ATE90875T1 - Gelfiltration von waermebehandeltem faktor viii. - Google Patents

Gelfiltration von waermebehandeltem faktor viii.

Info

Publication number: ATE90875T1
Authority: AT; Austria
Prior art keywords: gel filtration; heat; factor viii; treated factor; peg precipitation
Prior art date: 1989-05-24

Application number

AT90108993T

Other languages

English (en)

Inventor

Christian Dr Goelker

Bernd Dr Bockskopf

William Brockway

Richard L Seng

Original Assignee

Miles Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-05-24

Filing date

1990-05-12

Publication date

1993-07-15

1990-05-12 Application filed by Miles Inc filed Critical Miles Inc

1993-07-15 Application granted granted Critical

1993-07-15 Publication of ATE90875T1 publication Critical patent/ATE90875T1/de

Links

238000002523 gelfiltration Methods 0.000 title abstract 3
229960000301 factor viii Drugs 0.000 title 1
238000001556 precipitation Methods 0.000 abstract 2
102100026735 Coagulation factor VIII Human genes 0.000 abstract 1
101000911390 Homo sapiens Coagulation factor VIII Proteins 0.000 abstract 1
241000700605 Viruses Species 0.000 abstract 1
229910021502 aluminium hydroxide Inorganic materials 0.000 abstract 1
WNROFYMDJYEPJX-UHFFFAOYSA-K aluminium hydroxide Chemical compound [OH-].[OH-].[OH-].[Al+3] WNROFYMDJYEPJX-UHFFFAOYSA-K 0.000 abstract 1
229910001679 gibbsite Inorganic materials 0.000 abstract 1
230000002779 inactivation Effects 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
238000001179 sorption measurement Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Genetics & Genomics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Zoology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
General Health & Medical Sciences (AREA)
Toxicology (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Gastroenterology & Hepatology (AREA)
Hematology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Solid-Sorbent Or Filter-Aiding Compositions (AREA)
Distillation Of Fermentation Liquor, Processing Of Alcohols, Vinegar And Beer (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Separation By Low-Temperature Treatments (AREA)

AT90108993T 1989-05-24 1990-05-12 Gelfiltration von waermebehandeltem faktor viii. ATE90875T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US35631589A	1989-05-24	1989-05-24

Publications (1)

Publication Number	Publication Date
ATE90875T1 true ATE90875T1 (de)	1993-07-15

Family

ID=23400965

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT90108993T ATE90875T1 (de)	1989-05-24	1990-05-12	Gelfiltration von waermebehandeltem faktor viii.

Country Status (8)

Country	Link
EP (1)	EP0399321B1 (de)
JP (1)	JP2931630B2 (de)
AT (1)	ATE90875T1 (de)
AU (1)	AU635535B2 (de)
CA (1)	CA2017039C (de)
DE (1)	DE69002033T2 (de)
DK (1)	DK0399321T3 (de)
ES (1)	ES2042138T3 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK162233C (da) *	1989-11-09	1992-03-16	Novo Nordisk As	Fremgangsmaade til isolering af faktor viii fra blodplasma og pharmaceutisk praeparat indeholdende den saaledes isolerede fator viii
DE4434538C2 (de) *	1993-10-06	2000-08-10	Immuno Ag	Verfahren zur Virusinaktivierung in Gegenwart eines Polyethers und eines chaotropen Agens
HRP940645A2 (en) *	1993-10-06	1996-12-31	Immuno Ag	Process for virus deactivation in the presence of polyalkylene glycol and the pharmaceutical preparation thus obtained
US6632648B1 (en)	1996-05-14	2003-10-14	Elan Drug Delivery Limited	Methods of terminal sterilization of fibrinogen
CA2634663C (en)	1999-02-22	2009-08-25	University Of Connecticut	Novel albumin-free factor viii formulations
US6964764B2 (en)	1999-11-13	2005-11-15	Talecris Biotherapeutics, Inc.	Method of thrombolysis by local delivery of reversibly inactivated acidified plasmin
US7544500B2 (en)	1999-11-13	2009-06-09	Talecris Biotherapeutics, Inc.	Process for the production of a reversibly inactive acidified plasmin composition
US6969515B2 (en)	1999-11-13	2005-11-29	Talecris Biotherapeutics, Inc.	Method of thrombolysis by local delivery of reversibly inactivated acidified plasmin
US6355243B1 (en)	1999-11-13	2002-03-12	Bayer Corporation	Method of thrombolysis by local delivery of active plasmin
NZ589557A (en)	2008-06-04	2012-08-31	Talecris Biotherapeutics Inc	Immobilised streptokinase, method and kit for preparing plasmin
EP2385825B1 (de)	2008-11-07	2018-10-10	University of Connecticut	Faktor-viii-formulierungen
HUE025670T2 (en)	2009-03-03	2016-04-28	Grifols Therapeutics Inc	A method for producing plasminogen
JP7253505B2 (ja)	2017-06-23	2023-04-06	武田薬品工業株式会社	第ｖｉｉｉ因子亜種の精製

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3631018A (en) *	1970-05-01	1971-12-28	Baxter Laboratories Inc	Production of stable high-potency human ahf using polyethylene glycol and glycine to fractionate a cryoprecipitate of ahf concentrate
US4069216A (en) *	1975-06-16	1978-01-17	Edward Shanbrom, Inc.	Simplified methods for preparation of very high purity Factor VIII concentrate
US4170639A (en) *	1978-07-10	1979-10-09	Warner-Lambert Company	Antihemophilic factor concentrate and its production
FR2460305A2 (fr) *	1979-06-29	1981-01-23	Merieux Inst	Procede de preparation d'un concentre de facteur viii
US4305871A (en) *	1980-09-02	1981-12-15	Edward Shanbrom	Method of selectively increasing yield and purity of certain cryoprecipitate proteins by heating
DE3481109D1 (de) *	1983-05-09	1990-03-01	Novo Nordisk As	Antihaemophilie-faktor-viii-konzentrat und dessen herstellungsverfahren.
US4543210A (en) *	1984-10-04	1985-09-24	Miles Laboratories, Inc.	Process for producing a high purity antihemophilic factor concentrate
AU6487286A (en) *	1985-11-08	1987-05-14	Baxter Travenol Laboratories Inc.	Antihemophilic factor by cold precipitation
FR2651437A1 (fr) *	1989-09-05	1991-03-08	Lille Transfusion Sanguine	Procede de preparation de concentre du complexe facteur viii-facteur von willebrand de la coagulation sanguine a partir de plasma total.
DK162233C (da) *	1989-11-09	1992-03-16	Novo Nordisk As	Fremgangsmaade til isolering af faktor viii fra blodplasma og pharmaceutisk praeparat indeholdende den saaledes isolerede fator viii

1990
- 1990-05-12 DK DK90108993.8T patent/DK0399321T3/da active
- 1990-05-12 AT AT90108993T patent/ATE90875T1/de not_active IP Right Cessation
- 1990-05-12 DE DE90108993T patent/DE69002033T2/de not_active Expired - Lifetime
- 1990-05-12 EP EP90108993A patent/EP0399321B1/de not_active Expired - Lifetime
- 1990-05-12 ES ES199090108993T patent/ES2042138T3/es not_active Expired - Lifetime
- 1990-05-17 CA CA002017039A patent/CA2017039C/en not_active Expired - Lifetime
- 1990-05-23 AU AU55868/90A patent/AU635535B2/en not_active Expired
- 1990-05-23 JP JP2133691A patent/JP2931630B2/ja not_active Expired - Lifetime

Also Published As

Publication number	Publication date
AU635535B2 (en)	1993-03-25
ES2042138T3 (es)	1993-12-01
DE69002033D1 (de)	1993-07-29
JP2931630B2 (ja)	1999-08-09
CA2017039C (en)	1999-08-03
DK0399321T3 (da)	1993-08-09
EP0399321A3 (de)	1991-07-17
EP0399321B1 (de)	1993-06-23
AU5586890A (en)	1990-11-29
EP0399321A2 (de)	1990-11-28
JPH0347199A (ja)	1991-02-28
DE69002033T2 (de)	1993-09-30
CA2017039A1 (en)	1990-11-24

Legal Events

Date	Code	Title	Description
2010-08-15	EELA	Cancelled due to lapse of time

Publication	Publication Date	Title
DE69002033D1 (de)	1993-07-29	Gelfiltration von waermebehandeltem faktor viii.
GR3026751T3 (en)	1998-07-31	Process for producing collagen fibres
DE59209735D1 (de)	1999-09-23	Durch Hitze und/oder Detergens virusinaktiviertes Blutprodukt
IT1214505B (it)	1990-01-18	Procedimento per la preparazione di collageno e prodotti cosi'ottenuto.
DE3781133D1 (de)	1992-09-17	Herstellung von polymilchsaeure und copolymeren daraus.
DE69637181D1 (de)	2007-09-06	Vorrichtung zur inaktivierung von viralen kontaminationen in blutprodukten
DE69127694D1 (de)	1997-10-23	Herstellung und verwendung von transfer-faktor
ATE166881T1 (de)	1998-06-15	Verfahren zur herstellung von faktor viii
ITMI922778A1 (it)	1994-06-04	Processo per l'estrazione del complesso fattore viii-fattore von willebrand (fviii: c-fvw) da plasma umano totale.
DE3851696D1 (de)	1994-11-03	Faktor VIII- Gelfiltration.
ATE94882T1 (de)	1993-10-15	Heparinbindende gehirnmitogene.
DE68928634D1 (de)	1998-05-14	Verfahren zur Herstellung von aktivierten Killer-Monozyten und Verfahren zur Überprüfung ihrer tumoriziden Aktivität
FI903143A0 (fi)	1990-06-21	Menetelmä ihmisen nuhaviruksen serotyypittämiseksi
ATE81496T1 (de)	1992-10-15	Verfahren zur reinigung von dihydroxybiphenylen.
IT1256237B (it)	1995-11-29	Procedimento per la preparazione di acyclovir