ATE111524T1 - Mutanter stamm von einem methylotrophen organismus und verfahren zur herstellung eines proteins in methylotrophen organismus. - Google Patents
Mutanter stamm von einem methylotrophen organismus und verfahren zur herstellung eines proteins in methylotrophen organismus.Info
- Publication number
- ATE111524T1 ATE111524T1 AT88121327T AT88121327T ATE111524T1 AT E111524 T1 ATE111524 T1 AT E111524T1 AT 88121327 T AT88121327 T AT 88121327T AT 88121327 T AT88121327 T AT 88121327T AT E111524 T1 ATE111524 T1 AT E111524T1
- Authority
- AT
- Austria
- Prior art keywords
- methylotrophic
- expression
- protein
- organism
- methanol
- Prior art date
Links
- 108090000623 proteins and genes Proteins 0.000 title abstract 9
- 102000004169 proteins and genes Human genes 0.000 title abstract 6
- 238000000034 method Methods 0.000 title abstract 3
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 6
- 230000014509 gene expression Effects 0.000 abstract 4
- 108010025188 Alcohol oxidase Proteins 0.000 abstract 2
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 2
- 230000002950 deficient Effects 0.000 abstract 2
- 230000001939 inductive effect Effects 0.000 abstract 2
- 238000004519 manufacturing process Methods 0.000 abstract 2
- 102000016938 Catalase Human genes 0.000 abstract 1
- 108010053835 Catalase Proteins 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 210000000349 chromosome Anatomy 0.000 abstract 1
- 230000002018 overexpression Effects 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
- C12N15/815—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP88121327A EP0374282B1 (de) | 1988-12-20 | 1988-12-20 | Mutanter Stamm von einem methylotrophen Organismus und Verfahren zur Herstellung eines Proteins in methylotrophen Organismus |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE111524T1 true ATE111524T1 (de) | 1994-09-15 |
Family
ID=8199690
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT88121327T ATE111524T1 (de) | 1988-12-20 | 1988-12-20 | Mutanter stamm von einem methylotrophen organismus und verfahren zur herstellung eines proteins in methylotrophen organismus. |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP0374282B1 (de) |
| JP (1) | JPH02276568A (de) |
| AT (1) | ATE111524T1 (de) |
| DE (1) | DE3851535T2 (de) |
| ES (1) | ES2065331T3 (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5204261A (en) * | 1991-04-24 | 1993-04-20 | Phillips Petroleum Company | Catalase-negative pichia pastoris |
| CA2101610A1 (en) * | 1992-08-07 | 1994-02-08 | William D. Prevatt | Production of bacillus entomotoxins in methylotrophic yeast |
| JPH06209763A (ja) * | 1993-01-13 | 1994-08-02 | Green Cross Corp:The | 変異株 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1341130C (en) * | 1984-07-27 | 2000-10-31 | Adrianus Marinus Ledeboer | Use of oxidoreductases in bleaching and/or detergent compositions and their preparation by microorganisms engineered by recombinant dna technology |
| US4855231A (en) * | 1984-10-30 | 1989-08-08 | Phillips Petroleum Company | Regulatory region for heterologous gene expression in yeast |
| EP0242007B1 (de) * | 1986-11-24 | 1990-11-07 | Unilever N.V. | Verfahren zur Herstellung einer catalasefreien, Oxidase enthaltenden Hefe und deren Verwendung |
-
1988
- 1988-12-20 AT AT88121327T patent/ATE111524T1/de not_active IP Right Cessation
- 1988-12-20 ES ES88121327T patent/ES2065331T3/es not_active Expired - Lifetime
- 1988-12-20 DE DE3851535T patent/DE3851535T2/de not_active Expired - Fee Related
- 1988-12-20 EP EP88121327A patent/EP0374282B1/de not_active Expired - Lifetime
-
1989
- 1989-12-19 JP JP1329426A patent/JPH02276568A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP0374282B1 (de) | 1994-09-14 |
| DE3851535T2 (de) | 1995-02-02 |
| ES2065331T3 (es) | 1995-02-16 |
| JPH02276568A (ja) | 1990-11-13 |
| DE3851535D1 (de) | 1994-10-20 |
| EP0374282A1 (de) | 1990-06-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |