ATE102924T1 - 1-(4-aminophenyl)-2-piperidinopropanon-derivate verfahren zu deren herstellung und therapeutische verwendung. - Google Patents

1-(4-aminophenyl)-2-piperidinopropanon-derivate verfahren zu deren herstellung und therapeutische verwendung.

Info

Publication number: ATE102924T1
Authority: AT; Austria
Prior art keywords: piperidinopropanone; aminophenyl; preparation; therapeutic use; derivatives process
Prior art date: 1989-10-30

Application number

AT90403078T

Other languages

English (en)

Inventor

Louis Lafon

Original Assignee

Lafon Labor

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-10-30

Filing date

1990-10-30

Publication date

1994-04-15

1990-10-30 Application filed by Lafon Labor filed Critical Lafon Labor

1994-04-15 Application granted granted Critical

1994-04-15 Publication of ATE102924T1 publication Critical patent/ATE102924T1/de

Links

230000001225 therapeutic effect Effects 0.000 title 1
TUCNEACPLKLKNU-UHFFFAOYSA-N acetyl Chemical compound C[C]=O TUCNEACPLKLKNU-UHFFFAOYSA-N 0.000 abstract 2
150000001875 compounds Chemical class 0.000 abstract 2
150000003839 salts Chemical class 0.000 abstract 2
125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
229940125692 cardiovascular agent Drugs 0.000 abstract 1
239000002327 cardiovascular agent Substances 0.000 abstract 1
239000003795 chemical substances by application Substances 0.000 abstract 1
IMCGHZIGRANKHV-AJNGGQMLSA-N tert-butyl (3s,5s)-2-oxo-5-[(2s,4s)-5-oxo-4-propan-2-yloxolan-2-yl]-3-propan-2-ylpyrrolidine-1-carboxylate Chemical compound O1C(=O)[C@H](C(C)C)C[C@H]1[C@H]1N(C(=O)OC(C)(C)C)C(=O)[C@H](C(C)C)C1 IMCGHZIGRANKHV-AJNGGQMLSA-N 0.000 abstract 1
230000000304 vasodilatating effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
- C07D295/104—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/108—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Medicinal Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Hydrogenated Pyridines (AREA)

AT90403078T 1989-10-30 1990-10-30 1-(4-aminophenyl)-2-piperidinopropanon-derivate verfahren zu deren herstellung und therapeutische verwendung. ATE102924T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR8914217A FR2653767B1 (fr)	1989-10-30	1989-10-30	Derives de 1-(aminophenyl)-2-piperidinopropanone, procede et utilisation en therapeutique.

Publications (1)

Publication Number	Publication Date
ATE102924T1 true ATE102924T1 (de)	1994-04-15

Family

ID=9386921

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT90403078T ATE102924T1 (de)	1989-10-30	1990-10-30	1-(4-aminophenyl)-2-piperidinopropanon-derivate verfahren zu deren herstellung und therapeutische verwendung.

Country Status (9)

Country	Link
US (1)	US5128349A (de)
EP (1)	EP0426562B1 (de)
JP (1)	JPH03209364A (de)
AT (1)	ATE102924T1 (de)
CA (1)	CA2028764A1 (de)
DE (1)	DE69007422T2 (de)
DK (1)	DK0426562T3 (de)
ES (1)	ES2062457T3 (de)
FR (1)	FR2653767B1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2450073C (en)	2001-07-25	2017-08-29	Biomarin Pharmaceutical Inc.	Compositions and methods for modulating blood-brain barrier transport
DE10344594A1 (de) *	2003-09-25	2005-05-12	Basf Ag	Verfahren zur Herstellung von Cyclododecanon
EP2671508B1 (de)	2005-04-28	2020-09-16	Proteus Digital Health, Inc.	Pharma-Informatiksystem
JP2010503710A (ja)	2006-09-18	2010-02-04	ラプトールファーマシューティカルインコーポレイテッド	受容体関連タンパク質（ｒａｐ）結合体の投与による肝障害の処置
ES2919563T3 (es)	2009-02-20	2022-07-27	Enhanx Biopharm Inc	Sistema de administración de medicamentos a base de glutatión
KR20180114970A (ko)	2009-05-06	2018-10-19	라보라토리 스킨 케어, 인크.	활성제-칼슘 포스페이트 입자 복합체를 포함하는 피부 전달 조성물 및 이들을 이용하는 방법
US20120077778A1 (en)	2010-09-29	2012-03-29	Andrea Bourdelais	Ladder-Frame Polyether Conjugates

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE1618005A1 (de) *	1966-09-22	1971-09-09	Thomae Gmbh Dr K	Verfahren zur Herstellung von neuen Amino-dihalogen-phenyl-aethylaminen
DE1618007A1 (de) *	1967-05-09	1970-10-29	Thomae Gmbh Dr K	Verfahren zur Herstellung von neuen Amino-monohalogenphenylaethanolaminen
GB1262965A (en) *	1969-03-21	1972-02-09	Ferrosan As	Butyrophenones
US4282206A (en) *	1979-11-15	1981-08-04	Westwood Pharmaceuticals Inc.	Method of protecting human skin from ultraviolet radiation
CA1250838A (fr) *	1983-10-14	1989-03-07	Louis Lafon	Procede de preparation de derives de 1-(acetylaminophenyl)-2-amino-propanone et les derives ainsi obtenus
FR2569184A1 (fr) *	1984-08-20	1986-02-21	Lafon Labor	Derives de 1-(aminophenyl) therapeutique et leur procede de preparation

1989
- 1989-10-30 FR FR8914217A patent/FR2653767B1/fr not_active Expired - Lifetime
1990
- 1990-10-29 US US07/604,802 patent/US5128349A/en not_active Expired - Fee Related
- 1990-10-29 CA CA002028764A patent/CA2028764A1/en not_active Abandoned
- 1990-10-30 JP JP2290950A patent/JPH03209364A/ja active Pending
- 1990-10-30 DK DK90403078.0T patent/DK0426562T3/da active
- 1990-10-30 ES ES90403078T patent/ES2062457T3/es not_active Expired - Lifetime
- 1990-10-30 DE DE69007422T patent/DE69007422T2/de not_active Expired - Fee Related
- 1990-10-30 EP EP90403078A patent/EP0426562B1/de not_active Expired - Lifetime
- 1990-10-30 AT AT90403078T patent/ATE102924T1/de not_active IP Right Cessation

Also Published As

Publication number	Publication date
CA2028764A1 (en)	1991-05-01
DE69007422T2 (de)	1994-07-14
JPH03209364A (ja)	1991-09-12
EP0426562A1 (de)	1991-05-08
FR2653767A1 (fr)	1991-05-03
DK0426562T3 (da)	1994-07-25
DE69007422D1 (de)	1994-04-21
EP0426562B1 (de)	1994-03-16
US5128349A (en)	1992-07-07
FR2653767B1 (fr)	1992-02-14
ES2062457T3 (es)	1994-12-16

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Legal Events

Date	Code	Title	Description
1995-01-15	UEP	Publication of translation of european patent specification
1996-07-15	REN	Ceased due to non-payment of the annual fee