ATE109023T1 - Mikrokugeln aus denen wasserlösliche materialien mit vorbestimmter geschwindigkeit freigesetzt werden, und verfahren zur herstellung derselben. - Google Patents

Mikrokugeln aus denen wasserlösliche materialien mit vorbestimmter geschwindigkeit freigesetzt werden, und verfahren zur herstellung derselben.

Info

Publication number
ATE109023T1
ATE109023T1 AT91903868T AT91903868T ATE109023T1 AT E109023 T1 ATE109023 T1 AT E109023T1 AT 91903868 T AT91903868 T AT 91903868T AT 91903868 T AT91903868 T AT 91903868T AT E109023 T1 ATE109023 T1 AT E109023T1
Authority
AT
Austria
Prior art keywords
water
polymer
miscible
substance
microballs
Prior art date
Application number
AT91903868T
Other languages
English (en)
Inventor
Henri Wantier
Fabienne Mathieu
Marc Baudrihaye
Dominique Delacroix
Original Assignee
Teva Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teva Pharma filed Critical Teva Pharma
Application granted granted Critical
Publication of ATE109023T1 publication Critical patent/ATE109023T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/06—Making microcapsules or microballoons by phase separation
    • B01J13/12—Making microcapsules or microballoons by phase separation removing solvent from the wall-forming material solution
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/06—Making microcapsules or microballoons by phase separation
    • B01J13/12—Making microcapsules or microballoons by phase separation removing solvent from the wall-forming material solution
    • B01J13/125—Making microcapsules or microballoons by phase separation removing solvent from the wall-forming material solution by evaporation of the solvent

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Detergent Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
AT91903868T 1990-02-22 1991-02-18 Mikrokugeln aus denen wasserlösliche materialien mit vorbestimmter geschwindigkeit freigesetzt werden, und verfahren zur herstellung derselben. ATE109023T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR909002189A FR2658432B1 (fr) 1990-02-22 1990-02-22 Microspheres pour la liberation controlee des substances hydrosolubles et procede de preparation.

Publications (1)

Publication Number Publication Date
ATE109023T1 true ATE109023T1 (de) 1994-08-15

Family

ID=9394021

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91903868T ATE109023T1 (de) 1990-02-22 1991-02-18 Mikrokugeln aus denen wasserlösliche materialien mit vorbestimmter geschwindigkeit freigesetzt werden, und verfahren zur herstellung derselben.

Country Status (7)

Country Link
EP (1) EP0469110B1 (de)
JP (1) JP3512408B2 (de)
AT (1) ATE109023T1 (de)
CA (1) CA2053913C (de)
DE (1) DE69103104T2 (de)
FR (1) FR2658432B1 (de)
WO (1) WO1991012882A1 (de)

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Also Published As

Publication number Publication date
EP0469110A1 (de) 1992-02-05
WO1991012882A1 (fr) 1991-09-05
CA2053913C (fr) 2001-04-03
DE69103104D1 (de) 1994-09-01
DE69103104T2 (de) 1995-01-05
EP0469110B1 (de) 1994-07-27
CA2053913A1 (fr) 1991-08-23
FR2658432A1 (fr) 1991-08-23
JP3512408B2 (ja) 2004-03-29
FR2658432B1 (fr) 1994-07-01
JPH04505420A (ja) 1992-09-24

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