ATE109157T1 - Fluor enthaltende renin-inhibitoren. - Google Patents

Fluor enthaltende renin-inhibitoren.

Info

Publication number
ATE109157T1
ATE109157T1 AT88305846T AT88305846T ATE109157T1 AT E109157 T1 ATE109157 T1 AT E109157T1 AT 88305846 T AT88305846 T AT 88305846T AT 88305846 T AT88305846 T AT 88305846T AT E109157 T1 ATE109157 T1 AT E109157T1
Authority
AT
Austria
Prior art keywords
renin inhibitors
fluorine
chem
containing renin
cf2conhch3
Prior art date
Application number
AT88305846T
Other languages
English (en)
Inventor
Dennis Jay Hoover
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of ATE109157T1 publication Critical patent/ATE109157T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0227—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the (partial) peptide sequence -Phe-His-NH-(X)2-C(=0)-, e.g. Renin-inhibitors with n = 2 - 6; for n > 6 see C07K5/06 - C07K5/10
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06191—Dipeptides containing heteroatoms different from O, S, or N
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT88305846T 1987-07-01 1988-06-24 Fluor enthaltende renin-inhibitoren. ATE109157T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US6898987A 1987-07-01 1987-07-01

Publications (1)

Publication Number Publication Date
ATE109157T1 true ATE109157T1 (de) 1994-08-15

Family

ID=22085994

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88305846T ATE109157T1 (de) 1987-07-01 1988-06-24 Fluor enthaltende renin-inhibitoren.

Country Status (9)

Country Link
EP (1) EP0297815B1 (de)
JP (1) JPH0757759B2 (de)
AT (1) ATE109157T1 (de)
CA (1) CA1322075C (de)
DE (1) DE3850818T2 (de)
DK (1) DK362688A (de)
ES (1) ES2056930T3 (de)
FI (1) FI883134A7 (de)
PT (1) PT87867B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8619182D0 (en) * 1986-08-06 1986-09-17 Sandoz Ltd Peptides & derivatives
EP0369391A3 (de) * 1988-11-15 1991-09-25 Boehringer Ingelheim Pharmaceuticals Inc. N-substituierte Amide
DE4126485A1 (de) * 1991-08-10 1993-02-11 Bayer Ag Trifluormethyl-haltige pseudopeptide
JP2005259307A (ja) * 2004-03-15 2005-09-22 Sony Corp 光ピックアップ及びディスクドライブ装置
CN101316872B (zh) 2005-11-24 2011-11-30 旭化成化学株式会社 甲基丙烯酸树脂及其制造方法
US8617708B2 (en) 2009-10-22 2013-12-31 Asahi Kasei Chemicals Corporation Methacrylic resin, molded article thereof, and method for producing methacrylic resin

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3674131D1 (de) * 1985-04-19 1990-10-18 Upjohn Co Substituierte dihalo-statin-reninhemmungsmittel.
DE3538749A1 (de) * 1985-10-31 1987-05-07 Merck Patent Gmbh Peptide

Also Published As

Publication number Publication date
EP0297815A3 (en) 1990-06-06
CA1322075C (en) 1993-09-07
DE3850818T2 (de) 1994-11-17
PT87867B (pt) 1995-05-04
ES2056930T3 (es) 1994-10-16
FI883134L (fi) 1989-01-02
JPH0757759B2 (ja) 1995-06-21
DE3850818D1 (de) 1994-09-01
EP0297815A2 (de) 1989-01-04
EP0297815B1 (de) 1994-07-27
PT87867A (pt) 1989-06-30
JPS6422865A (en) 1989-01-25
FI883134A0 (fi) 1988-06-30
DK362688D0 (da) 1988-06-30
DK362688A (da) 1989-02-14
FI883134A7 (fi) 1989-01-02

Similar Documents

Publication Publication Date Title
NO2006018I1 (no) Entekavir:(2-amino-1,9-dihydro-9Ä(1S,3R,4S)-4hydroksy-3-(hydroksymetyl)-2-metylencyklopentylÜ-6H-purin-6-on og hydrater derav, saerlig monohydrat
ES2101960T3 (es) Lactamas benzo-condensadas.
AU694417B2 (en) Cyclic ureas and analogues useful as retroviral protease inhibitiors
EP0629627A3 (de) Bicyclische Carbonsäuren und deren Derivate als NEP und ACA Inhibitoren.
FI904327A0 (fi) N-substituerad-4-pyrimidinaminer och -pyrimidindiaminer, foerfarande foer deras framstaellning och deras anvaendning som laekemedel.
ATE108187T1 (de) Protease-hemmer.
NO175256C (no) Analogifremgangsmåte til fremstilling av terapeutisk aktive 4-oksokinolin-3-karboksylsyrederivater
NO933376D0 (no) Morfinan-derivater og medisinsk anvendelse derav
DE69332616D1 (de) Hemmer der retroviralen Protease
NO174549C (no) Analogifremgangsmåte for fremstilling av terapeutisk aktive, asymmetrisk substituerte, heterocykliske forbindelser
NO173867C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive benzamider
NO931166L (no) Piperdinderivater, deres fremstilling og anvendelse for terapi
NO902555D0 (no) N-heteroaryl-purin-6-aminer og fremgangsmaate for fremstilling derav.
DE3850818D1 (de) Fluor enthaltende Renin-Inhibitoren.
KR900014388A (ko) 에세롤린의 카보네이트 유도체, 이의 제조방법 및 약제로서의 용도
ES2034324T3 (es) Procedimiento de sintesis industrial de alfa amino diacidos n alquilados o de esteres de ellos.
ES2150613T3 (es) Compuestos benzo-condensados de acepinona y piperidinona, utiles como inhibidores de ace y nep.
DK361587D0 (da) Thiazolyleddikesyrederivater og fremgangsmaader til fremstilling deraf
SE7709913L (sv) Sett att framstella penta peptider
ATE204880T1 (de) N-acyldipeptide, und pharmazeutische präparate davon
ATE75472T1 (de) Ergolinylheterocyclen.
DE69405999D1 (de) Pharmazeutisch wirksame enantiomere
GB2013689A (en) Enkephalin analogues
KR900000363A (ko) 1-카바(데티아)세팔로스포린용 중간생성물
ATE36536T1 (de) Phosphoroimidate.

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee