ATE109793T1 - Lineare und zyklische analoge von alpha-msh- fragmenten mit ausserordentlicher wirkung. - Google Patents

Lineare und zyklische analoge von alpha-msh- fragmenten mit ausserordentlicher wirkung.

Info

Publication number: ATE109793T1
Authority: AT; Austria
Prior art keywords: linear; alpha; analogues; cyclic analogues; extraordinary effects
Prior art date: 1987-05-22

Application number

AT88304551T

Other languages

English (en)

Inventor

Victor J Hruby

Fahad A Al-Obeidi

Mac E Hadley

Original Assignee

University Patents Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-05-22

Filing date

1988-05-19

Publication date

1994-08-15

1988-05-19 Application filed by University Patents Inc filed Critical University Patents Inc

1994-08-15 Application granted granted Critical

1994-08-15 Publication of ATE109793T1 publication Critical patent/ATE109793T1/de

Links

WHNFPRLDDSXQCL-UAZQEYIDSA-N α-msh Chemical group C([C@@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC=1NC=NC=1)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](C(C)C)C(N)=O)NC(=O)[C@H](CO)NC(C)=O)C1=CC=C(O)C=C1 WHNFPRLDDSXQCL-UAZQEYIDSA-N 0.000 title 1
210000002752 melanocyte Anatomy 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
230000004936 stimulating effect Effects 0.000 abstract 1
230000000699 topical effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
- C07K14/68—Melanocyte-stimulating hormone [MSH]
- C07K14/685—Alpha-melanotropin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Gastroenterology & Hepatology (AREA)
Dermatology (AREA)
Zoology (AREA)
Endocrinology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Toxicology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Peptides Or Proteins (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Saccharide Compounds (AREA)
Diaphragms For Electromechanical Transducers (AREA)
Cosmetics (AREA)
Steroid Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

AT88304551T 1987-05-22 1988-05-19 Lineare und zyklische analoge von alpha-msh- fragmenten mit ausserordentlicher wirkung. ATE109793T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US5322987A	1987-05-22	1987-05-22
CA000578920A CA1340107C (en)	1987-05-22	1988-09-30	Linear and cyclic analoques of alpha-msh fragments with extraordinary potency

Publications (1)

Publication Number	Publication Date
ATE109793T1 true ATE109793T1 (de)	1994-08-15

Family

ID=25672150

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT88304551T ATE109793T1 (de)	1987-05-22	1988-05-19	Lineare und zyklische analoge von alpha-msh- fragmenten mit ausserordentlicher wirkung.

Country Status (11)

