PH25819A - Linear, cyclic analog of alpha-msh fragments with extraordinary potency - Google Patents
Linear, cyclic analog of alpha-msh fragments with extraordinary potencyInfo
- Publication number
- PH25819A PH25819A PH36969A PH36969A PH25819A PH 25819 A PH25819 A PH 25819A PH 36969 A PH36969 A PH 36969A PH 36969 A PH36969 A PH 36969A PH 25819 A PH25819 A PH 25819A
- Authority
- PH
- Philippines
- Prior art keywords
- linear
- alpha
- cyclic analog
- extraordinary potency
- msh fragments
- Prior art date
Links
- 125000004122 cyclic group Chemical group 0.000 title 1
- WHNFPRLDDSXQCL-UAZQEYIDSA-N α-msh Chemical group C([C@@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC=1NC=NC=1)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](C(C)C)C(N)=O)NC(=O)[C@H](CO)NC(C)=O)C1=CC=C(O)C=C1 WHNFPRLDDSXQCL-UAZQEYIDSA-N 0.000 title 1
- 210000002752 melanocyte Anatomy 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000004936 stimulating effect Effects 0.000 abstract 1
- 230000000699 topical effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
- C07K14/68—Melanocyte-stimulating hormone [MSH]
- C07K14/685—Alpha-melanotropin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Dermatology (AREA)
- Zoology (AREA)
- Endocrinology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Toxicology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Cosmetics (AREA)
- Saccharide Compounds (AREA)
- Diaphragms For Electromechanical Transducers (AREA)
- Steroid Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US5322987A | 1987-05-22 | 1987-05-22 | |
| CA000578920A CA1340107C (en) | 1987-05-22 | 1988-09-30 | Linear and cyclic analoques of alpha-msh fragments with extraordinary potency |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PH25819A true PH25819A (en) | 1991-11-05 |
Family
ID=25672150
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PH36969A PH25819A (en) | 1987-05-22 | 1988-05-23 | Linear, cyclic analog of alpha-msh fragments with extraordinary potency |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP0292291B1 (de) |
| JP (1) | JPH0826077B2 (de) |
| CN (1) | CN1031242C (de) |
| AT (1) | ATE109793T1 (de) |
| CA (1) | CA1340107C (de) |
| DE (1) | DE3851002T2 (de) |
| DK (1) | DK172760B1 (de) |
| FI (1) | FI882380A7 (de) |
| IE (1) | IE64903B1 (de) |
| PH (1) | PH25819A (de) |
| PT (1) | PT87560B (de) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5683981A (en) * | 1987-05-22 | 1997-11-04 | Competitive Technologies, Inc. | Cyclic bridged analogs of α-MSH and methods thereof |
| US5674839A (en) * | 1987-05-22 | 1997-10-07 | Competitive Technologies, Inc. | Cyclic analogs of alpha-MSH fragments |
| EP0389950A1 (de) * | 1989-03-23 | 1990-10-03 | Lion Corporation | Inhibitor des melanocytenstimulierenden Hormons und dieses enthaltendes, äusserlich anwendbares Präparat |
| US5071583A (en) * | 1990-08-14 | 1991-12-10 | Steve Martell | Soap bar having a fifth finger gripping member |
| GB9102450D0 (en) * | 1991-02-05 | 1991-03-20 | Sandoz Ltd | Improvements in or relating to organic compounds |
| US5364851A (en) * | 1991-06-14 | 1994-11-15 | International Synthecon, Llc | Conformationally restricted biologically active peptides, methods for their production and uses thereof |
| US6100048A (en) * | 1992-04-10 | 2000-08-08 | Oregon Health Sciences University | Methods and reagents for discovering and using mammalian melanocortin receptor agonists and antagonists to modulate feeding behavior in animals |
| FR2691465B1 (fr) * | 1992-05-25 | 1995-08-11 | Pf Medicament | Complexes comprenant au moins un peptide derive de l'alpha msh, peptide, microsphere, medicament et composition galenique les comprenant. |
| WO1994022460A1 (en) * | 1993-04-05 | 1994-10-13 | University Patents, Inc. | Diagnosis and treatment of erectile dysfunction |
| FR2710340B1 (fr) * | 1993-09-22 | 1995-12-15 | D Hinterland Lucien Dussourd | Dérivés peptidiques de l'alpha-MSH et leur application . |
| US5420109A (en) | 1993-11-12 | 1995-05-30 | Houghten Pharmaceuticals, Inc. | Cytokine restraining agents |
| US5726156A (en) * | 1995-03-06 | 1998-03-10 | Trega Biosciences, Inc. | Cytokine regulatory agents and methods of use in pathologies and conditions associated with altered cytokine levels |
| US5786332A (en) * | 1995-03-06 | 1998-07-28 | Trega Biosciences, Inc. | Cytokine restraining agents and methods of use in pathologies and conditions associated with altered cytokine levels |
| US6716810B1 (en) * | 1998-12-09 | 2004-04-06 | Eleanor Roosevelt Institute | Composition and method for regulation of body weight and associated conditions |
| CA2368431C (en) | 1999-03-29 | 2006-01-24 | The Procter & Gamble Company | Melanocortin receptor ligands |
| TW200718944A (en) * | 1999-06-29 | 2007-05-16 | Univ New York | Screening methods for compounds that affect melanogenesis |
| DE10228837B4 (de) * | 2002-06-27 | 2016-01-07 | Elfriede Rauch | Hautkosmetische Zusammensetzung und Verwendung der Zusammensetzung als Hautbräunungsmittel |
| EP1670815A2 (de) | 2003-09-30 | 2006-06-21 | Novo Nordisk A/S | Melanocortinrezeptoragonisten |
| CA2582607C (en) * | 2004-10-08 | 2016-07-12 | Clinuvel Pharmaceuticals Limited | Compositions and methods for inducing melanogenesis in a subject |
| CN100355776C (zh) * | 2005-06-20 | 2007-12-19 | 中国人民解放军第二军医大学 | 一种新型α-黑素细胞刺激素类似物及其用途 |
| JP2009500426A (ja) | 2005-07-08 | 2009-01-08 | ソシエテ・ドゥ・コンセイユ・ドゥ・ルシェルシュ・エ・ダプリカーション・シャンティフィック・エス・ア・エス | メラノコルチン受容体のリガンド |
| DK2957292T3 (en) | 2008-03-27 | 2018-01-22 | Clinuvel Pharmaceuticals Ltd | VITILIGOTERAPHY |
| KR101687037B1 (ko) | 2008-06-09 | 2016-12-15 | 팔라틴 테크놀로지스 인코포레이티드 | 성기능 장애 치료용 멜라노코르틴 수용체-특이적 펩티드 |
| US8338565B2 (en) | 2008-08-20 | 2012-12-25 | Ensemble Therapeutics Corporation | Macrocyclic compounds for inhibition of tumor necrosis factor alpha |
| UY32690A (es) | 2009-06-08 | 2011-01-31 | Astrazeneca Ab | Péptidos específicos para receptores de melanocortina |
| JP5999702B2 (ja) | 2009-11-23 | 2016-09-28 | パラティン テクノロジーズ, インコーポレイテッドPalatin Technologies, Inc. | メラノコルチン−1受容体特異的環状ペプチド |
| BR112012011780A2 (pt) | 2009-11-23 | 2019-09-24 | Palatin Technologies, Inc | peptídeo linear,composição farmacêutica,métodopara tratamento de umadoença,indicação,condição ou sídrome mediadsa por receptor de melanocortina emum mamífero humano ou não humano e método para tratamento de uma condição responsiva ás alterações em função de receptor de melanocortina em um mamifero humano ou não humano |
| CN102816211B (zh) * | 2012-09-10 | 2014-07-23 | 南京工业大学 | 一种制备美那诺坦的方法 |
| EP2970388B1 (de) | 2013-03-15 | 2018-07-25 | Rhythm Pharmaceuticals, Inc. | Peptidzusammensetzungen |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US448539A (en) | 1891-03-17 | Cornelius s morris | ||
| US4457864A (en) * | 1981-10-23 | 1984-07-03 | University Patents, Inc. | Synthetic analogues of α-melanotropin |
| US4485039A (en) * | 1982-06-11 | 1984-11-27 | University Patents, Inc. | Synthetic analogues of α-melanotropin |
-
1988
- 1988-05-19 EP EP88304551A patent/EP0292291B1/de not_active Expired - Lifetime
- 1988-05-19 DE DE3851002T patent/DE3851002T2/de not_active Expired - Lifetime
- 1988-05-19 AT AT88304551T patent/ATE109793T1/de active
- 1988-05-20 IE IE153788A patent/IE64903B1/en not_active IP Right Cessation
- 1988-05-20 JP JP63122161A patent/JPH0826077B2/ja not_active Expired - Lifetime
- 1988-05-20 FI FI882380A patent/FI882380A7/fi not_active Application Discontinuation
- 1988-05-20 DK DK198802777A patent/DK172760B1/da not_active IP Right Cessation
- 1988-05-21 CN CN88104090A patent/CN1031242C/zh not_active Expired - Lifetime
- 1988-05-23 PH PH36969A patent/PH25819A/en unknown
- 1988-05-23 PT PT87560A patent/PT87560B/pt not_active IP Right Cessation
- 1988-09-30 CA CA000578920A patent/CA1340107C/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP0292291A2 (de) | 1988-11-23 |
| CA1340107C (en) | 1998-10-27 |
| DK172760B1 (da) | 1999-06-28 |
| DK277788D0 (da) | 1988-05-20 |
| FI882380A0 (fi) | 1988-05-20 |
| IE64903B1 (en) | 1995-09-20 |
| IE881537L (en) | 1988-11-22 |
| EP0292291A3 (en) | 1990-05-02 |
| JPS6470499A (en) | 1989-03-15 |
| JPH0826077B2 (ja) | 1996-03-13 |
| PT87560B (pt) | 1992-09-30 |
| ATE109793T1 (de) | 1994-08-15 |
| FI882380A7 (fi) | 1988-11-23 |
| CN1031242C (zh) | 1996-03-13 |
| DK277788A (da) | 1988-11-23 |
| PT87560A (pt) | 1989-05-31 |
| EP0292291B1 (de) | 1994-08-10 |
| AU1650688A (en) | 1988-11-24 |
| AU618733B2 (en) | 1992-01-09 |
| DE3851002T2 (de) | 1995-02-02 |
| DE3851002D1 (de) | 1994-09-15 |
| CN1032795A (zh) | 1989-05-10 |
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