ATE110390T1 - Wachstumsfaktor-rezeptor. - Google Patents

Wachstumsfaktor-rezeptor.

Info

Publication number: ATE110390T1
Authority: AT; Austria
Prior art keywords: bombesin; antagonists; growth factor; factor receptor; spantide
Prior art date: 1987-03-31

Application number

AT88902901T

Other languages

English (en)

Inventor

Enrique Rosengurt

Ian Zachary

Penella Woll

Original Assignee

Imp Cancer Res Tech

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-03-31

Filing date

1988-03-31

Publication date

1994-09-15

1987-03-31 Priority claimed from GB878707607A external-priority patent/GB8707607D0/en

1987-11-25 Priority claimed from GB878727638A external-priority patent/GB8727638D0/en

1988-03-31 Application filed by Imp Cancer Res Tech filed Critical Imp Cancer Res Tech

1994-09-15 Application granted granted Critical

1994-09-15 Publication of ATE110390T1 publication Critical patent/ATE110390T1/de

Links

102000009465 Growth Factor Receptors Human genes 0.000 title 1
108010009202 Growth Factor Receptors Proteins 0.000 title 1
239000005557 antagonist Substances 0.000 abstract 3
102000013585 Bombesin Human genes 0.000 abstract 2
108010051479 Bombesin Proteins 0.000 abstract 2
DNDCVAGJPBKION-DOPDSADYSA-N bombesin Chemical compound C([C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(N)=O)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CC=1NC2=CC=CC=C2C=1)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H]1NC(=O)CC1)C(C)C)C1=CN=CN1 DNDCVAGJPBKION-DOPDSADYSA-N 0.000 abstract 2
229920001184 polypeptide Polymers 0.000 abstract 2
102000004196 processed proteins & peptides Human genes 0.000 abstract 2
108090000765 processed proteins & peptides Proteins 0.000 abstract 2
ONIBWKKTOPOVIA-SCSAIBSYSA-N D-Proline Chemical compound OC(=O)[C@H]1CCCN1 ONIBWKKTOPOVIA-SCSAIBSYSA-N 0.000 abstract 1
COLNVLDHVKWLRT-MRVPVSSYSA-N D-phenylalanine Chemical compound OC(=O)[C@H](N)CC1=CC=CC=C1 COLNVLDHVKWLRT-MRVPVSSYSA-N 0.000 abstract 1
-1 [D-Pro<2>]-spantide Chemical compound 0.000 abstract 1
230000004663 cell proliferation Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Genetics & Genomics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Zoology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
General Health & Medical Sciences (AREA)
Toxicology (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Gastroenterology & Hepatology (AREA)
Endocrinology (AREA)
Cell Biology (AREA)
Immunology (AREA)
Peptides Or Proteins (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

AT88902901T 1987-03-31 1988-03-31 Wachstumsfaktor-rezeptor. ATE110390T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB878707607A GB8707607D0 (en)	1987-03-31	1987-03-31	Growth factor receptors
GB878727638A GB8727638D0 (en)	1987-11-25	1987-11-25	Improvements relating to growth factor receptors

Publications (1)

Publication Number	Publication Date
ATE110390T1 true ATE110390T1 (de)	1994-09-15

Family

ID=26292080

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT88902901T ATE110390T1 (de)	1987-03-31	1988-03-31	Wachstumsfaktor-rezeptor.

Country Status (5)

Country	Link
EP (1)	EP0359745B1 (de)
JP (1)	JP2728476B2 (de)
AT (1)	ATE110390T1 (de)
DE (1)	DE3851226T2 (de)
WO (1)	WO1988007551A2 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5434132A (en) *	1988-03-21	1995-07-18	Imperial Cancer Research Technology, Ltd.	Neuropeptide antagonists
GB8806644D0 (en) *	1988-03-21	1988-04-20	Imp Cancer Res Tech	Neuropeptide antagonists
US5215963A (en) *	1989-10-24	1993-06-01	Berlex Laboratories, Inc.	Solubilization and purification of the active gastrin releasing peptide receptor
DE3940209A1 (de) *	1989-12-05	1991-06-06	Boehringer Mannheim Gmbh	Verfahren zum nachweis eines kleinzelligen bronchial-karzinoms
HU209312B (en) *	1992-02-11	1994-04-28	Richter Gedeon Vegyeszet	Process for producing short peptide and pseudopeptide amides inhibiting the proliferation of the cells of small cellular and epithelial lung cancer, as well as pharmaceutical compositions comprising same as active ingredient
US6602856B1 (en) *	1995-01-17	2003-08-05	J. Mark Quillan	Antagonists of alpha-melanocyte stimulating hormone and methods based thereon
GB0011100D0 (en) *	2000-05-08	2000-06-28	Matrix Therapeutics Limited	Small peptide amides inhibiting the proliferation of cancer cells
WO2002102835A2 (en) *	2000-11-21	2002-12-27	New England Medical Center	Novel antimicrobial compounds

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4481139A (en) *	1983-04-13	1984-11-06	Board Of Regents, The University Of Texas System	Peptide antagonists of substance P

1988
- 1988-03-31 DE DE3851226T patent/DE3851226T2/de not_active Expired - Fee Related
- 1988-03-31 EP EP88902901A patent/EP0359745B1/de not_active Expired - Lifetime
- 1988-03-31 JP JP63502924A patent/JP2728476B2/ja not_active Expired - Fee Related
- 1988-03-31 AT AT88902901T patent/ATE110390T1/de active
- 1988-03-31 WO PCT/GB1988/000255 patent/WO1988007551A2/en not_active Ceased

Also Published As

Publication number	Publication date
WO1988007551A2 (en)	1988-10-06
EP0359745B1 (de)	1994-08-24
JPH02503195A (ja)	1990-10-04
WO1988007551A3 (en)	1990-02-22
DE3851226D1 (de)	1994-09-29
JP2728476B2 (ja)	1998-03-18
EP0359745A1 (de)	1990-03-28
DE3851226T2 (de)	1994-12-08

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