|
US5225538A
(en)
*
|
1989-02-23 |
1993-07-06 |
Genentech, Inc. |
Lymphocyte homing receptor/immunoglobulin fusion proteins
|
|
US5116964A
(en)
*
|
1989-02-23 |
1992-05-26 |
Genentech, Inc. |
Hybrid immunoglobulins
|
|
US6406697B1
(en)
|
1989-02-23 |
2002-06-18 |
Genentech, Inc. |
Hybrid immunoglobulins
|
|
EP0428266B1
(de)
*
|
1989-10-13 |
1994-09-28 |
Takara Shuzo Co. Ltd. |
Antikrebsmittel
|
|
US5629287A
(en)
*
|
1991-01-18 |
1997-05-13 |
University College London |
Depot formulations
|
|
US5610148A
(en)
*
|
1991-01-18 |
1997-03-11 |
University College London |
Macroscopically oriented cell adhesion protein for wound treatment
|
|
FR2686899B1
(fr)
|
1992-01-31 |
1995-09-01 |
Rhone Poulenc Rorer Sa |
Nouveaux polypeptides biologiquement actifs, leur preparation et compositions pharmaceutiques les contenant.
|
|
FR2719593B1
(fr)
*
|
1994-05-06 |
1996-05-31 |
Rhone Poulenc Rorer Sa |
Nouveaux polypeptides biologiquement actifs, leur préparation et composition pharmaceutique les contenant.
|
|
US7112320B1
(en)
|
1995-06-07 |
2006-09-26 |
Andre Beaulieu |
Solid wound healing formulations containing fibronectin
|
|
US5641483A
(en)
*
|
1995-06-07 |
1997-06-24 |
Beaulieu; Andre |
Wound healing formulations containing human plasma fibronectin
|
|
US5877149A
(en)
|
1995-06-07 |
1999-03-02 |
Beaulieu; Andre |
Deepithelialized skin diffusion cell system
|
|
US6528483B2
(en)
|
1995-06-07 |
2003-03-04 |
André Beaulieu |
Method of producing concentrated non-buffered solutions of fibronectin
|
|
JP3192067B2
(ja)
*
|
1995-10-09 |
2001-07-23 |
科学技術振興事業団 |
ペプチドとコラーゲン収縮阻害剤
|
|
GB9526733D0
(en)
|
1995-12-30 |
1996-02-28 |
Delta Biotechnology Ltd |
Fusion proteins
|
|
US5922676A
(en)
*
|
1996-09-20 |
1999-07-13 |
The Burnham Institute |
Methods of inhibiting cancer by using superfibronectin
|
|
EP2213743A1
(de)
|
2000-04-12 |
2010-08-04 |
Human Genome Sciences, Inc. |
Albuminfusionsproteine
|
|
US6946134B1
(en)
|
2000-04-12 |
2005-09-20 |
Human Genome Sciences, Inc. |
Albumin fusion proteins
|
|
CA2420593A1
(en)
*
|
2000-08-25 |
2002-03-07 |
Human Genome Sciences, Inc. |
Tumor necrosis factor receptors 6.alpha. and 6.beta.
|
|
IL155812A0
(en)
|
2000-12-07 |
2003-12-23 |
Lilly Co Eli |
Glp-1 fusion proteins
|
|
US7507413B2
(en)
|
2001-04-12 |
2009-03-24 |
Human Genome Sciences, Inc. |
Albumin fusion proteins
|
|
AU2002364586A1
(en)
|
2001-12-21 |
2003-07-30 |
Delta Biotechnology Limited |
Albumin fusion proteins
|
|
WO2005003296A2
(en)
|
2003-01-22 |
2005-01-13 |
Human Genome Sciences, Inc. |
Albumin fusion proteins
|
|
US20060002935A1
(en)
|
2002-06-28 |
2006-01-05 |
Domantis Limited |
Tumor Necrosis Factor Receptor 1 antagonists and methods of use therefor
|
|
GB0217033D0
(en)
|
2002-07-23 |
2002-08-28 |
Delta Biotechnology Ltd |
Gene and polypeptide sequences
|
|
EP2371390A3
(de)
|
2004-10-08 |
2013-03-13 |
Domantis Limited |
Antagonisten und Verwendungsverfahren dafür
|
|
WO2007142667A2
(en)
|
2005-10-13 |
2007-12-13 |
Human Genome Sciences, Inc. |
Treatment of patients with autoantibody positive disease
|
|
CN103071209A
(zh)
|
2005-11-17 |
2013-05-01 |
周吉尼克斯股份有限公司 |
用无针注射递送粘稠制剂
|
|
EP1816201A1
(de)
|
2006-02-06 |
2007-08-08 |
CSL Behring GmbH |
Modifizierter Koagulationsfaktor VIIa mit verbesserter 'half-life'-Stabiltät
|
|
US8268347B1
(en)
|
2006-10-24 |
2012-09-18 |
Aradigm Corporation |
Dual action, inhaled formulations providing both an immediate and sustained release profile
|
|
US8114630B2
(en)
|
2007-05-02 |
2012-02-14 |
Ambrx, Inc. |
Modified interferon beta polypeptides and their uses
|
|
CA2688433A1
(en)
|
2007-06-06 |
2008-12-11 |
Domantis Limited |
Methods for selecting protease resistant polypeptides
|
|
MX2010005317A
(es)
|
2007-11-20 |
2010-06-02 |
Ambrx Inc |
Polipeptidos de insulina modificados y sus usos.
|
|
ES2563061T3
(es)
|
2008-04-28 |
2016-03-10 |
Zogenix, Inc. |
Nuevas formulaciones para el tratamiento de la migraña
|
|
EA201001734A1
(ru)
|
2008-05-02 |
2011-10-31 |
Новартис Аг |
Улучшенные связывающие молекулы на основе фибронектина и их применение
|
|
CN102159230A
(zh)
|
2008-07-23 |
2011-08-17 |
Ambrx公司 |
经修饰的牛g-csf多肽和其用途
|
|
WO2010059315A1
(en)
|
2008-11-18 |
2010-05-27 |
Merrimack Pharmaceuticals, Inc. |
Human serum albumin linkers and conjugates thereof
|
|
EP2364326B1
(de)
|
2008-12-05 |
2018-07-04 |
Glaxo Group Limited |
Verfahren zur selektion proteaseresistenter polypeptide
|
|
AU2010215479B2
(en)
|
2009-02-19 |
2015-01-22 |
Glaxo Group Limited |
Improved anti-TNFR1 polypeptides, antibody variable domains & antagonists
|
|
US11512326B2
(en)
|
2009-05-26 |
2022-11-29 |
University Of Florida Research Foundation, Incorporated |
Small angiotensin peptide expression system in mammalian cells
|
|
JP2012532619A
(ja)
|
2009-07-16 |
2012-12-20 |
グラクソ グループ リミテッド |
Tnfr1を部分的に阻害するためのアンタゴニスト、用途および方法
|
|
JP2013507978A
(ja)
|
2009-10-27 |
2013-03-07 |
グラクソ グループ リミテッド |
安定な抗tnfr1ポリペプチド、抗体可変ドメイン及びアンタゴニスト
|
|
WO2011051466A1
(en)
|
2009-11-02 |
2011-05-05 |
Novartis Ag |
Anti-idiotypic fibronectin-based binding molecules and uses thereof
|
|
BR112012015597A2
(pt)
|
2009-12-21 |
2017-01-31 |
Ambrx Inc |
peptídeos de somatotropina suínos modificados e seus usos
|
|
MX349301B
(es)
|
2009-12-21 |
2017-07-21 |
Ambrx Inc |
Polipéptidos de somatotropina bovina modificados y sus usos.
|
|
WO2011092233A1
(en)
|
2010-01-29 |
2011-08-04 |
Novartis Ag |
Yeast mating to produce high-affinity combinations of fibronectin-based binders
|
|
EP2566892B1
(de)
|
2010-05-06 |
2017-12-20 |
Novartis AG |
Zusammensetzungen und verfahren zur verwendung von therapeutischen antikörpern gegen ldl-assoziiertes protein 6 (lrp6)
|
|
PL3552619T3
(pl)
|
2010-07-09 |
2025-12-01 |
Bioverativ Therapeutics Inc. |
Polipeptydy czynnika ix i sposoby ich zastosowania
|
|
EA030886B1
(ru)
|
2010-08-17 |
2018-10-31 |
Амбркс, Инк. |
Модифицированные полипептиды релаксина, содержащие некодируемую в природе аминокислоту, связанную с полимером, и их применение
|
|
AU2011290672B2
(en)
|
2010-08-20 |
2015-07-09 |
Novartis Ag |
Antibodies for epidermal growth factor receptor 3 (HER3)
|
|
WO2012048276A2
(en)
|
2010-10-08 |
2012-04-12 |
Caridianbct, Inc. |
Customizable methods and systems of growing and harvesting cells in a hollow fiber bioreactor system
|
|
WO2012069466A1
(en)
|
2010-11-24 |
2012-05-31 |
Novartis Ag |
Multispecific molecules
|
|
RU2014103288A
(ru)
|
2011-07-01 |
2015-08-10 |
Байер Интеллектчуал Проперти Гмбх |
Слитые полипептиды релаксина и их применение
|
|
KR20140039257A
(ko)
|
2011-07-08 |
2014-04-01 |
바이엘 인텔렉쳐 프로퍼티 게엠베하 |
릴랙신을 방출하는 융합 단백질 및 이의 용도
|
|
ES2666856T3
(es)
|
2011-11-04 |
2018-05-08 |
Novartis Ag |
Proteína 6 relacionada con lipoproteínas de baja densidad (LRP6) - constructos extensores de la vida media
|
|
CN104105709A
(zh)
|
2011-12-05 |
2014-10-15 |
诺华股份有限公司 |
抗her3的结构域ii的表皮生长因子受体3(her3)抗体
|
|
EP3590538A1
(de)
|
2011-12-05 |
2020-01-08 |
Novartis AG |
Antikörper für den epidermalen wachstumsfaktorrezeptor 3 (her 3)
|
|
EP2851429B1
(de)
|
2012-05-18 |
2019-07-24 |
Adda Biotech Inc. |
Protein und proteinkonjugate zur behandlung von diabetes und anwendungen davon
|
|
WO2014036520A1
(en)
|
2012-08-30 |
2014-03-06 |
Merrimack Pharmaceuticals, Inc. |
Combination therapies comprising anti-erbb3 agents
|
|
WO2014164703A1
(en)
|
2013-03-11 |
2014-10-09 |
University Of Florida Research Foundation, Inc. |
Delivery of card protein as therapy for occular inflammation
|
|
EP3611189A1
(de)
|
2013-03-14 |
2020-02-19 |
Novartis AG |
Antikörper gegen notch 3
|
|
WO2015073913A1
(en)
|
2013-11-16 |
2015-05-21 |
Terumo Bct, Inc. |
Expanding cells in a bioreactor
|
|
US10626156B2
(en)
|
2013-12-06 |
2020-04-21 |
Jie Han |
Bioreversable promoieties for nitrogen-containing and hydroxyl-containing drugs
|
|
WO2015148704A1
(en)
|
2014-03-25 |
2015-10-01 |
Terumo Bct, Inc. |
Passive replacement of media
|
|
EP3157947A1
(de)
|
2014-06-23 |
2017-04-26 |
Novartis AG |
Hsa-gdf-15-fusionspolypeptid und verwendung davon
|
|
EP3198006B1
