ATE106072T1 - Platinkomplexe mit einzelnen isomeren von neoalkylsäuren. - Google Patents

Platinkomplexe mit einzelnen isomeren von neoalkylsäuren.

Info

Publication number
ATE106072T1
ATE106072T1 AT89402320T AT89402320T ATE106072T1 AT E106072 T1 ATE106072 T1 AT E106072T1 AT 89402320 T AT89402320 T AT 89402320T AT 89402320 T AT89402320 T AT 89402320T AT E106072 T1 ATE106072 T1 AT E106072T1
Authority
AT
Austria
Prior art keywords
acids
neoalkylic
platinum complexes
individual isomers
complexes
Prior art date
Application number
AT89402320T
Other languages
English (en)
Inventor
Paul A Tremblay
Frank Pilkiewicz
Mathew Cherian
Joel Portnoff
Robert P Lenk
Original Assignee
Liposome Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Liposome Co Inc filed Critical Liposome Co Inc
Application granted granted Critical
Publication of ATE106072T1 publication Critical patent/ATE106072T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C53/00—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen
    • C07C53/126—Acids containing more than four carbon atoms
    • C07C53/128—Acids containing more than four carbon atoms the carboxylic group being bound to a carbon atom bound to at least two other carbon atoms, e.g. neo-acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT89402320T 1988-08-22 1989-08-22 Platinkomplexe mit einzelnen isomeren von neoalkylsäuren. ATE106072T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US23496188A 1988-08-22 1988-08-22

Publications (1)

Publication Number Publication Date
ATE106072T1 true ATE106072T1 (de) 1994-06-15

Family

ID=22883487

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89402320T ATE106072T1 (de) 1988-08-22 1989-08-22 Platinkomplexe mit einzelnen isomeren von neoalkylsäuren.

Country Status (9)

Country Link
EP (1) EP0356332B1 (de)
KR (1) KR920003925B1 (de)
AT (1) ATE106072T1 (de)
AU (1) AU4210089A (de)
CA (1) CA1339034C (de)
DE (1) DE68915490T2 (de)
ES (1) ES2052949T3 (de)
IL (1) IL91374A0 (de)
WO (1) WO1990002111A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0994367A (ja) * 1995-09-28 1997-04-08 Tokai Ind Sewing Mach Co Ltd ミシンフレーム
US5843475A (en) * 1996-12-06 1998-12-01 Board Of Regents, The University Of Texas System Delivery and activation through liposome incorporation of diaminocyclohexane platinum (II) complexes
IL131008A (en) * 1997-02-05 2003-06-24 Upjohn Co Lipid complexes and liposomes of highly insoluble platinum complex dicarboxylate
KR100393419B1 (ko) * 2000-02-18 2003-08-02 썬스타 특수정밀 주식회사 실 끊김 발생시 수틀 이송기능을 갖는 자수기 및 수틀이송 방법
EP1293205A1 (de) * 2001-09-18 2003-03-19 G2M Cancer Drugs AG Valproinsäure und deren Derivate zur Kombinationsbehandlung von Krebs beim Menschen und zur Behandlung von Tumor-Metastasen und minimaler Resterkrankung
CA2461187C (en) * 2001-09-21 2010-06-22 Sumitomo Pharmaceuticals Co., Ltd. Lyophilized formulation
AU2003233586A1 (en) * 2003-05-20 2005-01-21 Aronex Pharmaceuticals, Inc. Combination chemotherapy comprising capecitabine and a liposomal platinum complex
EP2208731B1 (de) 2009-06-26 2012-08-15 Umicore AG & Co. KG Verfahren zur Herstellung von 1,2-Diamino-Cyclohexan-Platin(II)-Komplexen

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3441600A (en) * 1966-06-16 1969-04-29 Sinclair Research Inc Liquid esters of neoalkyl polyols and neoalkyl fatty acids
BE755997A (fr) * 1969-09-11 1971-03-10 Bp Chem Int Ltd Production d'acides dicarboxyliques
CA1070289A (en) * 1975-05-19 1980-01-22 Rakhil K. Freidlina Mixtures of poly-branched monocarboxylic acids and process for preparing same
CA1088563A (en) * 1977-03-24 1980-10-28 Anatoli Onopchenko Production of carboxylic acids from olefins and mixtures of olefins
CH624011A5 (de) * 1977-08-05 1981-07-15 Battelle Memorial Institute
JPS5829957B2 (ja) * 1977-09-12 1983-06-25 喜徳 喜谷 新規な白金錯体
SU818654A1 (ru) * 1979-05-07 1981-04-07 Всесоюзный Ордена Трудовогокрасного Знамени Научно-Исследо-Вательский Горнометаллургическийинститут Цветных Металлов "Внии-Цветмет" Вспениватель дл флотации рудцВЕТНыХ МЕТАллОВ
IL63658A0 (en) * 1980-09-03 1981-11-30 Johnson Matthey Plc Co-ordination compound of platinum and its preparation
CA1202946A (en) * 1982-10-13 1986-04-08 Himont Incorporated Method for preparing an improved catalyst support
JPS6296A (ja) * 1985-03-06 1987-01-06 Sumitomo Pharmaceut Co Ltd 脂溶性白金（２）錯体
US5041581A (en) * 1985-10-18 1991-08-20 The University Of Texas System Board Of Regents Hydrophobic cis-platinum complexes efficiently incorporated into liposomes

Also Published As

Publication number Publication date
IL91374A0 (en) 1990-04-29
WO1990002111A1 (en) 1990-03-08
DE68915490D1 (de) 1994-06-30
KR920003925B1 (ko) 1992-05-18
ES2052949T3 (es) 1994-07-16
DE68915490T2 (de) 1995-02-02
AU4210089A (en) 1990-03-23
EP0356332B1 (de) 1994-05-25
EP0356332A3 (en) 1990-08-29
CA1339034C (en) 1997-04-01
KR900701719A (ko) 1990-12-04
EP0356332A2 (de) 1990-02-28

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee