ATE109831T1 - Defektives rekombinantes retrovirus, seine verwendung zur integration von proteine codierenden sequenzen im genom von gewebekulturen, infizierbar mit dem entsprechenden wildretrovirus, und dns zur herstellung dieses rekombinanten retrovirus. - Google Patents

Defektives rekombinantes retrovirus, seine verwendung zur integration von proteine codierenden sequenzen im genom von gewebekulturen, infizierbar mit dem entsprechenden wildretrovirus, und dns zur herstellung dieses rekombinanten retrovirus.

Info

Publication number
ATE109831T1
ATE109831T1 AT89400890T AT89400890T ATE109831T1 AT E109831 T1 ATE109831 T1 AT E109831T1 AT 89400890 T AT89400890 T AT 89400890T AT 89400890 T AT89400890 T AT 89400890T AT E109831 T1 ATE109831 T1 AT E109831T1
Authority
AT
Austria
Prior art keywords
retrovirus
recombinant retrovirus
genome
dna
protein coding
Prior art date
Application number
AT89400890T
Other languages
English (en)
Inventor
Thierry Heidmann
Jean-Francois Nicolas
Original Assignee
Pasteur Institut
Inst Nat Sante Rech Med
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pasteur Institut, Inst Nat Sante Rech Med filed Critical Pasteur Institut
Application granted granted Critical
Publication of ATE109831T1 publication Critical patent/ATE109831T1/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/13011—Gammaretrovirus, e.g. murine leukeamia virus
    • C12N2740/13041—Use of virus, viral particle or viral elements as a vector
    • C12N2740/13043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Manufacture, Treatment Of Glass Fibers (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT89400890T 1988-03-31 1989-03-30 Defektives rekombinantes retrovirus, seine verwendung zur integration von proteine codierenden sequenzen im genom von gewebekulturen, infizierbar mit dem entsprechenden wildretrovirus, und dns zur herstellung dieses rekombinanten retrovirus. ATE109831T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8804332A FR2629469B1 (fr) 1988-03-31 1988-03-31 Retrovirus recombinant defectif, son application a l'integration de sequences codantes pour des proteines determinees dans le genome de cultures cellulaires infectables par le retrovirus sauvage correspondant et adns recombinants pour la production de ce retrovirus recombinant

Publications (1)

Publication Number Publication Date
ATE109831T1 true ATE109831T1 (de) 1994-08-15

Family

ID=9364870

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89400890T ATE109831T1 (de) 1988-03-31 1989-03-30 Defektives rekombinantes retrovirus, seine verwendung zur integration von proteine codierenden sequenzen im genom von gewebekulturen, infizierbar mit dem entsprechenden wildretrovirus, und dns zur herstellung dieses rekombinanten retrovirus.

Country Status (10)

Country Link
US (1) US5583022A (de)
EP (1) EP0336822B1 (de)
JP (1) JPH0213384A (de)
AT (1) ATE109831T1 (de)
CA (1) CA1341258C (de)
DE (1) DE68917349T2 (de)
DK (1) DK158389A (de)
ES (1) ES2058565T3 (de)
FR (1) FR2629469B1 (de)
PT (1) PT90185B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0564645B1 (de) * 1991-10-30 1999-12-29 Universite Pierre Et Marie Curie Paris Vi Transformierte zellen zur verhütung oder zur behandlung von virus-induzierten erkrankungen,besonders pathogenen retroviren
FR2737731B1 (fr) * 1995-08-07 1997-10-10 Pasteur Institut Sequence de retroelements naturels ou synthetiques ayant pour fonction de permettre l'insertion de sequences nucleotidiques dans une cellule eucaryote
AU758262B2 (en) * 1995-08-07 2003-03-20 Institut Pasteur Natural or synthetic retroelements enabling nucleotide sequence insertion into a eukaryotic cell
US5994136A (en) * 1997-12-12 1999-11-30 Cell Genesys, Inc. Method and means for producing high titer, safe, recombinant lentivirus vectors
EP1129178A4 (de) * 1998-11-13 2002-08-21 Cell Genesys Inc Empfindliches 'screening'-system für rekombinante viren mit defekter hülle.
ATE528406T1 (de) 1999-04-29 2011-10-15 Gbp Ip Llc Verfahren und mittel zur herstellung von sicheren,rekombinanten lentivirusvektoren mit hohem titer
AU2002254212A1 (en) * 2001-03-12 2002-09-24 Irm, Llc Identification of cellular targets for biologically active molecules
AU2002252370A1 (en) * 2001-03-12 2002-09-24 Irm, Llc. Genomics-driven high speed cellular assays, development thereof, and collections of cellular reporters
ATE437221T1 (de) * 2001-05-14 2009-08-15 Gbp Ip Llc Lentivirale vektoren kodierend für gerinnungsfaktoren für die gentherapie

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60224492A (ja) * 1984-04-24 1985-11-08 Yuu Honshiyo 異種遺伝子の結合法
EP0192658A4 (de) * 1984-07-30 1987-07-13 Salk Inst For Biological Studi Retrovirale gentransfervektoren.
GB8424757D0 (en) * 1984-10-01 1984-11-07 Pasteur Institut Retroviral vector
AU582288B2 (en) * 1986-03-07 1989-03-16 Damon Biotech Inc. Vector and method for achieving high level expression in eukaryotic cells

Also Published As

Publication number Publication date
CA1341258C (fr) 2001-06-19
DK158389D0 (da) 1989-03-31
FR2629469A1 (fr) 1989-10-06
PT90185A (pt) 1989-11-10
EP0336822A1 (de) 1989-10-11
ES2058565T3 (es) 1994-11-01
US5583022A (en) 1996-12-10
JPH0213384A (ja) 1990-01-17
PT90185B (pt) 1994-10-31
DK158389A (da) 1989-10-01
DE68917349T2 (de) 1995-02-02
FR2629469B1 (fr) 1990-12-21
DE68917349D1 (de) 1994-09-15
EP0336822B1 (de) 1994-08-10

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