Country	Link
EP (1)	EP0292291B1 (de)
JP (1)	JPH0826077B2 (de)
CN (1)	CN1031242C (de)
AT (1)	ATE109793T1 (de)
CA (1)	CA1340107C (de)
DE (1)	DE3851002T2 (de)
DK (1)	DK172760B1 (de)
FI (1)	FI882380A7 (de)
IE (1)	IE64903B1 (de)
PH (1)	PH25819A (de)
PT (1)	PT87560B (de)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5683981A (en) *	1987-05-22	1997-11-04	Competitive Technologies, Inc.	Cyclic bridged analogs of α-MSH and methods thereof
US5674839A (en) *	1987-05-22	1997-10-07	Competitive Technologies, Inc.	Cyclic analogs of alpha-MSH fragments
EP0389950A1 (de) *	1989-03-23	1990-10-03	Lion Corporation	Inhibitor des melanocytenstimulierenden Hormons und dieses enthaltendes, äusserlich anwendbares Präparat
US5071583A (en) *	1990-08-14	1991-12-10	Steve Martell	Soap bar having a fifth finger gripping member
GB9102450D0 (en) *	1991-02-05	1991-03-20	Sandoz Ltd	Improvements in or relating to organic compounds
US5364851A (en) *	1991-06-14	1994-11-15	International Synthecon, Llc	Conformationally restricted biologically active peptides, methods for their production and uses thereof
US6100048A (en) *	1992-04-10	2000-08-08	Oregon Health Sciences University	Methods and reagents for discovering and using mammalian melanocortin receptor agonists and antagonists to modulate feeding behavior in animals
FR2691465B1 (fr) *	1992-05-25	1995-08-11	Pf Medicament	Complexes comprenant au moins un peptide derive de l'alpha msh, peptide, microsphere, medicament et composition galenique les comprenant.
DE69429768T2 (de) *	1993-04-05	2002-09-19	Competitive Technologies, Inc.	Diagnose und behandlung von erektilen funktionsstörungen
FR2710340B1 (fr) *	1993-09-22	1995-12-15	D Hinterland Lucien Dussourd	Dérivés peptidiques de l'alpha-MSH et leur application .
US5420109A (en)	1993-11-12	1995-05-30	Houghten Pharmaceuticals, Inc.	Cytokine restraining agents
US5726156A (en) *	1995-03-06	1998-03-10	Trega Biosciences, Inc.	Cytokine regulatory agents and methods of use in pathologies and conditions associated with altered cytokine levels
US5786332A (en) *	1995-03-06	1998-07-28	Trega Biosciences, Inc.	Cytokine restraining agents and methods of use in pathologies and conditions associated with altered cytokine levels
US6716810B1 (en) *	1998-12-09	2004-04-06	Eleanor Roosevelt Institute	Composition and method for regulation of body weight and associated conditions
ATE393783T1 (de)	1999-03-29	2008-05-15	Procter & Gamble	Melanocortinrezeptor-liganden
TW200716979A (en) *	1999-06-29	2007-05-01	Univ New York	Screening methods for compounds that affect melanogenesis
DE10228837B4 (de) *	2002-06-27	2016-01-07	Elfriede Rauch	Hautkosmetische Zusammensetzung und Verwendung der Zusammensetzung als Hautbräunungsmittel
CN101497654A (zh)	2003-09-30	2009-08-05	诺沃挪第克公司	黑皮素受体激动剂
JP5449673B2 (ja) *	2004-10-08	2014-03-19	クリヌベール、ファーマスーティカルズ、リミテッド	対象者におけるメラニン形成を誘導するための組成物および方法
CN100355776C (zh) *	2005-06-20	2007-12-19	中国人民解放军第二军医大学	一种新型α－黑素细胞刺激素类似物及其用途
AU2006269321A1 (en)	2005-07-08	2007-01-18	Ipsen Pharma S.A.S.	Ligands of melanocortin receptors
US20110130705A1 (en)	2008-03-27	2011-06-02	Clinuvel Pharmaceuticals Limited	Therapy for vitiligo
JP5628796B2 (ja)	2008-06-09	2014-11-19	パラティンテクノロジーズ, インコーポレイテッドPalatin Technologies, Inc.	性的不能の治療用のメラノコルチンレセプタ特異的ペプチド
EP2350031A2 (de)	2008-08-20	2011-08-03	Ensemble Therapeutics Corporation	Makrocyclische verbindungen zur inhibierung des tumornekrosefaktors alpha
UY32690A (es)	2009-06-08	2011-01-31	Astrazeneca Ab	Péptidos específicos para receptores de melanocortina
AU2010321738B2 (en)	2009-11-23	2016-07-14	Palatin Technologies, Inc.	Melanocortin-1 receptor-specific cyclic peptides
EA201290295A1 (ru)	2009-11-23	2013-01-30	Палатин Текнолоджиз, Инк.	Специфичные к рецептору меланокортина-1 линейные пептиды
CN102816211B (zh) *	2012-09-10	2014-07-23	南京工业大学	一种制备美那诺坦的方法
EP2970388B1 (de) *	2013-03-15	2018-07-25	Rhythm Pharmaceuticals, Inc.	Peptidzusammensetzungen

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US448539A (en)		1891-03-17		Cornelius s morris
US4457864A (en) *	1981-10-23	1984-07-03	University Patents, Inc.	Synthetic analogues of α-melanotropin
US4485039A (en) *	1982-06-11	1984-11-27	University Patents, Inc.	Synthetic analogues of α-melanotropin

1988
- 1988-05-19 AT AT88304551T patent/ATE109793T1/de active
- 1988-05-19 EP EP88304551A patent/EP0292291B1/de not_active Expired - Lifetime
- 1988-05-19 DE DE3851002T patent/DE3851002T2/de not_active Expired - Lifetime
- 1988-05-20 IE IE153788A patent/IE64903B1/en not_active IP Right Cessation
- 1988-05-20 DK DK198802777A patent/DK172760B1/da not_active IP Right Cessation
- 1988-05-20 FI FI882380A patent/FI882380A7/fi not_active Application Discontinuation
- 1988-05-20 JP JP63122161A patent/JPH0826077B2/ja not_active Expired - Lifetime
- 1988-05-21 CN CN88104090A patent/CN1031242C/zh not_active Expired - Lifetime
- 1988-05-23 PT PT87560A patent/PT87560B/pt not_active IP Right Cessation
- 1988-05-23 PH PH36969A patent/PH25819A/en unknown
- 1988-09-30 CA CA000578920A patent/CA1340107C/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
AU1650688A (en)	1988-11-24
PT87560A (pt)	1989-05-31
EP0292291B1 (de)	1994-08-10
JPH0826077B2 (ja)	1996-03-13
CN1031242C (zh)	1996-03-13
DK277788A (da)	1988-11-23
DK277788D0 (da)	1988-05-20
CN1032795A (zh)	1989-05-10
EP0292291A2 (de)	1988-11-23
CA1340107C (en)	1998-10-27
IE881537L (en)	1988-11-22
PT87560B (pt)	1992-09-30
DK172760B1 (da)	1999-06-28
DE3851002D1 (de)	1994-09-15
AU618733B2 (en)	1992-01-09
FI882380A7 (fi)	1988-11-23
PH25819A (en)	1991-11-05
JPS6470499A (en)	1989-03-15
DE3851002T2 (de)	1995-02-02
FI882380A0 (fi)	1988-05-20
EP0292291A3 (en)	1990-05-02
IE64903B1 (en)	1995-09-20

Publication	Publication Date	Title
ATE109793T1 (de)	1994-08-15	Lineare und zyklische analoge von alpha-msh- fragmenten mit ausserordentlicher wirkung.
DE68929551D1 (de)	2007-05-10	Menschliche DNase
DE3752364D1 (de)	2003-04-24	Osteoinduktive Zusammensetzungen
FR2712286B1 (fr)	1995-12-22	Nouveaux N-mercaptoalkyl alcanediamines et leur utilisation.
DE69201564D1 (de)	1995-04-06	Verwendung von metalloxidmanopigmenten zum schutz von haarkeratin vor äusseren einflüssen, insbesondere sonnenlicht, verfahren zum schutz des haares und gelzusammensetzung unter verwendung dieser nanopigmente.
DE3779149D1 (de)	1992-06-25	Galanthamin oder dessen analoge zur behandlung der alzheimerschen krankheit.
NO844579L (no)	1985-05-20	Enzymresistente immunomodulerende peptider.
ATE119915T1 (de)	1995-04-15	Dns-sequenzen, rekombinante dns-moleküle und verfahren zur herstellung von ''mullerian inhibiting substance''-ähnlichen polypeptiden.
DE3767400D1 (de)	1991-02-21	Biozide zusammensetzungen und deren verwendung.
DE69230798D1 (de)	2000-04-20	Rekombinante immuntoxine
ATE86488T1 (de)	1993-03-15	Verwendung von minoxidil zur wundheilung.
EP0656791A4 (de)	1997-08-20	Therapeutische zusammensetzungen und verfahren unter verwendung von pqq.
ES2177625T3 (es)	2002-12-16	Citoquina cc-1 humana circulante.
NO890046L (no)	1989-07-21	Disubstituerte pyridiner.
DE69012870D1 (de)	1994-11-03	Gateelektrodenimpulsgenerator zur statischen Var-Kompensation.
ATE76579T1 (de)	1992-06-15	Interferon-zusammensetzungen.
DK67683A (da)	1983-09-04	Fremgangsmaade til fremstilling af 2,3-diaryl-5-halogen-thio-phener
FR2622103B1 (fr)	1990-02-09	Nouvelles compositions dermatologiques bronzantes insectifuges
IT1208760B (it)	1989-07-10	Trattamento delle malattie infiammatorie articolari
ATE87314T1 (de)	1993-04-15	Platin-arzneimittel.
ES551053A0 (es)	1987-03-01	Perfeccionamientos en el metodo de tratamiento de simil-cuero y cuero
DE3586321D1 (de)	1992-08-13	Verwendung von 1,4-dihydropyridinderivaten.
MY104115A (en)	1993-12-31	Linear and cyclic analogs of alpha-msh fragments with extraordinary potency
DE3884407D1 (de)	1993-10-28	Trifluormethyl-1-tetralinabkömmlinge, deren herstellung und verwendung bei der herstellung von verbindungen mit therapeutischer wirkung.
FI880801A7 (fi)	1988-08-21	Puun käsittelyyn tarkoitetut koostumukset ja menetelmät puun käsittelemiseksi.