ATE106877T1 - 4,5,6,7-tetrasubstituierte benzoxazolone. - Google Patents

4,5,6,7-tetrasubstituierte benzoxazolone.

Info

Publication number: ATE106877T1
Authority: AT; Austria
Prior art keywords: alkyl; hydrogen; benzoxazolones; het; halo
Prior art date: 1989-07-20

Application number

AT90307618T

Other languages

English (en)

Inventor

Masami Nakane

Takashi Mano

Fumitaka Ito

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-07-20

Filing date

1990-07-12

Publication date

1994-06-15

1990-07-12 Application filed by Pfizer filed Critical Pfizer

1994-06-15 Application granted granted Critical

1994-06-15 Publication of ATE106877T1 publication Critical patent/ATE106877T1/de

Links

125000006273 (C1-C3) alkyl group Chemical group 0.000 abstract 3
229910052739 hydrogen Inorganic materials 0.000 abstract 3
239000001257 hydrogen Substances 0.000 abstract 3
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
150000001875 compounds Chemical class 0.000 abstract 2
125000004455 (C1-C3) alkylthio group Chemical group 0.000 abstract 1
125000006274 (C1-C3)alkoxy group Chemical group 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
125000003282 alkyl amino group Chemical group 0.000 abstract 1
230000000172 allergic effect Effects 0.000 abstract 1
208000010668 atopic eczema Diseases 0.000 abstract 1
125000002541 furyl group Chemical group 0.000 abstract 1
125000001475 halogen functional group Chemical group 0.000 abstract 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
125000002883 imidazolyl group Chemical group 0.000 abstract 1
125000003453 indazolyl group Chemical group N1N=C(C2=C1C=CC=C2)* 0.000 abstract 1
230000004968 inflammatory condition Effects 0.000 abstract 1
125000002971 oxazolyl group Chemical group 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
125000004309 pyranyl group Chemical group O1C(C=CC=C1)* 0.000 abstract 1
125000004076 pyridyl group Chemical group 0.000 abstract 1
125000000168 pyrrolyl group Chemical group 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
125000001544 thienyl group Chemical group 0.000 abstract 1
125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
- C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Pain & Pain Management (AREA)
Diabetes (AREA)
Pulmonology (AREA)
Immunology (AREA)
Hematology (AREA)
Rheumatology (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
Non-Silver Salt Photosensitive Materials And Non-Silver Salt Photography (AREA)

AT90307618T 1989-07-20 1990-07-12 4,5,6,7-tetrasubstituierte benzoxazolone. ATE106877T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP1188683A JPH0678327B2 (ja)	1989-07-20	1989-07-20	４，５，６，７，―四置換ベンゾオキサゾロン類

Publications (1)

Publication Number	Publication Date
ATE106877T1 true ATE106877T1 (de)	1994-06-15

Family

ID=16228012

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT90307618T ATE106877T1 (de)	1989-07-20	1990-07-12	4,5,6,7-tetrasubstituierte benzoxazolone.

Country Status (18)

Country	Link
US (1)	US5071863A (de)
EP (1)	EP0409484B1 (de)
JP (1)	JPH0678327B2 (de)
KR (1)	KR930002099B1 (de)
AT (1)	ATE106877T1 (de)
AU (1)	AU616608B2 (de)
CA (1)	CA2021421A1 (de)
DE (1)	DE69009607T2 (de)
DK (1)	DK0409484T3 (de)
ES (1)	ES2055332T3 (de)
FI (1)	FI95378C (de)
HU (1)	HU206101B (de)
IE (1)	IE63203B1 (de)
IL (1)	IL95085A (de)
NO (1)	NO903230L (de)
NZ (1)	NZ234583A (de)
PT (1)	PT94750A (de)
ZA (1)	ZA905677B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2674524B1 (fr) *	1991-03-25	1993-05-21	Adir	Nouveaux amides alkyl heterocycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
US7794761B2 (en) *	2000-04-13	2010-09-14	Seroctin Research & Technology, Inc.	Methods for inducing anti-anxiety and calming effects in animals and humans
US20040192669A1 (en)	2000-04-13	2004-09-30	Rosenfeld Mark J.	Novel compounds for use in weight loss and appetite suppression in humans
US7524877B2 (en)	2003-11-20	2009-04-28	Seroctin Research & Technology, Inc.	Compounds for use in weight loss and appetite suppression in humans
JP4695012B2 (ja) *	2006-04-21	2011-06-08	セイコークロック株式会社	アラーム時計
BRPI0917540A2 (pt)	2008-08-05	2015-11-17	Daiichi Sankyo Co Ltd	composto, sal farmacologicamente aceitavél, composição farmacêutica, e, uso de um composto ou sal farmacologicamente aceitável

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3256293A (en) *	1964-02-05	1966-06-14	Monsanto Co	3-(phenylcarbamoyl) benzoxazolinones-2
US3657265A (en) *	1968-06-21	1972-04-18	Olin Corp	Process for preparing benzoxazolones from aromatic nitro compounds
IL40346A (en) *	1971-09-28	1975-05-22	Ciba Geigy Ag	Benzoxazolylmethyl-and benzthiazolylmethyl dithiophosphoric acid esters,their manufacture and their use as pesticides
US4227915A (en) *	1978-05-18	1980-10-14	Monsanto Company	N-Substituted oxobenzothiazoline and oxobenzoxazoline derivatives and their use as plant growth regulants
JPS57123103A (en) *	1981-01-26	1982-07-31	Hokko Chem Ind Co Ltd	Agricultural and horticultural fungicide
GB8325370D0 (en) *	1983-09-22	1983-10-26	Fujisawa Pharmaceutical Co	Benzoxazoline and benzothiazoline derivatives
JPS6293283A (ja) *	1985-10-18	1987-04-28	Idemitsu Kosan Co Ltd	ベンゾオキサゾロン誘導体，その製造方法およびそれを有効成分とする農園芸用殺菌剤
DK288287A (da) *	1986-06-09	1987-12-10	Pfizer	Heterocycliske forbindelser samt farmaceutiske praeparater til behandling af allergiske eller inflammatoriske tilstande
US4835166A (en) *	1986-06-09	1989-05-30	Pfizer Inc.	Antiallergy and antiinflammatory agents
IL93473A0 (en) *	1989-02-28	1990-11-29	Pfizer	Antiinflammatory benzoxazolones

