ATE101611T1 - Cephalosporine, mit an der stelle 3 einem substituierten vinylradikal, verfahren zu ihrer herstellung, ihre anwendung als medikamente, ihre sie enthaltenden praeparate und zwischenverbindungen. - Google Patents

Cephalosporine, mit an der stelle 3 einem substituierten vinylradikal, verfahren zu ihrer herstellung, ihre anwendung als medikamente, ihre sie enthaltenden praeparate und zwischenverbindungen.

Info

Publication number: ATE101611T1
Authority: AT; Austria
Prior art keywords: medications; cephalosporins; processes; production; intermediate compounds
Prior art date: 1987-11-03

Application number

AT88402740T

Other languages

English (en)

Inventor

Joszef Aszodi

Alain Bonnet

Jean-Francois Chantot

Original Assignee

Roussel Uclaf

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-11-03

Filing date

1988-11-02

Publication date

1994-03-15

1988-11-02 Application filed by Roussel Uclaf filed Critical Roussel Uclaf

1994-03-15 Application granted granted Critical

1994-03-15 Publication of ATE101611T1 publication Critical patent/ATE101611T1/de

Links

229940079593 drug Drugs 0.000 title abstract 2
239000003814 drug Substances 0.000 title abstract 2
238000000034 method Methods 0.000 title abstract 2
238000002360 preparation method Methods 0.000 title abstract 2
229930186147 Cephalosporin Natural products 0.000 title 1
229940124587 cephalosporin Drugs 0.000 title 1
HOKIDJSKDBPKTQ-GLXFQSAKSA-N cephalosporin C Chemical compound S1CC(COC(=O)C)=C(C(O)=O)N2C(=O)[C@@H](NC(=O)CCC[C@@H](N)C(O)=O)[C@@H]12 HOKIDJSKDBPKTQ-GLXFQSAKSA-N 0.000 title 1
150000001875 compounds Chemical class 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1
ORGHESHFQPYLAO-UHFFFAOYSA-N vinyl radical Chemical group C=[CH] ORGHESHFQPYLAO-UHFFFAOYSA-N 0.000 title 1
FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 abstract 1
229910052783 alkali metal Inorganic materials 0.000 abstract 1
150000001340 alkali metals Chemical class 0.000 abstract 1
229910052784 alkaline earth metal Inorganic materials 0.000 abstract 1
150000001342 alkaline earth metals Chemical class 0.000 abstract 1
125000003342 alkenyl group Chemical group 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
125000000304 alkynyl group Chemical group 0.000 abstract 1
125000000753 cycloalkyl group Chemical group 0.000 abstract 1
239000000543 intermediate Substances 0.000 abstract 1
229910052749 magnesium Inorganic materials 0.000 abstract 1
239000011777 magnesium Substances 0.000 abstract 1
238000002483 medication Methods 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
150000007530 organic bases Chemical class 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Communicable Diseases (AREA)
Pharmacology & Pharmacy (AREA)
Oncology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Cephalosporin Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

AT88402740T 1987-11-03 1988-11-02 Cephalosporine, mit an der stelle 3 einem substituierten vinylradikal, verfahren zu ihrer herstellung, ihre anwendung als medikamente, ihre sie enthaltenden praeparate und zwischenverbindungen. ATE101611T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR8715210A FR2622585B1 (fr)	1987-11-03	1987-11-03	Nouvelles cephalosporines comportant en position 3 un radical vinyle substitue, leur procede de preparation, leur application comme medicaments, les compositions les renfermant et les nouveaux intermediaires obtenus
EP88402740A EP0315518B1 (de)	1987-11-03	1988-11-02	Cephalosporine, mit an der Stelle 3 einem substituierten Vinylradikal, Verfahren zu ihrer Herstellung, ihre Anwendung als Medikamente, ihre sie enthaltenden Präparate und Zwischenverbindungen

Publications (1)

Publication Number	Publication Date
ATE101611T1 true ATE101611T1 (de)	1994-03-15

Family

ID=9356422

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT88402740T ATE101611T1 (de)	1987-11-03	1988-11-02	Cephalosporine, mit an der stelle 3 einem substituierten vinylradikal, verfahren zu ihrer herstellung, ihre anwendung als medikamente, ihre sie enthaltenden praeparate und zwischenverbindungen.

Country Status (8)

