ATE109793T1 - Lineare und zyklische analoge von alpha-msh- fragmenten mit ausserordentlicher wirkung. - Google Patents

Lineare und zyklische analoge von alpha-msh- fragmenten mit ausserordentlicher wirkung.

Info

Publication number: ATE109793T1
Authority: AT; Austria
Prior art keywords: linear; alpha; analogues; cyclic analogues; extraordinary effects
Prior art date: 1987-05-22

Application number

AT88304551T

Other languages

English (en)

Inventor

Victor J Hruby

Fahad A Al-Obeidi

Mac E Hadley

Original Assignee

University Patents Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-05-22

Filing date

1988-05-19

Publication date

1994-08-15

1988-05-19 Application filed by University Patents Inc filed Critical University Patents Inc

1994-08-15 Application granted granted Critical

1994-08-15 Publication of ATE109793T1 publication Critical patent/ATE109793T1/de

Links

WHNFPRLDDSXQCL-UAZQEYIDSA-N α-msh Chemical group C([C@@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC=1NC=NC=1)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](C(C)C)C(N)=O)NC(=O)[C@H](CO)NC(C)=O)C1=CC=C(O)C=C1 WHNFPRLDDSXQCL-UAZQEYIDSA-N 0.000 title 1
210000002752 melanocyte Anatomy 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
230000004936 stimulating effect Effects 0.000 abstract 1
230000000699 topical effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
- C07K14/68—Melanocyte-stimulating hormone [MSH]
- C07K14/685—Alpha-melanotropin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Gastroenterology & Hepatology (AREA)
Dermatology (AREA)
Zoology (AREA)
Endocrinology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Toxicology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Peptides Or Proteins (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Cosmetics (AREA)
Saccharide Compounds (AREA)
Diaphragms For Electromechanical Transducers (AREA)
Steroid Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

AT88304551T 1987-05-22 1988-05-19 Lineare und zyklische analoge von alpha-msh- fragmenten mit ausserordentlicher wirkung. ATE109793T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US5322987A	1987-05-22	1987-05-22
CA000578920A CA1340107C (en)	1987-05-22	1988-09-30	Linear and cyclic analoques of alpha-msh fragments with extraordinary potency

Publications (1)

Publication Number	Publication Date
ATE109793T1 true ATE109793T1 (de)	1994-08-15

Family

ID=25672150

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT88304551T ATE109793T1 (de)	1987-05-22	1988-05-19	Lineare und zyklische analoge von alpha-msh- fragmenten mit ausserordentlicher wirkung.

Country Status (11)

