ATE113664T1 - Zusammensetzung, vorrichtung und verfahren zur untersuchung einer peroxidativ aktiven substanz. - Google Patents
Zusammensetzung, vorrichtung und verfahren zur untersuchung einer peroxidativ aktiven substanz.Info
- Publication number
- ATE113664T1 ATE113664T1 AT90124220T AT90124220T ATE113664T1 AT E113664 T1 ATE113664 T1 AT E113664T1 AT 90124220 T AT90124220 T AT 90124220T AT 90124220 T AT90124220 T AT 90124220T AT E113664 T1 ATE113664 T1 AT E113664T1
- Authority
- AT
- Austria
- Prior art keywords
- active substance
- indicator
- improved
- composition
- peroxidatively active
- Prior art date
Links
- 239000013543 active substance Substances 0.000 title abstract 4
- 239000000203 mixture Substances 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 3
- 230000003617 peroxidasic effect Effects 0.000 title 1
- 238000003556 assay Methods 0.000 abstract 2
- 239000003153 chemical reaction reagent Substances 0.000 abstract 2
- 239000011159 matrix material Substances 0.000 abstract 2
- 102000001554 Hemoglobins Human genes 0.000 abstract 1
- 108010054147 Hemoglobins Proteins 0.000 abstract 1
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 abstract 1
- -1 amine borate compound Chemical class 0.000 abstract 1
- HFACYLZERDEVSX-UHFFFAOYSA-N benzidine Chemical compound C1=CC(N)=CC=C1C1=CC=C(N)C=C1 HFACYLZERDEVSX-UHFFFAOYSA-N 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 239000002824 redox indicator Substances 0.000 abstract 1
- 210000002700 urine Anatomy 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
- C12Q1/28—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving peroxidase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
- G01N33/721—Haemoglobin
- G01N33/725—Haemoglobin using peroxidative activity
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2326/00—Chromogens for determinations of oxidoreductase enzymes
- C12Q2326/10—Benzidines
- C12Q2326/12—3,3',5,5'-Tetramethylbenzidine, i.e. TMB
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/805—Test papers
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/904—Oxidation - reduction indicators
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/25125—Digestion or removing interfering materials
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Organic Chemistry (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/472,282 US5089420A (en) | 1990-01-30 | 1990-01-30 | Composition, device and method of assaying for a peroxidatively active substance utilizing amine borate compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE113664T1 true ATE113664T1 (de) | 1994-11-15 |
Family
ID=23874869
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT90124220T ATE113664T1 (de) | 1990-01-30 | 1990-12-14 | Zusammensetzung, vorrichtung und verfahren zur untersuchung einer peroxidativ aktiven substanz. |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US5089420A (de) |
| EP (1) | EP0444273B1 (de) |
| JP (1) | JP2928649B2 (de) |
| KR (1) | KR0163792B1 (de) |
| AT (1) | ATE113664T1 (de) |
| AU (1) | AU621510B2 (de) |
| CA (1) | CA2025802A1 (de) |
| DE (1) | DE69013882T2 (de) |
| DK (1) | DK0444273T3 (de) |
| ES (1) | ES2066093T3 (de) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4024544A1 (de) * | 1990-08-02 | 1992-02-06 | Boehringer Mannheim Gmbh | Analyseelement und verfahren zu seiner herstellung |
| GB9027131D0 (en) * | 1990-12-14 | 1991-02-06 | Rice Evans Catherine | Diagnostic test |
| US5182213A (en) * | 1991-03-18 | 1993-01-26 | Miles Inc. | Method for detecting the presence of peroxidatively active substance in basic media |
| JP2704679B2 (ja) * | 1991-04-11 | 1998-01-26 | 栄研化学株式会社 | 液体試料のイオン強度又は比重測定用組成物及び該組成物を用いた試験片 |
| WO1993008684A1 (en) * | 1991-10-28 | 1993-05-13 | Steinman Gary D | Process and device for measuring magnesium in biological fluids and method of preparing the device |
| DE4202850A1 (de) * | 1992-01-31 | 1993-08-05 | Boehringer Mannheim Gmbh | Analysenelement fuer immunoassays |
| US5320969A (en) * | 1992-10-22 | 1994-06-14 | Miles Inc. | Method, composition and device for the semiquantitative determination of specific gravity of a test sample |
| US5302531A (en) * | 1992-10-22 | 1994-04-12 | Miles Inc. | Composition for the semiquantitative determination of specific gravity of a test sample |
| US5733785A (en) * | 1993-05-28 | 1998-03-31 | Chinera Research Chemical, Inc. | Automated urinalysis method for detecting blood in urine |
| US5447868A (en) * | 1993-09-14 | 1995-09-05 | Propper Manufacturing Co. Inc. | Method, reagent and kit for the detection of fecal occult blood |
| US5516645A (en) * | 1994-04-25 | 1996-05-14 | Johnson & Johnson Clinical Diagnostics, Inc. | Immunoassay analytical elements containing vanadium IV(V+4)ions |
| US5910423A (en) * | 1995-04-28 | 1999-06-08 | Ricoh Kyosan, Inc. | Water soluble powered formulation of reagent mixture containing water-insoluble reagents, and process for their production |
| US5702955A (en) * | 1995-05-22 | 1997-12-30 | Bayer Corporation | Ascorbate resistant detection of hydrogen peroxide |
| US6140368A (en) * | 1997-05-05 | 2000-10-31 | The Regents Of The University Of California | Naphthols useful in antiviral methods |
| CA2249778A1 (en) * | 1997-12-15 | 1999-06-15 | Bayer Corporation | Competitive apo-peroxidase assay |
| IL125880A (en) * | 1998-08-21 | 2000-11-21 | Fish Falk | Method for the determination of analyte concentration in blood |
| JP4618932B2 (ja) * | 2001-05-28 | 2011-01-26 | 株式会社同仁化学研究所 | 塩素濃度の測定用組成物 |
| US7459127B2 (en) * | 2002-02-26 | 2008-12-02 | Siemens Healthcare Diagnostics Inc. | Method and apparatus for precise transfer and manipulation of fluids by centrifugal and/or capillary forces |
| US7094354B2 (en) * | 2002-12-19 | 2006-08-22 | Bayer Healthcare Llc | Method and apparatus for separation of particles in a microfluidic device |
| US7125711B2 (en) * | 2002-12-19 | 2006-10-24 | Bayer Healthcare Llc | Method and apparatus for splitting of specimens into multiple channels of a microfluidic device |
| US7435381B2 (en) * | 2003-05-29 | 2008-10-14 | Siemens Healthcare Diagnostics Inc. | Packaging of microfluidic devices |
| US20040265171A1 (en) * | 2003-06-27 | 2004-12-30 | Pugia Michael J. | Method for uniform application of fluid into a reactive reagent area |
| US20080257754A1 (en) * | 2003-06-27 | 2008-10-23 | Pugia Michael J | Method and apparatus for entry of specimens into a microfluidic device |
| US20040265172A1 (en) * | 2003-06-27 | 2004-12-30 | Pugia Michael J. | Method and apparatus for entry and storage of specimens into a microfluidic device |
| US7347617B2 (en) * | 2003-08-19 | 2008-03-25 | Siemens Healthcare Diagnostics Inc. | Mixing in microfluidic devices |
| US8080423B2 (en) * | 2004-08-05 | 2011-12-20 | Asahi Kasei Pharma Corporation | Reagent containing protease reaction promoter and/or colorant stabilizer |
| JP4697809B2 (ja) * | 2007-02-22 | 2011-06-08 | 旭化成ファーマ株式会社 | ロイコ色素の安定化方法 |
| TWI368029B (en) * | 2007-10-19 | 2012-07-11 | Gen Life Biotechnology Co Ltd | Electrochemical method for detecting hemoglobin and test strip thereof |
| US7915047B2 (en) * | 2007-11-19 | 2011-03-29 | Los Alamos National Security, Llc | Coating for leak detection and method |
| JP2010189662A (ja) * | 2010-05-13 | 2010-09-02 | Asahi Kasei Pharma Kk | ロイコ色素の安定化方法 |
| JP5274590B2 (ja) * | 2011-01-27 | 2013-08-28 | 旭化成ファーマ株式会社 | ロイコ色素の安定化方法 |
| RU2458992C1 (ru) * | 2011-05-04 | 2012-08-20 | Белорусский Государственный Университет (Бгу) | Способ определения пероксидазной активности гемоглобина в плазме крови |
| MX380384B (es) * | 2014-11-18 | 2025-03-12 | Colgate Palmolive Co | Un kit que comprende una composición para detectar sangre |
| WO2020139767A1 (en) * | 2018-12-28 | 2020-07-02 | Beckman Coulter, Inc. | Methods for enhanced detection of hemoglobin |
| CN112710595B (zh) * | 2020-12-22 | 2022-10-28 | 西南石油大学 | 一种气藏储层水锁伤害实验评价方法 |
| WO2023132551A1 (ko) * | 2022-01-10 | 2023-07-13 | 주식회사 퓨쳐바이오웍스 | 동물의 소변 상태 진단용 모래, 이의 제조방법 및 이를 이용한 소변 상태 진단 방법 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2235127C2 (de) * | 1972-07-18 | 1974-08-08 | Boehringer Mannheim Gmbh, 6800 Mannheim | Diagnostisches Mittel zum Nachweis von Blut und anderen peroxidatisch wirksamen Substanzen in Körperflüssigkeiten |
| US4071321A (en) * | 1977-03-14 | 1978-01-31 | Miles Laboratories, Inc. | Test composition and device for determining peroxidatively active substances |
| US4071318A (en) * | 1977-03-14 | 1978-01-31 | Miles Laboratories, Inc. | Test composition and device for determining peroxidatively active substances |
| US4251223A (en) * | 1979-12-17 | 1981-02-17 | Miles Laboratories, Inc. | Sensitizers for peroxidative activity tests |
| US4755472A (en) * | 1986-01-16 | 1988-07-05 | Miles Inc. | Stable composition for the determination of peroxidatively active substances |
| AU2382988A (en) * | 1988-08-16 | 1990-03-23 | Cetus Corporation | Stable indicator solutions for detection of peroxidatic activity |
-
1990
- 1990-01-30 US US07/472,282 patent/US5089420A/en not_active Expired - Lifetime
- 1990-09-20 CA CA002025802A patent/CA2025802A1/en not_active Abandoned
- 1990-09-28 AU AU63659/90A patent/AU621510B2/en not_active Ceased
- 1990-12-14 DE DE69013882T patent/DE69013882T2/de not_active Expired - Fee Related
- 1990-12-14 ES ES90124220T patent/ES2066093T3/es not_active Expired - Lifetime
- 1990-12-14 EP EP90124220A patent/EP0444273B1/de not_active Expired - Lifetime
- 1990-12-14 DK DK90124220.6T patent/DK0444273T3/da active
- 1990-12-14 AT AT90124220T patent/ATE113664T1/de not_active IP Right Cessation
-
1991
- 1991-01-28 KR KR1019910001366A patent/KR0163792B1/ko not_active Expired - Fee Related
- 1991-01-29 JP JP3026724A patent/JP2928649B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| ES2066093T3 (es) | 1995-03-01 |
| DE69013882T2 (de) | 1995-03-09 |
| AU6365990A (en) | 1991-08-01 |
| KR0163792B1 (ko) | 1999-03-30 |
| JPH04213064A (ja) | 1992-08-04 |
| CA2025802A1 (en) | 1991-07-31 |
| JP2928649B2 (ja) | 1999-08-03 |
| AU621510B2 (en) | 1992-03-12 |
| DK0444273T3 (da) | 1995-04-24 |
| US5089420A (en) | 1992-02-18 |
| DE69013882D1 (de) | 1994-12-08 |
| EP0444273B1 (de) | 1994-11-02 |
| KR910014702A (ko) | 1991-08-31 |
| EP0444273A1 (de) | 1991-09-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |