority patent/EP0977584B1/de
Priority to AT98929378T priority patent/ATE210455T1/de
Priority to AU79156/98A priority patent/AU744643B2/en
Priority to CA002288737A priority patent/CA2288737A1/en
Priority to US09/424,498 priority patent/US7005502B1/en
Priority to DE69802918T priority patent/DE69802918T2/de
Publication of ATA91797A publication Critical patent/ATA91797A/de
Application granted granted Critical
Publication of AT405485B publication Critical patent/AT405485B/de
Priority to NO19995843A priority patent/NO324064B1/no
Priority to US11/218,406 priority patent/US7557188B2/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A61K38/37—Factors VIII
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT0091797A 1997-05-28 1997-05-28 Eine das vwf-propeptid enthaltende pharmazeutische präparation AT405485B (de)

Priority Applications (12)

Application Number Priority Date Filing Date Title
AT0091797A AT405485B (de) 1997-05-28 1997-05-28 Eine das vwf-propeptid enthaltende pharmazeutische präparation
US09/424,498 US7005502B1 (en) 1997-05-28 1998-05-26 Pharmaceutical preparation comprising vWF propeptide
ES98929378T ES2168766T3 (es) 1997-05-28 1998-05-26 Preparacion farmaceutica que incluye el propeptido vwf.
EP98929378A EP0977584B1 (de) 1997-05-28 1998-05-26 Vwf propeptide enthaltendes pharmazeutisches präparat
AT98929378T ATE210455T1 (de) 1997-05-28 1998-05-26 Vwf propeptide enthaltendes pharmazeutisches präparat
AU79156/98A AU744643B2 (en) 1997-05-28 1998-05-26 Pharmaceutical preparation comprising vWF propeptide
PCT/EP1998/003090 WO1998053848A1 (en) 1997-05-28 1998-05-26 PHARMACEUTICAL PREPARATION COMPRISING vWF PROPEPTIDE
JP50022099A JP4335978B2 (ja) 1997-05-28 1998-05-26 vWFプロペプチドを含む医薬調製物
DE69802918T DE69802918T2 (de) 1997-05-28 1998-05-26 Vwf propeptide enthaltendes pharmazeutisches präparat
CA002288737A CA2288737A1 (en) 1997-05-28 1998-05-26 Pharmaceutical preparation comprising vwf propeptide
NO19995843A NO324064B1 (no) 1997-05-28 1999-11-29 Farmasoytisk preparat omfattende vWF-propeptid samt fremgangsmate for fremstilling og anvendelse derav
US11/218,406 US7557188B2 (en) 1997-05-28 2005-09-01 Methods of treating blood coagulation disorders using a pharmaceutical preparation comprising vWF propeptide

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT0091797A AT405485B (de) 1997-05-28 1997-05-28 Eine das vwf-propeptid enthaltende pharmazeutische präparation

Publications (2)

Publication Number Publication Date
ATA91797A true ATA91797A (de) 1999-01-15
AT405485B AT405485B (de) 1999-08-25

Family

ID=3502803

Family Applications (2)

Application Number Title Priority Date Filing Date
AT0091797A AT405485B (de) 1997-05-28 1997-05-28 Eine das vwf-propeptid enthaltende pharmazeutische präparation
AT98929378T ATE210455T1 (de) 1997-05-28 1998-05-26 Vwf propeptide enthaltendes pharmazeutisches präparat

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT98929378T ATE210455T1 (de) 1997-05-28 1998-05-26 Vwf propeptide enthaltendes pharmazeutisches präparat

Country Status (10)

Country Link
US (2) US7005502B1 (de)
EP (1) EP0977584B1 (de)
JP (1) JP4335978B2 (de)
AT (2) AT405485B (de)
AU (1) AU744643B2 (de)
CA (1) CA2288737A1 (de)
DE (1) DE69802918T2 (de)
ES (1) ES2168766T3 (de)
NO (1) NO324064B1 (de)
WO (1) WO1998053848A1 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE430578T1 (de) * 1999-12-24 2009-05-15 Chemo Sero Therapeut Res Inst Faktor viii oder von willebrand faktor zur behandlung von thrombopathie assoziierenden hämorrhagischen erkrankungen
JP4663837B2 (ja) * 1999-12-24 2011-04-06 一般財団法人化学及血清療法研究所 第▲viii▼因子を主成分とする血小板減少に伴う出血疾患の予防・治療用医薬組成物
AU2005322067B8 (en) 2004-12-27 2012-07-26 Takeda Pharmaceutical Company Limited Polymer-von Willebrand factor-conjugates
US7645860B2 (en) 2006-03-31 2010-01-12 Baxter Healthcare S.A. Factor VIII polymer conjugates
WO2007126808A1 (en) 2006-03-31 2007-11-08 Baxter International Inc Pegylated factor viii
EP2244814B1 (de) * 2007-12-28 2021-06-02 Takeda Pharmaceutical Company Limited Formulierungen von rekombinantem vwf
US11197916B2 (en) 2007-12-28 2021-12-14 Takeda Pharmaceutical Company Limited Lyophilized recombinant VWF formulations
ES2298096B1 (es) 2008-01-08 2009-01-01 Grifols, S.A. Procedimiento para la obtencion de un concentrado de factor von willebrand o del complejo de factor viii/factor von willebrand y utilizacionde los mismos.
EP2349314B1 (de) 2008-10-21 2013-02-27 Baxter International Inc. Lyophilisierte rekombinante vwf-formulierungen
NZ592905A (en) * 2008-10-27 2012-11-30 Baxter Int Models of thrombotic thrombocytopenic purpura and methods of use thereof
MX2012002129A (es) 2009-08-20 2012-06-08 Baxter Int Purificacion del factor de von willebrand (vwf) para remocion incrementada de virus envueltos sin lipido.
US20110150843A1 (en) * 2009-10-30 2011-06-23 National Institute Of Immunology Method for the therapeutic correction of hemophilia a by transplanting bone marrow cells
US9700486B2 (en) 2013-04-24 2017-07-11 Corning Incorporated Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients
NL2017452A (en) 2015-10-02 2017-04-11 Asml Netherlands Bv Metrology method and apparatus, computer program and lithographic system
JP7326246B2 (ja) 2017-07-07 2023-08-15 武田薬品工業株式会社 待機手術を受ける、重度のフォンヴィレブランド病を患う患者の、組換えvwfの投与による治療法
FI3648788T5 (fi) 2017-07-07 2024-09-09 Takeda Pharmaceuticals Co Maha-suolikanavan verenvuodon hoito vaikeaa von willebrandin tautia sairastavilla potilailla antamalla rekombinanttia vwf:ää
CA3094644A1 (en) 2018-03-21 2019-09-26 Baxalta Incorporated Separation of vwf and vwf propeptide by chromatographic methods
EA202192140A1 (ru) 2019-02-01 2021-12-15 Такеда Фармасьютикал Компани Лимитед СПОСОБЫ ПРОФИЛАКТИЧЕСКОГО ЛЕЧЕНИЯ РЕКОМБИНАНТНЫМ ФВ (рФВ)
JP2022547556A (ja) 2019-09-11 2022-11-14 武田薬品工業株式会社 フォン・ヴィレブランド因子と補体c1qの複合体に関連する治療法
CA3169996A1 (en) 2020-02-04 2021-08-12 Takeda Pharmaceutical Company Limited Treatment of menorrhagia in patients with severe von willebrand disease by administration of recombinant vwf

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT350726B (de) 1976-08-30 1979-06-11 Immuno Ag Verfahren zur herstellung einer blut- gerinnungsfoerdernden praeperation aus menschlichem blutplasma
AT368883B (de) 1980-07-22 1982-11-25 Immuno Ag Verfahren zur herstellung einer neuen blutgerinnungsfoerdernden praeparation auf basis von humanproteinen
US4540573A (en) 1983-07-14 1985-09-10 New York Blood Center, Inc. Undenatured virus-free biologically active protein derivatives
AT378005B (de) 1983-08-20 1985-06-10 Linde Ag Verfahren zum desoxidieren von metallschmelzen
AT389815B (de) 1984-03-09 1990-02-12 Immuno Ag Verfahren zur inaktivierung von vermehrungsfaehigen filtrierbaren krankheitserregern in blutprodukten
US5198349A (en) * 1986-01-03 1993-03-30 Genetics Institute, Inc. Method for producing factor VIII:C and analogs
AT390560B (de) 1986-05-30 1990-05-25 Immuno Ag Verfahren zur inaktivierung von vermehrungsfaehigen filtrierbaren krankheitserregern
US5849536A (en) * 1990-03-02 1998-12-15 Bio-Technology General Corp. Cloning and production of human von willebrand factor GPIb binding domain polypeptides and methods of using same
FR2673632A1 (fr) * 1991-03-08 1992-09-11 Lille Transfusion Sanguine Procede de preparation de concentre de facteur von willebrand humain de tres haute purete, approprie a un usage therapeutique.
AT402891B (de) 1991-06-20 1997-09-25 Immuno Ag Verfahren zur herstellung eines inaktivierten blutproduktes
AT398079B (de) 1991-11-04 1994-09-26 Immuno Ag Präparation mit thrombinaktivität sowie verfahren zu ihrer herstellung
EP0674531A1 (de) 1992-12-16 1995-10-04 IMMUNO Aktiengesellschaft Verfahren zur herstellung eines virussicheren biologischen präparates
AT402788B (de) 1993-08-03 1997-08-25 Immuno Ag Virussichere blutgerinnungsfaktor xiii-präparation
JPH07330797A (ja) * 1994-05-31 1995-12-19 Sumitomo Metal Ind Ltd 新規細胞接着活性ペプチド
DE4437544A1 (de) * 1994-10-20 1996-04-25 Behringwerke Ag Einsatz von vWF-enthaltenden Konzentraten als Kombinationstherapie bei Therapie mit Antithrombotika und Fibrinolytika
AT404359B (de) 1996-04-29 1998-11-25 Immuno Ag Gereinigte multimerase
AT404554B (de) 1996-04-29 1998-12-28 Immuno Ag Pharmazeutische präparation
US6068838A (en) 1996-04-29 2000-05-30 Baxter Aktiengesellschaft Purified multimerase

Also Published As

Publication number Publication date
EP0977584B1 (de) 2001-12-12
NO995843L (no) 2000-01-27
CA2288737A1 (en) 1998-12-03
EP0977584A1 (de) 2000-02-09
AU744643B2 (en) 2002-02-28
NO995843D0 (no) 1999-11-29
JP2001527579A (ja) 2001-12-25
JP4335978B2 (ja) 2009-09-30
US20060003921A1 (en) 2006-01-05
WO1998053848A1 (en) 1998-12-03
US7557188B2 (en) 2009-07-07
DE69802918D1 (de) 2002-01-24
AT405485B (de) 1999-08-25
DE69802918T2 (de) 2003-04-10
ATE210455T1 (de) 2001-12-15
US7005502B1 (en) 2006-02-28
ES2168766T3 (es) 2002-06-16
NO324064B1 (no) 2007-08-06
AU7915698A (en) 1998-12-30

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Legal Events

Date Code Title Description
REN Ceased due to non-payment of the annual fee
EIH Change in the person of patent owner
PC Change of the owner

Owner name: BAXALTA INCORPORATED, US

Effective date: 20160623

Owner name: BAXALTA GMBH, CH

Effective date: 20160623

MK07 Expiry

Effective date: 20170528