Country	Link
EP (1)	EP0292291B1 (de)
JP (1)	JPH0826077B2 (de)
CN (1)	CN1031242C (de)
AT (1)	ATE109793T1 (de)
CA (1)	CA1340107C (de)
DE (1)	DE3851002T2 (de)
DK (1)	DK172760B1 (de)
FI (1)	FI882380A7 (de)
IE (1)	IE64903B1 (de)
PH (1)	PH25819A (de)
PT (1)	PT87560B (de)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5683981A (en) *	1987-05-22	1997-11-04	Competitive Technologies, Inc.	Cyclic bridged analogs of α-MSH and methods thereof
US5674839A (en) *	1987-05-22	1997-10-07	Competitive Technologies, Inc.	Cyclic analogs of alpha-MSH fragments
EP0389950A1 (de) *	1989-03-23	1990-10-03	Lion Corporation	Inhibitor des melanocytenstimulierenden Hormons und dieses enthaltendes, äusserlich anwendbares Präparat
US5071583A (en) *	1990-08-14	1991-12-10	Steve Martell	Soap bar having a fifth finger gripping member
GB9102450D0 (en) *	1991-02-05	1991-03-20	Sandoz Ltd	Improvements in or relating to organic compounds
US5364851A (en) *	1991-06-14	1994-11-15	International Synthecon, Llc	Conformationally restricted biologically active peptides, methods for their production and uses thereof
US6100048A (en) *	1992-04-10	2000-08-08	Oregon Health Sciences University	Methods and reagents for discovering and using mammalian melanocortin receptor agonists and antagonists to modulate feeding behavior in animals
FR2691465B1 (fr) *	1992-05-25	1995-08-11	Pf Medicament	Complexes comprenant au moins un peptide derive de l'alpha msh, peptide, microsphere, medicament et composition galenique les comprenant.
WO1994022460A1 (en) *	1993-04-05	1994-10-13	University Patents, Inc.	Diagnosis and treatment of erectile dysfunction
FR2710340B1 (fr) *	1993-09-22	1995-12-15	D Hinterland Lucien Dussourd	Dérivés peptidiques de l'alpha-MSH et leur application .
US5420109A (en)	1993-11-12	1995-05-30	Houghten Pharmaceuticals, Inc.	Cytokine restraining agents
US5726156A (en) *	1995-03-06	1998-03-10	Trega Biosciences, Inc.	Cytokine regulatory agents and methods of use in pathologies and conditions associated with altered cytokine levels
US5786332A (en) *	1995-03-06	1998-07-28	Trega Biosciences, Inc.	Cytokine restraining agents and methods of use in pathologies and conditions associated with altered cytokine levels
US6716810B1 (en) *	1998-12-09	2004-04-06	Eleanor Roosevelt Institute	Composition and method for regulation of body weight and associated conditions
CA2368431C (en)	1999-03-29	2006-01-24	The Procter & Gamble Company	Melanocortin receptor ligands
TW200718944A (en) *	1999-06-29	2007-05-16	Univ New York	Screening methods for compounds that affect melanogenesis
DE10228837B4 (de) *	2002-06-27	2016-01-07	Elfriede Rauch	Hautkosmetische Zusammensetzung und Verwendung der Zusammensetzung als Hautbräunungsmittel
EP1670815A2 (de)	2003-09-30	2006-06-21	Novo Nordisk A/S	Melanocortinrezeptoragonisten
CA2582607C (en) *	2004-10-08	2016-07-12	Clinuvel Pharmaceuticals Limited	Compositions and methods for inducing melanogenesis in a subject
CN100355776C (zh) *	2005-06-20	2007-12-19	中国人民解放军第二军医大学	一种新型α－黑素细胞刺激素类似物及其用途
JP2009500426A (ja)	2005-07-08	2009-01-08	ソシエテ・ドゥ・コンセイユ・ドゥ・ルシェルシュ・エ・ダプリカーション・シャンティフィック・エス・ア・エス	メラノコルチン受容体のリガンド
DK2957292T3 (en)	2008-03-27	2018-01-22	Clinuvel Pharmaceuticals Ltd	VITILIGOTERAPHY
KR101687037B1 (ko)	2008-06-09	2016-12-15	팔라틴 테크놀로지스 인코포레이티드	성기능 장애 치료용 멜라노코르틴 수용체-특이적 펩티드
US8338565B2 (en)	2008-08-20	2012-12-25	Ensemble Therapeutics Corporation	Macrocyclic compounds for inhibition of tumor necrosis factor alpha
UY32690A (es)	2009-06-08	2011-01-31	Astrazeneca Ab	Péptidos específicos para receptores de melanocortina
JP5999702B2 (ja)	2009-11-23	2016-09-28	パラティンテクノロジーズ, インコーポレイテッドPalatin Technologies, Inc.	メラノコルチン−１受容体特異的環状ペプチド
BR112012011780A2 (pt)	2009-11-23	2019-09-24	Palatin Technologies, Inc	peptídeo linear,composição farmacêutica,métodopara tratamento de umadoença,indicação,condição ou sídrome mediadsa por receptor de melanocortina emum mamífero humano ou não humano e método para tratamento de uma condição responsiva ás alterações em função de receptor de melanocortina em um mamifero humano ou não humano
CN102816211B (zh) *	2012-09-10	2014-07-23	南京工业大学	一种制备美那诺坦的方法
EP2970388B1 (de)	2013-03-15	2018-07-25	Rhythm Pharmaceuticals, Inc.	Peptidzusammensetzungen

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US448539A (en)		1891-03-17		Cornelius s morris
US4457864A (en) *	1981-10-23	1984-07-03	University Patents, Inc.	Synthetic analogues of α-melanotropin
US4485039A (en) *	1982-06-11	1984-11-27	University Patents, Inc.	Synthetic analogues of α-melanotropin

