ATE102655T1 - Extraktion von menschlichem interleukin-4 aus bakterien. - Google Patents

Extraktion von menschlichem interleukin-4 aus bakterien.

Info

Publication number
ATE102655T1
ATE102655T1 AT89304879T AT89304879T ATE102655T1 AT E102655 T1 ATE102655 T1 AT E102655T1 AT 89304879 T AT89304879 T AT 89304879T AT 89304879 T AT89304879 T AT 89304879T AT E102655 T1 ATE102655 T1 AT E102655T1
Authority
AT
Austria
Prior art keywords
human interleukin
bacteria
extraction
bacterial cells
disrupting
Prior art date
Application number
AT89304879T
Other languages
English (en)
Inventor
Yair Alroy
Paul Leibowitz
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Application granted granted Critical
Publication of ATE102655T1 publication Critical patent/ATE102655T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/5406—IL-4
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/06—Lysis of microorganisms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/82—Proteins from microorganisms
    • Y10S530/825—Bacteria

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Mycology (AREA)
  • Toxicology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT89304879T 1988-05-17 1989-05-15 Extraktion von menschlichem interleukin-4 aus bakterien. ATE102655T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/194,799 US4958007A (en) 1988-05-17 1988-05-17 Extraction of human interleukin-4- from bacteria
EP89304879A EP0342892B1 (de) 1988-05-17 1989-05-15 Extraktion von menschlichem Interleukin-4 aus Bakterien

Publications (1)

Publication Number Publication Date
ATE102655T1 true ATE102655T1 (de) 1994-03-15

Family

ID=22718949

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89304879T ATE102655T1 (de) 1988-05-17 1989-05-15 Extraktion von menschlichem interleukin-4 aus bakterien.

Country Status (11)

Country Link
US (1) US4958007A (de)
EP (2) EP0414812A1 (de)
JP (1) JPH0716434B2 (de)
AT (1) ATE102655T1 (de)
AU (1) AU632753B2 (de)
CA (1) CA1314831C (de)
DE (1) DE68913587T2 (de)
DK (1) DK273490D0 (de)
ES (1) ES2061991T3 (de)
HU (1) HU210428B (de)
WO (1) WO1989011541A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0428764B1 (de) * 1989-11-18 1994-04-20 Deutsche ITT Industries GmbH Digitaler Begrenzer zur Pegelbegrenzung eines in Digitalform vorliegenden Videosignals
US5597900A (en) * 1990-06-15 1997-01-28 Schering Corporation Crystalline interleukin-4
US5034133A (en) * 1990-07-26 1991-07-23 Schering-Corporation Purification of human interleukin-4 from a CHO-cell line culture medium
CA2091170A1 (en) * 1990-09-06 1992-03-07 Marian L. Plunkett Use of il-4 to treat solid tumors
US5494662A (en) * 1992-04-27 1996-02-27 Ono Pharmaceutical Co., Ltd. Stimulator for bone formation
US5437986A (en) * 1994-06-22 1995-08-01 Schering Corporation Extraction of heterologous insoluble proteins from bacteria
US5716612A (en) * 1994-09-07 1998-02-10 Schering Corporation Use of IL-4 for potentiation of chemotherapeutic agents
US6242219B1 (en) * 1999-03-18 2001-06-05 Xoma (Us) Llc Methods for recombinant peptide production
US20040101825A1 (en) * 2001-09-26 2004-05-27 Van Meir Erwin G. Viruses targeted to hypoxic cells and tissues
US7285414B2 (en) * 2000-09-26 2007-10-23 Emory University Viruses targeted to hypoxic cells and tissues

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1432039A (en) * 1972-11-10 1976-04-14 Dai Nippon Sugar Mfg Co Ltd Method of treating microorganisms
US4364863A (en) * 1980-12-29 1982-12-21 Schering Corporation Extraction of interferon from bacteria
US4405601A (en) * 1981-05-21 1983-09-20 Cancer Research Center Extraction and purification of biologically active lymphokines
DE3432196A1 (de) * 1984-09-01 1986-03-06 Boehringer Ingelheim International GmbH, 6507 Ingelheim Neues mechanisches aufschlussverfahren von bakterienzellen zur isolierung von rekombinant hergestellten peptiden
DE3500681A1 (de) * 1985-01-11 1986-07-17 Hoechst Ag, 6230 Frankfurt Verfahren zur isolierung und reinigung von lymphokinen
US6916914B1 (en) * 1985-06-26 2005-07-12 Pharmacia & Upjohn Co. Purification of somatotropin from transformed microorganisms
US4675387A (en) * 1985-07-26 1987-06-23 E. I. Du Pont De Nemours And Company Method for extracting protein with organic acid
PT83761B (pt) * 1985-11-19 1989-06-30 Schering Biotech Corp Metodo para a producao de interleuquina-4 de mamifero
ZA872781B (en) * 1986-05-19 1987-10-05 Immunology Ventures B-cell stimulating factor
US4801686A (en) * 1986-09-04 1989-01-31 Immunex Corporation Purification of recombinant interleukin-1
US4912200A (en) * 1987-05-11 1990-03-27 Schering Corporation Extraction of granulocyte macrophage colony stimulating factor from bacteria

Also Published As

Publication number Publication date
JPH03500965A (ja) 1991-03-07
DK273490A (da) 1990-11-16
DE68913587T2 (de) 1994-06-16
JPH0716434B2 (ja) 1995-03-01
WO1989011541A1 (en) 1989-11-30
HU210428B (en) 1995-04-28
DE68913587D1 (de) 1994-04-14
US4958007A (en) 1990-09-18
AU3752289A (en) 1989-12-12
EP0342892A1 (de) 1989-11-23
EP0342892B1 (de) 1994-03-09
EP0414812A1 (de) 1991-03-06
CA1314831C (en) 1993-03-23
HUT54212A (en) 1991-01-28
AU632753B2 (en) 1993-01-14
HU894370D0 (en) 1990-12-28
ES2061991T3 (es) 1994-12-16
DK273490D0 (da) 1990-11-16

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee