ATE100150T1 - Verfahren zur bestimmung von physiologisch wirksamen substanzen. - Google Patents

Verfahren zur bestimmung von physiologisch wirksamen substanzen.

Info

Publication number
ATE100150T1
ATE100150T1 AT87113185T AT87113185T ATE100150T1 AT E100150 T1 ATE100150 T1 AT E100150T1 AT 87113185 T AT87113185 T AT 87113185T AT 87113185 T AT87113185 T AT 87113185T AT E100150 T1 ATE100150 T1 AT E100150T1
Authority
AT
Austria
Prior art keywords
physiologically active
procedure
active substances
determining
determining physiologically
Prior art date
Application number
AT87113185T
Other languages
English (en)
Inventor
Yoshio Toyomaki
Katsumi Nishikawa
Hitoshi Kawakubo
Original Assignee
Nippon Zoki Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=16664398&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE100150(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Nippon Zoki Pharmaceutical Co filed Critical Nippon Zoki Pharmaceutical Co
Application granted granted Critical
Publication of ATE100150T1 publication Critical patent/ATE100150T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/56—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2337/00—N-linked chromogens for determinations of peptidases and proteinases
    • C12Q2337/20—Coumarin derivatives
    • C12Q2337/22—7-Amino-4-methylcoumarin, i.e. AMC, MCA
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
    • G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
    • G01N2333/96425—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
    • G01N2333/96427—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
    • G01N2333/9643—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
    • G01N2333/96433—Serine endopeptidases (3.4.21)
    • G01N2333/96441—Serine endopeptidases (3.4.21) with definite EC number
    • G01N2333/96455—Kallikrein (3.4.21.34; 3.4.21.35)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
    • G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
    • G01N2333/96425—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
    • G01N2333/96427—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
    • G01N2333/9643—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
    • G01N2333/96433—Serine endopeptidases (3.4.21)
    • G01N2333/96441—Serine endopeptidases (3.4.21) with definite EC number
    • G01N2333/96458—Factor XII (3.4.21.38)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
    • G01N2400/10—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • G01N2400/38—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence, e.g. gluco- or galactomannans, Konjac gum, Locust bean gum or Guar gum
    • G01N2400/40—Glycosaminoglycans, i.e. GAG or mucopolysaccharides, e.g. chondroitin sulfate, dermatan sulfate, hyaluronic acid, heparin, heparan sulfate, and related sulfated polysaccharides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Genetics & Genomics (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT87113185T 1986-09-10 1987-09-09 Verfahren zur bestimmung von physiologisch wirksamen substanzen. ATE100150T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP21495986 1986-09-10
EP87113185A EP0259857B1 (de) 1986-09-10 1987-09-09 Verfahren zur Bestimmung von physiologisch wirksamen Substanzen

Publications (1)

Publication Number Publication Date
ATE100150T1 true ATE100150T1 (de) 1994-01-15

Family

ID=16664398

Family Applications (1)

Application Number Title Priority Date Filing Date
AT87113185T ATE100150T1 (de) 1986-09-10 1987-09-09 Verfahren zur bestimmung von physiologisch wirksamen substanzen.

Country Status (7)

Country Link
US (1) US4985354A (de)
EP (1) EP0259857B1 (de)
JP (1) JPS63185398A (de)
KR (1) KR960009766B1 (de)
AT (1) ATE100150T1 (de)
DE (1) DE3788762T2 (de)
ES (1) ES2061459T3 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE140034T1 (de) * 1990-04-17 1996-07-15 Analytical Control Syst Inc Koagulationsassays und reagenzien
WO1994019690A1 (en) * 1993-02-17 1994-09-01 Cardiovascular Diagnostics, Inc. Dry chemistry cascade immunoassay and affinity assay
JP2588109B2 (ja) * 1993-03-19 1997-03-05 日本臓器製薬株式会社 鎮痛剤
JP3213831B2 (ja) * 1993-08-06 2001-10-02 日本臓器製薬株式会社 被検物質の活性測定方法
JP3213832B2 (ja) * 1993-08-06 2001-10-02 日本臓器製薬株式会社 被検物質の活性測定法
JP2594222B2 (ja) * 1993-09-28 1997-03-26 日本臓器製薬株式会社 新規生理活性物質−ｋｆ
SE9601901D0 (sv) 1996-05-20 1996-05-20 Lars Bjoerck Quinine antagonists for use as a pharmaceutical
JPH1084995A (ja) * 1996-09-12 1998-04-07 Nippon Zoki Pharmaceut Co Ltd 血液凝固第ｘｉｉ因子活性化法
JP4033936B2 (ja) * 1997-01-08 2008-01-16 日本臓器製薬株式会社 一酸化窒素産生抑制剤
US6242210B1 (en) * 1997-05-20 2001-06-05 Actinova Limited Treatment of bacterial infections
JPH1180005A (ja) * 1997-09-12 1999-03-23 Nippon Zoki Pharmaceut Co Ltd 骨粗鬆症治療剤
KR19990044835A (ko) 1997-11-28 1999-06-25 고니시 진우에몬 생약추출물
KR20010020741A (ko) 1999-04-15 2001-03-15 고니시 진우에몬 신규의 생체 활성화 물질
KR20010082721A (ko) 2000-02-18 2001-08-30 고니시 진우에몬 지방산 함유 조성물
US6913900B2 (en) 2001-08-29 2005-07-05 Nippon Zoki Pharmaceutical Co., Ltd. Plasma prekallikrein activation and kallikrein production assay
EP1573339A2 (de) * 2002-12-20 2005-09-14 Axis-Shield Diagnostics Limited Nachweis oder bestimmung von faktor xii varianten
KR101307999B1 (ko) * 2004-12-01 2013-09-12 니폰 조키 세야쿠 가부시키가이샤 건조물 및 그 제조방법
US20060134646A1 (en) * 2004-12-17 2006-06-22 Ansari Aftab A Method for treatment of HIV infection
IL273688B2 (en) 2013-01-20 2024-12-01 Dyax Corp Evaluation and treatment of bradykinin-mediated disorders
WO2015061182A1 (en) 2013-10-21 2015-04-30 Dyax Corp. Diagnosis and treatment of autoimmune diseases
EP3060582B1 (de) * 2013-10-21 2020-09-23 Dyax Corp. Assays zur bestimmung von plasmakallikreinsystem-biomarkern
EP3839514B1 (de) 2015-10-19 2023-12-13 Takeda Pharmaceutical Company Limited Immunoassay zum nachweis von gespaltenem hochmolekularem kininogen
CN111057745B (zh) * 2019-12-30 2022-08-12 中国科学院生态环境研究中心 一种物质的血液毒性效应的高通量筛选方法
WO2025054675A1 (en) * 2023-09-16 2025-03-20 Haematex Research Pty Limited Methods and compositions for deactivating a blood coagulation interfering compound