1988
- 1988-05-19 EP EP88304551A patent/EP0292291B1/de not_active Expired - Lifetime
- 1988-05-19 DE DE3851002T patent/DE3851002T2/de not_active Expired - Lifetime
- 1988-05-19 AT AT88304551T patent/ATE109793T1/de active
- 1988-05-20 IE IE153788A patent/IE64903B1/en not_active IP Right Cessation
- 1988-05-20 JP JP63122161A patent/JPH0826077B2/ja not_active Expired - Lifetime
- 1988-05-20 FI FI882380A patent/FI882380A7/fi not_active Application Discontinuation
- 1988-05-20 DK DK198802777A patent/DK172760B1/da not_active IP Right Cessation
- 1988-05-21 CN CN88104090A patent/CN1031242C/zh not_active Expired - Lifetime
- 1988-05-23 PH PH36969A patent/PH25819A/en unknown
- 1988-05-23 PT PT87560A patent/PT87560B/pt not_active IP Right Cessation
- 1988-09-30 CA CA000578920A patent/CA1340107C/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
EP0292291A2 (de)	1988-11-23
CA1340107C (en)	1998-10-27
DK172760B1 (da)	1999-06-28
DK277788D0 (da)	1988-05-20
FI882380A0 (fi)	1988-05-20
IE64903B1 (en)	1995-09-20
IE881537L (en)	1988-11-22
EP0292291A3 (en)	1990-05-02
JPS6470499A (en)	1989-03-15
JPH0826077B2 (ja)	1996-03-13
PT87560B (pt)	1992-09-30
FI882380A7 (fi)	1988-11-23
CN1031242C (zh)	1996-03-13
DK277788A (da)	1988-11-23
PH25819A (en)	1991-11-05
PT87560A (pt)	1989-05-31
EP0292291B1 (de)	1994-08-10
AU1650688A (en)	1988-11-24
AU618733B2 (en)	1992-01-09
DE3851002T2 (de)	1995-02-02
DE3851002D1 (de)	1994-09-15
CN1032795A (zh)	1989-05-10

Publication	Publication Date	Title
ATE109793T1 (de)	1994-08-15	Lineare und zyklische analoge von alpha-msh- fragmenten mit ausserordentlicher wirkung.
ATE358176T1 (de)	2007-04-15	Menschliche dnase
ATE419349T1 (de)	2009-01-15	Osteoinduktive zusammensetzungen
FR2712286B1 (fr)	1995-12-22	Nouveaux N-mercaptoalkyl alcanediamines et leur utilisation.
DE69201564D1 (de)	1995-04-06	Verwendung von metalloxidmanopigmenten zum schutz von haarkeratin vor äusseren einflüssen, insbesondere sonnenlicht, verfahren zum schutz des haares und gelzusammensetzung unter verwendung dieser nanopigmente.
KR860004920A (ko)	1986-07-16	뉴클레오시드 및 이의 제조방법
DE3779149D1 (de)	1992-06-25	Galanthamin oder dessen analoge zur behandlung der alzheimerschen krankheit.
FI844510L (fi)	1985-05-19	Ensym-resistenta immunsystemet modulerande peptider.
ATE119915T1 (de)	1995-04-15	Dns-sequenzen, rekombinante dns-moleküle und verfahren zur herstellung von ''mullerian inhibiting substance''-ähnlichen polypeptiden.
FI870484A7 (fi)	1987-08-07	Tekstiilinkäsittelykoostumus ja -menetelmä.
DE69230798D1 (de)	2000-04-20	Rekombinante immuntoxine
ATE86488T1 (de)	1993-03-15	Verwendung von minoxidil zur wundheilung.
ATE73462T1 (de)	1992-03-15	Hirudin-variante, deren verwendung und herstellung.
NO890046D0 (no)	1989-01-05	Disubstituerte pyridiner.
DK67683A (da)	1983-09-04	Fremgangsmaade til fremstilling af 2,3-diaryl-5-halogen-thio-phener
DE3685484D1 (de)	1992-07-02
IT8723062A0 (it)	1987-12-17	Procedimento e dispositivo per registrare punti morti di filatura o torcitura.
FI871607L (fi)	1987-10-15	Menetelmä peptidien valmistamiseksi, menetelmässä käyttökelpoinen yhdistelmäplasmidi ja plasmidilla transformoituja myeloomasoluja
FR2622103B1 (fr)	1990-02-09	Nouvelles compositions dermatologiques bronzantes insectifuges
IT1208760B (it)	1989-07-10	Trattamento delle malattie infiammatorie articolari
ATE87314T1 (de)	1993-04-15	Platin-arzneimittel.
DE3586321D1 (de)	1992-08-13	Verwendung von 1,4-dihydropyridinderivaten.
MY104115A (en)	1993-12-31	Linear and cyclic analogs of alpha-msh fragments with extraordinary potency
DE3884407D1 (de)	1993-10-28	Trifluormethyl-1-tetralinabkömmlinge, deren herstellung und verwendung bei der herstellung von verbindungen mit therapeutischer wirkung.
FI880801A7 (fi)	1988-08-21	Puun käsittelyyn tarkoitetut koostumukset ja menetelmät puun käsittelemiseksi.