ATE103338T1 - Verfahren zur herstellung von (-) 2difluoromethyl ornithin. - Google Patents
Verfahren zur herstellung von (-) 2difluoromethyl ornithin.Info
- Publication number
- ATE103338T1 ATE103338T1 AT89116001T AT89116001T ATE103338T1 AT E103338 T1 ATE103338 T1 AT E103338T1 AT 89116001 T AT89116001 T AT 89116001T AT 89116001 T AT89116001 T AT 89116001T AT E103338 T1 ATE103338 T1 AT E103338T1
- Authority
- AT
- Austria
- Prior art keywords
- ornithine
- production
- substituted
- ornithines
- piperidone
- Prior art date
Links
- VLCYCQAOQCDTCN-ZCFIWIBFSA-N α-difluoromethylornithine Chemical compound NCCC[C@@](N)(C(F)F)C(O)=O VLCYCQAOQCDTCN-ZCFIWIBFSA-N 0.000 title 1
- -1 (-) 2-substituted-ornithines Chemical class 0.000 abstract 1
- 150000001768 cations Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23893688A | 1988-08-31 | 1988-08-31 | |
| EP89116001A EP0357029B1 (de) | 1988-08-31 | 1989-08-30 | Verfahren zur Herstellung von (-) 2-Difluoromethyl Ornithin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE103338T1 true ATE103338T1 (de) | 1994-04-15 |
Family
ID=22899933
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT89116001T ATE103338T1 (de) | 1988-08-31 | 1989-08-30 | Verfahren zur herstellung von (-) 2difluoromethyl ornithin. |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP0357029B1 (de) |
| JP (1) | JP2816717B2 (de) |
| KR (1) | KR0152258B1 (de) |
| AT (1) | ATE103338T1 (de) |
| CA (1) | CA1319123C (de) |
| DE (1) | DE68914064T2 (de) |
| ES (1) | ES2053889T3 (de) |
| IE (1) | IE63529B1 (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4420751A1 (de) | 1994-06-15 | 1995-12-21 | Basf Ag | Verfahren zur Herstellung von enantiomerenreinen Lactamen |
| AU5526898A (en) * | 1996-12-13 | 1998-07-03 | Ilex Oncology, Inc. | Isomeric pharmaceutical formulation containing dfmo for the treatment of cancer |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1091661A (en) * | 1977-07-11 | 1980-12-16 | Philippe Bey | .alpha.-HALOMETHYL DERIVATIVES OF .alpha.-AMINO ACIDS |
-
1989
- 1989-08-25 CA CA000609462A patent/CA1319123C/en not_active Expired - Lifetime
- 1989-08-30 ES ES89116001T patent/ES2053889T3/es not_active Expired - Lifetime
- 1989-08-30 EP EP89116001A patent/EP0357029B1/de not_active Expired - Lifetime
- 1989-08-30 IE IE279289A patent/IE63529B1/en not_active IP Right Cessation
- 1989-08-30 AT AT89116001T patent/ATE103338T1/de not_active IP Right Cessation
- 1989-08-30 KR KR1019890012658A patent/KR0152258B1/ko not_active Expired - Lifetime
- 1989-08-30 DE DE68914064T patent/DE68914064T2/de not_active Expired - Lifetime
- 1989-08-31 JP JP1223361A patent/JP2816717B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JPH02188558A (ja) | 1990-07-24 |
| KR0152258B1 (ko) | 1998-10-01 |
| IE63529B1 (en) | 1995-05-03 |
| KR900003107A (ko) | 1990-03-23 |
| CA1319123C (en) | 1993-06-15 |
| DE68914064T2 (de) | 1994-06-30 |
| DE68914064D1 (de) | 1994-04-28 |
| ES2053889T3 (es) | 1994-08-01 |
| JP2816717B2 (ja) | 1998-10-27 |
| IE892792L (en) | 1990-02-28 |
| EP0357029A2 (de) | 1990-03-07 |
| EP0357029B1 (de) | 1994-03-23 |
| EP0357029A3 (de) | 1991-09-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| EELA | Cancelled due to lapse of time |