ZA90241B - Therapeutic compositions comprising s-adenosyl-methionine and use of the same in the therapeutic treatment of pancreatitis and of the immuno rejection in the pancreas transplant - Google Patents

Therapeutic compositions comprising s-adenosyl-methionine and use of the same in the therapeutic treatment of pancreatitis and of the immuno rejection in the pancreas transplant

Info

Publication number: ZA90241B
Authority: ZA; South Africa
Prior art keywords: adenosyl; pancreatitis; methionine; rejection; immuno
Prior art date: 1989-01-14

Application number

ZA90241A

Other languages

English (en)

Inventor

Ian V Hutchinson

V Hutchinson Ian

Joan M Braganza

M Braganza Joan

Original Assignee

Bioresearch S P A Italian Join

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-01-14

Filing date

1990-01-12

Publication date

1991-03-27

1990-01-12 Application filed by Bioresearch S P A Italian Join filed Critical Bioresearch S P A Italian Join

1991-03-27 Publication of ZA90241B publication Critical patent/ZA90241B/xx

Links

230000001225 therapeutic effect Effects 0.000 title abstract 3
206010033645 Pancreatitis Diseases 0.000 title abstract 2
MEFKEPWMEQBLKI-AIRLBKTGSA-N S-adenosyl-L-methioninate Chemical compound O[C@@H]1[C@H](O)[C@@H](C[S+](CC[C@H](N)C([O-])=O)C)O[C@H]1N1C2=NC=NC(N)=C2N=C1 MEFKEPWMEQBLKI-AIRLBKTGSA-N 0.000 title abstract 2
229960001570 ademetionine Drugs 0.000 title abstract 2
239000000203 mixture Substances 0.000 title abstract 2
210000000496 pancreas Anatomy 0.000 title abstract 2
PMATZTZNYRCHOR-CGLBZJNRSA-N Cyclosporin A Chemical compound CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O PMATZTZNYRCHOR-CGLBZJNRSA-N 0.000 abstract 1
229930105110 Cyclosporin A Natural products 0.000 abstract 1
108010036949 Cyclosporine Proteins 0.000 abstract 1
206010052779 Transplant rejections Diseases 0.000 abstract 1
229960001265 ciclosporin Drugs 0.000 abstract 1
229930182912 cyclosporin Natural products 0.000 abstract 1
230000002265 prevention Effects 0.000 abstract 1
239000012747 synergistic agent Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Epidemiology (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
Genetics & Genomics (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Transplantation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Saccharide Compounds (AREA)

ZA90241A 1989-01-14 1990-01-12 Therapeutic compositions comprising s-adenosyl-methionine and use of the same in the therapeutic treatment of pancreatitis and of the immuno rejection in the pancreas transplant ZA90241B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB898900812A GB8900812D0 (en)	1989-01-14	1989-01-14	Pharmaceutical method and compositions

Publications (1)

Publication Number	Publication Date
ZA90241B true ZA90241B (en)	1991-03-27

Family

ID=10650037

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA90241A ZA90241B (en)	1989-01-14	1990-01-12	Therapeutic compositions comprising s-adenosyl-methionine and use of the same in the therapeutic treatment of pancreatitis and of the immuno rejection in the pancreas transplant

Country Status (15)

Country	Link
US (1)	US5196402A (de)
EP (1)	EP0408711B1 (de)
JP (1)	JPH03503289A (de)
KR (1)	KR910700055A (de)
AT (1)	ATE104551T1 (de)
AU (1)	AU630159B2 (de)
CA (1)	CA2026580A1 (de)
DE (1)	DE69008258T2 (de)
DK (1)	DK0408711T3 (de)
ES (1)	ES2055415T3 (de)
GB (1)	GB8900812D0 (de)
HU (1)	HU206626B (de)
RU (1)	RU2014837C1 (de)
WO (1)	WO1990007928A1 (de)
ZA (1)	ZA90241B (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1243859B (it) *	1990-10-23	1994-06-28	Bioresearch Spa	Composizioni farmaceutiche comprendenti associazioni fra sali di s-adenosil-l-metionina e acido 5-metil (o 5-formil)-tetraidrofolico per la terapia di complicanze neurologiche negli ammalati di aids.
US6492349B1 (en) *	1993-03-31	2002-12-10	Nutramax Laboratories, Inc.	Aminosugar and glycosaminoglycan composition for the treatment and repair of connective tissue
US5508262A (en) *	1993-12-15	1996-04-16	University Of South Florida	Interleukin-1 receptor antagonist decreases severity of acute pancreatitis
US5747461A (en) *	1994-07-26	1998-05-05	Markov; Angel K.	Synergistic administration of cyclosporine and fructose diphosphate
US5723116A (en) *	1995-01-06	1998-03-03	University Of South Florida	Decreased mortality of severe acute pancreatitis following proximal cytokine blockade
GB2312621B (en) *	1996-05-02	1998-03-11	Pharma Nord Uk Limited	Anti-oxidant medicament
US6255295B1 (en)	1996-12-23	2001-07-03	Nutramax Laboratories, Inc.	Aminosugar, glycosaminoglycan or glycosaminoglycan-like compounds, and s-adenosylmethionine composition for the protection, treatment, repair, and reduction of inflammation of connective tissue
US6063600A (en) *	1997-05-23	2000-05-16	Uab Research Foundation	DNA encoding canine interleukin-1 receptor antagonist
US6399093B1 (en)	1999-05-19	2002-06-04	Advanced Medical Instruments	Method and composition to treat musculoskeletal disorders
WO2004037168A2 (en) *	2002-10-18	2004-05-06	Amylin Pharmaceuticals, Inc.	Treatment of pancreatitis with amylin
US20050272687A1 (en) *	2004-06-08	2005-12-08	Hebert Rolland F	Stable S-adenosyl-l-methionine
EP1879027B1 (de) *	2005-04-27	2013-06-12	CytoPathfinder, Inc.	Mittel zur vorbeugung und behandlung einer pankreatitis
US20090012036A1 (en) *	2005-05-24	2009-01-08	Hebert Rolland F	Stable S-adenosyl-L-methionine
US20100004191A1 (en) *	2008-07-01	2010-01-07	Rolland F Hebert	Compositions of S-adenosyl-L-methionine.
US9039962B2 (en)	2010-03-30	2015-05-26	Nippon Steel & Sumitomo Metal Corporation	Steel for induction hardening, roughly shaped material for induction hardening, producing method thereof, and induction hardening steel part
JP5877935B2 (ja) *	2012-10-17	2016-03-08	メチレーション・サイエンシーズ・インターナショナル・ソサイアティーズ・ウィズ・リストリクティッド・ライアビリティＭｅｔｈｙｌａｔｉｏｎＳｃｉｅｎｃｅｓＩｎｔｅｒｎａｔｉｏｎａｌＳｒｌ	Ｓ−アデノシルメチオニンおよび没食子酸エステルを含む組成物
WO2024238657A2 (en)	2023-05-15	2024-11-21	Bonafide Health, Llc	Sleep-improving compositions and methods of use

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1169772B (it) *	1983-08-24	1987-06-03	Bioresearch Spa	Composizioni terapeutiche per uso orale contenenti sali stabili della s-adenosil-l-metionina
IT1200589B (it) *	1985-02-14	1989-01-27	Gibipharma Spa	Derivati naturali attivita farmagologica
ATE80165T1 (de) *	1987-10-09	1992-09-15	Vincenzo Zappia	Lipophile salze von s-adenosyl-l-methionin (sam) mit acyltaurinderivaten.

1989
- 1989-01-14 GB GB898900812A patent/GB8900812D0/en active Pending
1990
- 1990-01-10 DE DE69008258T patent/DE69008258T2/de not_active Expired - Fee Related
- 1990-01-10 DK DK90902247.7T patent/DK0408711T3/da active
- 1990-01-10 ES ES90902247T patent/ES2055415T3/es not_active Expired - Lifetime
- 1990-01-10 WO PCT/EP1990/000048 patent/WO1990007928A1/en not_active Ceased
- 1990-01-10 KR KR1019900702011A patent/KR910700055A/ko not_active Ceased
- 1990-01-10 JP JP2502570A patent/JPH03503289A/ja active Pending
- 1990-01-10 US US07/573,211 patent/US5196402A/en not_active Expired - Fee Related
- 1990-01-10 EP EP90902247A patent/EP0408711B1/de not_active Expired - Lifetime
- 1990-01-10 AT AT9090902247T patent/ATE104551T1/de not_active IP Right Cessation
- 1990-01-10 AU AU50260/90A patent/AU630159B2/en not_active Ceased
- 1990-01-10 HU HU901516A patent/HU206626B/hu not_active IP Right Cessation
- 1990-01-10 CA CA002026580A patent/CA2026580A1/en not_active Abandoned
- 1990-01-12 ZA ZA90241A patent/ZA90241B/xx unknown
- 1990-09-13 RU SU904831272A patent/RU2014837C1/ru active

Also Published As

Publication number	Publication date
DE69008258T2 (de)	1994-08-04
AU5026090A (en)	1990-08-13
ATE104551T1 (de)	1994-05-15
GB8900812D0 (en)	1989-03-08
DK0408711T3 (da)	1994-06-06
AU630159B2 (en)	1992-10-22
JPH03503289A (ja)	1991-07-25
ES2055415T3 (es)	1994-08-16
EP0408711B1 (de)	1994-04-20
HUT54893A (en)	1991-04-29
HU901516D0 (en)	1991-03-28
US5196402A (en)	1993-03-23
HU206626B (en)	1992-12-28
RU2014837C1 (ru)	1994-06-30
EP0408711A1 (de)	1991-01-23
CA2026580A1 (en)	1990-07-15
KR910700055A (ko)	1991-03-13
DE69008258D1 (de)	1994-05-26
WO1990007928A1 (en)	1990-07-26

Publication	Publication Date	Title
ZA90241B (en)	1991-03-27	Therapeutic compositions comprising s-adenosyl-methionine and use of the same in the therapeutic treatment of pancreatitis and of the immuno rejection in the pancreas transplant
GR3024022T3 (en)	1997-10-31	Pharmaceutical and dermocosmetic compositions containing equine colostrum.
PL349028A1 (en)	2002-07-01	Cancer treatment composition and method using natural plant essential oils
CZ540990A3 (en)	1996-09-11	Microbicidal agent
ATE185548T1 (de)	1999-10-15	Verwendung von n-arylmethylen ethylendiamintriacetate, n-arylmethylen iminodiacetat oder n,n'-diarylmethylen ethylendiamindiacetat gegen oxidativen stress
IL101145A0 (en)	1992-11-15	Pharmaceutical compositions containing synergistic combinations of nucleoside derivatives
GB2288732B (en)	1998-04-29	Pharmaceutical compositions
NL300787I1 (de)	2016-04-05
GR3024667T3 (en)	1997-12-31	Cosmetical or pharmaceutical compositions comprising deacylated glycerophospholipids for topical use.
EA199700032A1 (ru)	1997-12-30	Дезинфицирующий состав "велтолен"
PL318298A1 (en)	1997-06-09	Thiopyridil compounds for fighting against heliobacter
GB2314019B (en)	2000-03-15	The use of L-Lysine in the treatment of hair loss
ZA943171B (en)	1995-01-11	Thrombin-inhibitors.
GR3034142T3 (en)	2000-11-30	Composition for the treatment or prevention of herpes
NZ237739A (en)	1993-09-27	Pharmaceutical composition of a complement inhibitor and an immunosuppressant with cyclosporin a-like activity, and its use
IL110289A0 (en)	1994-10-21	Pharmaceutical compositions comprising 4'-iodo-4'- deoxydoxorubicin for treating amyloidosis
GB9015774D0 (en)	1990-09-05	Novel treatment
IL98850A0 (en)	1992-07-15	Pristinamycin derivative and its preparation