ATE101610T1 - Indol-derivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische praeparate. - Google Patents

Indol-derivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische praeparate.

Info

Publication number: ATE101610T1
Authority: AT; Austria
Prior art keywords: lower alkyl; linear; denotes; hydrogen atom; alkyl group
Prior art date: 1988-12-06

Application number

AT89403356T

Other languages

English (en)

Inventor

Charles Malen

Jean-Michel Lacoste

Michel Laubie

Original Assignee

Adir

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-12-06

Filing date

1989-12-05

Publication date

1994-03-15

1989-12-05 Application filed by Adir filed Critical Adir

1994-03-15 Application granted granted Critical

1994-03-15 Publication of ATE101610T1 publication Critical patent/ATE101610T1/de

Links

SIKJAQJRHWYJAI-UHFFFAOYSA-N Indole Chemical class C1=CC=C2NC=CC2=C1 SIKJAQJRHWYJAI-UHFFFAOYSA-N 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1
238000000034 method Methods 0.000 title 1
239000000825 pharmaceutical preparation Substances 0.000 title 1
125000000217 alkyl group Chemical group 0.000 abstract 11
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 7
125000003545 alkoxy group Chemical group 0.000 abstract 3
125000003118 aryl group Chemical group 0.000 abstract 3
125000005843 halogen group Chemical group 0.000 abstract 3
IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
229910052757 nitrogen Inorganic materials 0.000 abstract 2
NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
125000005842 heteroatom Chemical group 0.000 abstract 1
229940126601 medicinal product Drugs 0.000 abstract 1
125000002950 monocyclic group Chemical group 0.000 abstract 1
125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
229910052760 oxygen Inorganic materials 0.000 abstract 1
239000001301 oxygen Substances 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
229920006395 saturated elastomer Polymers 0.000 abstract 1
229910052717 sulfur Inorganic materials 0.000 abstract 1
239000011593 sulfur Substances 0.000 abstract 1
125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Hospice & Palliative Care (AREA)
Anesthesiology (AREA)
Otolaryngology (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Indole Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)

AT89403356T 1988-12-06 1989-12-05 Indol-derivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische praeparate. ATE101610T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR8815937A FR2639944B1 (fr)	1988-12-06	1988-12-06	Nouveaux derives de l'indole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
EP89403356A EP0373061B1 (de)	1988-12-06	1989-12-05	Indol-Derivate, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Präparate

Publications (1)

Publication Number	Publication Date
ATE101610T1 true ATE101610T1 (de)	1994-03-15

Family

ID=9372595

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT89403356T ATE101610T1 (de)	1988-12-06	1989-12-05	Indol-derivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische praeparate.

Country Status (15)

Country	Link
US (1)	US5030646A (de)
EP (1)	EP0373061B1 (de)
JP (1)	JPH064637B2 (de)
AT (1)	ATE101610T1 (de)
AU (1)	AU618648B2 (de)
CA (1)	CA2004643A1 (de)
DE (1)	DE68913167T2 (de)
DK (1)	DK614989A (de)
ES (1)	ES2063157T3 (de)
FR (1)	FR2639944B1 (de)
IE (1)	IE64209B1 (de)
NZ (1)	NZ231634A (de)
OA (1)	OA09147A (de)
PT (1)	PT92494B (de)
ZA (1)	ZA899321B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8928837D0 (en) *	1989-12-21	1990-02-28	Beecham Group Plc	Pharmaceuticals
HU211081B (en) *	1990-12-18	1995-10-30	Sandoz Ag	Process for producing indole derivatives as serotonin antagonists and pharmaceutical compositions containing the same
US5776962A (en) *	1994-08-03	1998-07-07	Cell Pathways, Inc.	Lactone compounds for treating patient with precancerous lesions
US5696159A (en) *	1994-08-03	1997-12-09	Cell Pathways, Inc.	Lactone compounds for treating patients with precancerous lesions
CN109438448B (zh) *	2018-11-07	2021-08-27	成都大学	一种吲哚并七元环化合物及其制备方法和用途

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3971806A (en) *	1974-05-09	1976-07-27	Warner-Lambert Company	Indolothiopyrones
JPS557201A (en) *	1978-05-23	1980-01-19	Shionogi & Co Ltd	Derivative of tetrahydrothiopyrano(2,3-b)indole
JPS56120686A (en) *	1980-02-27	1981-09-22	Shionogi & Co Ltd	Tetrahydrothiopyrano 3,2-b indole derivative
SE460359B (sv) *	1984-01-25	1989-10-02	Glaxo Group Ltd	3-imidazolylmetyltetrahydrokarbazoloner, foerfarande foer framstaellning av dessa och en farmaceutisk komposition
JPH02131485A (ja) *	1988-11-10	1990-05-21	Yamanouchi Pharmaceut Co Ltd	３−置換テトラヒドロチオピラノ〔２，３−ｂ〕インドール誘導体及びその中間体

1988
- 1988-12-06 FR FR8815937A patent/FR2639944B1/fr not_active Expired - Lifetime
1989
- 1989-12-05 ES ES89403356T patent/ES2063157T3/es not_active Expired - Lifetime
- 1989-12-05 PT PT92494A patent/PT92494B/pt not_active IP Right Cessation
- 1989-12-05 NZ NZ231634A patent/NZ231634A/en unknown
- 1989-12-05 EP EP89403356A patent/EP0373061B1/de not_active Expired - Lifetime
- 1989-12-05 US US07/446,034 patent/US5030646A/en not_active Expired - Fee Related
- 1989-12-05 CA CA002004643A patent/CA2004643A1/fr not_active Abandoned
- 1989-12-05 DE DE68913167T patent/DE68913167T2/de not_active Expired - Fee Related
- 1989-12-05 AT AT89403356T patent/ATE101610T1/de not_active IP Right Cessation
- 1989-12-05 AU AU45834/89A patent/AU618648B2/en not_active Ceased
- 1989-12-05 IE IE387189A patent/IE64209B1/en not_active IP Right Cessation
- 1989-12-06 OA OA59690A patent/OA09147A/xx unknown
- 1989-12-06 ZA ZA899321A patent/ZA899321B/xx unknown
- 1989-12-06 DK DK614989A patent/DK614989A/da not_active Application Discontinuation
- 1989-12-06 JP JP1315531A patent/JPH064637B2/ja not_active Expired - Lifetime

Also Published As

Publication number	Publication date
DE68913167D1 (de)	1994-03-24
DK614989D0 (da)	1989-12-06
JPH064637B2 (ja)	1994-01-19
AU4583489A (en)	1990-06-14
FR2639944B1 (fr)	1991-01-18
FR2639944A1 (fr)	1990-06-08
PT92494A (pt)	1990-06-29
JPH02200685A (ja)	1990-08-08
DE68913167T2 (de)	1994-09-01
IE893871L (en)	1990-06-06
ZA899321B (en)	1990-08-29
OA09147A (fr)	1991-10-31
ES2063157T3 (es)	1995-01-01
NZ231634A (en)	1991-06-25
IE64209B1 (en)	1995-07-26
EP0373061B1 (de)	1994-02-16
DK614989A (da)	1990-06-07
AU618648B2 (en)	1992-01-02
US5030646A (en)	1991-07-09
EP0373061A1 (de)	1990-06-13
PT92494B (pt)	1995-08-09
CA2004643A1 (fr)	1990-06-06

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Legal Events

Date	Code	Title	Description
1994-11-15	UEP	Publication of translation of european patent specification
1997-09-15	REN	Ceased due to non-payment of the annual fee