ATE100097T1 - Benzoxepin-derivate. - Google Patents

Benzoxepin-derivate.

Info

Publication number
ATE100097T1
ATE100097T1 AT90302745T AT90302745T ATE100097T1 AT E100097 T1 ATE100097 T1 AT E100097T1 AT 90302745 T AT90302745 T AT 90302745T AT 90302745 T AT90302745 T AT 90302745T AT E100097 T1 ATE100097 T1 AT E100097T1
Authority
AT
Austria
Prior art keywords
formula
benzoxepin
chem
derivatives
benzoxepin derivatives
Prior art date
Application number
AT90302745T
Other languages
English (en)
Inventor
Toshio Tatsuoka
Makoto Shibata
Original Assignee
Suntory Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Suntory Ltd filed Critical Suntory Ltd
Application granted granted Critical
Publication of ATE100097T1 publication Critical patent/ATE100097T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrane Compounds (AREA)
AT90302745T 1989-03-15 1990-03-14 Benzoxepin-derivate. ATE100097T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1061040A JP2851054B2 (ja) 1989-03-15 1989-03-15 ベンズオキセピン誘導体

Publications (1)

Publication Number Publication Date
ATE100097T1 true ATE100097T1 (de) 1994-01-15

Family

ID=13159742

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90302745T ATE100097T1 (de) 1989-03-15 1990-03-14 Benzoxepin-derivate.

Country Status (7)

Country Link
US (1) US5041444A (de)
EP (1) EP0388188B1 (de)
JP (1) JP2851054B2 (de)
AT (1) ATE100097T1 (de)
DE (1) DE69005861T2 (de)
DK (1) DK0388188T3 (de)
ES (1) ES2062336T3 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2316832B1 (de) * 2004-08-27 2017-03-08 Infinity Pharmaceuticals, Inc. Cyclopamin Analogverbindungen, deren Herstellungsverfahren und Anwendung
ITMI20042168A1 (it) * 2004-11-12 2005-02-12 Erregierre Spa Processo di preparazione di itopride cloridrato
TWI433674B (zh) 2006-12-28 2014-04-11 Infinity Discovery Inc 環杷明（ｃｙｃｌｏｐａｍｉｎｅ）類似物類
BRPI0808444A2 (pt) 2007-03-07 2017-06-06 Infinity Discovery Inc análogos de ciclopamina lactam e métodos de uso dos mesmos
EP2129677B1 (de) 2007-03-07 2014-12-17 Infinity Discovery, Inc. Heterocyclische cyclopamin-analoga und verfahren zu ihrer verwendung
CN101917853B (zh) 2007-12-27 2014-03-19 无限药品股份有限公司 立体选择性还原的方法
CN101959879B (zh) * 2008-03-01 2014-10-01 默克专利有限公司 用于治疗和预防1型和2型糖尿病的5-氧代-2,3,4,5-四氢-苯并[b]氧杂*-4-甲酸酰胺和2,3-二氢-苯并[b]氧杂*-4-甲酸酰胺
AU2010279325B2 (en) 2009-08-05 2016-10-20 Infinity Pharmaceuticals, Inc. Enzymatic transamination of cyclopamine analogs
US9394313B2 (en) 2010-09-14 2016-07-19 Infinity Pharmaceuticals, Inc. Transfer hydrogenation of cyclopamine analogs
WO2016019587A1 (en) * 2014-08-08 2016-02-11 Merck Sharp & Dohme Corp. [7, 6]-fused bicyclic antidiabetic compounds
US10369147B2 (en) 2015-06-04 2019-08-06 PellePharm, Inc. Topical formulations for delivery of hedgehog inhibitor compounds and use thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4766212A (en) * 1983-02-15 1988-08-23 Merrell Dow Pharmaceuticals Inc. 2H-[1]benzoxepino[5,4-b]-1,4-oxazine derivatives
AU597671B2 (en) * 1986-06-20 1990-06-07 Suntory Limited 2-Phenylbenzoxepin derivative

Also Published As

Publication number Publication date
DE69005861D1 (de) 1994-02-24
EP0388188A1 (de) 1990-09-19
DK0388188T3 (da) 1994-02-14
JPH02243687A (ja) 1990-09-27
US5041444A (en) 1991-08-20
EP0388188B1 (de) 1994-01-12
DE69005861T2 (de) 1994-04-28
JP2851054B2 (ja) 1999-01-27
ES2062336T3 (es) 1994-12-16

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee