ATE108833T1 - Antikörper gegen fibrin, immunogene peptide für die herstellung dieser antikörper, verfahren zur bestimmung von fibrin und pharmazeutische zubereitungen auf der basis dieser antikörper. - Google Patents

Antikörper gegen fibrin, immunogene peptide für die herstellung dieser antikörper, verfahren zur bestimmung von fibrin und pharmazeutische zubereitungen auf der basis dieser antikörper.

Info

Publication number
ATE108833T1
ATE108833T1 AT90201065T AT90201065T ATE108833T1 AT E108833 T1 ATE108833 T1 AT E108833T1 AT 90201065 T AT90201065 T AT 90201065T AT 90201065 T AT90201065 T AT 90201065T AT E108833 T1 ATE108833 T1 AT E108833T1
Authority
AT
Austria
Prior art keywords
antibodies
fibrin
determination
production
methods
Prior art date
Application number
AT90201065T
Other languages
English (en)
Inventor
Willem Nieuwenhuizen
Original Assignee
Tno
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tno filed Critical Tno
Application granted granted Critical
Publication of ATE108833T1 publication Critical patent/ATE108833T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/36—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood coagulation factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
    • A61K47/6845—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a cytokine, e.g. growth factors, VEGF, TNF, a lymphokine or an interferon
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AT90201065T 1989-05-01 1990-04-26 Antikörper gegen fibrin, immunogene peptide für die herstellung dieser antikörper, verfahren zur bestimmung von fibrin und pharmazeutische zubereitungen auf der basis dieser antikörper. ATE108833T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL8901102A NL8901102A (nl) 1989-05-01 1989-05-01 Antilichamen tegen fibrine; voor de bereiding van de antilichamen geschikte immunogene peptiden, werkwijze voor het bepalen van fibrine en farmaceutisch preparaat op basis van de antilichamen.

Publications (1)

Publication Number Publication Date
ATE108833T1 true ATE108833T1 (de) 1994-08-15

Family

ID=19854590

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90201065T ATE108833T1 (de) 1989-05-01 1990-04-26 Antikörper gegen fibrin, immunogene peptide für die herstellung dieser antikörper, verfahren zur bestimmung von fibrin und pharmazeutische zubereitungen auf der basis dieser antikörper.

Country Status (8)

Country Link
US (1) US5124439A (de)
EP (1) EP0396188B1 (de)
JP (1) JP2634683B2 (de)
AT (1) ATE108833T1 (de)
DE (1) DE69010750T2 (de)
DK (1) DK0396188T3 (de)
ES (1) ES2060927T3 (de)
NL (1) NL8901102A (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0668875A4 (de) * 1992-10-12 1999-05-26 Agen Ltd Auf blutgerinnsel gerichtetes antikoagulanz, verfahren zur herstellung desselben und zu seiner verwendung.
ES2300102T3 (es) * 1993-11-02 2008-06-01 Mitsubishi Kagaku Iatron, Inc. Anticuerpos anti-fibrina soluble humana, hibridoma que los produce y procedimiento de inmunoensayo.
AU709134B2 (en) * 1994-05-02 1999-08-19 E.R. Squibb & Sons, Inc. Recombinant fibrin chains, fibrin and fibrin-homologs
DE19729591A1 (de) * 1997-07-10 1999-02-11 Therasorb Medizinische Systeme Mittel zur Behandlung und/oder Prophylaxe von Mikrozirkulationsstörungen
US9814672B2 (en) 2007-03-09 2017-11-14 Susan T. Laing Echogenic vehicle for clinical delivery of plasminogen activator and other fibrin-binding therapeutics to thrombi

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4916070A (en) * 1986-04-14 1990-04-10 The General Hospital Corporation Fibrin-specific antibodies and method of screening for the antibodies
DE3701812A1 (de) * 1987-01-22 1988-08-04 Max Planck Gesellschaft Fibrinspezifischer antikoerper, verfahren zur seiner herstellung und seine verwendung

Also Published As

Publication number Publication date
EP0396188A1 (de) 1990-11-07
JPH0348159A (ja) 1991-03-01
NL8901102A (nl) 1990-12-03
EP0396188B1 (de) 1994-07-20
DE69010750D1 (de) 1994-08-25
DK0396188T3 (da) 1994-08-22
DE69010750T2 (de) 1994-12-22
US5124439A (en) 1992-06-23
ES2060927T3 (es) 1994-12-01
JP2634683B2 (ja) 1997-07-30

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee