ATE103895T1 - N-arylierung von isatinen. - Google Patents

N-arylierung von isatinen.

Info

Publication number
ATE103895T1
ATE103895T1 AT89120863T AT89120863T ATE103895T1 AT E103895 T1 ATE103895 T1 AT E103895T1 AT 89120863 T AT89120863 T AT 89120863T AT 89120863 T AT89120863 T AT 89120863T AT E103895 T1 ATE103895 T1 AT E103895T1
Authority
AT
Austria
Prior art keywords
arylation
isatine
isatins
disclosed
reagents
Prior art date
Application number
AT89120863T
Other languages
English (en)
Inventor
James E Dombrowski
Phillip Gregory Mattingly
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Application granted granted Critical
Publication of ATE103895T1 publication Critical patent/ATE103895T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/94Bismuth compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/30Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32Oxygen atoms
    • C07D209/38Oxygen atoms in positions 2 and 3, e.g. isatin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/58[b]- or [c]-condensed
    • C07D209/60Naphtho [b] pyrroles; Hydrogenated naphtho [b] pyrroles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D219/00Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D219/00Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • C07D219/06Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D219/00Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • C07D219/08Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D221/00Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04Ortho- or peri-condensed ring systems
    • C07D221/18Ring systems of four or more rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Indole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
AT89120863T 1988-11-15 1989-11-10 N-arylierung von isatinen. ATE103895T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27179988A 1988-11-15 1988-11-15
EP89120863A EP0369344B1 (de) 1988-11-15 1989-11-10 N-Arylierung von Isatinen

Publications (1)

Publication Number Publication Date
ATE103895T1 true ATE103895T1 (de) 1994-04-15

Family

ID=23037139

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89120863T ATE103895T1 (de) 1988-11-15 1989-11-10 N-arylierung von isatinen.

Country Status (8)

Country Link
EP (1) EP0369344B1 (de)
JP (1) JPH02193966A (de)
KR (1) KR900007800A (de)
AT (1) ATE103895T1 (de)
AU (1) AU630122B2 (de)
CA (1) CA2002708A1 (de)
DE (1) DE68914403T2 (de)
ES (1) ES2054986T3 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5208228A (en) * 1989-11-13 1993-05-04 Merck & Co., Inc. Aminomacrolides and derivatives having immunosuppressive activity
US5162334A (en) * 1991-05-13 1992-11-10 Merck & Co., Inc. Amino O-alkyl, O-alkenyl and O-alkynlmacrolides having immunosuppressive activity
US5250678A (en) * 1991-05-13 1993-10-05 Merck & Co., Inc. O-aryl, O-alkyl, O-alkenyl and O-alkynylmacrolides having immunosuppressive activity
US5565560A (en) * 1991-05-13 1996-10-15 Merck & Co., Inc. O-Aryl,O-alkyl,O-alkenyl and O-alkynylmacrolides having immunosuppressive activity
US5189042A (en) * 1991-08-22 1993-02-23 Merck & Co. Inc. Fluoromacrolides having immunosuppressive activity
US5208241A (en) * 1991-09-09 1993-05-04 Merck & Co., Inc. N-heteroaryl, n-alkylheteroaryl, n-alkenylheteroaryl and n-alkynylheteroarylmacrolides having immunosuppressive activity
US5395752A (en) * 1993-03-19 1995-03-07 Ciba Corning Diagnostics Corp. Long emission wavelength chemiluminescent compounds and their use in test assays
DE4314318A1 (de) * 1993-04-30 1994-11-03 Henkel Kgaa Isatinderivate zum Färben von keratinhaltigen Fasern
US5693648A (en) * 1994-09-30 1997-12-02 Merck & Co., Inc. O-aryl, O-alkyl, O-alkenyl and O-alkynyl-macrolides having immunosuppressive activity
WO2001002394A1 (en) 1999-07-01 2001-01-11 Geron Corporation Substituted indole compounds and their use for the treatment of cancer
DE102006046330A1 (de) * 2006-09-28 2008-04-03 Bayer Materialscience Ag Polycarbonate und Copolycarbonate mit verbesserter Metallhaftung
EP2527324A4 (de) 2010-01-20 2013-08-07 Mitsubishi Gas Chemical Co Cyanatesterverbindung und härteprodukt daraus

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3279029D1 (en) * 1981-12-11 1988-10-20 Welsh Nat School Med Luminescent labelling materials and procedures

Also Published As

Publication number Publication date
ES2054986T3 (es) 1994-08-16
DE68914403T2 (de) 1994-07-21
DE68914403D1 (de) 1994-05-11
EP0369344B1 (de) 1994-04-06
AU630122B2 (en) 1992-10-22
JPH02193966A (ja) 1990-07-31
AU4448389A (en) 1990-05-24
EP0369344A1 (de) 1990-05-23
CA2002708A1 (en) 1990-05-15
KR900007800A (ko) 1990-06-02

Similar Documents

Publication Publication Date Title
NO883304D0 (no) Horisontalt leddet lukkepanel av polykarbonat.
DE3667961D1 (de) Glasplatten-fertigungsmaschine.
GB8704031D0 (en) Transparent light emitter drive update
FI854711A0 (fi) Syntetisering av 7-halo-7 -deoxilincomyciner.
FI882845L (fi) Tvaerriktad glansregulator.
ATE68129T1 (de) Glasbeschichtungsverfahren und so hergestellter gegenstand.
NO880715D0 (no) Glassrute-tetningsanordning.
ATE103895T1 (de) N-arylierung von isatinen.
ATE83424T1 (de) Formdichtungsgestaltung zum einkapseln einer glasscheibe mit einer flachdichtung.
DE68908614D1 (de) Vorrichtung zur Herstellung von gebogenen Glasscheiben.
NO168949C (no) Anordning for fremstilling av gass av faste brennstoffer
KR880700775A (ko) 유리의 제조법
GR81852B (de)
FI891878L (fi) Glasoegonbaoge.
KR880700774A (ko) 유리의 제조법
FR2592636B1 (fr) Conteneur a verre
DK392287A (da) Fremgangsmaade til fremstilling af penem-allyl-estere samt mellemprodukt til brug ved fremgangsmaaden
FI872237L (fi) Glasoegonbaoge.
EP0277585A3 (de) Spinndüse zum Herstellen von Glasfasern
FI880372L (fi) Process foer syntes av azetidin och dess nya mellanprodukter.
DK0433845T3 (da) Fremgangsmåde til fremstilling af 2-acylamino-9-acyl-6-halogen-puriner
GB8613187D0 (en) Light source
NO881849L (no) Fremgangsmaate ved montering av et lyspanel.
FR2609280B2 (fr) Conteneur a verre
FI881154A0 (fi) Foerfarande foer framstaellning av 5-hydroxidprafenon och dess syraadditionssalter.