ATE103924T1 - Verfahren zur herstellung von kuprat-komplexen hoeherer ordnung. - Google Patents

Verfahren zur herstellung von kuprat-komplexen hoeherer ordnung.

Info

Publication number: ATE103924T1
Authority: AT; Austria
Prior art keywords: higher order; complex; cuprate; preparation; order cuprate
Prior art date: 1987-06-09

Application number

AT88109047T

Other languages

English (en)

Inventor

Arthur Lee Campbell

James Richard Behling

Original Assignee

Searle & Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-06-09

Filing date

1988-06-07

Publication date

1994-04-15

1988-06-07 Application filed by Searle & Co filed Critical Searle & Co

1994-04-15 Application granted granted Critical

1994-04-15 Publication of ATE103924T1 publication Critical patent/ATE103924T1/de

Links

238000000034 method Methods 0.000 title abstract 3
229910052799 carbon Inorganic materials 0.000 abstract 4
OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 2
238000006243 chemical reaction Methods 0.000 abstract 2
KXCAEQNNTZANTK-UHFFFAOYSA-N stannane Chemical compound [SnH4] KXCAEQNNTZANTK-UHFFFAOYSA-N 0.000 abstract 2
229910000080 stannane Inorganic materials 0.000 abstract 2
230000015572 biosynthetic process Effects 0.000 abstract 1
238000011065 in-situ storage Methods 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
229940094443 oxytocics prostaglandins Drugs 0.000 abstract 1
150000003180 prostaglandins Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F1/00—Compounds containing elements of Groups 1 or 11 of the Periodic Table
- C07F1/08—Copper compounds
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/22—Tin compounds
- C07F7/2208—Compounds having tin linked only to carbon, hydrogen and/or halogen

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

AT88109047T 1987-06-09 1988-06-07 Verfahren zur herstellung von kuprat-komplexen hoeherer ordnung. ATE103924T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US07/059,695 US4777275A (en)	1987-06-09	1987-06-09	Process of preparing higher order cuprate complexes
EP88109047A EP0294757B1 (de)	1987-06-09	1988-06-07	Verfahren zur Herstellung von Kuprat-Komplexen höherer Ordnung

Publications (1)

Publication Number	Publication Date
ATE103924T1 true ATE103924T1 (de)	1994-04-15

Family

ID=22024644

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT88109047T ATE103924T1 (de)	1987-06-09	1988-06-07	Verfahren zur herstellung von kuprat-komplexen hoeherer ordnung.

Country Status (7)

Country	Link
US (1)	US4777275A (de)
EP (1)	EP0294757B1 (de)
JP (1)	JP2667875B2 (de)
AT (1)	ATE103924T1 (de)
CA (1)	CA1311490C (de)
DE (1)	DE3888872T2 (de)
ES (1)	ES2062999T3 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5011958A (en) *	1987-06-08	1991-04-30	G. D. Searle & Co.	Process for preparing higher order cuprate complexes
US5166382A (en) *	1990-04-04	1992-11-24	Regents Of The University Of California	Transmetalations from zirconium to copper intermediates
US5072010A (en) *	1990-04-04	1991-12-10	University Of California	Transmetalations from zirconium to copper intermediates
US5055604A (en) *	1990-04-17	1991-10-08	G. D. Searle & Co.	Process for preparing prostaglandin analogs using organozirconium compounds
US5405981A (en) *	1993-03-26	1995-04-11	The Regents Of The University Of California	Copper catalyzed coupling reactions
US5684177A (en) *	1996-05-17	1997-11-04	Torcan Chemical Ltd.	Misoprostol
WO1998021179A1 (fr) *	1996-11-14	1998-05-22	Fuji Yakuhin Kogyo Kabushiki Kaisha	Procede de preparation de prostaglandines
US6388128B1 (en)	1998-10-05	2002-05-14	Alcon Manufacturing, Ltd.	Stannane synthesis of prostanoids
HU231185B1 (hu) *	2017-07-11	2021-07-28	CHINOIN Gyógyszer és Vegyészeti Termékek Gyára Zrt.	Eljárás Misoprostol előállítására és tisztítására

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US30287A (en) *		1860-10-09		Propelling cars on railroads
US3965143A (en) *	1974-03-26	1976-06-22	G. D. Searle & Co.	16-Oxygenated prostanoic acid derivatives
USRE30287E (en)	1974-03-26	1980-05-27	Gist-Brocades N.V.	19 Hydroxy prostaglandins
US4322543A (en) *	1979-11-28	1982-03-30	G. D. Searle & Co.	4,5-Unsaturated prostanoic acid derivatives
US4271314A (en) *	1979-11-28	1981-06-02	G. D. Searle & Co.	4,5-Unsaturated prostanoic acid derivatives
US4529812A (en) *	1983-02-02	1985-07-16	G. D. Searle & Co.	3-Oxaprostaglandins
US4543421A (en) *	1983-05-11	1985-09-24	Miles Laboratories, Inc.	Conjugate addition of organocuprates generated from copper (I) cyanide and vinyl stannanes useful in prostaglandin analog synthesis
US4499296A (en) *	1983-11-14	1985-02-12	G. D. Searle & Co.	Omega cycloalkyl prostaglandins
US4578505A (en) *	1984-09-04	1986-03-25	G. D. Searle & Co.	Allenic prostanoic acid derivatives
US4785124A (en) *	1987-06-08	1988-11-15	G. D. Searle & Co.	Process for preparing higher order cuprate complexes

1987
- 1987-06-09 US US07/059,695 patent/US4777275A/en not_active Expired - Lifetime
1988
- 1988-06-07 AT AT88109047T patent/ATE103924T1/de not_active IP Right Cessation
- 1988-06-07 ES ES88109047T patent/ES2062999T3/es not_active Expired - Lifetime
- 1988-06-07 EP EP88109047A patent/EP0294757B1/de not_active Expired - Lifetime
- 1988-06-07 DE DE3888872T patent/DE3888872T2/de not_active Expired - Fee Related
- 1988-06-07 CA CA000568869A patent/CA1311490C/en not_active Expired - Lifetime
- 1988-06-08 JP JP63141445A patent/JP2667875B2/ja not_active Expired - Fee Related

Also Published As

Publication number	Publication date
EP0294757A3 (en)	1990-07-11
US4777275A (en)	1988-10-11
JPS63316786A (ja)	1988-12-26
EP0294757A2 (de)	1988-12-14
EP0294757B1 (de)	1994-04-06
JP2667875B2 (ja)	1997-10-27
DE3888872T2 (de)	1994-08-11
ES2062999T3 (es)	1995-01-01
DE3888872D1 (de)	1994-05-11
CA1311490C (en)	1992-12-15

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Legal Events

Date	Code	Title	Description
1995-01-15	UEP	Publication of translation of european patent specification
2007-03-15	REN	Ceased due to non-payment of the annual fee