1989
- 1989-07-20 JP JP1188683A patent/JPH0678327B2/ja not_active Expired - Lifetime
1990
- 1990-07-12 DE DE69009607T patent/DE69009607T2/de not_active Expired - Fee Related
- 1990-07-12 ES ES90307618T patent/ES2055332T3/es not_active Expired - Lifetime
- 1990-07-12 DK DK90307618.0T patent/DK0409484T3/da active
- 1990-07-12 EP EP90307618A patent/EP0409484B1/de not_active Expired - Lifetime
- 1990-07-12 AT AT90307618T patent/ATE106877T1/de active
- 1990-07-13 IL IL9508590A patent/IL95085A/en not_active IP Right Cessation
- 1990-07-18 PT PT94750A patent/PT94750A/pt not_active Application Discontinuation
- 1990-07-18 US US07/554,625 patent/US5071863A/en not_active Expired - Fee Related
- 1990-07-18 CA CA002021421A patent/CA2021421A1/en not_active Abandoned
- 1990-07-19 NZ NZ234583A patent/NZ234583A/en unknown
- 1990-07-19 FI FI903655A patent/FI95378C/fi not_active IP Right Cessation
- 1990-07-19 KR KR1019900010969A patent/KR930002099B1/ko not_active Expired - Fee Related
- 1990-07-19 ZA ZA905677A patent/ZA905677B/xx unknown
- 1990-07-19 IE IE263090A patent/IE63203B1/en not_active IP Right Cessation
- 1990-07-19 NO NO90903230A patent/NO903230L/no unknown
- 1990-07-20 AU AU59193/90A patent/AU616608B2/en not_active Ceased
- 1990-07-20 HU HU904565A patent/HU206101B/hu not_active IP Right Cessation

Also Published As

Publication number	Publication date
AU5919390A (en)	1991-01-24
IL95085A0 (en)	1991-06-10
HU206101B (en)	1992-08-28
DE69009607D1 (de)	1994-07-14
ES2055332T3 (es)	1994-08-16
NO903230D0 (no)	1990-07-19
NO903230L (no)	1991-01-21
DE69009607T2 (de)	1994-09-22
EP0409484A3 (en)	1991-05-15
NZ234583A (en)	1991-12-23
KR930002099B1 (ko)	1993-03-26
FI95378C (fi)	1996-01-25
KR910002818A (ko)	1991-02-26
EP0409484B1 (de)	1994-06-08
EP0409484A2 (de)	1991-01-23
JPH0352875A (ja)	1991-03-07
HUT57745A (en)	1991-12-30
DK0409484T3 (da)	1994-07-04
US5071863A (en)	1991-12-10
IL95085A (en)	1994-10-21
AU616608B2 (en)	1991-10-31
IE63203B1 (en)	1995-04-05
JPH0678327B2 (ja)	1994-10-05
FI903655A0 (fi)	1990-07-19
IE902630A1 (en)	1991-02-27
HU904565D0 (en)	1990-12-28
PT94750A (pt)	1991-03-20
FI95378B (fi)	1995-10-13
CA2021421A1 (en)	1991-01-21
ZA905677B (en)	1992-02-26

Publication	Publication Date	Title
DE50311967D1 (de)	2009-11-12	3-heteroarylsubstituierte 5-methyloxymethyl-isoxazoline als herbizide
ID17851A (id)	1998-01-29	Persenyawaan heterosiklis, produksi dan pemakaiannya
ATE270103T1 (de)	2004-07-15	Aminophenoxyessigsäure derivate als neuroschützende mittel
SE0201937D0 (sv)	2002-06-20	Therapeutic agents
NO873650D0 (no)	1987-08-28	Dihydropyridinderivater.
FI922341A0 (fi)	1992-05-22	Piperidin- och pyrrolidinderivat.
ATE106877T1 (de)	1994-06-15	4,5,6,7-tetrasubstituierte benzoxazolone.
DE60201921D1 (de)	2004-12-23	Kondensierte Pyrazolverbindungen
DE69120603D1 (de)	1996-08-08	Isochromanderivate
FI902291A0 (fi)	1990-05-08	Heterocykliska guanider som 5ht3 -antagonister.
JPS6429367A (en)	1989-01-31	2-amino-5-hydroxy-4-pyrimidone
GB0412893D0 (en)	2004-07-14	Novel antiviral macrocycle derivatives and metal complexes, incorporating bridged macrocycles
TW337983B (en)	1998-08-11	1, 3-oxazn-4-one derivatives, their preparation and uses
ATE110367T1 (de)	1994-09-15	Kalziumantagonisten.
ES2055476T3 (es)	1994-08-16	Compuestos del tiocarbamoilacetonitrilo.
DE69218718D1 (de)	1997-05-07	Pharmazeutische Zusammensetzungen die Triazole Derivate enthalten zur rektalen Verabbrechung