(de)
|
2014-09-26 |
2021-03-24 |
Terumo BCT, Inc. |
Geplante fütterung
|
|
EP4414028A3
(de)
|
2015-05-19 |
2024-11-27 |
Yale University |
Zusammensetzungen zur behandlung pathologischer calcifizierungserkrankungen und verfahren mit verwendung davon
|
|
WO2017004592A1
(en)
|
2015-07-02 |
2017-01-05 |
Terumo Bct, Inc. |
Cell growth with mechanical stimuli
|
|
JP6946304B2
(ja)
|
2015-12-22 |
2021-10-06 |
ノバルティス アーゲー |
増殖分化因子15(gdf−15)を使用して代謝障害を処置するまたは軽快させる方法
|
|
MA55746A
(fr)
|
2016-01-21 |
2022-03-02 |
Novartis Ag |
Molécules multispécifiques ciblant cll-1
|
|
US11965175B2
(en)
|
2016-05-25 |
2024-04-23 |
Terumo Bct, Inc. |
Cell expansion
|
|
US11104874B2
(en)
|
2016-06-07 |
2021-08-31 |
Terumo Bct, Inc. |
Coating a bioreactor
|
|
US11685883B2
(en)
|
2016-06-07 |
2023-06-27 |
Terumo Bct, Inc. |
Methods and systems for coating a cell growth surface
|
|
US12234441B2
(en)
|
2017-03-31 |
2025-02-25 |
Terumo Bct, Inc. |
Cell expansion
|
|
CN117247899A
(zh)
|
2017-03-31 |
2023-12-19 |
泰尔茂比司特公司 |
细胞扩增
|
|
US11624046B2
(en)
|
2017-03-31 |
2023-04-11 |
Terumo Bct, Inc. |
Cell expansion
|
|
KR102870868B1
(ko)
|
2018-06-01 |
2025-10-15 |
노파르티스 아게 |
Bcma에 대한 결합 분자 및 이의 용도
|
|
EP3887393A1
(de)
|
2018-11-26 |
2021-10-06 |
Novartis AG |
Lpl-gpihbp1 fusionspolypeptide
|
|
US20220098252A1
(en)
|
2019-01-25 |
2022-03-31 |
Ospedale San Raffaele S.R.L. |
Inhibitor of dux4 and uses thereof
|
|
JP7489407B2
(ja)
|
2019-05-21 |
2024-05-23 |
ノバルティス アーゲー |
Cd19結合分子及びその使用
|
|
US12037378B2
(en)
|
2019-05-21 |
2024-07-16 |
Novartis Ag |
Variant CD58 domains and uses thereof
|
|
MX2022002638A
(es)
|
2019-09-06 |
2022-03-25 |
Novartis Ag |
Proteinas de fusion terapeuticas.
|
|
CA3199095A1
(en)
|
2020-11-06 |
2022-05-12 |
Novartis Ag |
Cd19 binding molecules and uses thereof
|
|
EP4314244B1
(de)
|
2021-03-23 |
2025-07-23 |
Terumo BCT, Inc. |
Zellerfassung und -erweiterung
|
|
US12209689B2
(en)
|
2022-02-28 |
2025-01-28 |
Terumo Kabushiki Kaisha |
Multiple-tube pinch valve assembly
|
|
IL316174A
(en)
|
2022-04-26 |
2024-12-01 |
Novartis Ag |
Multiple specific antibodies targeting IL-13 and IL-18
|
|
USD1099116S1
(en)
|
2022-09-01 |
2025-10-21 |
Terumo Bct, Inc. |
Display screen or portion thereof with a graphical user interface for displaying cell culture process steps and measurements of an associated bioreactor device
|
|
EP4389762A1
(de)
|
2022-12-23 |
2024-06-26 |
Ospedale San Raffaele S.r.l. |
Inhibitoren der dux4-aktivität und ihre therapeutische verwendung.
|
|
CN116574173B
(zh)
*
|
2023-06-25 |
2026-04-17 |
浙江诸暨聚源生物技术有限公司 |
蛋白稳定性增强的重组人源纤连蛋白突变体及其表达菌株
|
|
WO2026058155A1
(en)
|
2024-09-11 |
2026-03-19 |
Novartis Ag |
Antibodies targeting il-31
|