ATE104551T1 - S-adenosylmethionin zur behandlung von pankreatitis und der immunabstossung des pankreastransplantates. - Google Patents

S-adenosylmethionin zur behandlung von pankreatitis und der immunabstossung des pankreastransplantates.

Info

Publication number: ATE104551T1
Authority: AT; Austria
Prior art keywords: pancreatitis; treatment; pct; adenosylmethionine; pancreas transplant
Prior art date: 1989-01-14

Application number

AT9090902247T

Other languages

English (en)

Inventor

Ian V Hutchinson

Joan M Braganza

Original Assignee

Bioresearch Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-01-14

Filing date

1990-01-10

Publication date

1994-05-15

1990-01-10 Application filed by Bioresearch Spa filed Critical Bioresearch Spa

1994-05-15 Application granted granted Critical

1994-05-15 Publication of ATE104551T1 publication Critical patent/ATE104551T1/de

Links

206010033645 Pancreatitis Diseases 0.000 title abstract 2
MEFKEPWMEQBLKI-AIRLBKTGSA-N S-adenosyl-L-methioninate Chemical compound O[C@@H]1[C@H](O)[C@@H](C[S+](CC[C@H](N)C([O-])=O)C)O[C@H]1N1C2=NC=NC(N)=C2N=C1 MEFKEPWMEQBLKI-AIRLBKTGSA-N 0.000 title abstract 2
229960001570 ademetionine Drugs 0.000 title abstract 2
210000000496 pancreas Anatomy 0.000 title abstract 2
PMATZTZNYRCHOR-CGLBZJNRSA-N Cyclosporin A Chemical compound CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O PMATZTZNYRCHOR-CGLBZJNRSA-N 0.000 abstract 1
229930105110 Cyclosporin A Natural products 0.000 abstract 1
108010036949 Cyclosporine Proteins 0.000 abstract 1
206010052779 Transplant rejections Diseases 0.000 abstract 1
229960001265 ciclosporin Drugs 0.000 abstract 1
229930182912 cyclosporin Natural products 0.000 abstract 1
230000002265 prevention Effects 0.000 abstract 1
239000012747 synergistic agent Substances 0.000 abstract 1
230000001225 therapeutic effect Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Epidemiology (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
Genetics & Genomics (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Transplantation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Saccharide Compounds (AREA)

AT9090902247T 1989-01-14 1990-01-10 S-adenosylmethionin zur behandlung von pankreatitis und der immunabstossung des pankreastransplantates. ATE104551T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB898900812A GB8900812D0 (en)	1989-01-14	1989-01-14	Pharmaceutical method and compositions
PCT/EP1990/000048 WO1990007928A1 (en)	1989-01-14	1990-01-10	S-adenosyl-methionine in the treatment of pancreatitis and of the immuno rejection in the pancreas transplant

Publications (1)

Publication Number	Publication Date
ATE104551T1 true ATE104551T1 (de)	1994-05-15

Family

ID=10650037

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT9090902247T ATE104551T1 (de)	1989-01-14	1990-01-10	S-adenosylmethionin zur behandlung von pankreatitis und der immunabstossung des pankreastransplantates.

Country Status (15)

Country	Link
US (1)	US5196402A (de)
EP (1)	EP0408711B1 (de)
JP (1)	JPH03503289A (de)
KR (1)	KR910700055A (de)
AT (1)	ATE104551T1 (de)
AU (1)	AU630159B2 (de)
CA (1)	CA2026580A1 (de)
DE (1)	DE69008258T2 (de)
DK (1)	DK0408711T3 (de)
ES (1)	ES2055415T3 (de)
GB (1)	GB8900812D0 (de)
HU (1)	HU206626B (de)
RU (1)	RU2014837C1 (de)
WO (1)	WO1990007928A1 (de)
ZA (1)	ZA90241B (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1243859B (it) *	1990-10-23	1994-06-28	Bioresearch Spa	Composizioni farmaceutiche comprendenti associazioni fra sali di s-adenosil-l-metionina e acido 5-metil (o 5-formil)-tetraidrofolico per la terapia di complicanze neurologiche negli ammalati di aids.
US6492349B1 (en)	1993-03-31	2002-12-10	Nutramax Laboratories, Inc.	Aminosugar and glycosaminoglycan composition for the treatment and repair of connective tissue
US5508262A (en) *	1993-12-15	1996-04-16	University Of South Florida	Interleukin-1 receptor antagonist decreases severity of acute pancreatitis
US5747461A (en) *	1994-07-26	1998-05-05	Markov; Angel K.	Synergistic administration of cyclosporine and fructose diphosphate
US5723116A (en) *	1995-01-06	1998-03-03	University Of South Florida	Decreased mortality of severe acute pancreatitis following proximal cytokine blockade
GB2312621B (en) *	1996-05-02	1998-03-11	Pharma Nord Uk Limited	Anti-oxidant medicament
US6255295B1 (en)	1996-12-23	2001-07-03	Nutramax Laboratories, Inc.	Aminosugar, glycosaminoglycan or glycosaminoglycan-like compounds, and s-adenosylmethionine composition for the protection, treatment, repair, and reduction of inflammation of connective tissue
US6063600A (en) *	1997-05-23	2000-05-16	Uab Research Foundation	DNA encoding canine interleukin-1 receptor antagonist
US6399093B1 (en)	1999-05-19	2002-06-04	Advanced Medical Instruments	Method and composition to treat musculoskeletal disorders
AU2003278929A1 (en) *	2002-10-18	2004-05-13	Amylin Pharmaceuticals, Inc.	Treatment of pancreatitis with amylin
US20050272687A1 (en) *	2004-06-08	2005-12-08	Hebert Rolland F	Stable S-adenosyl-l-methionine
RU2423692C2 (ru) *	2005-04-27	2011-07-10	ЮЭмЭн ФАРМА ИНК.	Вещества для профилактики и лечения панкреатита
US20090012036A1 (en) *	2005-05-24	2009-01-08	Hebert Rolland F	Stable S-adenosyl-L-methionine
US20100004191A1 (en) *	2008-07-01	2010-01-07	Rolland F Hebert	Compositions of S-adenosyl-L-methionine.
WO2011122134A1 (ja)	2010-03-30	2011-10-06	新日本製鐵株式会社	高周波焼入れ用鋼、高周波焼入れ用粗形材、その製造方法、及び高周波焼入れ鋼部品
KR101748053B1 (ko)	2012-10-17	2017-06-15	메틸레이션 사이언시즈 인터내셔널 에스알엘	S-아데노실메티오닌 및 갈산 에스테르가 포함된 조성물
EP4712796A2 (de)	2023-05-15	2026-03-25	Bonafide Health, LLC	Schlafverbessernde zusammensetzungen und verfahren zur verwendung

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1169772B (it) *	1983-08-24	1987-06-03	Bioresearch Spa	Composizioni terapeutiche per uso orale contenenti sali stabili della s-adenosil-l-metionina
IT1200589B (it) *	1985-02-14	1989-01-27	Gibipharma Spa	Derivati naturali attivita farmagologica
EP0395656B1 (de) *	1987-10-09	1992-09-02	ZAPPIA, Vincenzo	Lipophile salze von s-adenosyl-l-methionin (sam) mit acyltaurinderivaten

1989
- 1989-01-14 GB GB898900812A patent/GB8900812D0/en active Pending
1990
- 1990-01-10 AU AU50260/90A patent/AU630159B2/en not_active Ceased
- 1990-01-10 JP JP2502570A patent/JPH03503289A/ja active Pending
- 1990-01-10 WO PCT/EP1990/000048 patent/WO1990007928A1/en not_active Ceased
- 1990-01-10 ES ES90902247T patent/ES2055415T3/es not_active Expired - Lifetime
- 1990-01-10 CA CA002026580A patent/CA2026580A1/en not_active Abandoned
- 1990-01-10 KR KR1019900702011A patent/KR910700055A/ko not_active Ceased
- 1990-01-10 DK DK90902247.7T patent/DK0408711T3/da active
- 1990-01-10 US US07/573,211 patent/US5196402A/en not_active Expired - Fee Related
- 1990-01-10 AT AT9090902247T patent/ATE104551T1/de not_active IP Right Cessation
- 1990-01-10 EP EP90902247A patent/EP0408711B1/de not_active Expired - Lifetime
- 1990-01-10 HU HU901516A patent/HU206626B/hu not_active IP Right Cessation
- 1990-01-10 DE DE69008258T patent/DE69008258T2/de not_active Expired - Fee Related
- 1990-01-12 ZA ZA90241A patent/ZA90241B/xx unknown
- 1990-09-13 RU SU904831272A patent/RU2014837C1/ru active

Also Published As

Publication number	Publication date
EP0408711B1 (de)	1994-04-20
ES2055415T3 (es)	1994-08-16
HUT54893A (en)	1991-04-29
RU2014837C1 (ru)	1994-06-30
DE69008258T2 (de)	1994-08-04
DK0408711T3 (da)	1994-06-06
AU630159B2 (en)	1992-10-22
WO1990007928A1 (en)	1990-07-26
CA2026580A1 (en)	1990-07-15
HU206626B (en)	1992-12-28
KR910700055A (ko)	1991-03-13
ZA90241B (en)	1991-03-27
HU901516D0 (en)	1991-03-28
EP0408711A1 (de)	1991-01-23
GB8900812D0 (en)	1989-03-08
DE69008258D1 (de)	1994-05-26
AU5026090A (en)	1990-08-13
JPH03503289A (ja)	1991-07-25
US5196402A (en)	1993-03-23

Legal Events

Date	Code	Title	Description
1994-11-15	UEP	Publication of translation of european patent specification
1998-10-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
DE69008258D1 (de)	1994-05-26	S-adenosylmethionin zur behandlung von pankreatitis und der immunabstossung des pankreastransplantates.
ATE185548T1 (de)	1999-10-15	Verwendung von n-arylmethylen ethylendiamintriacetate, n-arylmethylen iminodiacetat oder n,n'-diarylmethylen ethylendiamindiacetat gegen oxidativen stress
DE59905954D1 (de)	2003-07-17	Dialkylfumarate zur behandlung von autoimmunerkrankungen
EP0675708A1 (de)	1995-10-11	Pharmazeutische und dermokosmetische mittel enthaltend pferdecolostrum.
ID29393A (id)	2001-08-30	Komposisi pengobatan kanker dan metoda penggunaan minyak-minyak esensil tanaman alamiah
ATE221781T1 (de)	2002-08-15	Angiostatische verbindungen und zusammensetzungen zur behandlung des glc1a glaukoms
DE69022953D1 (de)	1995-11-16	Zusammensetzungen zur Behandlung von Fettablagerungen.
ATE240115T1 (de)	2003-05-15	Zusammensetzung zur vorbeugung und/oder behandlung der atherosklerose
PL321088A1 (en)	1997-11-24	Recombined antaginists of il-5 suitable in treating disorders associated with il-5
ATE152628T1 (de)	1997-05-15	Verwendung von parathormone, seinen biologisch aktiven fragmenten oder von verwandten peptiden zur behandlung von schwangerschaft
DE69803773D1 (de)	2002-03-21	Yohimbine und arginin enthaltende zusammensetzung zur behandlung der erektilen fehlfunktion
ATE190843T1 (de)	2000-04-15	Zubereitungen zur behandlung von impotenz, die ein alpha-1 inhibitor und ein alpha-2 inhibitor enthalten
ZA943171B (en)	1995-01-11	Thrombin-inhibitors.
ATE179164T1 (de)	1999-05-15	Hiv-proteaseinhibitoren
DE69526584D1 (de)	2002-06-06	Verwendung von immunosuppressiva zur behandlung der schizophrenie
ATE193206T1 (de)	2000-06-15	Zusammensetzung zur behandlung oder vorbeugung von herpes
DE69023006D1 (de)	1995-11-16	Verfahren zur behandlung von thrombocytopenie und dafür geeignete pharmazeutische zusammensetzungen.
MX9300205A (es)	1994-07-29	Compuestos policiclicos disubstituidos y composicion farmaceutica que los contiene.
DE69006360D1 (de)	1994-03-10	L-alpha-glycerophosphoryl-d-myoinositol zur behandlung peripherer neuropathien und cerebropathien.
DE69427116D1 (de)	2001-05-23	Verwendung von 4'-iodo - 4 - deoxydoxorubicin zur behandlung von amyloidosis
GB9015774D0 (en)	1990-09-05	Novel treatment
ATE165509T1 (de)	1998-05-15	Avermectine und milbemycine zur behandlung von parazitären infektionen beim hund