ATE109791T1 - Antitumor 6-sulfenamid, 6-sulfinamid und 6- sulfonamid-purine, purin-nukleoside, purin- nukleotide und verwandte verbindungen. - Google Patents

Antitumor 6-sulfenamid, 6-sulfinamid und 6- sulfonamid-purine, purin-nukleoside, purin- nukleotide und verwandte verbindungen.

Info

Publication number
ATE109791T1
ATE109791T1 AT89900773T AT89900773T ATE109791T1 AT E109791 T1 ATE109791 T1 AT E109791T1 AT 89900773 T AT89900773 T AT 89900773T AT 89900773 T AT89900773 T AT 89900773T AT E109791 T1 ATE109791 T1 AT E109791T1
Authority
AT
Austria
Prior art keywords
purine
antitumoric
sulfinamide
sulfenamide
purines
Prior art date
Application number
AT89900773T
Other languages
English (en)
Inventor
Roland Kenith Robins
Ganapathi Ramakrishma Revankar
Naeem Botros Hanna
Original Assignee
Nucleic Acid Research Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nucleic Acid Research Inst filed Critical Nucleic Acid Research Inst
Application granted granted Critical
Publication of ATE109791T1 publication Critical patent/ATE109791T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06Pyrimidine radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/14Pyrrolo-pyrimidine radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16Purine radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16Purine radicals
    • C07H19/20Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT89900773T 1987-12-14 1988-12-13 Antitumor 6-sulfenamid, 6-sulfinamid und 6- sulfonamid-purine, purin-nukleoside, purin- nukleotide und verwandte verbindungen. ATE109791T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13314387A 1987-12-14 1987-12-14
US07/275,113 US5026836A (en) 1987-12-14 1988-11-22 6-sulfenamide, 6-sulfinamide and 6-sulfonamide purines, purine nucleosides, purine nucleotides, pharmaceutical compositions, and processes of making

Publications (1)

Publication Number Publication Date
ATE109791T1 true ATE109791T1 (de) 1994-08-15

Family

ID=26831092

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89900773T ATE109791T1 (de) 1987-12-14 1988-12-13 Antitumor 6-sulfenamid, 6-sulfinamid und 6- sulfonamid-purine, purin-nukleoside, purin- nukleotide und verwandte verbindungen.

Country Status (9)

Country Link
US (1) US5026836A (de)
EP (1) EP0353268B1 (de)
JP (1) JP2698460B2 (de)
KR (1) KR0137763B1 (de)
AR (1) AR247218A1 (de)
AT (1) ATE109791T1 (de)
AU (1) AU2816789A (de)
DE (1) DE3851054T2 (de)
GR (1) GR1000386B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1989011487A1 (en) * 1988-05-23 1989-11-30 United States Of America, Represented By The Secre Derivatives of cyclic amp as treatment for cancer
US6069132A (en) * 1996-08-14 2000-05-30 Revanker; Ganapathi R. Phosphazole compounds
US6531477B1 (en) * 1998-10-13 2003-03-11 Dupont Pharmaceuticals Company 6-substituted pyrazolo [3,4-d] pyrimidin-4-ones useful as cyclin dependent kinase inhibitors

Also Published As

Publication number Publication date
AU2816789A (en) 1989-07-19
EP0353268B1 (de) 1994-08-10
KR900700498A (ko) 1990-08-13
EP0353268A1 (de) 1990-02-07
AR247218A1 (es) 1994-11-30
JP2698460B2 (ja) 1998-01-19
GR1000386B (el) 1992-06-30
DE3851054T2 (de) 1995-03-09
KR0137763B1 (ko) 1998-04-30
EP0353268A4 (de) 1990-05-14
DE3851054D1 (de) 1994-09-15
JPH02502912A (ja) 1990-09-13
US5026836A (en) 1991-06-25

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