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4335203A (en) * 1980-07-10 1982-06-15 The Regents Of The University Of California Method for identifying potential contrast media reactors

Also Published As

Publication number Publication date
JPS63185398A (ja) 1988-07-30
DE3788762D1 (de) 1994-02-24
KR880004314A (ko) 1988-06-07
EP0259857B1 (de) 1994-01-12
KR960009766B1 (ko) 1996-07-24
DE3788762T2 (de) 1994-06-23
JPH0414000B2 (de) 1992-03-11
EP0259857A2 (de) 1988-03-16
ES2061459T3 (es) 1994-12-16
US4985354A (en) 1991-01-15
EP0259857A3 (en) 1990-03-07

Similar Documents

Publication Publication Date Title
ATE100150T1 (de) Verfahren zur bestimmung von physiologisch wirksamen substanzen.
DE69110098D1 (de) Teststreifen zur visuellen Bestimmung der Blutglucosekonzentration.
DE69022786D1 (de) Verfahren zur Bestimmung der Konzentration von Glucose.
ATE210826T1 (de) Verfahren zur bestimmung von cyclooxygenase-1- aktivität
DE59710488D1 (de) Vorrichtung und Verwendung einer Vorrichtung zur Bestimmung der Konzentration von Hämoglobinderivaten in einer unverdünnten, unhämolysierten Vollblutprobe
DE3887694D1 (de) Vorrichtung zur bestimmung der koagulationszeit einer blutprobe.
ATA32179A (de) Verfahren und reagens zur bestimmung der gerinnungsverhindernden aktivitaet im plasma
ATE97791T1 (de) Vorrichtung zur bestimmung der konzentration von zumindest einer in organischem gewebe vorliegenden substanz.
DE59208032D1 (de) Funktioneller Test und Reagenz zur Bestimmung von Fibrinogen
FI881704A7 (fi) Menetelmä ja laite analyyttitason määrittämiseksi kokoverinäytteestä.
ATE181599T1 (de) Methode zur bestimmung von hämoglobinaddukten
DE3870405D1 (de) Testvorrichtung zur bestimmung von okkultem blut und glukose.
ATE17262T1 (de) Verfahren zur quantitativen bestimmung von blutgerinnungsfaktor xii in humanplasma.
DE68917324D1 (de) Methode zur Immobilisierung von physiologisch aktiven Substanzen.
NO953770L (no) Analysemetode
DE3650147D1 (de) Verfahren zur bestimmung menschlicher lungenoberflächenaktiver substanz und reagenziensatz dazu.
DE3765745D1 (de) Verfahren zur bestimmung der molekular-diffusionsparameter und/oder der durchblutung von lebendem gewebe.
DE3776525D1 (de) Immunochemisches verfahren zur bestimmung von stabilem glykosiliertem haemoglobin.
ATA18686A (de) Verfahren zur bestimmung der konzentration von in einer substanz enthaltenen stoffen, insbesondere von sauerstoff
FI895215A7 (fi) Menetelmä antitrombiini III:n biologisen aktiivisuuden määrittämiseksi ja reagenssi sitä varten
DE69014201D1 (de) Verfahren und testsatz zur bestimmung von tyrosinphosphorylierungs- und dephosphorylierungsaktivitäten.
DE68909995D1 (de) Reagenz zur Bestimmung von Kreatinkinase und Messverfahren dafür.
DE3889279D1 (de) Diagnostisches Mittel und Verfahren zur Bestimmung von Apolipoprotein B.
KR880701885A (ko) 2개의 표식물을 이용한 분석물질의 농도 검정 방법 및 기기
DK173884A (da) Fremgangsmaade til kvantitativ bestemmelse af haemoglobinkoncentrationen i en biologisk proeve

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee