ATE112277T1 - Neues s-timolol derivat und verfahren zu seiner herstellung. - Google Patents

Neues s-timolol derivat und verfahren zu seiner herstellung.

Info

Publication number
ATE112277T1
ATE112277T1 AT89911378T AT89911378T ATE112277T1 AT E112277 T1 ATE112277 T1 AT E112277T1 AT 89911378 T AT89911378 T AT 89911378T AT 89911378 T AT89911378 T AT 89911378T AT E112277 T1 ATE112277 T1 AT E112277T1
Authority
AT
Austria
Prior art keywords
new
production
timolol
derivative
timolol derivative
Prior art date
Application number
AT89911378T
Other languages
English (en)
Inventor
Markku Peraelampi
Original Assignee
Leiras Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leiras Oy filed Critical Leiras Oy
Application granted granted Critical
Publication of ATE112277T1 publication Critical patent/ATE112277T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01—Five-membered rings
    • C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/10—1,2,5-Thiadiazoles; Hydrogenated 1,2,5-thiadiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Control Of El Displays (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
AT89911378T 1988-10-20 1989-10-13 Neues s-timolol derivat und verfahren zu seiner herstellung. ATE112277T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FI884838A FI82240C (fi) 1988-10-20 1988-10-20 Foerfarande foer framstaellning av farmakologiskt vaerdefullt s-timolol-hemihydrat.

Publications (1)

Publication Number Publication Date
ATE112277T1 true ATE112277T1 (de) 1994-10-15

Family

ID=8527232

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89911378T ATE112277T1 (de) 1988-10-20 1989-10-13 Neues s-timolol derivat und verfahren zu seiner herstellung.

Country Status (12)

Country Link
US (4) US5231095A (de)
EP (1) EP0440684B1 (de)
JP (1) JP2949508B2 (de)
AT (1) ATE112277T1 (de)
AU (1) AU624431B2 (de)
CA (1) CA2001083C (de)
DE (1) DE68918597T2 (de)
DK (1) DK175377B1 (de)
FI (1) FI82240C (de)
NO (1) NO179838C (de)
NZ (1) NZ231057A (de)
WO (1) WO1990004592A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI82240C (fi) * 1988-10-20 1991-02-11 Huhtamaeki Oy Foerfarande foer framstaellning av farmakologiskt vaerdefullt s-timolol-hemihydrat.
US5496820A (en) * 1988-10-20 1996-03-05 Peraelampi; Markku Ophthalmic use of S-timolol hemihydrate
TW208013B (de) * 1990-03-01 1993-06-21 Daiichi Co Ltd
ATE154513T1 (de) * 1992-07-08 1997-07-15 Leiras Oy Augenarzneimittel enthaltend timolol hemihydrat
US20060143783A1 (en) * 2004-12-15 2006-07-06 Berman Paul K Energy diffusing glove insert
US7862552B2 (en) 2005-05-09 2011-01-04 Boston Scientific Scimed, Inc. Medical devices for treating urological and uterine conditions
CN101622243B (zh) 2007-02-28 2013-12-04 旭化成制药株式会社 磺酰胺衍生物

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3657237A (en) * 1968-05-22 1972-04-18 Frosst & Co Charles E Process for making 1 2 5-thiadiazoles in the sinister configuration
US4428883A (en) * 1981-03-06 1984-01-31 The University Of Kentucky Research Foundation Novel method of administering β-blockers and novel dosage forms containing same
FI71933C (fi) * 1984-03-30 1989-04-06 Star Oy Ab Nya l-vinsyra-0-monoestrar av 3-morfolino-4-(3'-tert.-butylamino-2'-hydroxipropoxi)-1,2,5-tiadiazol och deras anvaendning saosom mellanprodukter.
JPS60226855A (ja) * 1984-04-26 1985-11-12 Nippon Kayaku Co Ltd Ｎ−ベンジルオキシカルボニル−ｌ−スレオニンアミド・１／２水和物およびその製造法
US4752478A (en) * 1984-12-17 1988-06-21 Merck & Co., Inc. Transdermal system for timolol
US4756710A (en) * 1985-04-05 1988-07-12 Merck & Co., Inc. pH-Mediated drug delivery system
FI82240C (fi) * 1988-10-20 1991-02-11 Huhtamaeki Oy Foerfarande foer framstaellning av farmakologiskt vaerdefullt s-timolol-hemihydrat.

Also Published As

Publication number Publication date
NZ231057A (en) 1990-11-27
CA2001083A1 (en) 1990-04-20
NO179838B (no) 1996-09-16
JP2949508B2 (ja) 1999-09-13
FI82240C (fi) 1991-02-11
AU624431B2 (en) 1992-06-11
CA2001083C (en) 1999-06-15
WO1990004592A1 (en) 1990-05-03
US5231095A (en) 1993-07-27
NO911508L (no) 1991-04-17
US5354860A (en) 1994-10-11
DK72591A (da) 1991-04-19
NO179838C (no) 1996-12-27
AU4347389A (en) 1990-05-14
EP0440684A1 (de) 1991-08-14
NO911508D0 (no) 1991-04-17
JPH04502612A (ja) 1992-05-14
US5574035A (en) 1996-11-12
DK175377B1 (da) 2004-09-20
FI82240B (fi) 1990-10-31
FI884838L (fi) 1990-04-21
EP0440684B1 (de) 1994-09-28
DK72591D0 (da) 1991-04-19
US5541184A (en) 1996-07-30
FI884838A0 (fi) 1988-10-20
DE68918597T2 (de) 1995-05-11
DE68918597D1 (de) 1994-11-03

Similar Documents

Publication Publication Date Title
ES2059408T3 (es) Un proceso para la preparacion de un compuesto.
DE3483629D1 (de) 2-pyrimidinyl-l-piperazin-derivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel.
MY103850A (en) Phenol substituted gem-diphosphonate derivatives, process for their preparation and pharmaceutical compositions containing them.
ATE36699T1 (de) Chinonderivate, verfahren zu ihrer herstellung, ihre verwendung und pharmazeutische zusammensetzung.
ATE13056T1 (de) Indanderivate, verfahren zu ihrer herstellung und sie enthaltende zusammensetzungen.
ATE186728T1 (de) Imidazochinoxalinone, ihre azaanaloge und verfahren zu ihrer herstellung
DE3481840D1 (de) 3-(4-piperidinyl)-1,2-benzisothiazole und deren derivate, verfahren zu ihrer herstellung und verwendung als arzneimittel.
ES8201549A1 (es) Procedimiento para la obtencion de derivados de 3,4,5-trihi-droxipiperidina
ATE1581T1 (de) 3,4,5-trihydroxypiperidin-derivate, verfahren zu ihrer herstellung sowie diese enthaltende arzneimittel und tierfuttermittel.
UA35607C2 (uk) Похідні оксазолідинонкарбонової кислоти, спосіб їх одержання, фармацевтична композиція і спосіб її одержання
DE69608548D1 (de) 10- deacetylbaccatin iii und 10- deacetyl 14 beta hydroxybaccatin iii derivaten, verfahren zu deren herstellung und diese enthaltende pharmazeutischen zusammenstellungen
ATE112277T1 (de) Neues s-timolol derivat und verfahren zu seiner herstellung.
HUT46664A (en) Process for producing new dihydropyridineamide derivatives and pharmaceutical compositions comprising these compounds
ATE152118T1 (de) Kardioaktive 17b-(3-furyl) und 17b-(4- pyridazinyl)-5beta, 14beta-androstan derivate, verfahren zu ihrer herstellung und pharmazeutische präparate davon
NZ322318A (en) Method for preparing camptothecin derivatives
DE3769563D1 (de) Neue derivate von 4,5-dihydro-oxazolen, verfahren zu ihrer herstellung und ihre verwendung.
DE69710909D1 (de) Substituierte tetrahydropyridinderivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
ATE200492T1 (de) 7-acyl-3-(substituierte carbamoyloxy) cephem verbindungen, verfahren zu ihrer herstellung und anwendung
DE3480839D1 (de) Benzimidazol-derivat, verfahren zu seiner herstellung und pharmazeutische zusammensetzung.
ATE118004T1 (de) 4-amidino-chroman und 4-amidino-pyrano(3,2- c)pyridinderivate, verfahren zur herstellung und diese enthaltende pharmazeutische zusammenstellungen.
DE3461187D1 (en) N-cyclopropylmethyl-2-oxo-3-diparamethoxyphenyl-5,6-triazines, process for its preparation and their use as pharmaceutical preparations
ATE50566T1 (de) 5-cyanopyridine-2-diazohydroxide, basische salze und verfahren zu ihrer herstellung und anwendung.
ES8601200A1 (es) Un procedimiento para preparar compuestos de 3-(2-haloetil)-4-oxopirazolo-(5, 1-d)-1, 2, 3, 5-tetrazin-8-carboxamida
ES8203843A1 (es) Procedimiento para la obtencion de amidas de acido 1,4-dihi-dropiridin-4-carboxilico
PT81427A (de) 3,4-diazolderivate verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Legal Events

Date Code Title Description
EEIH Change in the person of patent owner
EELA Cancelled due to lapse of time