Country	Link
US (1)	US5075298A (de)
EP (1)	EP0315518B1 (de)
JP (1)	JP2717820B2 (de)
AT (1)	ATE101611T1 (de)
CA (1)	CA1313654C (de)
DE (1)	DE3887824T2 (de)
ES (1)	ES2061709T3 (de)
FR (1)	FR2622585B1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2684995A1 (en) *	1991-12-12	1993-06-18	Roussel Uclaf	Cephalosporins containing a ( alpha -carboxy-3,4-dihydroxybenzyloxyimino) group, preparation process and intermediates, application as medicaments and pharmaceutical compositions
FR2663332B1 (fr) *	1990-06-15	1997-11-07	Roussel Uclaf	Nouvelles cephalosporines comportant en position 3 un radical propenyle substitue par un ammonium quaternaire, leur procede de preparation, leur application comme medicaments, les compositions les renfermant et les nouveaux intermediaires obtenus.
US5373001A (en) *	1990-06-15	1994-12-13	Roussel Uclaf	Cephalosporins
US5397779A (en) *	1990-06-15	1995-03-14	Roussel-Uclaf	Cephalosporins
US5143911A (en) *	1990-08-23	1992-09-01	Bristol-Myers Squibb Company	Antibiotic c-3 di-hydroxyphenyl substituted cephalosporin compounds, compositions and method of use thereof
US5126336A (en) *	1990-08-23	1992-06-30	Bristol-Myers Squibb Company	Antibiotic c-3 catechol-substituted cephalosporin compounds, compositions and method of use thereof
US5234920A (en) *	1990-08-23	1993-08-10	Bristol-Myers Squibb Company	Antibiotic C-7 catechol-substituted cephalosporin compounds, compositions, and method of use thereof
FR2678273B1 (fr) *	1991-06-25	1995-03-03	Roussel Uclaf	Nouvelles cephalosporines comportant un noyau 2-thia cepheme, leur procede de preparation, leur application comme medicaments, et les nouveaux intermediaires obtenus.
AT396108B (de) *	1991-08-21	1993-06-25	Biochemie Gmbh	Neues verfahren und neue zwischenprodukte zur herstellung von 7-aminocephalosporansaeurederivaten
FR2696180B1 (fr) *	1992-09-28	1994-10-28	Roussel Uclaf	Nouvelles céphalosporines comportant en position 7, un radical benzyloxyimino substitué, leur procédé de préparation et leur application comme médicaments.
MX9207198A (es) *	1991-12-12	1993-07-01	Roussel Uclaf	Nuevas cefalosporinas, procedimiento para su preparacion y composiciones farmaceuticas que las contienen
FR2684994B1 (fr) *	1991-12-12	1995-03-03	Roussel Uclaf	Nouvelles cephalosporines comportant en position 7, un radical benzyloxyimino substitue, leur procede de preparation et leur application comme medicaments.
FR2699177A1 (fr) *	1992-12-11	1994-06-17	Roussel Uclaf	Nouvelles céphalosporines comportant en position 7 un radical oxyimino substitué, leur procédé et intermédiaires de préparation et leur application comme médicaments.
EP0628562A1 (de) *	1993-06-10	1994-12-14	Roussel Uclaf	Cephalospornic mit einem, in Position 7 substituiertem Oximino-Radikal, Zwischenverbindungen, Verfahren zu ihrer Herstellung und ihre Anwendung als Medikamente
JPH0741484A (ja) *	1993-07-29	1995-02-10	Katayama Seiyakushiyo:Kk	セフェム化合物及び抗菌剤
KR100248851B1 (ko) *	1994-08-16	2000-04-01	이치로 키타사토	신규 세펨 유도체
US7427680B2 (en) *	2001-01-12	2008-09-23	The Regents Of The University Of California	Fluorogenic substrates for BETA-lactamase gene expression
AU761450B2 (en)	1998-06-22	2003-06-05	Basilea Pharmaceutica Ag	Propenyl cephalosporin derivatives
WO2005071096A2 (en)	2004-01-21	2005-08-04	Molecular Probes, Inc.	Derivatives of cephalosporin and clavulanic acid for detecting beta-lacamase in a sample

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4486586A (en) *	1983-02-10	1984-12-04	Bristol-Myers Company	Cephalosporin derivatives
CA1276929C (en) *	1984-04-09	1990-11-27	Masahisa Oka	Cephalosporin antibacterial agents
US4708955A (en) *	1985-06-24	1987-11-24	Bristol-Myers Company	3-(substituted)propenyl-7-aminothiazol-ylcephalosporanic acids and esters thereof

1987
- 1987-11-03 FR FR8715210A patent/FR2622585B1/fr not_active Expired - Fee Related
1988
- 1988-10-31 US US07/265,252 patent/US5075298A/en not_active Expired - Fee Related
- 1988-11-02 ES ES88402740T patent/ES2061709T3/es not_active Expired - Lifetime
- 1988-11-02 DE DE3887824T patent/DE3887824T2/de not_active Expired - Fee Related
- 1988-11-02 EP EP88402740A patent/EP0315518B1/de not_active Expired - Lifetime
- 1988-11-02 AT AT88402740T patent/ATE101611T1/de not_active IP Right Cessation
- 1988-11-02 CA CA000581927A patent/CA1313654C/fr not_active Expired - Fee Related
- 1988-11-04 JP JP63277542A patent/JP2717820B2/ja not_active Expired - Lifetime

Also Published As

Publication number	Publication date
JPH01151586A (ja)	1989-06-14
DE3887824T2 (de)	1994-06-16
US5075298A (en)	1991-12-24
ES2061709T3 (es)	1994-12-16
FR2622585A1 (fr)	1989-05-05
FR2622585B1 (fr)	1991-04-19
EP0315518B1 (de)	1994-02-16
DE3887824D1 (de)	1994-03-24
EP0315518A1 (de)	1989-05-10
JP2717820B2 (ja)	1998-02-25
CA1313654C (fr)	1993-02-16

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Legal Events

Date	Code	Title	Description
1994-12-15	UEP	Publication of translation of european patent specification
2003-08-15	REN	Ceased due to non-payment of the annual fee