ATE1019T1 - Hyaluronidase und seine herstellung. - Google Patents

Hyaluronidase und seine herstellung.

Info

Publication number: ATE1019T1
Authority: AT; Austria
Prior art keywords: hyaluronidase; manufacture; chondroitin; hexosaminidase; endo
Prior art date: 1978-05-11

Application number

AT79101420T

Other languages

English (en)

Inventor

Keizo Yoshida

Takashi Musashiseki Mansion 604 Fujii

Hiroyuki Kikuchi

Original Assignee

Fujisawa Pharmaceutical Co. Ltd.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1978-05-11

Filing date

1979-05-10

Publication date

1982-05-15

1979-05-10 Application filed by Fujisawa Pharmaceutical Co. Ltd. filed Critical Fujisawa Pharmaceutical Co. Ltd.

1982-05-15 Application granted granted Critical

1982-05-15 Publication of ATE1019T1 publication Critical patent/ATE1019T1/de

Links

108010003272 Hyaluronate lyase Proteins 0.000 title abstract 2
102000001974 Hyaluronidases Human genes 0.000 title abstract 2
229960002773 hyaluronidase Drugs 0.000 title abstract 2
238000004519 manufacturing process Methods 0.000 title 1
KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 abstract 1
SQDAZGGFXASXDW-UHFFFAOYSA-N 5-bromo-2-(trifluoromethoxy)pyridine Chemical compound FC(F)(F)OC1=CC=C(Br)C=N1 SQDAZGGFXASXDW-UHFFFAOYSA-N 0.000 abstract 1
229920002567 Chondroitin Polymers 0.000 abstract 1
229920001287 Chondroitin sulfate Polymers 0.000 abstract 1
241001052688 Streptomyces koganeiensis Species 0.000 abstract 1
DLGJWSVWTWEWBJ-HGGSSLSASA-N chondroitin Chemical compound CC(O)=N[C@@H]1[C@H](O)O[C@H](CO)[C@H](O)[C@@H]1OC1[C@H](O)[C@H](O)C=C(C(O)=O)O1 DLGJWSVWTWEWBJ-HGGSSLSASA-N 0.000 abstract 1
229940059329 chondroitin sulfate Drugs 0.000 abstract 1
229920002674 hyaluronan Polymers 0.000 abstract 1
229960003160 hyaluronic acid Drugs 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C12N9/2405—Glucanases
- C12N9/2408—Glucanases acting on alpha -1,4-glucosidic bonds
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/886—Streptomyces

Landscapes

Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Organic Chemistry (AREA)
Zoology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Wood Science & Technology (AREA)
Microbiology (AREA)
Biotechnology (AREA)
Biomedical Technology (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
General Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Enzymes And Modification Thereof (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

AT79101420T 1978-05-11 1979-05-10 Hyaluronidase und seine herstellung. ATE1019T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP53056313A JPS6033474B2 (ja)	1978-05-11	1978-05-11	新規なヒアルロニダ−ゼｂｍｐ−８２３１およびその製造法
EP79101420A EP0005751B1 (de)	1978-05-11	1979-05-10	Hyaluronidase und seine Herstellung

Publications (1)

Publication Number	Publication Date
ATE1019T1 true ATE1019T1 (de)	1982-05-15

Family

ID=13023655

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT79101420T ATE1019T1 (de)	1978-05-11	1979-05-10	Hyaluronidase und seine herstellung.

Country Status (5)

Country	Link
US (1)	US4258134A (de)
EP (1)	EP0005751B1 (de)
JP (1)	JPS6033474B2 (de)
AT (1)	ATE1019T1 (de)
DE (1)	DE2962780D1 (de)

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US4801475A (en) *	1984-08-23	1989-01-31	Gregory Halpern	Method of hydrophilic coating of plastics
GB8504025D0 (en) *	1985-02-16	1985-03-20	Biopharm Ltd	Hyaluronidase
SE456245B (sv) *	1986-07-09	1988-09-19	Pharmacia Ab	Enzympreparation innehallande krillhyaluronidas
JP2699078B2 (ja) *	1987-12-23	1998-01-19	北里研究所（社団法人）	ムシン分解酵素及びその製造法
US6610292B2 (en)	1995-11-22	2003-08-26	Ista Pharmaceuticals, Inc.	Use of hyaluronidase in the manufacture of an ophthalmic preparation for liquefying vitreous humor in the treatment of eye disorders
US5866120A (en) *	1995-11-22	1999-02-02	Advanced Corneal Systems, Inc.	Method for accelerating clearance of hemorrhagic blood from the vitreous humor with hyaluronidase
CN1200698C (zh) *	1998-03-09	2005-05-11	伊斯塔药品公司	角膜硬化剂在制备治疗眼睛屈光不正的药物中的用途
EP1074631B1 (de)	1998-04-30	2005-08-24	Maruha Corporation	Verbindungen, deren struktur derivate von glukuronsäure und glukosamin enthält, verfahren zu deren herstellung und deren verwendung
RU2174557C1 (ru) *	2000-11-22	2001-10-10	Предприятие по производству бакпрепаратов научно-исследовательского института эпидемиологии и микробиологии им. Н.Ф. Гамалеи РАМН	Способ получения гиалуронидазы стрептококковой
AU2004218354B2 (en) *	2003-03-05	2009-10-01	Halozyme, Inc.	Soluble hyaluronidase glycoprotein (sHASEGP), process for preparing the same, uses and pharmaceutical compositions comprising thereof
MXPA03011987A (es)	2003-12-19	2005-06-23	Osio Sancho Alberto	Metodo para el tratamiento de la presbicia induciendo cambios en el poder y fisiologia corneal.
PL2229407T3 (pl)	2008-01-09	2017-06-30	Sanofi-Aventis Deutschland Gmbh	Nowe pochodne insuliny o ekstremalnie spowolnionym profilu czasu działania
EP3228320B1 (de)	2008-10-17	2019-12-18	Sanofi-Aventis Deutschland GmbH	Kombination von einem insulin und einem glp-1-agonisten
US20120219554A2 (en) *	2009-05-14	2012-08-30	Fidia Farmaceutici S.P.A.	Extracellular yaluronidase from streptomyces koganeiensis
EP3202394A1 (de) *	2009-07-06	2017-08-09	Sanofi-Aventis Deutschland GmbH	Wässrige insulinzubereitungen enthaltend methionin
PE20121316A1 (es)	2009-11-13	2012-10-05	Sanofi Aventis Deutschland	Composicion farmaceutica que comprende un agonista de glp-1 y metionina
PT2554183T (pt)	2009-11-13	2018-07-09	Sanofi Aventis Deutschland	Composição farmacêutica que compreende um agonista de glp-1, uma insulina e metionina
CZ2009836A3 (cs)	2009-12-11	2011-06-22	Contipro C A.S.	Derivát kyseliny hyaluronové oxidovaný v poloze 6 glukosaminové cásti polysacharidu selektivne na aldehyd, zpusob jeho prípravy a zpusob jeho modifikace
CZ302503B6 (cs)	2009-12-11	2011-06-22	Contipro C A.S.	Zpusob prípravy derivátu kyseliny hyaluronové oxidovaného v poloze 6 glukosaminové cásti polysacharidu selektivne na aldehyd a zpusob jeho modifikace
US20140148384A1 (en)	2010-08-30	2014-05-29	Sanofi-Aventis Deutschland Gmbh	Use of ave0010 for the manufacture of a medicament for the treatment of diabetes mellitus type 2
US9821032B2 (en)	2011-05-13	2017-11-21	Sanofi-Aventis Deutschland Gmbh	Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin
CN108079281A (zh)	2011-08-29	2018-05-29	赛诺菲-安万特德国有限公司	用于2型糖尿病患者中的血糖控制的药物组合
TWI559929B (en)	2011-09-01	2016-12-01	Sanofi Aventis Deutschland	Pharmaceutical composition for use in the treatment of a neurodegenerative disease
CZ2012136A3 (cs)	2012-02-28	2013-06-05	Contipro Biotech S.R.O.	Deriváty na bázi kyseliny hyaluronové schopné tvorit hydrogely, zpusob jejich prípravy, hydrogely na bázi techto derivátu, zpusob jejich prípravy a pouzití
US20150210753A1 (en)	2012-07-26	2015-07-30	Momenta Pharmaceuticals, Inc.	Glycoproteins with anti-inflammatory properties
CZ304512B6 (cs)	2012-08-08	2014-06-11	Contipro Biotech S.R.O.	Derivát kyseliny hyaluronové, způsob jeho přípravy, způsob jeho modifikace a použití
CN104823100B (zh)	2012-08-10	2020-04-24	奥西奥公司以约利亚健康公司名义经营	隐形眼镜和为个体的眼睛测定隐形眼镜的适配的方法
CZ304140B6 (cs)	2012-09-27	2013-11-13	Contipro Biotech S.R.O.	Enzym hyaluronan-lyáza, zpusob jeho výroby, pouzití a zpusob prípravy nízkomolekulárního hyaluronanu
CZ2012842A3 (cs)	2012-11-27	2014-08-20	Contipro Biotech S.R.O.	Nanomicelární kompozice na bázi C6-C18-acylovaného hyaluronanu, způsob přípravy C6-C18-acylovaného hyaluronanu, způsob přípravy nanomicelární kompozice a stabilizované nanomicelární kompozice a použití
TWI641381B (zh)	2013-02-04	2018-11-21	法商賽諾菲公司	胰島素類似物及／或胰島素衍生物之穩定化醫藥調配物
ES2708759T3 (es)	2013-05-13	2019-04-11	Momenta Pharmaceuticals Inc	Procedimientos para el tratamiento de la neurodegeneración
ITMI20130992A1 (it)	2013-06-17	2014-12-18	Fidia Farmaceutici	Ialuronidasi batterica e metodo per la sua produzione
WO2015057622A1 (en)	2013-10-16	2015-04-23	Momenta Pharmaceuticals, Inc.	Sialylated glycoproteins
KR20160104724A (ko)	2014-01-09	2016-09-05	사노피	인슐린 유사체 및/또는 인슐린 유도체의 안정화된 약제학적 제형
RU2016132340A (ru)	2014-01-09	2018-02-14	Санофи	Стабилизированные фармацевтические составы на основе инсулина аспарта
CN105899191B (zh)	2014-01-09	2020-06-16	赛诺菲	胰岛素类似物和/或胰岛素衍生物的稳定化不含甘油的药物制剂
CZ2014150A3 (cs)	2014-03-11	2015-05-20	Contipro Biotech S.R.O.	Konjugáty oligomeru kyseliny hyaluronové nebo její soli, způsob jejich přípravy a použití
CZ2014451A3 (cs)	2014-06-30	2016-01-13	Contipro Pharma A.S.	Protinádorová kompozice na bázi kyseliny hyaluronové a anorganických nanočástic, způsob její přípravy a použití
TWI758239B (zh)	2014-12-12	2022-03-21	德商賽諾菲阿凡提斯德意志有限公司	甘精胰島素/利司那肽固定比率配製劑
CZ309295B6 (cs)	2015-03-09	2022-08-10	Contipro A.S.	Samonosný, biodegradabilní film na bázi hydrofobizované kyseliny hyaluronové, způsob jeho přípravy a použití
TWI748945B (zh)	2015-03-13	2021-12-11	德商賽諾菲阿凡提斯德意志有限公司	第２型糖尿病病患治療
TW201705975A (zh)	2015-03-18	2017-02-16	賽諾菲阿凡提斯德意志有限公司	第２型糖尿病病患之治療
CZ2015398A3 (cs)	2015-06-15	2017-02-08	Contipro A.S.	Způsob síťování polysacharidů s využitím fotolabilních chránicích skupin
CZ306662B6 (cs)	2015-06-26	2017-04-26	Contipro A.S.	Deriváty sulfatovaných polysacharidů, způsob jejich přípravy, způsob jejich modifikace a použití
CZ308106B6 (cs)	2016-06-27	2020-01-08	Contipro A.S.	Nenasycené deriváty polysacharidů, způsob jejich přípravy a jejich použití

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE1946682A1 (de)	1968-09-21	1971-01-28	Amano Pharma Co Ltd	Verfahren zur Herstellung von Hyaluronidase
US3728223A (en) *	1971-10-08	1973-04-17	Amano Pharma Co Ltd	Production of hyaluronidase from a strain of streptomyces
JPS5413510B2 (de) *	1973-08-28	1979-05-31
SU513075A1 (ru) *	1974-09-09	1976-05-05	Московский технологический институт пищевой промышленности	Способ получени гиалуронидазы

1978
- 1978-05-11 JP JP53056313A patent/JPS6033474B2/ja not_active Expired
1979
- 1979-05-03 US US06/035,719 patent/US4258134A/en not_active Expired - Lifetime
- 1979-05-10 DE DE7979101420T patent/DE2962780D1/de not_active Expired
- 1979-05-10 AT AT79101420T patent/ATE1019T1/de not_active IP Right Cessation
- 1979-05-10 EP EP79101420A patent/EP0005751B1/de not_active Expired

Also Published As

Publication number	Publication date
US4258134A (en)	1981-03-24
EP0005751A1 (de)	1979-12-12
EP0005751B1 (de)	1982-05-12
JPS54147997A (en)	1979-11-19
JPS6033474B2 (ja)	1985-08-02
DE2962780D1 (en)	1982-07-01

Legal Events

Date	Code	Title	Description
1982-08-15	UEP	Publication of translation of european patent specification
1986-02-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
ATE1019T1 (de)	1982-05-15	Hyaluronidase und seine herstellung.
ATE22104T1 (de)	1986-09-15	Herstellung von pyrrolo-(3,4-c)-pyrrolen.
BE873472A (fr)	1979-05-02	Procede d'epitaxie par faisceau moleculaire avec pre-melange
NL7902254A (nl)	1979-09-25	Optisch orgaan.
GB2083459B (en)	1982-12-15	New substituted heterocyclic benzamides and their production
ATE1500T1 (de)	1982-09-15	6-chlor-2,3-dihydroxy-1,4-naphthochinon und seine 2,3-diester, und ihre herstellung.
DK240979A (da)	1980-01-07	3-azabicyclo (3,1,0) hexanderivater
NL7903010A (nl)	1979-10-22	Plantenkweeklichaam.
AR241108A2 (es)	1991-11-15	Insecticidas piretroides, acidos ciclopropancarboxilicos y esteres intermediarios y sus precedimientos de preparacion
FI790831A7 (fi)	1979-09-14	Foerfarande foer framstaellning av 1-oxo-1h-pyrimido(6,1-b)bentstiazolderivat
NO885465D0 (no)	1988-12-08	Absorpsjon av hydrogensulfid.
TR20170A (tr)	1980-09-29	Mikrobisitler olarak 1,1 difenileten tuerevleri
BE875377A (fr)	1979-07-31	Matieres plastiques ignifugees, et agents ignifuges appropries
FI793459A7 (fi)	1981-01-01	1,1,2-trifenyylialkeenijohdannaisten estereitä.
ATE132500T1 (de)	1996-01-15	24r-scymnol, herstellung und verwendung
BG28978A3 (en)	1980-08-15	Fungicide means and method for fighting the fungus
DE3782698D1 (de)	1992-12-24	5-fluoruridin-derivat und dessen herstellung.
BE875273A (fr)	1979-10-02	0-carbamoyloximes de 2,3-dihydro-4h-1-benzo-pyranne-4-ones
SU626266A1 (ru)	1978-09-30	Муфта жестка - "питега
NL185583B (nl)	1989-12-18	Luchtbehandelingskast.
SU647509A1 (ru)	1979-02-15	Вентил ционное устройство
FI792770A7 (fi)	1980-03-23	Foerfarande foer framstaellning av 1,2,3-tiadiazol-5-ylkarbamider
AU5060379A (en)	1980-04-17	Production of 5.6 dihydro-2-methyl-n-phenyl-1,4-oxathiin-3- carboxamide
JPS5517393A (en)	1980-02-06	Nncyclohexyllnnmethoxyacetoacetoamideand its use for manufacturing oomethyllnncyclohexyll 255dimethylfurann33hydroxamic acid
NL189397B (nl)	1992-11-02	Eierdoos met zichtopening.