ATE112287T1 - Faktor viii- gelfiltration. - Google Patents

Faktor viii- gelfiltration.

Info

Publication number: ATE112287T1
Authority: AT; Austria
Prior art keywords: gel filtration; factor viii; peg precipitation; filtration step; adsorption
Prior art date: 1987-12-21

Application number

AT88120808T

Other languages

English (en)

Inventor

William J Brockway

Richard L Seng

Original Assignee

Miles Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-12-21

Filing date

1988-12-13

Publication date

1994-10-15

1988-12-13 Application filed by Miles Inc filed Critical Miles Inc

1994-10-15 Application granted granted Critical

1994-10-15 Publication of ATE112287T1 publication Critical patent/ATE112287T1/de

Links

238000002523 gelfiltration Methods 0.000 title abstract 3
238000001556 precipitation Methods 0.000 abstract 2
102100026735 Coagulation factor VIII Human genes 0.000 abstract 1
101000911390 Homo sapiens Coagulation factor VIII Proteins 0.000 abstract 1
241000700605 Viruses Species 0.000 abstract 1
229910021502 aluminium hydroxide Inorganic materials 0.000 abstract 1
WNROFYMDJYEPJX-UHFFFAOYSA-K aluminium hydroxide Chemical compound [OH-].[OH-].[OH-].[Al+3] WNROFYMDJYEPJX-UHFFFAOYSA-K 0.000 abstract 1
229910001679 gibbsite Inorganic materials 0.000 abstract 1
230000002779 inactivation Effects 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
238000001179 sorption measurement Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Genetics & Genomics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Zoology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
General Health & Medical Sciences (AREA)
Toxicology (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Gastroenterology & Hepatology (AREA)
Hematology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Solid-Sorbent Or Filter-Aiding Compositions (AREA)
Compounds Of Unknown Constitution (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
External Artificial Organs (AREA)
Injection Moulding Of Plastics Or The Like (AREA)
Orthopedics, Nursing, And Contraception (AREA)

AT88120808T 1987-12-21 1988-12-13 Faktor viii- gelfiltration. ATE112287T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US13596687A	1987-12-21	1987-12-21

Publications (1)

Publication Number	Publication Date
ATE112287T1 true ATE112287T1 (de)	1994-10-15

Family

ID=22470609

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT88120808T ATE112287T1 (de)	1987-12-21	1988-12-13	Faktor viii- gelfiltration.

Country Status (6)

Country	Link
EP (1)	EP0321835B1 (de)
JP (1)	JP2689390B2 (de)
AT (1)	ATE112287T1 (de)
AU (1)	AU626275B2 (de)
CA (1)	CA1339477C (de)
DE (1)	DE3851696T2 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK162233C (da) *	1989-11-09	1992-03-16	Novo Nordisk As	Fremgangsmaade til isolering af faktor viii fra blodplasma og pharmaceutisk praeparat indeholdende den saaledes isolerede fator viii
DE4001099A1 (de) *	1990-01-17	1991-07-18	Octapharma Ag	Verfahren zur entfernung von viren aus biologischen fluessigkeiten
US5278289A (en) *	1991-11-12	1994-01-11	Johnson Alan J	Antihemophilic factor stabilization
US5288853A (en) *	1992-04-30	1994-02-22	Alpha Therapeutic Corporation	Factor viii purification process
DE10246125A1 (de) *	2002-10-01	2004-04-15	Aventis Behring Gmbh	Konzentrat eines Faktor VIII:C-haltigen von-Willebrand-Faktors und das dazu gehörige Verfahren

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4361509A (en) *	1981-12-14	1982-11-30	Scripps Clinic And Research Foundation	Ultrapurification of factor VIII using monoclonal antibodies
US4495175A (en) *	1982-08-05	1985-01-22	University Of Rochester	Preparation of highly purified human antihemophilic factor
US4534972A (en) *	1983-03-29	1985-08-13	Miles Laboratories, Inc.	Protein compositions substantially free from infectious agents
DE3481109D1 (de) *	1983-05-09	1990-03-01	Novo Nordisk As	Antihaemophilie-faktor-viii-konzentrat und dessen herstellungsverfahren.
US4540573A (en) *	1983-07-14	1985-09-10	New York Blood Center, Inc.	Undenatured virus-free biologically active protein derivatives
US4543210A (en) *	1984-10-04	1985-09-24	Miles Laboratories, Inc.	Process for producing a high purity antihemophilic factor concentrate
US4758657A (en) *	1985-07-11	1988-07-19	Armour Pharmaceutical Company	Method of purifying Factor VIII:C
JPS62195331A (ja) *	1986-02-24	1987-08-28	Nippon Sekijiyuujishiya	血液凝固第８因子製剤の製法

1988
- 1988-12-13 DE DE3851696T patent/DE3851696T2/de not_active Expired - Lifetime
- 1988-12-13 AT AT88120808T patent/ATE112287T1/de not_active IP Right Cessation
- 1988-12-13 EP EP88120808A patent/EP0321835B1/de not_active Expired - Lifetime
- 1988-12-16 JP JP63316557A patent/JP2689390B2/ja not_active Expired - Lifetime
- 1988-12-20 CA CA000586473A patent/CA1339477C/en not_active Expired - Lifetime
- 1988-12-20 AU AU27310/88A patent/AU626275B2/en not_active Expired

Also Published As

Publication number	Publication date
JPH01301625A (ja)	1989-12-05
DE3851696D1 (de)	1994-11-03
EP0321835A2 (de)	1989-06-28
DE3851696T2 (de)	1995-02-23
EP0321835A3 (en)	1990-04-11
JP2689390B2 (ja)	1997-12-10
AU2731088A (en)	1989-06-22
CA1339477C (en)	1997-09-23
EP0321835B1 (de)	1994-09-28
AU626275B2 (en)	1992-07-30

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Legal Events

Date	Code	Title	Description
2009-03-15	EELA	Cancelled due to lapse of time