ATE109357T1 - Transdermales estradiol als therapeutisches sytem. - Google Patents
Transdermales estradiol als therapeutisches sytem.Info
- Publication number
- ATE109357T1 ATE109357T1 AT89903563T AT89903563T ATE109357T1 AT E109357 T1 ATE109357 T1 AT E109357T1 AT 89903563 T AT89903563 T AT 89903563T AT 89903563 T AT89903563 T AT 89903563T AT E109357 T1 ATE109357 T1 AT E109357T1
- Authority
- AT
- Austria
- Prior art keywords
- pressure
- estradiol
- sheet material
- sensitive adhesive
- therapeutic system
- Prior art date
Links
- VOXZDWNPVJITMN-ZBRFXRBCSA-N 17β-estradiol Chemical compound OC1=CC=C2[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CCC2=C1 VOXZDWNPVJITMN-ZBRFXRBCSA-N 0.000 title abstract 4
- 229960005309 estradiol Drugs 0.000 title abstract 4
- 229930182833 estradiol Natural products 0.000 title abstract 4
- 230000001225 therapeutic effect Effects 0.000 title 1
- 239000004820 Pressure-sensitive adhesive Substances 0.000 abstract 4
- 239000000463 material Substances 0.000 abstract 4
- 239000010410 layer Substances 0.000 abstract 2
- 239000000853 adhesive Substances 0.000 abstract 1
- 230000001070 adhesive effect Effects 0.000 abstract 1
- 230000007812 deficiency Effects 0.000 abstract 1
- 239000004615 ingredient Substances 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
- 230000009885 systemic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
- A61K9/7061—Polyacrylates
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16063588A | 1988-02-26 | 1988-02-26 | |
| CA000594966A CA1338819C (en) | 1988-02-26 | 1989-03-29 | Transdermal estradiol delivery system |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE109357T1 true ATE109357T1 (de) | 1994-08-15 |
Family
ID=25672560
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT89903563T ATE109357T1 (de) | 1988-02-26 | 1989-02-27 | Transdermales estradiol als therapeutisches sytem. |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0402407B1 (de) |
| JP (1) | JP2931002B2 (de) |
| AT (1) | ATE109357T1 (de) |
| AU (2) | AU630347B2 (de) |
| CA (1) | CA1338819C (de) |
| DE (1) | DE68917292T2 (de) |
| LU (1) | LU88849I2 (de) |
| NL (1) | NL970007I1 (de) |
| WO (1) | WO1989007951A1 (de) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0364211B1 (de) * | 1988-10-11 | 1994-12-21 | Shire Holdings Ltd. | Arzneimittelpräparat für perkutane Absorption |
| US5232703A (en) * | 1989-07-21 | 1993-08-03 | Izhak Blank | Estradiol compositions and methods for topical application |
| DE69007886T2 (de) * | 1989-07-21 | 1994-11-17 | Izhak Blank | Östradiol enthaltende Mittel und Verfahren zur topischen Anwendung. |
| CA2065311C (en) * | 1989-09-08 | 2000-01-11 | Chia-Ming Chiang | Solid matrix system for transdermal drug delivery |
| US5252334A (en) * | 1989-09-08 | 1993-10-12 | Cygnus Therapeutic Systems | Solid matrix system for transdermal drug delivery |
| JP3273430B2 (ja) * | 1989-12-28 | 2002-04-08 | 日東電工株式会社 | エストロゲン含有ゲル製剤 |
| GB9021674D0 (en) * | 1990-10-05 | 1990-11-21 | Ethical Pharma Ltd | Transdermal device |
| TW218849B (de) * | 1991-05-17 | 1994-01-11 | Bristol Myers Squibb Co | |
| US5705185A (en) * | 1991-09-25 | 1998-01-06 | Beta Pharmaceuticals Co. | Transdermal delivery of estradiol and process for manufacturing said device |
| US5518734A (en) * | 1991-09-25 | 1996-05-21 | Beta Pharmaceuticals Co. | Transdermal delivery system for estradiol and process for manufacturing said device |
| US5276079A (en) * | 1991-11-15 | 1994-01-04 | Minnesota Mining And Manufacturing Company | Pressure-sensitive poly(n-vinyl lactam) adhesive composition and method for producing and using same |
| IT1253265B (it) * | 1991-11-25 | 1995-07-14 | Rotta Research Lab | Preparato a matrice copolimerica adesiva a base acrilica per il rilascio transdermico dell'estradiolo. |
| FR2691361B1 (fr) * | 1992-05-19 | 1994-07-08 | Adir | Systeme matriciel autoadhesif pour la liberation prolongee du piribedil par voie transcutanee. |
| JP2819236B2 (ja) * | 1994-05-06 | 1998-10-30 | 日東電工株式会社 | 経皮吸収製剤 |
| GR1002079B (en) * | 1994-07-26 | 1995-12-05 | Lavipharm A E | System of a special structure and composition for the rapid transdermal administration of oestrogens. |
| JP3576608B2 (ja) * | 1994-11-15 | 2004-10-13 | 日東電工株式会社 | 貼付剤および貼付製剤 |
| CN1067875C (zh) * | 1995-04-10 | 2001-07-04 | 浙江省医学科学院 | 雌二醇周效透皮吸收贴片 |
| US5785991A (en) * | 1995-06-07 | 1998-07-28 | Alza Corporation | Skin permeation enhancer compositions comprising glycerol monolaurate and lauryl acetate |
| DE19546024C2 (de) | 1995-12-09 | 1998-09-10 | Lohmann Therapie Syst Lts | Transdermale pharmazeutische Zubereitung und deren Herstellung |
| US5846558A (en) * | 1996-03-19 | 1998-12-08 | Minnesota Mining And Manufacturing Company | Ionically conductive adhesives prepared from zwitterionic materials and medical devices using such adhesives |
| GB9720470D0 (en) | 1997-09-25 | 1997-11-26 | Ethical Pharmaceuticals South | Inhibition of crystallization in transdermal devices |
| US6232366B1 (en) | 1999-06-09 | 2001-05-15 | 3M Innovative Properties Company | Pressure sensitive conductive adhesive having hot-melt properties and biomedical electrodes using same |
| US6709716B2 (en) | 2001-04-27 | 2004-03-23 | 3M Innovative Properties Company | Microemulsion compositions and methods of making and using same |
| US9278155B2 (en) | 2003-06-05 | 2016-03-08 | 3M Innovative Properties Company | Adhesive compositions, articles incorporating same and methods of manufacture |
| US7999023B2 (en) | 2004-12-03 | 2011-08-16 | 3M Innovative Properties Company | Process for making pressure sensitive adhesive hydrogels |
| WO2020201878A1 (en) | 2019-04-01 | 2020-10-08 | 3M Innovative Properties Company | Process for making pressure sensitive adhesive hydrogels |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5777617A (en) * | 1980-10-20 | 1982-05-15 | Nichiban Co Ltd | Plaster for cardiac disease |
| JPS5843368B2 (ja) * | 1980-10-30 | 1983-09-27 | 日東電工株式会社 | 消炎鎮痛貼付剤 |
| US4573996A (en) * | 1984-01-03 | 1986-03-04 | Jonergin, Inc. | Device for the administration of an active agent to the skin or mucosa |
| ATE42901T1 (de) * | 1984-03-05 | 1989-05-15 | Nitto Denko Corp | Haftendes arzneimittelpraeparat fuer perkutane absorption. |
| US4751087A (en) * | 1985-04-19 | 1988-06-14 | Riker Laboratories, Inc. | Transdermal nitroglycerin delivery system |
| AU601528B2 (en) * | 1986-12-22 | 1990-09-13 | Ortho-Mcneil Pharmaceutical, Inc. | Resilient transdermal drug-delivery device and compositions and devices employing fatty acid esters/ethers of alkanediols and percutaneous absorption enhancers |
| US4746515A (en) * | 1987-02-26 | 1988-05-24 | Alza Corporation | Skin permeation enhancer compositions using glycerol monolaurate |
-
1989
- 1989-02-27 JP JP1503327A patent/JP2931002B2/ja not_active Expired - Lifetime
- 1989-02-27 EP EP89903563A patent/EP0402407B1/de not_active Expired - Lifetime
- 1989-02-27 WO PCT/US1989/000786 patent/WO1989007951A1/en not_active Ceased
- 1989-02-27 DE DE68917292T patent/DE68917292T2/de not_active Expired - Lifetime
- 1989-02-27 AT AT89903563T patent/ATE109357T1/de not_active IP Right Cessation
- 1989-02-27 AU AU32809/89A patent/AU630347B2/en not_active Expired
- 1989-03-29 CA CA000594966A patent/CA1338819C/en not_active Expired - Lifetime
-
1992
- 1992-08-13 AU AU20978/92A patent/AU651234B2/en not_active Expired
-
1996
- 1996-12-05 LU LU88849C patent/LU88849I2/fr unknown
-
1997
- 1997-02-14 NL NL970007C patent/NL970007I1/nl unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JPH03502925A (ja) | 1991-07-04 |
| CA1338819C (en) | 1996-12-31 |
| AU2097892A (en) | 1992-10-22 |
| LU88849I2 (fr) | 2003-06-27 |
| NL970007I1 (nl) | 1997-04-01 |
| AU630347B2 (en) | 1992-10-29 |
| EP0402407B1 (de) | 1994-08-03 |
| WO1989007951A1 (en) | 1989-09-08 |
| AU651234B2 (en) | 1994-07-14 |
| DE68917292T2 (de) | 1995-02-02 |
| JP2931002B2 (ja) | 1999-08-09 |
| DE68917292D1 (en) | 1994-09-08 |
| EP0402407A1 (de) | 1990-12-19 |
| AU3280989A (en) | 1989-09-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| EELA | Cancelled due to lapse of time |